Lesom Capsule belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD). Gastroesophageal reflux disease occurs when stomach acid frequently flows back into the food pipe (oesophagus); this causes acidity, pain and heartburn. Symptoms include heartburn, sour or bitter taste in the mouth and difficulty swallowing.

Lesom Capsule contains Esomeprazole and Levosulpiride. Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Lesom Capsule helps in preventing acid reflux, thereby providing relief from acidity and heartburn.

You are advised to take Lesom Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, abdominal pain, constipation, diarrhoea, flatulence, nausea and vomiting. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Inform your doctor before taking Lesom Capsule if you have a history of gastrointestinal bleeding or intestinal obstruction. On long-term treatment, Lesom Capsule may increase the risk of bone fractures. Consult your doctor if you are pregnant or breastfeeding. Lesom Capsule may cause drowsiness and dizziness, so drive only if you are alert. Lesom Capsule should not be given to children as safety has not been established. Avoid consuming alcohol along with Lesom Capsule as it could lead to increased drowsiness and can elevate the production of stomach acid.

Lesom Capsule belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD). Lesom Capsule is a combination of two drugs, namely: Esomeprazole (proton pump inhibitor) and Levosulpiride (prokinetic agent). Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Lesom Capsule helps in preventing acid reflux, thereby providing relief from acidity and heartburn.

Do not take Lesom Capsule if you are allergic to any of its contents, if you are taking nelfinavir (anti-HIV), if you have a gastrointestinal haemorrhage, mechanical obstruction or perforation, epilepsy, mania, porphyria, or cardiac impairment. Inform your doctor before taking Lesom Capsule if you have severe liver or kidney problems; if you are due to have Chromogranin A test; if you experience unexplained weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black stools. On long-term treatment, Lesom Capsule may increase the risk of bone fractures. Do not take Lesom Capsule if you are pregnant or breastfeeding. Lesom Capsule may cause dizziness and drowsiness, so drive only if you are alert. Lesom Capsule should not be given to children as safety has not been established. Avoid consuming alcohol along with Lesom Capsule as it could lead to increased drowsiness and can elevate the production of stomach acid. 

• Lesom Capsule may cause changes in blood tests for checking liver functioning. Inform the person doing the tests that you are taking Lesom Capsule .
• Inform your doctor before taking Lesom Capsule if you are due to have Chromogranin A test.