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  1. Home
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  3. Imutrex 10 mg Tablet 4's

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
48 Hrs returnable
Know More
COD available

Online payment accepted

Imutrex 10 mg Tablet 4's, Pack of 4 TabletS
Imutrex 10 mg Tablet 4's, Pack of 4 TabletS
rxMedicinePrescription drug

Whats That

tooltip

Composition :

METHOTREXATE-10MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

Therapeutic Class

IMMUNOSUPPRESSANTS

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - IMU0003

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Aug 20, 2024 | 12:51 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Imutrex 10 mg Tablet acts as an immunosuppressant, which helps in reducing inflammation and prevents joint stiffness, thereby providing relief from rheumatoid arthritis.

Imutrex 10 mg Tablet works by suppressing the overactive immune system that is responsible for causing psoriasis. Imutrex 10 mg Tablet interferes with the synthesis of genetic material (DNA) and the growth of cells that multiply faster than usual, thereby helping in treating psoriasis and psoriatic arthritis.

Diarrhoea might be a side-effect of Imutrex 10 mg Tablet. Stop taking Imutrex 10 mg Tablet and consult your doctor if you have diarrhoea. Do not take anti-diarrheal medicine on your own.

Imutrex 10 mg Tablet can affect egg and sperm production and could lead to birth defects. Women of child-bearing potential and men using Imutrex 10 mg Tablet must use effective contraception while on treatment with Imutrex 10 mg Tablet and for at least six months after stopping the treatment. Imutrex 10 mg Tablet can lead to infertility. Therefore male patients are advised to talk with their doctor regarding the possibility of sperm preservation before starting the treatment with Imutrex 10 mg Tablet.

Imutrex 10 mg Tablet causes leukopenia (decreased number of white blood cells) and hence may make you more susceptible to infections. Consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Imutrex 10 mg Tablet may cause mouth sores. Stop taking Imutrex 10 mg Tablet and consult your doctor if you have sores in the mouth. Your doctor may recommend folate supplements to treat mouth sores.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Imutrex 10 mg Tablet.

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Pregnancy

Unsafe

Imutrex 10 mg Tablet may cause serious birth defects. It is not recommended to take Imutrex 10 mg Tablet while you are pregnant.

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Breast Feeding

Unsafe

Imutrex 10 mg Tablet passes into breast milk. Avoid breastfeeding whilst on treatment with Imutrex 10 mg Tablet.

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Driving

Caution

Imutrex 10 mg Tablet may cause dizziness and tiredness; do not drive or operate heavy machinery if you experience these symptoms.

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Liver

Caution

Do not take Imutrex 10 mg Tablet if you have chronic liver disease. Please consult your doctor if you have liver impairment before taking Imutrex 10 mg Tablet.

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Kidney

Caution

Please consult your doctor if you have kidney impairment before taking Imutrex 10 mg Tablet.

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Children

Caution

Imutrex 10 mg Tablet should be used with caution in children and only if prescribed by the doctor.

Product Substitutes

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/011719s117lbl.pdfhttp://www.hpra.ie/img/uploaded/swedocuments/pil-2167015-11052016181932-635985875740562500.pdf
  2. https://www.cipla.com/sites/default/files/Methotrexate%202.5%20mg%20%E2%80%93%20Patient%20Card%20-%20Risk%20Minimisation%20Information%20for%20Patients.pdf
  3. https://www.stmarkshospital.nhs.uk/wp-content/uploads/2014/07/IBD_methotrexate_leaflet.pdf
  4. https://www.drugs.com/methotrexate.html
  5. https://medlineplus.gov/druginfo/meds/a682019.html

About Imutrex 10 mg Tablet

Imutrex 10 mg Tablet belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat active rheumatoid arthritis, including polyarticular juvenile rheumatoid arthritis, severe psoriasis, and severe psoriatic arthritis. Imutrex 10 mg Tablet is used alone or in combination with other medicines to treat breast cancer, lung cancer, head and neck cancer, mycosis fungoides (type of blood cancer), and advanced stage non-Hodgkin's lymphomas (cancer that starts in the lymphatic system).

Imutrex 10 mg Tablet contains 'Methotrexate' that works by interrupting the processes of the immune system that cause inflammation in the joint tissues. It reduces pain and inflammation and delays joint damage and disease progression over time. Besides this, Imutrex 10 mg Tablet prevents and stops the growth of cancer cells, thereby helps treat cancer. Imutrex 10 mg Tablet treats psoriasis by suppressing the overactive immune system that is responsible for causing psoriasis.

In some cases, Imutrex 10 mg Tablet may cause common side-effects such as nausea, vomiting, diarrhoea, unusual fatigue, dizziness, headache, loss of appetite, lowered resistance to infections, tingling sensation, leukopenia (decreased number of white blood cells), and soreness of mouth and lips. You are advised to talk to your doctor if you experience these side effects persistently.

Take Imutrex 10 mg Tablet exactly as prescribed by the doctor; daily intake of Imutrex 10 mg Tablet could lead to serious toxic effects. Do not take Imutrex 10 mg Tablet if you are pregnant or breastfeeding. Imutrex 10 mg Tablet may cause dizziness and fatigue, so drive only if you are alert. Avoid consuming alcohol whilst on treatment with Imutrex 10 mg Tablet. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. Inform your doctor about your medications and health condition to rule out any unpleasant side effects/interactions.

Uses of Imutrex 10 mg Tablet

Rheumatoid arthritis, Psoriatic arthritis, Psoriasis, Cancer

Medicinal Benefits Mweb

Medicinal Benefits

Imutrex 10 mg Tablet belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat active rheumatoid arthritis, including polyarticular juvenile rheumatoid arthritis (arthritis in children), severe psoriasis, and severe psoriatic arthritis. Imutrex 10 mg Tablet helps treat rheumatoid arthritis and psoriatic arthritis by interrupting the processes of the immune system that cause inflammation in the joint tissues. It reduces pain and inflammation and delays joint damage and disease progression over time. Imutrex 10 mg Tablet treats psoriasis by suppressing the overactive immune system that is responsible for causing psoriasis. Imutrex 10 mg Tablet is used alone or in combination with other medicines to treat breast cancer, lung cancer, head and neck cancer, mycosis fungoides (type of blood cancer), and advanced stage non-Hodgkin's lymphomas (cancer that starts in the lymphatic system). Imutrex 10 mg Tablet prevents and stops the growth of cancer cells by interfering with DNA production. Imutrex 10 mg Tablet may also be used to treat inflammatory bowel disease.

Directions for Use

Imutrex 10 mg Tablet should be taken exactly as prescribed by the doctor. Tablet/capsule: Take it one hour after food in the evening or as advised by the doctor. Swallow the tablet/capsule as a whole with a glass of water whilst standing or sitting upright; do not break or chew it. Oral solution: Take the prescribed quantity by mouth using the dosing syringe.

Side Effects of Imutrex 10 mg Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Unusual fatigue
  • Dizziness
  • Headache
  • Loss of appetite
  • Elevated liver enzymes
  • Lowered resistance to infections
  • Tingling sensation
  • Leukopenia (decreased number of white blood cells)
  • Soreness of mouth and lips

Drug Warnings

Do not take Imutrex 10 mg Tablet if you are allergic to any of its contents; if you have immunodeficiency conditions, bone marrow problems, low white blood cell count, low platelet count, serious anaemia, liver problems due to alcohol abuse, chronic liver disease; if you are pregnant or breastfeeding. Talk to your doctor before taking Imutrex 10 mg Tablet if you have/had liver or kidney problems, ulceration in the stomach or bowels, poor general condition, received any vaccinations or if you are due to have any vaccinations, diabetes, ascites (fluid in the stomach area), lung problems or fluid in the lungs. Imutrex 10 mg Tablet may cause dizziness and fatigue, so drive only if you are alert. Take Imutrex 10 mg Tablet exactly as directed by the doctor as it may cause serious problems if not taken in the dose and duration prescribed by the doctor. Stop taking Imutrex 10 mg Tablet and consult your doctor immediately if you have mouth sores, diarrhoea, a fever, dehydration, cough, bleeding, shortness of breath, any signs of infection, or a skin rash.

Drug-Drug Interactions

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MethotrexateEtretinate
Critical
MethotrexateAmpicillin
Severe

Drug-Drug Interactions

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MethotrexateEtretinate
Critical
How does the drug interact with Imutrex 10 mg Tablet:
Co-administration of Etretinate with Imutrex 10 mg Tablet may increase the risk or severity of liver problems.

How to manage the interaction:
Taking Etretinate with Imutrex 10 mg Tablet is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
MethotrexateAmpicillin
Severe
How does the drug interact with Imutrex 10 mg Tablet:
Co-administration of Imutrex 10 mg Tablet with Ampicillin can increase the levels and side effects of Imutrex 10 mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Imutrex 10 mg Tablet and ampicillin, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as tiredness, dizziness, fainting, unusual bleeding or bruising, chills, fever, sore throat, body pains. Consult a doctor immediately. Do not stop using medications without a doctor's advice.
MethotrexateIbuprofen
Severe
How does the drug interact with Imutrex 10 mg Tablet:
Coadministration of Imutrex 10 mg Tablet with ibuprofen can increase the effect and side effects of Imutrex 10 mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Imutrex 10 mg Tablet and ibuprofen, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, pallor, dizziness or fainting, unusual bruising or bleeding, seizures, infection; as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
MethotrexateEsomeprazole
Severe
How does the drug interact with Imutrex 10 mg Tablet:
Co-administration of Imutrex 10 mg Tablet and esomeprazole can increase the blood levels and side effects of Imutrex 10 mg Tablet.

How to manage the interaction:
Although taking Esomeprazole with Imutrex 10 mg Tablet can result in an interaction, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience headache, dizziness, nausea and vomiting. Do not discontinue any medications without consulting a doctor.
MethotrexateKetorolac
Severe
How does the drug interact with Imutrex 10 mg Tablet:
Coadministration of Imutrex 10 mg Tablet with ketorolac can increase the blood levels and side effects of Imutrex 10 mg Tablet.

How to manage the interaction:
Although there is a interaction between Imutrex 10 mg Tablet and ketorolac, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, pallor, dizziness or fainting, unusual bruising or bleeding, seizures, infection; as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
MethotrexateRabeprazole
Severe
How does the drug interact with Imutrex 10 mg Tablet:
Co-administration of Imutrex 10 mg Tablet with Rabeprazole can increase the blood levels and side effects of Imutrex 10 mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Rabeprazole and Imutrex 10 mg Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
MethotrexateEtanercept
Severe
How does the drug interact with Imutrex 10 mg Tablet:
Co-administration of Imutrex 10 mg Tablet with etanercept can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between etanercept and Imutrex 10 mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, and pain or burning during urination, Consult a doctor. Do not stop using any medications without consulting a doctor.
MethotrexateTolmetin
Severe
How does the drug interact with Imutrex 10 mg Tablet:
Coadministration of Imutrex 10 mg Tablet with tolmetin can increase the levels and side effects of Imutrex 10 mg Tablet.

How to manage the interaction:
Although there is a possible interaction between tolmetin and Imutrex 10 mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth ulcers or sores, vomiting, fever, chills, body aches, sore throat, muscle weakness, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, breathing difficulty, dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, seizures(fits), Consult a doctor. Do not stop using any medications without consulting a doctor.
MethotrexateDicloxacillin
Severe
How does the drug interact with Imutrex 10 mg Tablet:
Co-administration of Imutrex 10 mg Tablet with dicloxacillin can increase the levels and effects of Imutrex 10 mg Tablet. This can increase the risk or severity of serious infections.

How to manage the interaction:
Although there is a possible interaction between Imutrex 10 mg Tablet and dicloxacillin, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, mouth ulcers, paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches. Consult a doctor immediately. Do not stop using medications without a doctor's advice.
MethotrexateProcaine benzylpenicillin
Severe
How does the drug interact with Imutrex 10 mg Tablet:
Coadministration of Imutrex 10 mg Tablet with procaine benzyl penicillin can increase the levels and side effects of Imutrex 10 mg Tablet.

How to manage the interaction:
Although there is a possible interaction between procaine benzyl penicillin and Imutrex 10 mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, mouth ulcers, paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches, or other flu-like symptoms, consult your doctor. Do not stop using any medications without consulting to a doctor.

Drug-Food Interactions

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METHOTREXATE-10MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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METHOTREXATE-10MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Caffeine may reduce the effectiveness of Imutrex 10 mg Tablet. Avoid taking caffeine while taking Imutrex 10 mg Tablet. This can increase the risk or severity of side effects.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CELECOXIB
  • ACETAMINOPHEN
  • HYDROCODONE
  • DULOXETINE
  • ETANERCEPT
  • ADALIMUMAB
  • ESOMEPRAZOLE
  • HYDROXYCHLOROQUINE

Habit Forming

No

Special Advise

  • Women of child-bearing age must use effective contraception whilst on treatment with Imutrex 10 mg Tablet and for at least 6 months after the last dose.
  • Male patients are advised to consult their doctor regarding the possibility of sperm preservation before starting the treatment as Imutrex 10 mg Tablet may cause infertility.
  • Imutrex 10 mg Tablet may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.
  • Your doctor may advise regular blood tests, kidney and liver tests to monitor your condition.
  • If you miss a dose of Imutrex 10 mg Tablet, call your doctor and ask if you should take the missed dose or not.

Diet & Lifestyle Advise

Arthritis:

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle exercises like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help reduce inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Psoriasis:

  • Include foods such as cherries, berries, leafy vegetables, salmon, sardines, and fish rich in omega-3 fatty acids.
  • Consume antioxidant-rich spices and herbs like cumin, ginger, sage and thyme.
  • Avoid processed foods, refined sugars, and fatty foods.
  • Limit intake of food that might trigger allergies, such as dairy products, soy, eggs, and nuts.
  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
  • Reducing stress and maintaining a good sleep cycle would be helpful.
  • Avoiding getting in contact with harsh soaps, detergents and rough fabrics.

Cancer:

  • Consume a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.

Imutrex 10 mg Tablet Substitute

Always consult your doctor before taking any new medications and supplements

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