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  1. Home
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  3. Knogle 200 Nasal Spray 60Md 6Ml

Knogle 200 Nasal Spray 60Md 6Ml, Pack of 1 SPRAY
Written By Urvashi Bharti , MBBS
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
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Whats That

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Synonym :

CALCITONIN SALMON

Composition :

CALCITONIN-200IU

Manufacturer/Marketer :

Biodeal Pharmaceuticals Pvt Ltd

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

HYPOCALCEMIC AGENTS

Country of origin

India

Manufacturer/Marketer address

Biodeal Pharmaceuticals Pvt. Ltd. Vill. Saini Majara, Nalagarh Ropar Road,City Nalagarh, Distt.Solan, Himachal Pradesh, 174101.
Other Info - KNO0033

Author Details

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Written By

Urvashi Bharti

MBBS

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:35 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Knogle 200 Nasal Spray 60Md 6Ml contains Calcitonin. It reduces the activity of osteoclasts, which are the cells responsible for bone breakdown. When bone is broken down, the calcium in the bone is released into the bloodstream. As a result, calcitonin's suppression of osteoclasts limits the quantity of calcium released into the blood. Furthermore, it can reduce calcium resorption in the kidneys, resulting in decreased blood calcium levels.

If you have osteoporosis, avoid smoking, or try to quit. Smoking can reduce bone mineral density and increases the risk of fractures.

Knogle 200 Nasal Spray 60Md 6Ml contains Calcitonin, a hormone that regulates the calcium level in the blood. This hormone helps in bone formation and also helps the body to reverse bone loss. Due to this, the number of cells that damages bones becomes comparatively less. Hence, the bone damage is halted. Using Knogle 200 Nasal Spray 60Md 6Ml can increase bone formation by activation of the bone-forming cells.

Persons whose age is more than 45 years have low estrogen levels, females reaching menopause, too much consumption of alcohol, tobacco or caffeine, use of glucocorticoids and lack of calcium and vitamin D in foods are some of the factors that can increase the risk of osteoporosis.

Yes, Knogle 200 Nasal Spray 60Md 6Ml is used together with calcium and vitamin D to treat bone loss in women with postmenopausal osteoporosis who have been postmenopausal for at least five years. Knogle 200 Nasal Spray 60Md 6Ml inhibits the function of osteoclasts (bone breakdown), reducing bone resorption; thus, combining calcium and calcitonin could result in a positive bone balance.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Consuming alcohol while on treatment with Knogle 200 Nasal Spray 60Md 6Ml is not recommended since it may result in unpleasant side effects or make you more susceptible to the effects of alcohol.

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Pregnancy

Caution

Knogle 200 Nasal Spray 60Md 6Ml should be used in pregnancy only when the benefit to the mother outweighs the risk to the foetus. Hence, inform your doctor if you are pregnant or expecting pregnancy.

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Breast Feeding

Caution

Tell your doctor if you are a nursing mother before taking Knogle 200 Nasal Spray 60Md 6Ml; your doctor will decide whether Knogle 200 Nasal Spray 60Md 6Ml can be taken by breastfeeding mothers.

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Driving

Not applicable

Knogle 200 Nasal Spray 60Md 6Ml does not impact your ability to drive or operate machinery.

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Liver

Caution

Inform your doctor before receiving the Knogle 200 Nasal Spray 60Md 6Ml if you have a liver impairment. It should be used with caution in patients with liver conditions as it may alter liver functioning.

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Kidney

Caution

Inform your doctor before receiving the Knogle 200 Nasal Spray 60Md 6Ml if you have kidney impairment. Periodic examinations of urine sediment should be considered as this medicine may cause urine sediment abnormalities.

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Children

Caution

Knogle 200 Nasal Spray 60Md 6Ml is not recommended for children as safety and effectiveness have not been established.

Product Substitutes

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Keep Refrigerated. Do not freeze.Prepaid payment required.

Reference

  1. https://www.drugs.com/cdi/calcitonin-injection.html
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/017808s035lbl.pdf
  3. https://www.hormone.org/your-health-and-hormones/glands-and-hormones-a-to-z/hormones/calcitonin

About Knogle 200 Nasal Spray 60Md 6Ml

Knogle 200 Nasal Spray 60Md 6Ml belongs to groups of medications called hypocalcemic agents, used to treat high blood calcium levels (hypercalcemia) and Postmenopausal Osteoporosis. Besides this, it can also help treat complications of Paget's disease. Hypercalcemia is a condition in which the calcium level in your blood is above normal. Postmenopausal osteoporosis is a medical condition that causes thinning and weakening of the bones during/after a menopausal period. Paget’s disease is a chronic disease of bone that disrupts the replacement of old bone tissue with new bone tissue, resulting in the new bone that is abnormally shaped, weak and brittle.

Knogle 200 Nasal Spray 60Md 6Ml contains Calcitonin. It reduces the activity of osteoclasts, which are the cells responsible for bone breakdown. When bone is broken down, the calcium in the bone is released into the bloodstream. As a result, calcitonin's suppression of osteoclasts limits the quantity of calcium released into the blood. Furthermore, it can reduce calcium resorption in the kidneys, resulting in decreased blood calcium levels.

Knogle 200 Nasal Spray 60Md 6Ml will be administered by a qualified healthcare professional. Kindly do not self-administer. In some cases, Knogle 200 Nasal Spray 60Md 6Ml can cause side effects, including injection site reactions, nausea with or without vomiting and flushing of the face or hands. Most of these side effects of Knogle 200 Nasal Spray 60Md 6Ml do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Before taking the Knogle 200 Nasal Spray 60Md 6Ml, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Knogle 200 Nasal Spray 60Md 6Ml should not be given to children as safety and efficacy have not been established.

Uses of Knogle 200 Nasal Spray 60Md 6Ml

Postmenopausal osteoporosis, Paget’s disease, Hypercalcemia.

Medicinal Benefits Mweb

Medicinal Benefits

Knogle 200 Nasal Spray 60Md 6Ml contains calcitonin, which belongs to groups of medications called hypocalcemic agents and is used to treat high blood calcium levels (hypercalcemia) and Postmenopausal Osteoporosis. On the other hand, it can also help people with Paget's disease of bone. Knogle 200 Nasal Spray 60Md 6Ml reduces the activity of osteoclasts, which are the cells responsible for bone breakdown. When bone is broken down, the calcium in the bone is released into the bloodstream. As a result, calcitonin's suppression of osteoclasts limits the quantity of calcium released into the blood. Furthermore, it can reduce calcium resorption in the kidneys, decreasing blood calcium levels.

Directions for Use

Knogle 200 Nasal Spray 60Md 6Ml will be administrated by a healthcare professional. Do not self-administer.

Side Effects of Knogle 200 Nasal Spray 60Md 6Ml

  • Injection site reactions
  • Nausea with or without vomiting
  • Flushing of the face or hands

Drug Warnings

Before taking the Knogle 200 Nasal Spray 60Md 6Ml, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Knogle 200 Nasal Spray 60Md 6Ml should not be given to children as safety and efficacy have not been established. In rare situations, Knogle 200 Nasal Spray 60Md 6Ml may cause major hypersensitivity reactions in individuals receiving Miacalcin injection, including bronchospasm, inflammation of the tongue or throat and anaphylactic shock. If you encounter any of these symptoms, contact your doctor right once.

Drug-Drug Interactions

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calcitonin (salmon synthetic)Etelcalcetide
Severe

Drug-Drug Interactions

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calcitonin (salmon synthetic)Etelcalcetide
Severe
How does the drug interact with Knogle 200 Nasal Spray 60Md 6Ml:
Etelcalcetide may decrease the calcium levels in the blood. Concomitant use with calcitonin may increase the risk of hypocalcemia, or low blood calcium.

How to manage the interaction:
Although there is an interaction, calcitonin can be taken with etelcalcetide if prescribed by the doctor. Consult the prescriber if you notice symptoms of hypocalcemia like numbness or tingling around your mouth, muscle spasms, or mental changes (irritability, depression, psychosis). Do not discontinue using any medication without contacting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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CALCITONIN-200IUDisorders of mineral metabolism
Moderate
CALCITONIN-200IUDisorders of mineral metabolism
Moderate

Drug-Diseases Interactions

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CALCITONIN-200IUDisorders of mineral metabolism
Moderate
How does the disease interact with Knogle 200 Nasal Spray 60Md 6Ml:
Calcium levels in the serum are reduced . Patients who already have hypocalcemia should use caution when administering calcium to prevent unwanted side effects. It is preferable to address hypocalcemia before beginning medication. A sufficient intake of calcium and vitamin D should be made sure during the course of treatment if calcitonin is used to promote bone mineral density, as in the case of osteoporosis

How to manage the interaction:
Calcitonin may cause hypocalcemic effects. Therefore, it should be administered cautiously to patients with preexisting hypocalcemia, since they may be particularly sensitive to these effects.
CALCITONIN-200IUDisorders of mineral metabolism
Moderate
How does the disease interact with Knogle 200 Nasal Spray 60Md 6Ml:
Prior to beginning medication, hypocalcemia and other abnormalities of mineral metabolism, such as vitamin D deficiency, should be corrected when calcitonin is used to treat osteoporosis. The body must have an adequate quantity of calcium and vitamin D for the necessary increase in bone mineral density to occur. When treating patients with these conditions with calcitonin salmon nasal spray, serum calcium and hypocalcemia symptoms should be kept under close observation. Throughout the course of treatment, it is important to ensure an adequate intake of calcium and vitamin D

How to manage the interaction:
In patients with mineral metabolism disorders, serum calcium and symptoms of hypocalcemia should be monitored during therapy. Appropriate intake of calcium and vitamin D should be ensured throughout the course of treatment.

Drug-Drug Interactions Checker List

  • LITHIUM
  • ETELCALCETIDE
  • FOSCARNET

Habit Forming

No

Special Advise

  • Certain diagnostic tests, like blood tests, measure the calcitonin level in your blood, and bone density scans are used to check bone mineral density (BMD).
  • Clinical monitoring of serum electrolyte concentrations is recommended.

Diet & Lifestyle Advise

  • A person should consume calcium and vitamin D in their diet as it helps make stronger bones and avoid everyday osteoporosis dangers.
  • A post-menopausal woman should limit salt intake as it can pose a high risk of losing more bone minerals than other women of the same age.
  • Do regular exercise like weight-bearing exercises which are important for maintaining bone health.
  • Calcium is important for making bones strong. Vitamin D is equally important, which helps to ensure the absorption and retention of calcium in bones, so take food high in calcium and vitamins.

Knogle 200 Nasal Spray 60Md 6Ml Substitute

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