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Author Details

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Composition :

SITAGLIPTIN-100MG

Manufacturer/Marketer :

Skymap Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Medicinal Benefits Mweb

Medicinal Benefits

Janumap 100 Tablet 7's work by blocking the action of DPP-4 (an enzyme which destroys the hormone ‘Incretin’). The enzyme ‘Incretins’ helps produce more insulin only when required and reduces blood sugar produced by the liver when not needed. Thus, Janumap 100 Tablet 7's plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer and delayed wound healing.

About Janumap 100 Tablet 7's

Janumap 100 Tablet 7's belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors used in treating type 2 diabetes in adults. Janumap 100 Tablet 7's is prescribed for the condition of type 2 diabetes when diet and exercise alone cannot control their blood sugar levels. It is the first-line therapy for patients with type 2 diabetes that restores the body's response to insulin. Insulin is the hormone that controls sugar levels in your blood. People with type 2 diabetes either do not produce enough insulin, or the insulin produced cannot perform its function in the body (insulin resistance). Middle-aged or older individuals are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes.

Janumap 100 Tablet 7's contains sitagliptin. Janumap 100 Tablet 7's work by blocking the action of DPP-4 (an enzyme which destroys the hormone 'Incretin'). The enzyme 'Incretins' helps produce more insulin only when required and reduces blood sugar produced by the liver when not needed.

Janumap 100 Tablet 7's should be taken with food or an empty stomach. However, it should be taken at the same time of the day each time for the best results. For better advice, your doctor will decide what dose should be taken, which can change quickly depending on your condition. The most common side effect of Janumap 100 Tablet 7's is hypoglycaemia (low blood glucose levels), upper respiratory tract infection, nasopharyngitis (infection of the nose and throat with common cold) and headache.

Janumap 100 Tablet 7's should not be used in patients with type 1 diabetes and for treating diabetic ketoacidosis. Janumap 100 Tablet 7's should not be stopped even if you feel better without consulting your doctor as the sugar levels change. If you stop taking Janumap 100 Tablet 7's abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). Janumap 100 Tablet 7's should not be taken if you have severe kidney or liver disease. Please inform your doctor if you have any heart disease or planning to get pregnant or breastfeed. Prolonged intake of Janumap 100 Tablet 7's may cause acute pancreatitis (swollen pancreas) and critical kidney problem. Increased risk of hypoglycaemia (low blood sugar level) can occur when Janumap 100 Tablet 7's is added to other anti-diabetic agents or insulin therapy. In this case, your doctor may adjust the dose of Janumap 100 Tablet 7's. Severe allergic reactions might occur in some patients taking Janumap 100 Tablet 7's like anaphylaxis, angioedema (swelling under the skin), and exfoliative skin conditions, including Stevens-Johnson syndrome. The safety and efficacy of Janumap 100 Tablet 7's in children under 18 years have not been established, so it should not be given to them. Patients taking digoxin (a heart medicine) with Janumap 100 Tablet 7's should be closely monitored as severe drug interaction has been observed.

Drug-Drug Interactions

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SitagliptinIvacaftor
Severe

Drug-Drug Interactions

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How does the drug interact with Janumap 100 Tablet:
Co-administration of Janumap 100 Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Taking Janumap 100 Tablet with Gatifloxacin is not recommended as it can lead to a possible interaction, However, it can be taken if advised by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not stop using any medications without a doctor's advice.
SitagliptinIvacaftor
Severe
How does the drug interact with Janumap 100 Tablet:
When Janumap 100 Tablet is taken with Ivacaftor, the amount of Janumap 100 Tablet in the blood can go up.

How to manage the interaction:
Taking Janumap 100 Tablet with Ivacaftor together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
SitagliptinTirzepatide
Moderate
How does the drug interact with Janumap 100 Tablet:
As tirzepatide and Janumap 100 Tablet both work through similar pathways in the body, it is possible that using them together may result in an increase in side effects.

How to manage the interaction:
It is essential to inform your doctor about all other medications you are taking, including vitamins and herbal supplements. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Therapeutic Class

ANTIDIABETICS

FAQs

Country of origin

India

Manufacturer/Marketer address

633, Srs Tower, 14/5 Mathura Road, Faridabad - 121003, Haryana
Other Info - JAN0093

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Author Details

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Drug-Diseases Interactions

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SITAGLIPTIN-100MGAcute pancreatitis
Severe
SITAGLIPTIN-100MGChronic kidney disease
Moderate

Drug-Diseases Interactions

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SITAGLIPTIN-100MGAcute pancreatitis
Severe
How does the disease interact with Janumap 100 Tablet:
Pancreatitis: Patients using Janumap 100 Tablet may cause acute pancreatitis. Use cautiously in patients who have a history of pancreatitis or pancreatic disease are at higher risk. Monitor for pancreatitis symptoms and indications. Discontinue therapy if pancreatitis is suspected.

How to manage the interaction:
Janumap 100 Tablet should be used with caution in patients with a history of pancreatitis or pancreatic disease. Patients should be observed for signs and symptoms of pancreatitis during treatment and if pancreatitis is suspected, treatment should be discontinued immediately.
SITAGLIPTIN-100MGChronic kidney disease
Moderate
How does the disease interact with Janumap 100 Tablet:
Renal dysfunction: Assess renal function before initiating Janumap 100 Tablet therapy. Adjust the dose as per moderate to severe renal insufficiency. Otherwise, observed worsening renal function.

How to manage the interaction:
Dose adjustment may be needed in people with moderate to severe renal insufficiency and end stage renal dysfunction.

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