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Written By Veda Maddala , M Pharmacy
Reviewed By Sureshvarma D , MPharma
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIBIOTICS

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - HIC0082

Author Details

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FAQs

Hicoly 4.5MIU Injection contains Colistimethate, an antibiotic that works by binding to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stops the leakage of cell contents. Thereby, damages bacterial cell membranes and kills bacteria.

You are not recommended to take Hicoly 4.5MIU Injection with gentamicin as co-administration of these two medicines may increase the risk of severe adverse effects such as kidney problems, hearing loss or respiratory depression especially in elderly people and in those who have preexisting kidney disease or who are dehydrated. However, please consult your doctor before taking Hicoly 4.5MIU Injection with other medicines.

Hicoly 4.5MIU Injection may cause dizziness as a common side effect. Avoid driving if you feel dizzy after taking Hicoly 4.5MIU Injection. However, if the condition persists or worsens, please consult a doctor.

Hicoly 4.5MIU Injection should be used with caution in patients receiving dialysis (the process of filtration and purification of blood using a machine). Therefore, if you are receiving dialysis, please inform your doctor before taking Hicoly 4.5MIU Injection so that the dose may be adjusted accordingly.

You are recommended to take Hicoly 4.5MIU Injection with extreme caution if you have kidney disease as it may worsen the condition. Regular monitoring of kidney functioning is recommended while taking Hicoly 4.5MIU Injection. Therefore, inform your doctor if you have any kidney problems before taking Hicoly 4.5MIU Injection.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Interaction of Hicoly 4.5MIU Injection with alcohol is unknown. Please consult a doctor before consuming alcohol while using Hicoly 4.5MIU Injection.

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Pregnancy

Caution

Hicoly 4.5MIU Injection is a category C pregnancy drug and is given to pregnant women only if it is essential. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Hicoly 4.5MIU Injection may be excreted in human milk in small amounts. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Hicoly 4.5MIU Injection may cause confusion, vision problems or dizziness. Therefore, avoid driving if you experience any of these symptoms after taking Hicoly 4.5MIU Injection.

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Liver

Caution

Take Hicoly 4.5MIU Injection with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Hicoly 4.5MIU Injection with caution, especially if you have a history of Kidney diseases/conditions as Hicoly 4.5MIU Injection may affect kidney function. The dose may be adjusted by your doctor as required.

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Children

Caution

Hicoly 4.5MIU Injection should be used with caution in children and in doses as prescribed by a doctor. Special care should be taken in new-born and premature babies as kidneys are not developed fully.

About Hicoly 4.5MIU Injection

Hicoly 4.5MIU Injection belongs to a class of drugs called antibiotics used in the treatment of severe bacterial infections. Bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. Hicoly 4.5MIU Injection does not work against infections caused by a virus.

Hicoly 4.5MIU Injection contains Colistimethate, an antibiotic that works by binding to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thereby, damaging bacterial cell membranes and kills bacteria.

Take Hicoly 4.5MIU Injection as prescribed by your doctor. You are advised to take Hicoly 4.5MIU Injection for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, stomach upset, tingling, or difficulty in breathing. Most of these side effects of Hicoly 4.5MIU Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Hicoly 4.5MIU Injection or any other medicines, please tell your doctor. If you have myasthenia gravis (muscle weakness), kidney problems, or porphyria (a disorder in the formation of red blood pigment), inform your doctor before taking Hicoly 4.5MIU Injection. If you are pregnant or breastfeeding, please inform your doctor before taking Hicoly 4.5MIU Injection. Special care should be taken in new-born and premature babies as kidneys are not developed fully. Drive only if you are alert as Hicoly 4.5MIU Injection may cause confusion, vision problems, or dizziness.  If you are on dialysis, inform your doctor before taking Hicoly 4.5MIU Injection so that the dose may be reduced accordingly.

Uses of Hicoly 4.5MIU Injection

Several bacterial infections

Medicinal Benefits Mweb

Medicinal Benefits

Hicoly 4.5MIU Injection contains Colistimethate, a narrow-spectrum antibiotic that is active against gram-negative bacteria. Hicoly 4.5MIU Injection binds to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thereby, damages bacterial cell membranes and kills bacteria. Hicoly 4.5MIU Injection is used when other antibiotics are not suitable.

Directions for Use

Hicoly 4.5MIU Injection will be administered by a healthcare professional; do not self-administer.

Side Effects of Hicoly 4.5MIU Injection

  • Dizziness
  • Stomach upset
  • Tingling
  • Difficulty in breathing

Drug Warnings

If you are allergic to Hicoly 4.5MIU Injection or any other medicines, please tell your doctor. If you have myasthenia gravis (muscle weakness), kidney problems, or porphyria (a disorder in the formation of red blood pigment), inform your doctor before taking Hicoly 4.5MIU Injection. If you are pregnant or breastfeeding, please inform your doctor before taking Hicoly 4.5MIU Injection. Special care should be taken in new-born and premature babies as kidneys are not developed fully. Drive only if you are alert as Hicoly 4.5MIU Injection may cause confusion, vision problems, or dizziness. If you are on dialysis, inform your doctor before taking Hicoly 4.5MIU Injection so that the dose may be reduced accordingly. Inform your anesthetist that you are taking Hicoly 4.5MIU Injection as it may increase the effects of muscle relaxants used in general anesthesia. You are recommended to complete the full course of Hicoly 4.5MIU Injection as prescribed by your doctor for effective results.

Drug-Drug Interactions

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ColistinBCG vaccine
Critical
ColistinNeomycin
Severe

Drug-Drug Interactions

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ColistinBCG vaccine
Critical
How does the drug interact with Hicoly 4.5MIU Injection:
Coadministration of Hicoly 4.5MIU Injection along with BCG vaccine can reduce the treatment outcomes.

How to manage the interaction:
Taking Hicoly 4.5MIU Injection with BCG vaccine is avoided as it may lead to an interaction, please consult your doctor before taking it.
ColistinNeomycin
Severe
How does the drug interact with Hicoly 4.5MIU Injection:
Combining Hicoly 4.5MIU Injection with Neomycin can increase the risk or severity of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Hicoly 4.5MIU Injection and Neomycin, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, Rash, Dizziness, or Fever, consult a doctor. Do not stop using any medications without a doctor's advice.
ColistinIohexol
Severe
How does the drug interact with Hicoly 4.5MIU Injection:
Combining Hicoly 4.5MIU Injection with Iohexol can increase the effect or side effects of Iohexol.

How to manage the interaction:
Although there is a possible interaction between Hicoly 4.5MIU Injection and Iohexol, you can take these medicines if prescribed by your doctor. However, if you experience vomiting, loss of appetite, irregular urination, swelling, shortness of breath, muscle cramps, or weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
ColistinHuman immunoglobulin
Severe
How does the drug interact with Hicoly 4.5MIU Injection:
Taking Human immunoglobulin with Hicoly 4.5MIU Injection, may raise the risk of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Human immunoglobulin and Hicoly 4.5MIU Injection, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
ColistinGentamicin
Severe
How does the drug interact with Hicoly 4.5MIU Injection:
Co-administration of Hicoly 4.5MIU Injection with Gentamicin can increase the levels and risk of Hicoly 4.5MIU Injection side effects.

How to manage the interaction:
Although there is a possible interaction between Hicoly 4.5MIU Injection and Gentamicin, you can take these medicines together if prescribed by your doctor. However, if you experience weight gain or loss suddenly, muscle pain, dizziness, or palpitations, call your doctor right away. Do not stop using any medications without a doctor's advice.
ColistinAdefovir dipivoxil
Severe
How does the drug interact with Hicoly 4.5MIU Injection:
Combining Hicoly 4.5MIU Injection with Adefovir dipivoxil may decrease Hicoly 4.5MIU Injection's excretion rate, which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Hicoly 4.5MIU Injection and Adefovir dipivoxil, you can take these medicines together if prescribed by your doctor. However, if you experience any irregular urination, swelling, shortness of breath, muscle pain, dizziness, or palpitations call your doctor right away. Do not stop using any medications without a doctor's advice.
ColistinPancuronium
Severe
How does the drug interact with Hicoly 4.5MIU Injection:
Using Pancuronium with Hicoly 4.5MIU Injection can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Hicoly 4.5MIU Injection and Pancuronium, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, rash, dizziness, or fever, consult a doctor. Do not stop using any medications without a doctor's advice.
ColistinStreptomycin
Severe
How does the drug interact with Hicoly 4.5MIU Injection:
Coadministration of Streptomycin with Hicoly 4.5MIU Injection may increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Hicoly 4.5MIU Injection and Streptomycin, you can take these medicines together if prescribed by your doctor. However, if you experience shortness of breath, muscle pain, dizziness, or palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ColistinTenofovir alafenamide
Severe
How does the drug interact with Hicoly 4.5MIU Injection:
Combining Hicoly 4.5MIU Injection with Tenofovir alafenamide may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Hicoly 4.5MIU Injection and Tenofovir alafenamide, you can take these medicines together if prescribed by your doctor. However, consult a doctor if you experience an upset stomach, rash, dizziness, or fever. Do not stop using any medications without a doctor's advice.
ColistinKanamycin
Severe
How does the drug interact with Hicoly 4.5MIU Injection:
Coadministration of Hicoly 4.5MIU Injection with Kanamycin can increase the level and risk of Hicoly 4.5MIU Injection side effects.

How to manage the interaction:
Although there is a possible interaction between Hicoly 4.5MIU Injection and Kanamycin, you can take these medicines together if prescribed by your doctor. However, if you experience shortness of breath, swelling, muscle pain, dizziness, or palpitations call your doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • AMIKACIN
  • NETILIMICIN
  • TOBRAMYCIN
  • GENTAMICIN
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • AZITHROMYCIN
  • CIPROFLOXACIN
  • NORFLOXACIN
  • OFLOXACIN

Habit Forming

No

Special Advise

  • Regular blood tests are recommended to monitor the levels of Hicoly 4.5MIU Injection in blood and kidney functioning.
  • Inform your anaesthetist that you are taking Hicoly 4.5MIU Injection as it may increase the effects of muscle relaxants used in general anaesthesia.

Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Hicoly 4.5MIU Injection to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like cheese, yogurt, kombucha, sauerkraut, and kimchi can restore the good bacteria of the intestine.
  • Include fiber-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as whole-grain bread and brown rice should be included in your diet.
  • Make sure you drink plenty of water or other fluids every day while you are taking Hicoly 4.5MIU Injection.
  • Avoid alcohol consumption as it may increase adverse effects.

Hicoly 4.5MIU Injection Substitute

Substitutes safety advice
  • Guficol 4.5miu Injection

    by AYUR

    2388.60per tablet
  • Colina 4.5miu Injection

    by AYUR

    3681.80per tablet
  • Promistin Forte 4.5million Iu Injection

    by AYUR

    5657.20per tablet
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