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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer :

Elben Healthy Care

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

COUGH AND COLD PREPARATIONS

Country of origin

India
Other Info - KOF0070

Author Details

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FAQs

Koffel Syrup contains Chlorpheniramine maleate, Phenylephrine, and Dextromethorphan. Chlorpheniramine works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine is a 'decongestant' that helps in shrinking the blood vessels located in the nasal passage, thereby reducing stuffy nose. Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough.

No, you should not take Koffel Syrup if you need to undergo surgery as it may lead to excessive drowsiness and sleepiness when given along with anaesthesia. Therefore, if you are about to undergo any surgery, please inform your doctor that you are taking Koffel Syrup. Your doctor may advise you to stop taking Koffel Syrup 72 hours before the surgery.

It is not recommended to take Koffel Syrup along with any anti-depressant medication, especially MAO inhibitors (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), as it may lead to unpleasant side-effects or any drug interaction. Also, Koffel Syrup should be taken at least 15 days after your last dose of anti-depressants.

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take Koffel Syrup and skip the missed dose. Do not take extra medicine to make up for the missed dose.

Koffel Syrup should be used with caution and only when prescribed by a doctor in patients with glaucoma, as Koffel Syrup may rarely worsen the symptoms of glaucoma.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Avoid consumption of alcohol with Koffel Syrup as it may increase drowsiness. Please consult a doctor before consuming alcohol with Koffel Syrup.

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Pregnancy

Caution

The safety of Koffel Syrup in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Koffel Syrup is excreted in human milk. Koffel Syrup is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Koffel Syrup may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Koffel Syrup.

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Liver

Caution

Take Koffel Syrup with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Koffel Syrup with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Koffel Syrup is not recommended for children below 4 years of age. However, please consult a doctor before using Koffel Syrup in children.

About Koffel Syrup

Koffel Syrup belongs to a class of medication called 'cough and cold preparations' primarily used to treat dry cough. Coughing (dry or productive) is the body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. There are two types of coughs: dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear your airways. 

Koffel Syrup is a combination of three drugs, namely: Chlorpheniramine maleate (antihistamine), Phenylephrine (decongestant), and Dextromethorphan (cough suppressant). Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough. Collectively, it helps to provide relief from dry cough.

Take Koffel Syrup with or without food as advised by your doctor with the help of a measuring cup. Your doctor will recommend how often you take Koffel Syrup based on your medical condition. Some people may experience dry mouth, throat or nose, drowsiness, blurred vision, constipation, dizziness, restlessness, or excitation. Most of these side effects of Koffel Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please inform your doctor if you are allergic to Koffel Syrup or any other medicines. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Koffel Syrup. Koffel Syrup is not recommended for children below 12 years of age. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Koffel Syrup. Avoid using Koffel Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine, and methylene blue injection in the past 14 days. Drink plenty of fluids while taking Koffel Syrup to loosen mucus.

Uses of Koffel Syrup

Dry Cough

Medicinal Benefits Mweb

Medicinal Benefits

Koffel Syrup contains Chlorpheniramine maleate, Phenylephrine, and Dextromethorphan used to treat dry cough. Chlorpheniramine maleate helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough. Thus, Koffel Syrup helps to relieve overall cough, cold and allergic symptoms.

Directions for Use

Shake the bottle well before use. Check the label for directions and take Koffel Syrup with or without food in doses as prescribed by your doctor with the help of a measuring cup provided with the pack.

Side Effects of Koffel Syrup

  • Dry mouth, throat or nose
  • Drowsiness
  • Dizziness
  • Blurred vision
  • Headache
  • Constipation
  • Restlessness or excitation
  • Loss of appetite

Drug Warnings

Please inform your doctor if you are allergic to Koffel Syrup or any other medicines. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Koffel Syrup. Koffel Syrup is not recommended for children below 4 years of age. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Koffel Syrup. Avoid using Koffel Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. Drink plenty of fluids while taking Koffel Syrup to loosen mucus. If you have glaucoma, urinary problems, enlarged prostate, cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking Koffel Syrup.

Drug-Drug Interactions

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DextromethorphanTranylcypromine
Critical
DextromethorphanSelegiline
Critical

Drug-Drug Interactions

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DextromethorphanTranylcypromine
Critical
How does the drug interact with Koffel Syrup:
Taking Tranylcypromine with Koffel Syrup can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Koffel Syrup with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fit blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
DextromethorphanSelegiline
Critical
How does the drug interact with Koffel Syrup:
Co-administration of Koffel Syrup and Selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Selegiline with Koffel Syrup can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
DextromethorphanProcarbazine
Critical
How does the drug interact with Koffel Syrup:
Co-administration of Koffel Syrup and Procarbazine may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Procarbazine with Koffel Syrup can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
DextromethorphanRasagiline
Critical
How does the drug interact with Koffel Syrup:
Taking Rasagiline with Koffel Syrup can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Koffel Syrup with Rasagiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor. Do not discontinue any medications without consulting a doctor.
DextromethorphanPargyline
Critical
How does the drug interact with Koffel Syrup:
Co-administration of Pargyline and Koffel Syrup can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Koffel Syrup and Pargyline can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanPhenelzine
Critical
How does the drug interact with Koffel Syrup:
Co-administration of Phenelzine and Koffel Syrup can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Phenelzine and Koffel Syrup can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanIsocarboxazid
Critical
How does the drug interact with Koffel Syrup:
Co-administration of Isocarboxazid with Koffel Syrup can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Koffel Syrup and Isocarboxazid can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
PhenylephrineSevoflurane
Critical
How does the drug interact with Koffel Syrup:
Co-administration of Koffel Syrup with Sevoflurane can increase the levels of Koffel Syrup and lead to side effects.

How to manage the interaction:
Taking Koffel Syrup with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
PhenylephrinePropofol
Critical
How does the drug interact with Koffel Syrup:
Taking Koffel Syrup with Propofol may lead to increased levels of Koffel Syrup leading to side effects like high blood pressure.

How to manage the interaction:
Taking Koffel Syrup with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
PhenylephrineSelegiline
Critical
How does the drug interact with Koffel Syrup:
Co-administration of Selegiline with Koffel Syrup together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Koffel Syrup is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • ESCITALOPRAM
  • DESVENLAFAXINE
  • VILAZODONE
  • ACETAMINOPHEN
  • AMOXICILLIN
  • LINEZOLID
  • PHENELZINE
  • SELEGILINE
  • RASAGILINE
  • ISOCARBOXAZID
  • TRANYLCYPROMINE
  • METOPROLOL
  • ATENOLOL
  • CARISOPRODOL
  • CYCLOBENZAPRINE
  • CETIRIZINE

Habit Forming

No

Special Advise

  • Do not use Koffel Syrup only to make a child sleepy. 
  • Contact a doctor if your symptoms do not improve even after 7 days.
  • Contact a doctor immediately if you develop fever, rash or headaches after taking Koffel Syrup. 

Diet & Lifestyle Advise

  • Avoid dairy products such as milk, as it may increase mucus production. Also, avoid processed or refined foods to have relief from cough. 
  • Drink plenty of fluids to avoid dry throat while you have a cough and loosen mucus.
  • Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.

Koffel Syrup Substitute

Substitutes safety advice
  • Decoff-DX Syrup 100 ml

    by Others

    1.19per tablet
  • Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml

    by Others

    0.93per tablet
  • Kolder DMR 100ml Syp

    by Others

    0.85per tablet
  • Kriscoff-DX Sugar Free Syrup 100 ml

    by Others

    0.70per tablet
  • Coughrow-DX Sugar Free Syrup 100 ml

    by Others

    0.70per tablet
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