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  1. Home
  2. Medicine

  3. Isavufic 200 mg Injection 1's

Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
Know More
COD available

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Isavufic 200 mg Injection 1's, Pack of 1 INJECTION
Isavufic 200 mg Injection 1's, Pack of 1 INJECTION
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Whats That

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Composition :

ISAVUCONAZOLE-200MG

Manufacturer/Marketer :

Gufic Bioscience Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIFUNGALS

Country of origin

India

Manufacturer/Marketer address

Shantisadan, Mirzapur Road, Ahmedabad -380001
Other Info - ISA0029

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 20, 2024 | 1:15 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Isavufic 200 mg Injection contains Isavuconazole which works by inhibiting the synthesis of fungal cell membranes which are essential for their survival. Thereby, Isavufic 200 mg Injection kills or inhibits the growth of the fungus.

Mucormycosis is not contagious. Mucormycosis is a severe fungal infection of the skin or respiratory system that occurs in people with a weakened immune system.

Isavufic 200 mg Injection may cause headaches as a common side effect. However, if the condition persists or worsens, please consult a doctor.

You are not recommended to take Isavufic 200 mg Injection with ketoconazole as it may increase the levels of Isavufic 200 mg Injection in your blood and increase the risk of side effects such as diarrhoea, vomiting, nausea or liver problems. However, please consult your doctor before taking Isavufic 200 mg Injection with other medicines.

Isavufic 200 mg Injection should be used with caution in patients with liver problems as Isavufic 200 mg Injection may increase liver enzymes. Thus, monitoring of liver enzymes is advised while taking Isavufic 200 mg Injection. However, you are recommended to inform your doctor if you have any liver problems.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Isavufic 200 mg Injection as it may increase the risk of liver damage.

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Pregnancy

Consult your doctor

Isavufic 200 mg Injection is not recommended during pregnancy except in patients with severe or potentially life-threatening fungal infections in whom Isavufic 200 mg Injection may be used if the doctor thinks the benefits outweigh the risks. Therefore, please inform your doctor if you are pregnant or planning pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Isavufic 200 mg Injection. Please inform your doctor if you are breastfeeding.

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Driving

Caution

Drive only if you are alert after taking Isavufic 200 mg Injection as it may cause drowsiness, confusion or dizziness.

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Liver

Caution

Inform your doctor if you have liver problems before receiving Isavufic 200 mg Injection as may worsen your condition. Your doctor may adjust the dose as required based on your condition.

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Kidney

Caution

The use of Isavufic 200 mg Injection in patients with severe Kidney impairment is not established. Inform your doctor if you have kidney problems before receiving Isavufic 200 mg Injection as may worsen your condition. Your doctor may adjust the dose as required based on your condition.

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Children

Unsafe

Isavufic 200 mg Injection is not recommended for children below 18 years as the safety and effectiveness were not established.

Product Substitutes

Reference

  1. https://www.medicines.org.uk/emc/files/pil.5069.pdf
  2. https://www.ema.europa.eu/en/documents/product-information/cresemba-epar-product-information_en.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/207500orig1s000lbl.pdf

About Isavufic 200 mg Injection

Isavufic 200 mg Injection belongs to the class of medicines called antifungals used to treat fungal infections such as invasive aspergillosis and mucormycosis (in patients for whom Amphotericin B is not suitable). Invasive aspergillosis is an infection caused by Aspergillus fungus. It occurs by breathing and spreads from the lungs to the kidneys, brain, heart or skin. Mucormycosis is a rare but serious fungal infection of the skin or respiratory system that occurs in people with weakened immune systems.

Isavufic 200 mg Injection contains Isavuconazole which works by fungicidal actions by disrupting the biosynthesis of ergosterol,which are essential for their survival and kills fungus that causes infection.

Isavufic 200 mg Injection will be administered by a healthcare professional; do not self-administer. Some people may experience headache, decreased appetite, sleepiness, nausea, vomiting, stomach pain, diarrhoea or chest pain. Most of these side effects of Isavufic 200 mg Injection do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

If you are allergic to Isavufic 200 mg Injection or any other medicines, please tell your doctor. Isavufic 200 mg Injection is not recommended for children below 18 years as the safety and effectiveness were not established. If you are pregnant, it is advised to consult a doctor before using Isavufic 200 mg Injection. Avoid breastfeeding while taking Isavufic 200 mg Injection. Drive only if you are alert after taking Isavufic 200 mg Injection as it may cause drowsiness, confusion or dizziness. Avoid alcohol consumption while taking Isavufic 200 mg Injection as it may increase the risk of liver damage.

Uses of Isavufic 200 mg Injection

Invasive aspergillosis and Mucormycosis

Medicinal Benefits Mweb

Medicinal Benefits

Isavufic 200 mg Injection contains Isavuconazole, a broad-spectrum antifungal that is effective against a wide variety of microorganisms. It inhibits the synthesis of fungal cell membranes that are essential for their survival. Thereby, Isavufic 200 mg Injection kills or stops the growth of the fungus.

Directions for Use

Isavufic 200 mg Injection will be administered by a healthcare professional; do not self-administer.

Side Effects of Isavufic 200 mg Injection

  • Headache
  • Decreased appetite
  • Sleepiness
  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Chest pain

Drug Warnings

If you are allergic to Isavufic 200 mg Injection or any other medicines, please tell your doctor. Isavufic 200 mg Injection is not recommended for children below 18 years as the safety and effectiveness were not established. If you are pregnant, it is advised to consult a doctor before using Isavufic 200 mg Injection. Avoid breastfeeding while taking Isavufic 200 mg Injection. Drive only if you are alert after taking Isavufic 200 mg Injection as it may cause drowsiness, confusion or dizziness. Avoid alcohol consumption while taking Isavufic 200 mg Injection as it may increase the risk of liver damage. If you experience severe blistering of the eyes, mouth, skin or genitals, seek immediate medical help.

Drug-Drug Interactions

verifiedApollotooltip
IsavuconazoleSaquinavir
Critical
IsavuconazoleCisapride
Critical

Drug-Drug Interactions

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IsavuconazoleSaquinavir
Critical
How does the drug interact with Isavufic 200 mg Injection:
When Isavufic 200 mg Injection is taken with Saquinavir, it can increase the risk of liver damage.

How to manage the interaction:
Taking Isavufic 200 mg Injection with Saquinavir is not recommended, it can be taken if prescribed by the doctor. However, if you experience symptoms like nausea, vomiting, diarrhea while on therapy with these drugs, consult the doctor.
IsavuconazoleCisapride
Critical
How does the drug interact with Isavufic 200 mg Injection:
When Isavufic 200 mg Injection is taken with Cisapride, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Isavufic 200 mg Injection with Cisapride is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
IsavuconazoleCeritinib
Critical
How does the drug interact with Isavufic 200 mg Injection:
Taking ceritinib with Isavufic 200 mg Injection may significantly increase the blood levels of Isavufic 200 mg Injection.

How to manage the interaction:
Taking Isavufic 200 mg Injection with Ceritinib is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loose stools, yellow discoloration of skin and eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
IsavuconazoleRitonavir
Critical
How does the drug interact with Isavufic 200 mg Injection:
Taking Isavufic 200 mg Injection with Ritonavir may significantly increase the blood levels of Isavufic 200 mg Injection, which may increase the risk of side effects.

How to manage the interaction:
Taking Isavufic 200 mg Injection with Ritonavir is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like nausea, vomiting, loose stools, light color stools or dark urine, consult a doctor. Do not discontinue any medications without consulting a doctor.
IsavuconazolePhenytoin
Critical
How does the drug interact with Isavufic 200 mg Injection:
Co-administration of phenytoin and Isavufic 200 mg Injection may significantly reduce the blood levels of Isavufic 200 mg Injection, which may make Isavufic 200 mg Injection less effective in treating your condition.

How to manage the interaction:
Taking Isavufic 200 mg Injection with Phenytoin is not recommended as it can cause an interaction, consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
IsavuconazoleKetoconazole
Critical
How does the drug interact with Isavufic 200 mg Injection:
Co-administration of Ketoconazole and Isavufic 200 mg Injection can significantly increase the blood levels of Isavufic 200 mg Injection, which may increase the risk of side effects.

How to manage the interaction:
Taking Isavufic 200 mg Injection with Ketoconazole is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience symptoms like nausea, stomach pain, headache while on therapy with these drugs, consult the doctor. Do not discontinue any medication without consulting a doctor.
IsavuconazoleItraconazole
Critical
How does the drug interact with Isavufic 200 mg Injection:
The blood levels and effects of Isavufic 200 mg Injection may be significantly enhanced by taking Itraconazole along with it.

How to manage the interaction:
Co-administration of Isavufic 200 mg Injection and Itraconazole can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
IsavuconazolePhenobarbital
Critical
How does the drug interact with Isavufic 200 mg Injection:
When Isavufic 200 mg Injection is taken with Phenobarbital, may decrease the blood levels of Isavufic 200 mg Injection, which may make Isavufic 200 mg Injection less effective.

How to manage the interaction:
Taking Isavufic 200 mg Injection with Phenobarbital is not recommended it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
IsavuconazolePosaconazole
Critical
How does the drug interact with Isavufic 200 mg Injection:
When Isavufic 200 mg Injection is taken with Posaconazole, it can increase the levels of Isavufic 200 mg Injection in the blood.

How to manage the interaction:
Although there is an interaction between Isavufic 200 mg Injection and posaconazole, it can be taken if prescribed by the doctor. However, if you experience nausea, vomiting, diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
IsavuconazolePrimidone
Critical
How does the drug interact with Isavufic 200 mg Injection:
Taking Isavufic 200 mg Injection with primidone may decrease the blood levels of Isavufic 200 mg Injection and reduce its effectiveness.

How to manage the interaction:
Taking Isavufic 200 mg Injection with primidone is not recommended, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • RITONAVIR
  • EFAVIRENZ
  • ETRAVIRINE
  • RIFABUTIN
  • RIFAMPICIN
  • PREDNISONE
  • TACROLIMUS
  • SIROLIMUS
  • CICLOSPORIN
  • PIOGLITAZONE
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • PHENYTOIN
  • KETOCONAZOLE
  • METFORMIN

Habit Forming

No

Special Advise

Regular blood tests are recommended while taking Isavufic 200 mg Injection to monitor liver functioning.

Diet & Lifestyle Advise

  • Try to avoid areas with a lot of dust like excavation or construction sites. If you can’t avoid it, wear an N95 mask while going to such places.
  • Clean skin injuries with soap and water, especially if they have been exposed to dust or soil to decrease the chances of developing a skin infection.
  • Bandage all wounds until they heal to prevent fungal infections.
  • Wash your hands frequently and keep your hands clean to prevent the spread of germs.
  • Avoid dusty activities and digging in the soil.
  • Wear shoes, a long-sleeved t-shirt, long pants and a mask while doing outdoor activities such as yard work, gardening or vising wooded areas to protect from fungus commonly present in the environment.
  • Maintain a diet that is low in sugar, refined carbohydrates, mould-containing foods and yeast.

Isavufic 200 mg Injection Substitute

Always consult your doctor before taking any new medications and supplements

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