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Drug-Drug Interactions
Critical
Critical
Drug-Drug Interactions
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Critical
How does the drug interact with Intedex Injection:
Co-administration of Desmopressin with Intedex Injection may increase the risk of hyponatremia (low levels of salt in the blood).
How to manage the interaction:
Co-administration of Intedex Injection and Desmopressin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Desmopressin with Intedex Injection may increase the risk of hyponatremia (low levels of salt in the blood).
How to manage the interaction:
Co-administration of Intedex Injection and Desmopressin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Critical
How does the drug interact with Intedex Injection:
When Intedex Injection is taken with Ranolazine, may significantly reduce the blood levels of Ranolazine.
How to manage the interaction:
Co-administration of Ranolazine and Intedex Injection can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
When Intedex Injection is taken with Ranolazine, may significantly reduce the blood levels of Ranolazine.
How to manage the interaction:
Co-administration of Ranolazine and Intedex Injection can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
Critical
How does the drug interact with Intedex Injection:
When Regorafenib is taken with Intedex Injection, may significantly reduce the blood levels of Regorafenib.
How to manage the interaction:
Co-administration of Regorafenib and Intedex Injection can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
When Regorafenib is taken with Intedex Injection, may significantly reduce the blood levels of Regorafenib.
How to manage the interaction:
Co-administration of Regorafenib and Intedex Injection can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
DexamethasoneRilpivirine
Critical
How does the drug interact with Intedex Injection:
When Rilpivirine is taken with Intedex Injection, may significantly reduce the blood levels of Rilpivirine.
How to manage the interaction:
Co-administration of Rilpivirine and Intedex Injection can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
When Rilpivirine is taken with Intedex Injection, may significantly reduce the blood levels of Rilpivirine.
How to manage the interaction:
Co-administration of Rilpivirine and Intedex Injection can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Intedex Injection:
Co-administration of Norfloxacin with Intedex Injection can increase the risk or severity of tendinitis (inflammation of the tendons attached to the muscle and bones).
How to manage the interaction:
Taking Norfloxacin with Intedex Injection together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience Stiff joints or difficulty moving your joints, joint pains, Swelling, or skin discoloration, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Co-administration of Norfloxacin with Intedex Injection can increase the risk or severity of tendinitis (inflammation of the tendons attached to the muscle and bones).
How to manage the interaction:
Taking Norfloxacin with Intedex Injection together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience Stiff joints or difficulty moving your joints, joint pains, Swelling, or skin discoloration, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Intedex Injection:
Taking Intedex Injection with Deflazacort may significantly reduce the blood levels of deflazacort, which may make the medication less effective in treating the condition.
How to manage the interaction:
Although using Intedex Injection and Deflazacort together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.
Taking Intedex Injection with Deflazacort may significantly reduce the blood levels of deflazacort, which may make the medication less effective in treating the condition.
How to manage the interaction:
Although using Intedex Injection and Deflazacort together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.
Severe
How does the drug interact with Intedex Injection:
When Intedex Injection is taken with Infliximab, it can increase the risk or severity of developing serious infections.
How to manage the interaction:
Taking Infliximab with Intedex Injection together can result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee. Do not stop using any medications without a doctor's advice.
When Intedex Injection is taken with Infliximab, it can increase the risk or severity of developing serious infections.
How to manage the interaction:
Taking Infliximab with Intedex Injection together can result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Intedex Injection:
Taking Intedex Injection may reduce the blood levels of Dasatinib, making the medication less effective in treating the condition.
How to manage the interaction:
Although there is a possible interaction, Intedex Injection can be taken with Dasatinib if prescribed by the doctor. In case of any unusual side effects, consult a doctor. Do not discontinue the medication without consulting a doctor.
Taking Intedex Injection may reduce the blood levels of Dasatinib, making the medication less effective in treating the condition.
How to manage the interaction:
Although there is a possible interaction, Intedex Injection can be taken with Dasatinib if prescribed by the doctor. In case of any unusual side effects, consult a doctor. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Intedex Injection:
Co-administration of Intedex Injection with Caspofungin may cause Caspofungin to be less effective.
How to manage the interaction:
Although there is a possible interaction between Caspofungin and Intedex Injection, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
Co-administration of Intedex Injection with Caspofungin may cause Caspofungin to be less effective.
How to manage the interaction:
Although there is a possible interaction between Caspofungin and Intedex Injection, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Intedex Injection:
Co-administration of Intedex Injection together with Olaparib can reduce the blood levels of Olaparib.
How to manage the interaction:
Although taking Olaparib and Intedex Injection together can evidently cause an interaction, it can be taken if a doctor has suggested it. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
Co-administration of Intedex Injection together with Olaparib can reduce the blood levels of Olaparib.
How to manage the interaction:
Although taking Olaparib and Intedex Injection together can evidently cause an interaction, it can be taken if a doctor has suggested it. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
DEXAMETHASONE-8MGCaffeine containing foods/drinks
Moderate
Drug-Food Interactions
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DEXAMETHASONE-8MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu
How to manage the interaction:
Taking Intedex Injection with Caffeine may increase the side effects of Intedex Injection. Avoid consuming caffeine while taking Intedex Injection.
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu
How to manage the interaction:
Taking Intedex Injection with Caffeine may increase the side effects of Intedex Injection. Avoid consuming caffeine while taking Intedex Injection.
Drug-Diseases Interactions
DEXAMETHASONE-8MGOther and unspecified infectious diseases
Severe
DEXAMETHASONE-8MGDisorders related to short gestation and low birth weight, not elsewhere classified
Severe
Drug-Diseases Interactions
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DEXAMETHASONE-8MGOther and unspecified infectious diseases
Severe
How does the disease interact with Intedex Injection:
Corticosteroids' immunosuppressive and anti-inflammatory properties, especially when used in larger doses, have the potential to reduce host resistance to pathogens, impair the capacity to localise infections, and disguise infection-related symptoms. Perhaps secondary infections are more prone to occur. In general, corticosteroids should not be administered to patients with active infections, particularly systemic fungal infections, unless absolutely essential for medical reasons and after effective antimicrobial medication or another suitable course of treatment has been started.
How to manage the interaction:
Corticosteroids, particularly in higher dosages, may decrease host resistance to infectious agents, decrease the ability to localize infections, and mask the symptoms of infection.
Corticosteroids' immunosuppressive and anti-inflammatory properties, especially when used in larger doses, have the potential to reduce host resistance to pathogens, impair the capacity to localise infections, and disguise infection-related symptoms. Perhaps secondary infections are more prone to occur. In general, corticosteroids should not be administered to patients with active infections, particularly systemic fungal infections, unless absolutely essential for medical reasons and after effective antimicrobial medication or another suitable course of treatment has been started.
How to manage the interaction:
Corticosteroids, particularly in higher dosages, may decrease host resistance to infectious agents, decrease the ability to localize infections, and mask the symptoms of infection.
DEXAMETHASONE-8MGDisorders related to short gestation and low birth weight, not elsewhere classified
Severe
How does the disease interact with Intedex Injection:
Manufacturers of the drugs believe that using some parenteral formulations of Intedex Injection, hydrocortisone, methylprednisolone, prednisolone, and triamcinolone in neonates, especially preterm newborns and infants with low birth weight, is contraindicated.
How to manage the interaction:
The use of certain parenteral formulations of Intedex Injection is contraindicated in neonates, particularly premature infants and infants of low birth weight.
Manufacturers of the drugs believe that using some parenteral formulations of Intedex Injection, hydrocortisone, methylprednisolone, prednisolone, and triamcinolone in neonates, especially preterm newborns and infants with low birth weight, is contraindicated.
How to manage the interaction:
The use of certain parenteral formulations of Intedex Injection is contraindicated in neonates, particularly premature infants and infants of low birth weight.
DEXAMETHASONE-8MGFibrosis and cirrhosis of liver
Moderate
How does the disease interact with Intedex Injection:
Due to cirrhosis patients' lower metabolism, corticosteroids may have stronger effects on them. Patients with cirrhosis need to have their cortisol levels constantly checked. For certain people, dosage modifications may be necessary.
How to manage the interaction:
Patients with cirrhosis should be monitored more closely for excessive cortisol effects.
Due to cirrhosis patients' lower metabolism, corticosteroids may have stronger effects on them. Patients with cirrhosis need to have their cortisol levels constantly checked. For certain people, dosage modifications may be necessary.
How to manage the interaction:
Patients with cirrhosis should be monitored more closely for excessive cortisol effects.
DEXAMETHASONE-8MGOther mental disorders due to brain damage and dysfunction and to physical disease
Moderate
How does the disease interact with Intedex Injection:
Psychotic and emotional instability symptoms may be made worse by corticosteroids. During corticosteroid medication, patients with these disorders should be monitored for any worsening or intensification of their symptoms.
How to manage the interaction:
Patients with psychosis and emotional instability should be monitored for increased or worsened symptoms during corticosteroid therapy.
Psychotic and emotional instability symptoms may be made worse by corticosteroids. During corticosteroid medication, patients with these disorders should be monitored for any worsening or intensification of their symptoms.
How to manage the interaction:
Patients with psychosis and emotional instability should be monitored for increased or worsened symptoms during corticosteroid therapy.
DEXAMETHASONE-8MGUnspecified diabetes mellitus
Moderate
How does the disease interact with Intedex Injection:
By opposing the effect of insulin and inhibiting its production, corticosteroids can increase blood sugar levels. This inhibits peripheral glucose absorption and increases gluconeogenesis. Patients with diabetes mellitus, glucose intolerance, or a tendency for hyperglycemia should receive corticosteroid therapy with caution. During corticosteroid medication, patients with diabetes mellitus should be evaluated more carefully, and their anti-diabetic regimen should be changed correspondingly.
How to manage the interaction:
Patients with diabetes mellitus should be monitored more closely during corticosteroid therapy, and their antidiabetic regimen adjusted accordingly.
By opposing the effect of insulin and inhibiting its production, corticosteroids can increase blood sugar levels. This inhibits peripheral glucose absorption and increases gluconeogenesis. Patients with diabetes mellitus, glucose intolerance, or a tendency for hyperglycemia should receive corticosteroid therapy with caution. During corticosteroid medication, patients with diabetes mellitus should be evaluated more carefully, and their anti-diabetic regimen should be changed correspondingly.
How to manage the interaction:
Patients with diabetes mellitus should be monitored more closely during corticosteroid therapy, and their antidiabetic regimen adjusted accordingly.
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