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  3. Kryxana 200 mg Tablet 21's

Prescription drug
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sureshvarma D , MPharma

Composition :

RIBOCICLIB-200MG

Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

CHEMOTHERAPY

Country of origin

Switzerland

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - KRY0003

Author Details

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FAQs

Kryxana 200 mg Tablet works by blocking cyclin-dependent kinase 4 and 6 proteins, which are necessary for the growth and division of the cells. Thereby, slows down the growth of cancer cells and delays the progression of cancer.

Kryxana 200 mg Tablet might cause fertility problems and may affect your ability to father a child. Talk to your doctor if you have any concerns regarding this.

Avoid pomegranate/pomegranate juice and grapefruit/grapefruit juice while taking Kryxana 200 mg Tablet as these might increase the amount of Kryxana 200 mg Tablet in blood.

Kryxana 200 mg Tablet may cause a heart problem called QT prolongation, which causes abnormal heartbeat. Inform your doctor if you have/had any heart problems, heart failure, irregular heartbeat, or QT prolongation. Regular monitoring of heart activity before and during treatment with Kryxana 200 mg Tablet is advised.

Do not stop taking Kryxana 200 mg Tablet on your own. You are advised to take Kryxana 200 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Kryxana 200 mg Tablet .

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Avoid alcohol consumption while taking Kryxana 200 mg Tablet as it might cause increased dizziness.

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Pregnancy

Unsafe

Kryxana 200 mg Tablet should not be taken during pregnancy as it might harm the unborn baby. If you are a woman of childbearing potential, use effective contraception while taking Kryxana 200 mg Tablet and for at least 21 days after the last dose.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Kryxana 200 mg Tablet and for at least 21days after the last dose.

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Driving

Unsafe

Kryxana 200 mg Tablet may cause dizziness, tiredness, or spinning sensation. Drive or operate heavy machinery only if you are alert.

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Liver

Caution

Dose adjustment may be necessary. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Kryxana 200 mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established.

About Kryxana 200 mg Tablet

Kryxana 200 mg Tablet belongs to the group of anti-cancer medicines called cyclin-dependent kinase (CDK) inhibitors used to treat a type of breast cancer that is locally advanced or metastatic (has spread to other parts of the body). Breast cancer is a type of cancer that develops in the breast when the breast cells begin to grow abnormally.
 
Kryxana 200 mg Tablet contains ‘Ribociclib’, which works by blocking cyclin-dependent kinase 4 and 6 proteins, which are necessary for the growth and division of the cells. Thereby, slows down the growth of cancer cells and delays the progression of cancer.
 
You are advised to take Kryxana 200 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as diarrhoea, nausea, vomiting, constipation, hair loss, fatigue, dizziness, back pain, and headache. Do not be reluctant to talk with your doctor if you experience any of these side effects persistently.
 
Avoid taking Kryxana 200 mg Tablet if you are pregnant or breastfeeding. Kryxana 200 mg Tablet may cause tiredness and dizziness, so drive only if you are alert. Kryxana 200 mg Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol with Kryxana 200 mg Tablet as it could lead to increased dizziness. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Kryxana 200 mg Tablet

Breast cancer

Medicinal Benefits Mweb

Medicinal Benefits

Kryxana 200 mg Tablet belongs to the group of anti-cancer medicines called cyclin-dependent kinase (CDK) inhibitors used to treat a type of breast cancer that is locally advanced or metastatic (has spread to other parts of the body). Kryxana 200 mg Tablet works by blocking cyclin-dependent kinase 4 and 6 proteins, which are necessary for the growth and division of the cells. Thereby, slows down the growth of cancer cells and delays the progression of cancer.

Directions for Use

Swallow Kryxana 200 mg Tablet as a whole with a glass of water; do not chew or break it.

Side Effects of Kryxana 200 mg Tablet

  • Stomach upset
  • Diarrhoea
  • Nausea
  • Vomiting
  • Tiredness
  • Constipation
  • Hair loss
  • Weakness
  • Dizziness/light-headedness
  • Headache
  • Cough
  • Reduced appetite
  • Painful and frequent urination
  • Fever

Drug Warnings

Do not take Kryxana 200 mg Tablet if you are allergic to any of its components. Talk to your doctor if you have a fever, sore throat, mouth ulcers due to infections, liver problems, heart/heart rhythm disorders, or low levels of electrolytes. Avoid taking Kryxana 200 mg Tablet if you are pregnant or breastfeeding. Kryxana 200 mg Tablet may cause dizziness, so drive only if you are alert. Kryxana 200 mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol with Kryxana 200 mg Tablet as it could lead to increased dizziness. Inform your doctor about your health condition and medications before taking Kryxana 200 mg Tablet to rule out any side effects/interactions.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Kryxana 200 mg Tablet:
When Kryxana 200 mg Tablet is taken with Ranolazine, may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Ranolazine with Rifampicin is not recommended, please consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms such as excessive drowsiness, dizziness, lightheadedness, fainting, confusion, shortness of breath, or heart palpitations. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Kryxana 200 mg Tablet:
Coadministration of Budesonide and Kryxana 200 mg Tablet may increase the absorption of the medication from budesonide into the blood stream.

How to manage the interaction:
Taking Kryxana 200 mg Tablet with Budesonide can cause an interaction, consult a doctor before taking it. Consult a doctor if experience swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. Do not stop using any medications without talking to a doctor.
How does the drug interact with Kryxana 200 mg Tablet:
Combining Infliximab with Kryxana 200 mg Tablet can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Infliximab with Kryxana 200 mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Kryxana 200 mg Tablet:
Taking Lenvatinib and Kryxana 200 mg Tablet together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Lenvatinib and Kryxana 200 mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you experience severe or prolonged diarrhea, vomiting, sudden dizziness, feeling lightheaded or fainting, shortness of breath, or heart palpitations, call your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Kryxana 200 mg Tablet:
Coadministration of baricitinib and Kryxana 200 mg Tablet can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Kryxana 200 mg Tablet if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Kryxana 200 mg Tablet:
Coadministration of Amitriptyline and Kryxana 200 mg Tablet may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amitriptyline with Kryxana 200 mg Tablet may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Kryxana 200 mg Tablet:
Taking Ceritinib with Kryxana 200 mg Tablet may increase the risk of irregular heart rhythm and other side effects.

How to manage the interaction:
Although there is a interaction between Ceritinib and Kryxana 200 mg Tablet, but it can be taken if prescribed by a doctor. If you experience any symptoms like irregular heart rhythm, nausea, vomiting, loss of hunger, mouth sores, abdominal pain, unusual hair loss, weakness, headache, loose stools, or weakness, dizziness, confusion, and shortness of breath, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Kryxana 200 mg Tablet:
Using Kryxana 200 mg Tablet and olaparib can increase the blood levels of olaparib. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.

How to manage the interaction:
Combining Kryxana 200 mg Tablet and olaparib can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Kryxana 200 mg Tablet:
Taking primaquine and Kryxana 200 mg Tablet together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Primaquine and Kryxana 200 mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Kryxana 200 mg Tablet:
When Kryxana 200 mg Tablet is taken with Salmeterol, it can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
There may be a possibility of interaction between Salmeterol and Kryxana 200 mg Tablet, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • PACLITAXEL
  • DOXORUBICIN
  • ZOLPIDEM
  • OXYCODONE
  • SOTALOL

Habit Forming

No

Special Advise

  • To monitor liver functioning, amount of blood cells, and electrolytes, your doctor might advise regular blood tests before and during the treatment with Kryxana 200 mg Tablet .
  • Regular monitoring of heart activity before and during treatment with Kryxana 200 mg Tablet is advised.
  • Kryxana 200 mg Tablet might cause heart rhythm problems, liver problems and neutropenia (low white blood cell count); therefore, regular tests are recommended while taking Kryxana 200 mg Tablet .
  • If you are a woman of childbearing potential, use effective contraception while taking Kryxana 200 mg Tablet and for at least 21 days after the last dose.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

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