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Alcohol
Caution
The interaction of alcohol with Icufos 4Gm Infusion is unknown. Hence, avoid or limit alcohol consumption while on treatment with Icufos 4Gm Infusion.
Pregnancy
Safe if prescribed
Icufos 4Gm Infusion is considered safe to be used in pregnancy. However, if you are pregnant, inform your doctor before receiving Icufos 4Gm Infusion. Your doctor prescribes this medicine if the benefits outweigh the risks.
Breast Feeding
Safe if prescribed
Small amounts of Icufos 4Gm Infusion are excreted in human milk. Therefore, it is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.
Driving
Caution
Icufos 4Gm Infusion may cause weakness or confusion in some people. Therefore, avoid driving if you notice any of these symptoms after taking Icufos 4Gm Infusion.
Liver
Caution
Please consult a doctor if you have a history of liver diseases/conditions.
Kidney
Caution
Take Icufos 4Gm Infusion with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
Caution
Icufos 4Gm Infusion may be used with caution in children if prescribed by a doctor, and the dose depends on the child’s age and weight.
Drug-Drug Interactions
Drug-Drug Interactions
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Co-administration of the Cholera vaccine with Icufos 4Gm Infusion may reduce the activity of the Cholera vaccine.
How to manage the interaction:
If you are currently being treated with Icufos 4Gm Infusion or have been treated within the last 14 days, inform your doctor before receiving cholera vaccine, live. Avoid receiving cholera vaccine, live until at least 14 days after you complete your antibiotic therapy to ensure adequate vaccine response.
When BCG vaccine is used with Icufos 4Gm Infusion, its effectiveness may be reduced.
How to manage the interaction:
Taking Icufos 4Gm Infusion with the BCG vaccine can lead to an interaction, please consult a doctor before taking it.
Icufos 4Gm Infusion may reduce the effect of balsalazide when taken orally.
How to manage the interaction:
If you are supposed to take Icufos 4Gm Infusion and Balsalazide together, your doctor may adjust the dose or monitor you more frequently to use both medications safely.
Drug-Food Interactions
Drug-Food Interactions
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Drug-Diseases Interactions
Drug-Diseases Interactions
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Nearly all antibacterial medications have been associated with Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis, which can range in severity from mild diarrhoea to deadly colitis. Lincomycin and clindamycin are typically to blame. Antibacterial treatment disrupts the colon's normal flora, promoting the growth of C difficile, whose toxins A and B contribute to the emergence of CDAD. When C difficile strains produce hypertoxins, morbidity and death rise; severe infections may not respond to antibiotic therapy and may necessitate colectomy. All individuals who get diarrhoea after taking an antibiotic must be evaluated for CDAD. Careful medical history is required because CDAD has been known to happen more than two months following antibiotic use. Broad-spectrum antibiotics and other medications with potent antibacterial properties should be used in therapy.
How to manage the interaction:
Icufos 4Gm Infusion should be used with caution in patients with a history of gastrointestinal disease, particularly colitis (inflammation of the large intestine), pseudomembranous colitis (generally characterized by severe, persistent diarrhoea and severe abdominal cramps, and sometimes associated with the passage of blood and mucus).
Hemodialysis removes Icufos 4Gm Infusion, therefore it needs to be given after treatments.
How to manage the interaction:
As Icufos 4Gm Infusion is removed by hemodialysis, it should be administered after dialysis sessions.
Icufos 4Gm Infusion is excreted intact in the faeces (18%) and by the kidneys (38%) of healthy adults. In patients with impaired renal function, the excretion of Icufos 4Gm Infusion is greatly reduced, and the half-life is prolonged. In patients with renal insufficiency, side symptoms (such as diarrhoea, headache, nausea, and vaginitis) may last longer.
How to manage the interaction:
Icufos 4Gm Infusion should be used with caution in patients with kidney failure. However, if the side effects, such as headache, diarrhoea, nausea, and vaginitis (inflammation or infection of the vagina) worsen, please consult your doctor.
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