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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
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Whats That

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Composition :

LEFLUNOMIDE-10MG

Manufacturer/Marketer :

Renauxe Pharma India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIRHEUMATICS

Country of origin

India

Manufacturer/Marketer address

33/396 C, Mrra- 48A,Mannarakkara Road End Punnurunni East, Vyttila P.O Ernakulam Kl 682019 In
Other Info - LEF0080

Author Details

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FAQs

Lefright-10 Tablet is a disease-modifying antirheumatic drug (DMARD) which stops DNA (genetic material) of the provoked immune system cells required for its survival. Thereby, helps in treating inflammation, redness, and swelling at the damaged site (especially joint).

Lefright-10 Tablet may cause diarrhoea. Drink plenty of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

It might take 4-6 weeks before you notice any benefit. In some cases, it might also take 6 months for you to feel the full effect of Lefright-10 Tablet . Take Lefright-10 Tablet for as long as your doctor has prescribed to treat your condition effectually.

Inform your doctor if you have liver disease, kidney disease, weak immune system and serious infections like pneumonia, or tuberculosis (TB).

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Lefright-10 Tablet . Alcohol intake, along with Lefright-10 Tablet , may cause liver disease.

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Pregnancy

Unsafe

It is not recommended to take Lefright-10 Tablet while you are pregnant. Lefright-10 Tablet may cause serious birth defects.

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Breast Feeding

Unsafe

It is not recommended to take Lefright-10 Tablet while you are breastfeeding. Lefright-10 Tablet passes into breast milk.

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Driving

Caution

Lefright-10 Tablet may cause dizziness and tiredness; do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Please consult your doctor if you have liver impairment before taking Lefright-10 Tablet .

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Kidney

Caution

Please consult your doctor if you have kidney impairment before taking Lefright-10 Tablet .

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Children

Unsafe

Lefright-10 Tablet is not approved for children under the age of 18 years.

About Lefright-10 Tablet

Lefright-10 Tablet belongs to the group of medicines called 'anti-rheumatic agents' used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Psoriatic arthritis is a kind of inflammatory arthritis which occurs in patients with psoriasis (red patches of skin with silvery scales). 

Lefright-10 Tablet contains 'Leflunomide' an isoxazole immunomodulatory agent which works by blocking the formation of genetic material, i.e. DNA required for survival of replicating (dividing) cells of the immune system. As a result, it suppresses the activated immune system to reduce pain, inflammation and swelling. 

Take Lefright-10 Tablet at the same time every day as prescribed by your doctor. In some cases, Lefright-10 Tablet may cause common side-effects such as diarrhoea, nausea, stomach pain, indigestion, rash, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Lefright-10 Tablet if you are pregnant or planning for pregnancy as Lefright-10 Tablet may cause serious congenital disabilities. Lefright-10 Tablet should not be taken by breastfeeding mothers as it passes into breast milk. Lefright-10 Tablet may cause dizziness, so drive with caution. Avoid consuming alcohol along with Lefright-10 Tablet as it could lead to increased dizziness and liver damage. Lefright-10 Tablet may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Uses of Lefright-10 Tablet

Rheumatoid arthritis, Psoriatic arthritis

Medicinal Benefits Mweb

Medicinal Benefits

Lefright-10 Tablet belongs to the group of medicines called anti-rheumatic agents used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Lefright-10 Tablet is a disease-modifying antirheumatic drug (DMARDs) which inhibits an enzyme called dihydroorotate dehydrogenase and has antiproliferative activity (suppresses the cell growth). Thereby, helps in treating inflammation, redness, and swelling.

Directions for Use

Take Lefright-10 Tablet with or without food. Swallow Lefright-10 Tablet as a whole with water; do not crush or chew it.

Side Effects of Lefright-10 Tablet

  • Diarrhoea
  • Nausea
  • Stomach pain
  • Indigestion
  • Rash
  • Hair loss

Drug Warnings

Do not take Lefright-10 Tablet if you are allergic to leflunomide, have severe liverkidney problems, low levels of protein in the blood, immune system problems, bone marrow problems, or serious infections. Lefright-10 Tablet is not recommended to be used in pregnant women, lactating mothers and people below 18 years of age. Talk to your doctor before taking Lefright-10 Tablet if you have/had serious infections like interstitial lung disease (inflammation of lungs), tuberculosis (TB), or pneumonia. Lefright-10 Tablet may cause dizziness, so drive with caution. Lefright-10 Tablet may make you more susceptible to infections; notify the doctor if you develop infections, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Drug-Drug Interactions

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LeflunomideCorticorelin
Severe

Drug-Drug Interactions

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LeflunomideCorticorelin
Severe
How does the drug interact with Lefright-10 Tablet:
Using Lefright-10 Tablet together with Corticorelin may raise the risk of severe infections.

How to manage the interaction:
Taking Lefright-10 Tablet with Corticorelin together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience symptoms like fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, or pain while urinating, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Lefright-10 Tablet:
When Meloxicam and Lefright-10 Tablet are taken together, can increase the risk of liver damage.

How to manage the interaction:
There may be a possibility of interaction between Lefright-10 Tablet and Meloxicam, but it can be taken if prescribed by a doctor. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
How does the drug interact with Lefright-10 Tablet:
Taking Lefright-10 Tablet and lenvatinib can increase the risk of liver problems.

How to manage the interaction:
Taking Lefright-10 Tablet with Lenvatinib together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, feeling cold, joint discomfort, swelling, bruising, skin irritation, itching, not feeling hungry, tiredness, feeling sick, stomach ache, dark urine, liver harm, or bleeding. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Lefright-10 Tablet:
Lefright-10 Tablet can cause liver problems, and combining it with other drugs, such as binimetinib, can raise the risk.

How to manage the interaction:
There may be a possibility of interaction between Lefright-10 Tablet and Caspofungin, but it can be taken if prescribed by a doctor. If you have any of these symptoms, contact your doctor right away. These symptoms include liver problems, fever, rash, itching, loss of appetite, dark urine, stomach pain, unusual bleeding or bruising, feeling tired, and yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
How does the drug interact with Lefright-10 Tablet:
Co-administration of divalproex and Lefright-10 Tablet can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between divalproex and Lefright-10 Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lefright-10 Tablet:
Coadministration of tizanidine and Lefright-10 Tablet can increase the risk of liver problems.

How to manage the interaction:
Taking Tizanidine and Lefright-10 Tablet together can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lefright-10 Tablet:
Enalapril has the potential to cause liver damage; this effect can be increased by the coadministration of medications that affect the liver, such as Lefright-10 Tablet. This effect can be seen even long after discontinuing Lefright-10 Tablet as it stays in your blood longer.

How to manage the interaction:
Although taking Enalapril together with Lefright-10 Tablet may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of liver damage like fever, chills, unusual bleeding, dark-coloured urine, light colour stools, yellowish discolouration of skin and eyes, and abdominal pain. It is advised not to consume alcohol while using these medications as it may increase the damage o the liver. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Lefright-10 Tablet:
The use of Lefright-10 Tablet together with Cabazitaxel may raise the risk of severe infections.

How to manage the interaction:
Taking Cabazitaxel with Lefright-10 Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like infection, sore throat, diarrhea, muscle pain, weight loss, fever, or difficulty breathing, contact your doctor immediately. If you experience any discomfort or burning while urinating, let your doctor know. Do not stop using any medications without talking to your doctor.
How does the drug interact with Lefright-10 Tablet:
Coadministration of Piroxicam and Lefright-10 Tablet can increase the risk of liver damage.

How to manage the interaction:
Although there is a possible interaction between Lefright-10 Tablet and Piroxicam, you can take these medicines together if prescribed by a doctor. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of hunger, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Lefright-10 Tablet:
Combining Imatinib with Lefright-10 Tablet may raise the risk serious infections. Rarely, these medications could potentially harm the liver.

How to manage the interaction:
Co-administration of Lefright-10 Tablet with Imatinib can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms- fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in the coughing fluid, weight loss, red or irritated skin, swelling, body sores, or discomfort or burning when urinating, exhaustion, nausea, vomiting, dark urine, light stools, and/or yellowing of the skin or eyes, unusual bleeding or bruising, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • IBUPROFEN
  • NAPROXEN
  • ACETAMINOPHEN
  • ASPIRIN
  • DULOXETINE
  • PREDNISONE
  • CELECOXIB
  • AZATHIOPRINE
  • MELOXICAM
  • METHOTREXATE
  • ETANERCEPT
  • ADALIMUMAB
  • ABATACEPT
  • INFLIXIMAB
  • HYDROXYCHLOROQUINE

Habit Forming

No

Special Advise

Regular blood tests to monitor your liver function after starting Lefright-10 Tablet , and for every 6-8 weeks are advised.

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

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