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Written By aquibnaseer ,
Reviewed By Sunny S , MBBS

Composition :

CHLOROQUINE-250MG

Manufacturer/Marketer :

Leo Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

Other Info - LEO0021

Author Details

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About Leoquin EC 250 Tablet

Uses of Leoquin EC 250 Tablet

Medicinal Benefits Mweb

Key Benefits

Directions for Use

Side Effects of Leoquin EC 250 Tablet

Drug Warnings

Drug-Drug Interactions

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ChloroquineTelavancin
Critical
ChloroquineAuranofin
Critical

Drug-Drug Interactions

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ChloroquineTelavancin
Critical
How does the drug interact with Leoquin EC 250 Tablet:
Using Leoquin EC 250 Tablet together with telavancin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Telavancin with Leoquin EC 250 Tablet is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquineAuranofin
Critical
How does the drug interact with Leoquin EC 250 Tablet:
Taking Auranofin with Leoquin EC 250 Tablet can increase the risk of blood disorders and other severe side effects

How to manage the interaction:
Taking Auranofin with Leoquin EC 250 Tablet is not recommended, as it may lead to an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Leoquin EC 250 Tablet:
When Pimozide and Leoquin EC 250 Tablet are taken together, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Leoquin EC 250 Tablet with Pimozide is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquineMesoridazine
Critical
How does the drug interact with Leoquin EC 250 Tablet:
Taking Leoquin EC 250 Tablet with Mesoridazine together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Leoquin EC 250 Tablet with Mesoridazine is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Leoquin EC 250 Tablet:
When Thioridazine and Leoquin EC 250 Tablet are taken together, can increase the chance of a serious abnormal heart rhythm

How to manage the interaction:
Taking Leoquin EC 250 Tablet with Thioridazine is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquineAurothioglucose
Critical
How does the drug interact with Leoquin EC 250 Tablet:
Taking Aurothioglucose with Leoquin EC 250 Tablet can cause blood disorders and other severe side effects

How to manage the interaction:
Taking Aurothioglucose with Leoquin EC 250 Tablet is not recommended, as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
ChloroquineAgalsidase beta
Critical
How does the drug interact with Leoquin EC 250 Tablet:
Using Leoquin EC 250 Tablet with Agalsidase beta can reduce the effectiveness of agalsidase beta.

How to manage the interaction:
Taking Agalsidase beta with Leoquin EC 250 Tablet is not recommended, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Leoquin EC 250 Tablet:
When Leoquin EC 250 Tablet is taken with Dronedarone, it may increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Leoquin EC 250 Tablet with Dronedarone is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Leoquin EC 250 Tablet:
Taking Leoquin EC 250 Tablet with Cisapride can increase the risk of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Leoquin EC 250 Tablet with Cisapride is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately.
ChloroquineSaquinavir
Critical
How does the drug interact with Leoquin EC 250 Tablet:
Using saquinavir together with Leoquin EC 250 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Leoquin EC 250 Tablet with Saquinavir is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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CHLOROQUINE-250MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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CHLOROQUINE-250MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking grape fruit products while using Leoquin EC 250 Tablet, can increase the risk of irregular heartbeat, which may result in side effects such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Avoid grape fruit and its products while taking Leoquin EC 250 Tablet.

Drug-Diseases Interactions

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CHLOROQUINE-250MGDisorders of porphyrin and bilirubin metabolism
Severe
CHLOROQUINE-250MGOther cardiac arrhythmias
Moderate

Drug-Diseases Interactions

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CHLOROQUINE-250MGDisorders of porphyrin and bilirubin metabolism
Severe
How does the disease interact with Leoquin EC 250 Tablet:
Porphyria: In porphyria the use of Leoquin EC 250 Tablet may aggravate this condition. Avoid Leoquin EC 250 Tablet use until it is required.

How to manage the interaction:
If the risks aren't expected to outweigh the possible advantages, Leoquin EC 250 Tablet shouldn't be utilized on these patients.
CHLOROQUINE-250MGOther cardiac arrhythmias
Moderate
How does the disease interact with Leoquin EC 250 Tablet:
Arrhythmias:Leoquin EC 250 Tablet has adverse effect like prolongation of QT interval, ventricular arrhythmias and torsades de pointes. Monitor ECG before initiation and during the therapy.

How to manage the interaction:
If you have sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat while taking these medications, whether they are taken together or separately, you should seek immediate assistance from a doctor. A close monitoring of ECG is required.
CHLOROQUINE-250MGEpilepsy
Moderate
How does the disease interact with Leoquin EC 250 Tablet:
Seizures: Leoquin EC 250 Tablet may cause epileptic seizures in susceptible patients. Administer Leoquin EC 250 Tablet in patients with history of epilepsy.

How to manage the interaction:
In those who are vulnerable, Leoquin EC 250 Tablet may result in epileptic fits. Patients who already have epileptic fits or have a low tolerance for seizures may be at greater risk.
CHLOROQUINE-250MGOther diseases of blood and blood-forming organs
Moderate
How does the disease interact with Leoquin EC 250 Tablet:
Bone marrow suppression: With the use of Leoquin EC 250 Tablet adverse effects such as neutropenia, agranulocytosis, aplastic anemia, and thrombocytopenia. In patients with preexisting bone marrow suppression use cautiously and monitor for complete blood count. Discontinue the Leoquin EC 250 Tablet if any serious blood disorder is suspected.

How to manage the interaction:
It is important to inform your doctor if you have prior conditions like bone marrow suppression, a complete blood picture is advised to be taken if you are on a long term therapy with Leoquin EC 250 Tablet. If you suspect any blood disorders, please inform it to your doctor immediately.
CHLOROQUINE-250MGOther hearing loss
Moderate
How does the disease interact with Leoquin EC 250 Tablet:
Ototoxicity: Rarely, Leoquin EC 250 Tablet was been associated with ototoxicity.The use of Leoquin EC 250 Tablet has been associated rarely with ototoxicity. With long-term, high-dose Leoquin EC 250 Tablet therapy which is irreversible nerve-type deafness may occur. In some patients with preexisting auditory damage, tinnitus, decrease in hearing may occur. Use with caution and discontinue therapy if new auditory defects occur or if hearing loss becomes worse.

How to manage the interaction:
If you any existing hearing damage, do not forget to inform it your doctor, so that a close monitoring can be done during the treatment with Leoquin EC 250 Tablet.
CHLOROQUINE-250MGPsoriasis
Moderate
How does the disease interact with Leoquin EC 250 Tablet:
In psoriasis patients, the Leoquin EC 250 Tablet use may exacerbate severe attack of psoriasis. Do not use Leoquin EC 250 Tablet unless the potential benefits vs risks outweighs.

How to manage the interaction:
It is important to tell your doctor if you have any existing skin conditions like psoriasis. Your doctor may prescribe the medication, if the benefits are more than the risks.
CHLOROQUINE-250MGMyasthenia gravis and other myoneural disorders
Moderate
How does the disease interact with Leoquin EC 250 Tablet:
myasthenia gravis Use of Leoquin EC 250 Tablet may exacerbate new onset of symptoms in patients with previously diagnosed myasthenia gravis. Use cautiously.

How to manage the interaction:
If you are suffering from myasthenia gravis, do not forget to tell it to your doctor. If you are taking Leoquin EC 250 Tablet and experiencing symptoms like muscle weakness or weakness of the arms and legs, drooping of upper eyelid, difficulty speaking, difficulty swallowing, double vision, tiredness, or shortness of breath please inform your doctor.

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