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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

SERTRALINE-50MG

Manufacturer/Marketer :

Jasish Healthcare Llp

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIDEPRESSANT

Country of origin

India
Other Info - IST0037

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Istralin-50 Tablet contains Sertraline, which inhibits the reabsorption of released serotonin back into the nerve cells. Thus, it increases the serotonin (chemical messenger) activity in the brain that regulates mood, behaviour and emotions. Thereby, Istralin-50 Tablet helps in relieving depression, lightening the mood and relieving anxiety symptoms such as fear and panic.

Yes, Istralin-50 Tablet may be used to treat a panic disorder by reducing fear. However, please consult a doctor before using the Istralin-50 Tablet .

No, you are not recommended to take Istralin-50 Tablet with opioids as co-administration of these medicines may cause adverse effects such as hallucinations, increased muscle tension, excessive sweating, fever, anxiety, involuntary, rhythmic contractions of muscles, including the muscles that control eye movement, tremor or even coma. However, before using Istralin-50 Tablet with any other medicines, you are advised to contact your doctor so that the dosage may be adjusted accordingly to use safely.

Yes, Istralin-50 Tablet may cause self-harming or suicidal thoughts, especially in patients aged less than 25 years or who have a history of self-harming thoughts. Therefore, please consult a doctor immediately if you experience any such thoughts while taking Istralin-50 Tablet .

It takes about 2 weeks or longer, usually for Istralin-50 Tablet to work. However, it is recommended to use Istralin-50 Tablet for as long as your doctor has prescribed it for you.

Istralin-50 Tablet may affect male fertility as it may reduce sperm quality. Therefore, please consult a doctor if you are planning to father a child.

Istralin-50 Tablet should be used with caution in diabetic patients as it may alter blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Istralin-50 Tablet , especially if you have diabetes, and the dose of diabetic medicines may be adjusted appropriately by your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid consumption of alcohol with Istralin-50 Tablet as it may increase the risk of drowsiness, dizziness or difficulty in concentrating.

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Pregnancy

Unsafe

Istralin-50 Tablet is a Category C pregnancy drug and is not recommended for use during pregnancy especially in the last 3 months as it may cause a serious condition in the baby such as persistent pulmonary hypertension of the newborn (PPHN) which causes the baby to appear bluish and makes breathing faster. Therefore, please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Istralin-50 Tablet may be excreted in human milk. Please consult a doctor if you are a breastfeeding mother. Istralin-50 Tablet is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Unsafe

Istralin-50 Tablet may cause dizziness, drowsiness or impair thinking. Therefore, avoid driving if you experience any of these symptoms after taking Istralin-50 Tablet .

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Liver

Caution

Take Istralin-50 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

If you have any concerns regarding the use of Istralin-50 Tablet in patients with kidney problems, please consult a doctor.

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Children

Caution

Istralin-50 Tablet may be used only to treat Obsessive-compulsive disorder (OCD) in children aged 6 to 17 years. Istralin-50 Tablet is not recommended to treat any other disorders in children below 18 years of age.

About Istralin-50 Tablet

Istralin-50 Tablet belongs to a class of antidepressant drugs called selective serotonin reuptake inhibitors (SSRIs) used in the treatment of depression, post-traumatic stress disorder (PTSD), social anxiety disorder, panic disorder and obsessive-compulsive disorder (OCD). Depression is a mood disorder associated with symptoms such as sadness, unable to sleep properly or enjoy life as you used to do. OCD is a mental disorder with symptoms such as excessive thoughts or ideas (obsessions), leading to repetitive behaviours (compulsions). Panic disorder is linked to anxiety with sudden feelings of fear when there is no danger in reality. PTSD is a mental condition that occurs after experiencing a very emotional or terrifying event and has symptoms similar to anxiety and depression. Social anxiety disorder (social phobia) is associated with intense anxiety or distress in social situations.

Istralin-50 Tablet contains Sertraline that works by inhibiting the reabsorption of released serotonin back into the nerve cells. Thus, it increases serotonin activity (chemical messenger) in the brain that is involved in regulating mood, behaviour, and emotions. Thereby, Istralin-50 Tablet helps relieve depression, lighten the mood and relieve anxiety symptoms such as fear and panic.

Take Istralin-50 Tablet with or without food as prescribed by your doctor and swallow whole with a glass of water. Do not break, crush or chew it. Your doctor will advise you how often you take Istralin-50 Tablet based on your medical condition. Some people may experience drowsiness, dizziness, insomnia (difficulty in sleeping), dry mouth, nausea, headache, diarrhoea, tiredness or ejaculation failure. Most of these side effects of Istralin-50 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Istralin-50 Tablet or any other medicines, please tell your doctor. Istralin-50 Tablet may be used only to treat Obsessive-compulsive disorder (OCD) in children aged 6 to 17 years and not treat any other conditions in children below 18 years of age. Istralin-50 Tablet is not recommended for use during pregnancy, especially in the last 3 months. It may cause a serious condition in the baby, such as persistent pulmonary hypertension of the newborn (PPHN), which causes the baby to appear bluish and breathing faster. Therefore, please consult a doctor if you are pregnant or planning for pregnancy. Istralin-50 Tablet may be excreted in human milk. Please consult a doctor if you are a breastfeeding mother. Istralin-50 Tablet should be used with caution in elderly patients as there is an increased risk of low sodium levels in the blood.  If you have any self-harming or suicidal thoughts before taking Istralin-50 Tablet , inform your doctor as they may worsen in the initial days of taking Istralin-50 Tablet . Do not take Istralin-50 Tablet with monoamine oxidase inhibitors (MAOIs) such as moclobemide and methylene blue to treat depression and opioids as it may cause severe adverse effects.

Uses of Istralin-50 Tablet

Depression, Post-traumatic stress disorder (PTSD), Social anxiety disorder, Panic disorder, Obsessive-compulsive disorder (OCD).

Medicinal Benefits Mweb

Medicinal Benefits

Istralin-50 Tablet contains Sertraline, an antidepressant that inhibits the reabsorption of released serotonin back into the nerve cells. Thus, it increases serotonin activity (chemical messenger) in the brain that is involved in regulating mood, behaviour, and emotions. Thereby, Istralin-50 Tablet helps relieve depression, lighten the mood and relieve anxiety symptoms such as fear and panic.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Oral solution: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dropper.

Side Effects of Istralin-50 Tablet

  • Drowsiness
  • Dizziness
  • Insomnia (sleeplessness)
  • Dry mouth
  • Nausea
  • Headache
  • Diarrhoea
  • Tiredness
  • Ejaculation failure

Drug Warnings

If you are allergic to Istralin-50 Tablet or any other medicines, please tell your doctor. Istralin-50 Tablet may be used only to treat Obsessive-compulsive disorder (OCD) in children aged 6 to 17 years and does not treat any other conditions in children below 18 years of age. Istralin-50 Tablet is not recommended for use during pregnancy, especially in the last 3 months. It may cause a serious condition in the baby, such as persistent pulmonary hypertension of the newborn (PPHN), which causes the baby to appear bluish and breathing faster. Therefore, please consult a doctor if you are pregnant or planning for pregnancy. Istralin-50 Tablet may be excreted in human milk. Please consult a doctor if you are a breastfeeding mother. Istralin-50 Tablet should be used with caution in elderly patients as there is an increased risk of low sodium levels in the blood.  If you have any self-harming or suicidal thoughts before taking Istralin-50 Tablet , inform your doctor as they may worsen in the initial days of taking Istralin-50 Tablet . Do not take Istralin-50 Tablet with monoamine oxidase inhibitors (MAOIs) such as moclobemide and methylene blue to treat depression and opioids pain killer as it may cause severe adverse effects. If you have diabetes, fits, bipolar disorder, bleeding disorders, glaucoma, severe diarrhoea, low sodium or potassium levels in the blood, neuroleptic malignant syndrome or serotonin syndrome (potentially life-threatening conditions), liver or heart problems, inform your doctor before taking Istralin-50 Tablet . 

Drug-Drug Interactions

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SertralineEliglustat
Critical
SertralinePimozide
Critical

Drug-Drug Interactions

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SertralineEliglustat
Critical
How does the drug interact with Istralin-50 Tablet:
Coadministration of Eliglustat and Istralin-50 Tablet may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is an interaction between Eliglustat and Istralin-50 Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
SertralinePimozide
Critical
How does the drug interact with Istralin-50 Tablet:
Taking Istralin-50 Tablet with pimozide can increase the risk of heart rhythm problems.

How to manage the interaction:
There may be a possibility of interaction between Pimozide and Istralin-50 Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs -dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations-call a doctor right away. Do not stop using any medications without a doctor's advice.
SertralineZiprasidone
Critical
How does the drug interact with Istralin-50 Tablet:
Co-administration of Istralin-50 Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Istralin-50 Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
SertralineSelegiline
Critical
How does the drug interact with Istralin-50 Tablet:
Co-administration of Istralin-50 Tablet with Selegiline can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Selegiline with Istralin-50 Tablet together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
SertralineHalofantrine
Critical
How does the drug interact with Istralin-50 Tablet:
Coadministration of halofantrine and Istralin-50 Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Istralin-50 Tablet and halofantrine, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
SertralineIsocarboxazid
Critical
How does the drug interact with Istralin-50 Tablet:
Co-administration of Istralin-50 Tablet with Isocarboxazid can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Isocarboxazid with Istralin-50 Tablet there may be a possibility of interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
SertralineProcarbazine
Critical
How does the drug interact with Istralin-50 Tablet:
When Procarbazine is taken with Istralin-50 Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Istralin-50 Tablet and Procarbazine, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
SertralineDronedarone
Critical
How does the drug interact with Istralin-50 Tablet:
Co-administration of Dronedarone and Istralin-50 Tablet may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Dronedarone with Istralin-50 Tablet is not recommend, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
SertralineTranylcypromine
Critical
How does the drug interact with Istralin-50 Tablet:
Taking Tranylcypromine and Istralin-50 Tablet may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine and Istralin-50 Tablet is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, and diarrhoea-contact a doctor right away. Do not stop using any medications without a doctor's advice.
SertralineThioridazine
Critical
How does the drug interact with Istralin-50 Tablet:
Co-administration of Thioridazine and Istralin-50 Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Thioridazine and Istralin-50 Tablet is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations -contact a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • SELEGILINE
  • LINEZOLID
  • PIMOZIDE
  • HALOPERIDOL
  • PERPHENAZINE
  • OLANZAPINE
  • BUPRENORPHINE
  • FENTANYL
  • TRAMADOL
  • NALOXONE
  • WARFARIN
  • TICLOPIDINE
  • MOCLOBEMIDE
  • METHYLENE BLUE
  • FLUCONAZOLE
  • POSACONAZOLE
  • VORICONAZOLE
  • KETOCONAZOLE
  • ITRACONAZOLE
  • ERYTHROMYCIN
  • TELITHROMYCIN
  • CLARITHROMYCIN
  • LEVOFLOXACIN
  • NEFAZODONE
  • FLUOXETINE
  • FLUVOXAMINE
  • AMITRIPTYLINE
  • NORTRIPTYLINE
  • DESIPRAMINE
  • LITHIUM
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • IBUPROFEN
  • ASPIRIN
  • TOLBUTAMIDE
  • CIMETIDINE
  • PANTOPRAZOLE
  • RABEPRAZOLE
  • OMEPRAZOLE
  • LANSOPRAZOLE
  • LEVOMEPROMAZINE

Habit Forming

No

Special Advise

  • Istralin-50 Tablet may interfere with a urine test. Therefore, it is advised to inform your doctor or lab technician that you are taking Istralin-50 Tablet .

Diet & Lifestyle Advise

  • Maintain a diet rich in fruits, vegetables and whole grains. Avoid fried foods, high-fat dairy products, pastries and processed foods as they may worsen anxiety. Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters.
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Regularly attend therapy sessions.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Avoid smoking and alcohol consumption.

Istralin-50 Tablet Substitute

Substitutes safety advice
  • Serta-50 Tablet 15's

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    12.99per tablet
  • Daxid 50 mg Tablet 15's

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    10.02per tablet
  • Zosert 50 Tablet 10's

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    11.88per tablet
  • Serlift 50 Tablet 10's

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    10.94per tablet
  • Sertima-50 Tablet 10's

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    11.39per tablet
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