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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

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Composition :

IBUPROFEN-400MG

Manufacturer/Marketer :

Strava Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANALGESICS

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - IBU0020

Author Details

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FAQs

Ibuprofen 400 mg Tablet works by blocking the effect of chemical messengers (prostaglandin), thereby reducing pain and inflammation.

Diarrhoea or dehydration might be a side-effect of Ibuprofen 400 mg Tablet . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Do not take Ibuprofen 400 mg Tablet for more than 10 days unless prescribed by your doctor. Taking Ibuprofen 400 mg Tablet for longer durations or high doses may cause a heart attack or stroke. Do not exceed the dose and duration prescribed by your doctor.

Ibuprofen 400 mg Tablet may increase the risk of heart attack or stroke. Therefore, consult your doctor before taking Ibuprofen 400 mg Tablet if you have heart problems. Do not use Ibuprofen 400 mg Tablet immediately before or after bypass surgery like CABG.

Taking Ibuprofen 400 mg Tablet with or after food or milk may partially reduce stomach side effects such as indigestion.

Ibuprofen 400 mg Tablet can be used for relieving period pain and cramps if prescribed by the doctor. Do not exceed the dose and duration prescribed by your doctor.

Disclaimer

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Ibuprofen 400 mg Tablet . Alcohol intake, along with Ibuprofen 400 mg Tablet , may cause increased drowsiness and the risk of gastrointestinal ulcers and bleeding.

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Pregnancy

Unsafe

It is not recommended to take Ibuprofen 400 mg Tablet while you are pregnant, especially in the last trimester. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe you Ibuprofen 400 mg Tablet only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Ibuprofen 400 mg Tablet may pass into breast milk. Please consult your doctor if you have any concerns regarding this; your doctor will decide whether breastfeeding mothers can take Ibuprofen 400 mg Tablet or not.

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Driving

Caution

Ibuprofen 400 mg Tablet may cause drowsiness, dizziness, tiredness, and vision disturbances in some cases. So, avoid driving or operating heavy machinery if you experience any of these symptoms.

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Liver

Caution

Dose adjustment may be needed. Ibuprofen 400 mg Tablet should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Ibuprofen 400 mg Tablet should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Ibuprofen 400 mg Tablet is not recommended for children below six months of age, as the efficacy and safety have not been established.

About Ibuprofen 400 mg Tablet

Ibuprofen 400 mg Tablet belongs to the group of medications called NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) primarily used to relieve mild to moderate pain, inflammation, and fever in adults and paediatrics above 6 months of age. It helps to treat the conditions such as menstrual cramps, headache, neuralgia (nerve-related pain), migraine, back pain, dental pain, swelling and stiffness in joints and muscles, cold, and flu symptoms.
 
Ibuprofen 400 mg Tablet contains 'Ibuprofen' which works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzymes' effect, lesser prostaglandins are produced, which reduces mild to moderate pain, inflammation, and fever. 
 
Take Ibuprofen 400 mg Tablet as prescribed by your doctor. You are advised to take Ibuprofen 400 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as indigestion, diarrhoea, constipation, flatulence (gas), general weakness, and dizziness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently. 
 
Ibuprofen 400 mg Tablet may increase the chances of stomach ulcers, bleeding and the risk of heart attack or stroke. Avoid or limit the intake of alcohol while taking Ibuprofen 400 mg Tablet . Consult your doctor before taking Ibuprofen 400 mg Tablet if you are pregnant or breastfeeding; your doctor will prescribe Ibuprofen 400 mg Tablet only if the benefits outweigh the risks. Ibuprofen 400 mg Tablet may cause drowsiness, so drive with caution. Do not take Ibuprofen 400 mg Tablet for more than 10 days unless prescribed by your doctor. If your condition does not improve even after taking Ibuprofen 400 mg Tablet for 10 days, please consult your doctor. 

Uses of Ibuprofen 400 mg Tablet

Pain, Fever

Medicinal Benefits Mweb

Medicinal Benefits

Ibuprofen 400 mg Tablet belongs to the group of NSAIDs used to relieve pain and inflammation. Ibuprofen 400 mg Tablet relieves period pain, headache, neuralgia (nerve-related pain), migraine, back pain, dental pain, swelling and stiffness in joints and muscles, cold, flu, and fever symptoms. Ibuprofen 400 mg Tablet works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzymes' effect, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Besides this, it also minimizes fever due to pain and inflammatory conditions. 

Directions for Use

Tablet/capsule: Do not chew, break, or crush the tablet/capsule; swallow it as a whole with a glass of water. Syrup/Suspension/Drops: Shake the bottle well and take the prescribed dose/quantity by mouth using the measuring cup/dosing syringe/dropper.

Side Effects of Ibuprofen 400 mg Tablet

  • Indigestion
  • Diarrhoea
  • Constipation
  • Flatulence (gas)
  • Nausea
  • Rash
  • Weakness
  • Dizziness

Drug Warnings

If you have had any recent heart bypass surgery (CABG), do not use Ibuprofen 400 mg Tablet . Ibuprofen 400 mg Tablet increases the chances of stomach ulcers and bleeding, so do not exceed the dose and duration prescribed by your doctor. Consult your doctor before taking Ibuprofen 400 mg Tablet if you are pregnant or breastfeeding; your doctor will prescribe you Ibuprofen 400 mg Tablet only if the benefits outweigh the risks. Ibuprofen 400 mg Tablet may cause drowsiness, so drive with caution. Do not take Ibuprofen 400 mg Tablet for more than 10 days unless prescribed by your doctor. If your condition does not improve even after taking Ibuprofen 400 mg Tablet for 10 days, please consult your doctor. Avoid consuming alcohol with Ibuprofen 400 mg Tablet as it could lead to increased drowsiness and increase the risk of stomach bleeding. Stop taking Ibuprofen 400 mg Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take aspirin or any other NSAIDs for pain relief along with Ibuprofen 400 mg Tablet unless prescribed by the doctor.

Drug-Drug Interactions

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IbuprofenKetorolac
Critical
IbuprofenMeloxicam
Critical

Drug-Drug Interactions

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IbuprofenKetorolac
Critical
How does the drug interact with Ibuprofen 400 mg Tablet 400 mg Tablet:
Taking Ketorolac and Ibuprofen 400 mg Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Taking Ketorolac and Ibuprofen 400 mg Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenMeloxicam
Critical
How does the drug interact with Ibuprofen 400 mg Tablet 400 mg Tablet:
Combining Meloxicam and Ibuprofen 400 mg Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Meloxicam and Ibuprofen 400 mg Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenDasatinib
Severe
How does the drug interact with Ibuprofen 400 mg Tablet 400 mg Tablet:
Coadministration of Dasatinib and Ibuprofen 400 mg Tablet can increase the risk of bleeding.

How to manage the interaction:
Using Dasatinib and Ibuprofen 400 mg Tablet together can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like bruising, headache, dizziness, or weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenFenoprofen
Severe
How does the drug interact with Ibuprofen 400 mg Tablet 400 mg Tablet:
The combined use of Fenoprofen and Ibuprofen 400 mg Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Fenoprofen and Ibuprofen 400 mg Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising,dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenSirolimus
Severe
How does the drug interact with Ibuprofen 400 mg Tablet 400 mg Tablet:
Co-administration of Sirolimus and Ibuprofen 400 mg Tablet together increases the risk or severity of kidney problems.

How to manage the interaction:
Co-administration of Sirolimus and Ibuprofen 400 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, irregular heart rhythm, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenPrednisolone
Severe
How does the drug interact with Ibuprofen 400 mg Tablet 400 mg Tablet:
Co-administration of Prednisolone and Ibuprofen 400 mg Tablet can increase the risk of side effects of each other.

How to manage the interaction:
A combination of Prednisolone and Ibuprofen 400 mg Tablet can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
IbuprofenTeriflunomide
Severe
How does the drug interact with Ibuprofen 400 mg Tablet 400 mg Tablet:
The combined use of Teriflunomide and Ibuprofen 400 mg Tablet can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Ibuprofen 400 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light- colored stools, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenMethotrexate
Severe
How does the drug interact with Ibuprofen 400 mg Tablet 400 mg Tablet:
Coadministration of methotrexate with Ibuprofen 400 mg Tablet can increase the effect and side effects of methotrexate.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Ibuprofen 400 mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, pallor, dizziness or fainting, unusual bruising or bleeding, seizures, infection; as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
IbuprofenIndometacin
Severe
How does the drug interact with Ibuprofen 400 mg Tablet 400 mg Tablet:
The combined use of Indometacin and Ibuprofen 400 mg Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Indometacin and Ibuprofen 400 mg Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenHuman immunoglobulin
Severe
How does the drug interact with Ibuprofen 400 mg Tablet 400 mg Tablet:
Taking Human immunoglobulin with Ibuprofen 400 mg Tablet may raise the risk of kidney problems.

How to manage the interaction:
Co-administration of Human immunoglobulin with Ibuprofen 400 mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ASPIRIN
  • NAPROXEN
  • DULOXETINE
  • SERTRALINE
  • ESCITALOPRAM
  • MELOXICAM
  • FLUOXETINE

Habit Forming

No

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy. Apply a cold or hot compress on the joints for 15-20 minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid alcohol consumption.

Ibuprofen 400 mg Tablet Substitute

Substitutes safety advice
  • Brufen 400 Tablet 15's

    by Others

    1.20per tablet
  • Eurobuf 400mg Tablet

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    0.51per tablet
  • Fla 4 400mg Tablet

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    0.81per tablet
  • Danaibu 400mg Tablet

    by Others

    1.03per tablet
  • Brufen 400 Tablet 20's

    by Others

    1.32per tablet
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