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  1. Home
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  3. Krabeva 400 mg Injection 16 ml

Krabeva 400 mg Injection 16 ml, Pack of 1 INJECTION
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Know More

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Whats That

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Composition :

BEVACIZUMAB-400MG

Manufacturer/Marketer :

Biocon Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

MONOCLONAL ANTIBODIES

Country of origin

India

Manufacturer/Marketer address

20Th Km, Hosur Road, Electronic City, Bangalore, India - 560 100
Other Info - KRA0034

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:42 AM IST

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FAQs

Krabeva 400 mg Injection works against a protein called vascular endothelial growth factor (VEGF). Inhibition of vascular endothelial growth factor (VEGF) limits the flow of oxygen and nutrients to the tumour cells, causing them to shrink or cease developing. Thereby, Krabeva 400 mg Injection helps treat cancer.

Krabeva 400 mg Injection may reduce the number of red blood cells leading to anaemia. Its symptoms include pale skin, lack of energy, feeling breathless, feeling dizzy and lightheadedness.

Chemotherapy remains necessary. Krabeva 400 mg Injection is given along with chemotherapy for treating cancer.

Krabeva 400 mg Injection may increase the risk of bleeding and problems with wound healing. If you have had major surgery in the past 28days or if the wound hasn't healed, you should not take Krabeva 400 mg Injection. Talk to your doctor for more information.

Cancer can affect anyone, though the risk increases with age. Individual risk is determined by factors such as smoking and drinking habits, lifestyle choices such as what you eat and exercise; a family history of cancer, and factors in your workplace and environment.

Krabeva 400 mg Injection may increase the incidence of hypertension. Therefore, consult your doctor before taking Krabeva 400 mg Injection if you have high blood pressure.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Krabeva 400 mg Injection. It could lead to unpleasant side effects.

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Pregnancy

Unsafe

Krabeva 400 mg Injection should not be used during pregnancy because it causes harm to the fetus. Women of childbearing potential must use an effective contraception method while taking Krabeva 400 mg Injection and at least six months after the last dose. Please consult your doctor about any concerns regarding this.

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Breast Feeding

Unsafe

Avoid breastfeeding during treatment and for 6months after the last dose. This is due to the possibility of the medication being passed on to the infant through breast milk.

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Driving

Caution

Caution should be exercised when driving or operating machinery because in some cases, Krabeva 400 mg Injection may cause sleepiness and fainting.

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Liver

Caution

If you have/had a history of any liver-related diseases, please inform the doctor before taking Krabeva 400 mg Injection. Your doctor will weigh the benefits and potential risks before prescribing Krabeva 400 mg Injection.

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Kidney

Caution

If you have/had a history of any kidney-related diseases, please inform the doctor before taking Krabeva 400 mg Injection. Your doctor will weigh the benefits and potential risks before prescribing Krabeva 400 mg Injection.

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Children

Unsafe

Krabeva 400 mg Injection is not recommended for children below 18years as the safety and effectiveness have not been established.

Product Substitutes

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Keep Refrigerated. Do not freeze.Prepaid payment required.

Reference

  1. https://www.ema.europa.eu/en/documents/product-information/avastin-epar-product-information_en.pdf
  2. https://www.avastin.com/hcp.html
  3. https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/bevacizumab
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/125085s332lbl.pdf
  5. https://www.drugs.com/drug-interactions/bevacizumab.html
  6. https://www.medicines.org.uk/emc/files/pil.3885.pdf

About Krabeva 400 mg Injection

Krabeva 400 mg Injection is a monoclonal antibody used to treat metastatic breast cancer, non-small cell lung cancer, kidney cancer, cervical cancer, epithelial ovarian, fallopian tube, or primary peritoneal cancer, cancer of colon and rectum. Cancer is a condition where cells in a specific part of the body grow and reproduce uncontrollably. Cancer can start in one region of the body and spread to other parts. This is referred to as metastasis.

Krabeva 400 mg Injection contains 'Bevacizumab' that works against vascular endothelial growth factor (VEGF) which is found on the lining of lymph and blood vessels. VEGF causes blood vessels to grow within tumours which provide oxygen and nutrients to the tumour. Inhibition of vascular endothelial growth factor limits the flow of oxygen and nutrients to the tumour, causing it to shrink or cease developing. Thus, it helps treat cancers.

Krabeva 400 mg Injection will be administered by a healthcare professional; do not self-administer. Based on your medical condition, your doctor will decide the dose and duration. In some cases, Krabeva 400 mg Injection may cause loss of appetite, constipation, fever, nosebleeds, change in speech, and taste. The majority of these side effects do not require medical treatment and fade away with time. However, consult your doctor if the side effects persist or worsen

Avoid taking Krabeva 400 mg Injection if you are pregnant. Use effective contraception during the treatment and for 6months after the last dose. Krabeva 400 mg Injection may cause sleepiness and fainting, so avoid driving while on treatment with Krabeva 400 mg Injection. Do not breastfeed during the treatment and for 6months after the last dose of Krabeva 400 mg Injection. Keep your doctor informed about your health condition and all the medicines you take to rule out any side effects.

Uses of Krabeva 400 mg Injection

Metastatic breast cancer, non-small cell lung cancer, kidney cancer, cervical cancer, epithelial ovarian, fallopian tube, or primary peritoneal cancer, cancer of colon and rectum

Medicinal Benefits Mweb

Medicinal Benefits

Krabeva 400 mg Injection contains Bevacizumab, a monoclonal antibody used to treat metastatic breast cancer, non-small cell lung cancer, kidney cancer, cervical cancer, epithelial ovarian, fallopian tube, or primary peritoneal cancer, cancer of colon and rectum. Krabeva 400 mg Injection works against a protein called vascular endothelial growth factor (VEGF). Vascular endothelial growth factor (VEGF) inhibition limits the flow of oxygen and nutrients to the tumour cells, causing them to shrink or cease developing. Thus, it helps treat cancer.

Directions for Use

Krabeva 400 mg Injection will be administered by a healthcare professional; do not self-administer.

Side Effects of Krabeva 400 mg Injection

  • Constipation
  • Loss of appetite
  • Fever
  • Nose bleeds
  • Change in speech
  • Change in taste
  • Voice changes/hoarseness
  • Loss of body weight

Drug Warnings

Krabeva 400 mg Injection should only be taken under medical supervision. While taking Krabeva 400 mg Injection, the doctor will monitor your condition on a regular basis. If you have a history of allergic reactions to Krabeva 400 mg Injection or other medications, inform your doctor before taking it. Avoid taking Krabeva 400 mg Injection if you are pregnant. Use effective contraception during the treatment and for 6months after the last dose. Krabeva 400 mg Injection may cause sleepiness and fainting, so avoid driving while on treatment with Krabeva 400 mg Injection. Inform your doctor if you have/had high blood pressure, heart attack, stroke, bleeding problems, stomach/intestinal bleeding, perforation; if you had surgery in the past 28days/are due to have surgery. Do not breastfeed during the treatment and for 6months after the last dose of Krabeva 400 mg Injection. While taking Krabeva 400 mg Injection, please do not get any immunizations or vaccinations unless your doctor has approved it. Krabeva 400 mg Injection may increase the risk of bleeding, so be cautious and consult your doctor if you notice any bleeding or bruising.

Drug-Drug Interactions

verifiedApollotooltip
BevacizumabClozapine
Severe
BevacizumabThalidomide
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Drug Interactions Checker List

  • SUNITINIB

Habit Forming

No

Special Advise

  • Your doctor may perform routine blood tests to evaluate your liver function, electrolyte levels, and blood cell count.
  • Peripheral blood counts should be closely maintained during the treatment and, if necessary, until recovery.
  • Wear protective clothing, sunglasses, and sunscreen to avoid unnecessary or prolonged exposure to sunlight and UV rays (such as tanning booths). Your skin may become sun-sensitive as a result of Krabeva 400 mg Injection.
  • Peripheral blood counts should be evaluated on a regular basis throughout Krabeva 400 mg Injection treatment and until full recovery is achieved.

Diet & Lifestyle Advise

  • Meditating, reading novels, taking a nice bubble bath, or listening to calming music can all help you relax.
  • Yoga can also aid in the improvement of both physical and mental health.
  • Maintain a healthy weight by engaging in low-strain workouts on a regular basis and consuming nutritious foods.
  • To maintain a healthy weight, eat a portion of nutritious food and exercise on a regular basis.
  • Leafy greens, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs should all be part of your daily diet.
  • Rest well and get a good night's sleep.
  • Avoid smoking and consuming alcoholic beverages.
  • Fast food, fried foods, processed meats, refined carbohydrates, and added sugars should be avoided.

Krabeva 400 mg Injection Substitute

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