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  1. Home
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  3. Indease 400mg Capsule

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
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COD available

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Indease 400mg Capsule, Pack of 1 Capsule
Indease 400mg Capsule, Pack of 1 Capsule
rxMedicinePrescription drug

Whats That

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Composition :

INDINAVIR-400MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANTIRETROVIRAL AGENTS

Manufacturer/Marketer address

1251, SECTOR-8, FARIDABAD, HARYANA
Other Info - IN63254

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 20, 2024 | 1:17 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Indease 400mg Capsule works by decreasing the amount of HIV in the blood. Thereby, Indease 400mg Capsule helps treat HIV infection.

Taking Indease 400mg Capsule with cholesterol-lowering medicines called statins may cause severe muscle pain and weakness. Consult the doctor if you experience severe muscle pain or weakness.

Indease 400mg Capsule may cause kidney stones. Therefore, drink plenty of fluids while on treatment with Indease 400mg Capsule as it helps reduce the chances of forming a kidney stone. Consult the doctor if you develop kidney pain (middle to the lower stomach or back pain) or blood in the urine.

Indease 400mg Capsule does not reduce the risk of passing HIV to others through blood contamination or sexual contact. Therefore, practice safe sex to prevent the risk of transmission.

Consult the doctor before taking sildenafil, tadalafil, or vardenafil with Indease 400mg Capsule as taking them together might increase the risk of side effects like low blood pressure, penile erection lasting more than 4 hours, or visual changes associated with sildenafil, tadalafil, and vardenafil. Seek immediate medical assistance if you have an erection lasting longer than 4 hours.

Didanosine can be taken with Indease 400mg Capsule if prescribed by the doctor. However, maintain a gap of 1 hour between didanosine and Indease 400mg Capsule.

Indease 400mg Capsule may cause hyperglycaemia (high blood sugar) even though you do not have diabetes. Consult the doctor immediately if you notice symptoms of high blood sugar, like frequent urination, extreme thirst, blurred vision, extreme hunger, or weakness. High blood sugar can lead to a serious condition called ketoacidosis if not treated. Symptoms of ketoacidosis include nausea, vomiting, dry mouth, shortness of breath, and decreased consciousness.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Consult your doctor

It is not known whether Indease 400mg Capsule interacts with alcohol. Please consult your doctor for more information.

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Pregnancy

Caution

Indease 400mg Capsule belongs to pregnancy category C. It should be used during pregnancy only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Indease 400mg Capsule. HIV-positive women must not breastfeed as HIV infection can be passed to the baby in breast milk.

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Driving

Consult your doctor

It is not known if Indease 400mg Capsule affects your ability to drive. Drive or operate machinery only if you are feeling well.

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Liver

Caution

Please consult your doctor if you have liver problems, particularly if you have mild or moderate liver disease caused by cirrhosis.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Consult your doctor

Please consult the doctor. Your doctor may prescribe a suitable dose based on your child's age and condition.

Product Substitutes

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/020685s073lbl.pdf
  2. https://medlineplus.gov/druginfo/meds/a696028.html

About Indease 400mg Capsule

Indease 400mg Capsule belongs to a group of antiretroviral medicines indicated for the treatment of HIV infection. Indease 400mg Capsule does not cure HIV infection. It reduces the viral load in the body and keeps it at a low level. Taking Indease 400mg Capsule decreases the chance of developing AIDS (acquired immunodeficiency syndrome) and HIV-related illnesses such as cancer or serious infections.
 
Indease 400mg Capsule contains Indinavir, which works by decreasing the amount of HIV in the blood. It also increases the count of CD4 (T) cells, a type of white blood cell that helps the body fight infection.
 
In some cases, Indease 400mg Capsule may cause side effects such as nausea, headache, loss of appetite, and weakness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.
 
Consult the doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding whilst on treatment with Indease 400mg Capsule. Tell the doctor about your new or worsening symptoms during treatment with Indease 400mg Capsule. Keep your doctor informed about your health condition and medications to prevent any side effects/interactions.

Uses of Indease 400mg Capsule

HIV infection

Medicinal Benefits Mweb

Medicinal Benefits

Indease 400mg Capsule belongs to a group of antiretroviral medicines called protease inhibitors used to treat HIV infection. Indease 400mg Capsule contains Indinavir, which works by decreasing the amount of HIV in the blood. It also increases the count of CD4 (T) cells, a type of white blood cell that helps the body fight infection. Indease 400mg Capsule reduces the viral load in the body and keeps it at a low level. Taking Indease 400mg Capsule decreases the chance of developing AIDS (acquired immunodeficiency syndrome) and HIV-related illnesses such as cancer or serious infections. Indease 400mg Capsule may also be used in combination with other medicines to treat people exposed to HIV infection after accidental contact with HIV-contaminated blood, body fluids, or tissues.

Directions for Use

Swallow Indease 400mg Capsule as a whole with water or other beverages such as skim or non-fat milk, juice, coffee, or tea; do not chew or crush it. Take Indease 400mg Capsule on an empty stomach, i.e., 1 hour before or 2 hours after meals. If you experience stomach upset, take it with a light meal such as cornflakes or dry toast.

Side Effects of Indease 400mg Capsule

  • Headache
  • Dizziness
  • Loss of appetite
  • Nausea
  • Weakness 

Drug Warnings

Do not take Indease 400mg Capsule if you are allergic to any of its components. Inform your doctor if you have liver problems, especially if you have mild/moderate liver disease caused by cirrhosis, kidney problems, diabetes, haemophilia (a disorder in which the blood does not clot properly), high cholesterol and if you are taking cholesterol-lowering medicines known as statins. Let the doctor know if you are taking prescription/non-prescription medicines, including herbal products or dietary supplements.

Drug-Drug Interactions

verifiedApollotooltip
IndinavirAmiodarone
Critical
IndinavirSildenafil
Critical

Drug-Drug Interactions

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IndinavirAmiodarone
Critical
How does the drug interact with Indease 400mg Capsule:
The combination of Amiodarone and Indease 400mg Capsule may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Despite the fact that Amiodarone and Indease 400mg Capsule interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
IndinavirSildenafil
Critical
How does the drug interact with Indease 400mg Capsule:
Coadministration of Indease 400mg Capsule and Sildenafil can increase the blood levels and side effects of sildenafil.

How to manage the interaction:
Taking Indease 400mg Capsule and Sildenafil together is avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
IndinavirTolvaptan
Critical
How does the drug interact with Indease 400mg Capsule:
When Tolvaptan and Indease 400mg Capsule are taken together, may significantly increase the blood levels and effects of Tolvaptan.

How to manage the interaction:
There may be a possibility of interaction between Tolvaptan and Indease 400mg Capsule, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
IndinavirNimodipine
Critical
How does the drug interact with Indease 400mg Capsule:
When Nimodipine is taken with Indease 400mg Capsule, it can increase the risk of side effects.

How to manage the interaction:
Taking Nimodipine with Indease 400mg Capsule is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience irregular heart rhythm, swelling. Do not discontinue any medications without a doctor's advice.
IndinavirSimvastatin
Critical
How does the drug interact with Indease 400mg Capsule:
Combining Indease 400mg Capsule and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Indease 400mg Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
IndinavirSilodosin
Critical
How does the drug interact with Indease 400mg Capsule:
Coadministration of Silodosin with Indease 400mg Capsule may significantly increase the blood levels and effects of Silodosin, this may cause blood pressure to fall excessively and heart rate to increase, especially when you rise from a sitting or lying position.

How to manage the interaction:
Taking Silodosin with Indease 400mg Capsule together is not recommended s it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not discontinue any medications without consulting a doctor.
IndinavirAlprazolam
Critical
How does the drug interact with Indease 400mg Capsule:
The combination of Alprazolam and Indease 400mg Capsule may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Alprazolam and Indease 400mg Capsule, it can be used if prescribed by a doctor. Consult a doctor if you have drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
IndinavirLurasidone
Critical
How does the drug interact with Indease 400mg Capsule:
Using Lurasidone together with Indease 400mg Capsule may result in significantly higher Lurasidone blood levels. This may increase the possibility of negative effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)

How to manage the interaction:
While Lurasidone and Indease 400mg Capsule may interact, they can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
IndinavirTicagrelor
Critical
How does the drug interact with Indease 400mg Capsule:
Using ticagrelor together with Indease 400mg Capsule can cause risk of bleeding.

How to manage the interaction:
Taking Ticagrelor with Indease 400mg Capsule is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
IndinavirMidazolam
Critical
How does the drug interact with Indease 400mg Capsule:
Indease 400mg Capsule and Midazolam co-administration may considerably enhance Midazolam blood levels and effects.

How to manage the interaction:
Although taking Indease 400mg Capsule and Midazolam together may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • MIDAZOLAM
  • TRIAZOLAM
  • ALPRAZOLAM
  • PIMOZIDE
  • CISAPRIDE
  • AMIODARONE
  • ASTEMIZOLE
  • SILDENAFIL
  • ALFUZOSIN
  • RIFAMPIN
  • LOVASTATIN
  • SIMVASTATIN
  • ROSUVASTATIN
  • ATORVASTATIN
  • ATAZANAVIR
  • St John's wort

Habit Forming

No

Special Advise

  • Avoid taking Indease 400mg Capsule at the same time as meals that are high in calories, protein, or fat.
  • Drink at least 1.5 litres of fluids (preferably water) throughout the day, every day. 

Diet & Lifestyle Advise

  • Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
  • Never share personal items that can have body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injections or drug equipment.
  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with family or doing whatever makes you happy.

Indease 400mg Capsule Substitute

Always consult your doctor before taking any new medications and supplements

  • Inbec 400 Capsule 1'S

    by Others

    ₹4782.70per tablet
    ›

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