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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

LETROZOLE-5MG

Manufacturer/Marketer :

Octob Lifesciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

CHEMOTHERAPY

Country of origin

India
Other Info - LET0136

Author Details

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FAQs

Letrosar-5 Talet works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme Letrosar-5 Talet prevents the growth of cancer cells. Thereby, Letrosar-5 Talet helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

Letrosar-5 Talet causes dizziness and drowsiness. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.

High blood pressure could be a side-effect of Letrosar-5 Talet. Regularly monitor blood pressure levels while taking Letrosar-5 Talet. Consult your doctor if you regularly notice high blood pressure levels.

Do not stop taking Letrosar-5 Talet on your own. You are advised to take Letrosar-5 Talet for as long as your doctor has prescribed it for you depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Letrosar-5 Talet.

Letrosar-5 Talet may cause osteoporosis (bone thinning) due to the reduction of estrogen in the body. Regular bone density tests may help you monitor osteoporosis. Contact your doctor if you observe any sign of tendon pain or swelling while taking Letrosar-5 Talet.

Letrosar-5 Talet may cause weight gain due to an increase in appetite. Eat a healthy diet and exercise regularly to maintain proper weight.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Letrosar-5 Talet to avoid unpleasant side effects. Alcohol intake, along with Letrosar-5 Talet, may cause increased drowsiness.

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Pregnancy

Unsafe

Letrosar-5 Talet is pregnancy category D medicine so, should not be taken during pregnancy.

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Breast Feeding

Unsafe

Letrosar-5 Talet should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby.

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Driving

Caution

Letrosar-5 Talet may cause dizziness and drowsiness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Safe if prescribed

It is safe to take Letrosar-5 Talet if prescribed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Safe if prescribed

It is safe to take Letrosar-5 Talet if prescribed. Please consult your doctor if you have kidney impairment or any concerns regarding this. No dosage adjustment is required for kidney patients with creatinine clearance greater than 10 mL/min.

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Children

Unsafe

Letrosar-5 Talet should not be used by children, as the efficacy and safety have not been established.

About Letrosar-5 Talet

Letrosar-5 Talet belongs to the group of anti-cancer medicines called aromatase inhibitors used to treat breast cancer in women who have gone through menopause (cessation of menses periods). Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen.
 
Letrosar-5 Talet contains 'Letrozole' that works by blocking the aromatase enzyme, which is involved in the production of the estrogen hormone. The cancer cells require estrogen for their growth. Hence, by blocking the aromatase enzyme, Letrosar-5 Talet prevents the growth of cancer cells. Thereby Letrosar-5 Talet helps in preventing or stopping the growth of spreading the tumours (cancer cells) to other body parts.

You are advised to take Letrosar-5 Talet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, Letrosar-5 Talet may cause certain common side-effects such as hypercholesterolemia (increased cholesterol levels), tiredness, weakness, increased sweating, feeling unwell, pain in joints, and hot flushes (feeling of warmth). Do not be reluctant to talk with your doctor if you experience any of these side-effects persistently.
 
Avoid taking Letrosar-5 Talet if you are pregnant or breastfeeding. Letrosar-5 Talet may cause drowsiness and dizziness, so drive only if you are alert. Letrosar-5 Talet should not be given to children as safety has not been established. Avoid consuming alcohol along with Letrosar-5 Talet as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications to rule out any side-effects.

Uses of Letrosar-5 Talet

Breast cancer

Medicinal Benefits Mweb

Medicinal Benefits

Letrosar-5 Talet belongs to the group of anti-cancer medicines called aromatase inhibitors. Letrosar-5 Talet is used to treat breast cancer in women who have gone through menopause (cessation of periods). Letrosar-5 Talet works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme Letrosar-5 Talet prevents the growth of cancer cells. Thereby, Letrosar-5 Talet helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

Directions for Use

Take Letrosar-5 Talet with or without food. Swallow Letrosar-5 Talet as a whole with a glass of water; do not chew or break it. Take Letrosar-5 Talet at the same time every day.

Side Effects of Letrosar-5 Talet

  • Hypercholesterolemia (increased cholesterol levels)
  • Tiredness
  • Weakness
  • Increased sweating
  • Feeling unwell
  • Pain in joints
  • Hot flushes (feeling of warmth)

Drug Warnings

Do not take Letrosar-5 Talet if you are allergic to any of its contents, if you have not yet gone through menopause (still get your periods). Talk to your doctor before taking Letrosar-5 Talet if you have osteoporosis (thinning of bones), bone fractures, severe liver or kidney disease. Letrosar-5 Talet may cause inflammation in tendons or tendon injury; contact your doctor if you observe any sign of tendon pain or swelling while taking Letrosar-5 Talet. Avoid taking Letrosar-5 Talet if you are pregnant or breastfeeding. Letrosar-5 Talet may cause drowsiness and dizziness, so drive only if you are alert. Letrosar-5 Talet should not be given to children as safety has not been established. Avoid consuming alcohol along with Letrosar-5 Talet as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications before taking Letrosar-5 Talet to rule out any side-effects. 

Drug-Drug Interactions

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LetrozoleDiethylstilbestrol
Severe

Drug-Drug Interactions

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How does the drug interact with Letrosar-5 Talet:
Co-administration of Desogestrel together with Letrosar-5 Talet may decrease the effects of Letrosar-5 Talet.

How to manage the interaction:
Although taking Letrosar-5 Talet and Desogestrel together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any medications.
LetrozoleDiethylstilbestrol
Severe
How does the drug interact with Letrosar-5 Talet:
Co-administration of Letrosar-5 Talet may have an effect when used with Diethylstilbestrol, making it less effective in treating your disease.

How to manage the interaction:
Although taking Letrosar-5 Talet and diethylstilbestrol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Letrosar-5 Talet:
Letrosar-5 Talet may have a negative effect when used with Estradiol, making it less effective in treating your disease.

How to manage the interaction:
Although taking Letrosar-5 Talet and estradiol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
LetrozoleConjugated Estrogens
Severe
How does the drug interact with Letrosar-5 Talet:
Coadministration of Conjugated estrogens with Letrosar-5 Talet may reduce the effect of Letrosar-5 Talet.

How to manage the interaction:
Although taking Conjugated estrogen and Letrosar-5 Talet together can result in an interaction, it can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Letrosar-5 Talet:
Coadministration of thalidomide and Letrosar-5 Talet may increase the risk of blood clots.

How to manage the interaction:
Although taking Letrosar-5 Talet and thalidomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, consult a doctor. Do not discontinue any medications without a doctor's advice.
LetrozoleEstrone
Severe
How does the drug interact with Letrosar-5 Talet:
When taken together Letrosar-5 Talet's function could be blocked by estrone, which would reduce its ability to effectively treat your illness.

How to manage the interaction:
Although taking Letrosar-5 Talet and estrone together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Letrosar-5 Talet:
When taken together ethinyl estradiol may interfere with Letrosar-5 Talet's activity and make it less effective in treating the condition.

How to manage the interaction:
Although taking Letrosar-5 Talet and ethinylestradiol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Letrosar-5 Talet:
when taken together Letrosar-5 Talet's function could be blocked by estramustine, which would reduce its ability to effectively treat your illness.

How to manage the interaction:
Although taking Letrosar-5 Talet and estramustine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Letrosar-5 Talet:
Co-administration of Letrosar-5 Talet and Citalopram may raise the risk of a serious irregular heartbeat.

How to manage the interaction:
Although taking Letrosar-5 Talet and Citalopram together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, rapid heartbeat, you should consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CITALOPRAM
  • ESCITALOPRAM
  • TAMOXIFEN

Habit Forming

No

Special Advise

  • Your doctor may advise you to regularly measure bone density before, during and after the treatment as Letrosar-5 Talet may cause bone thinning due to reduction of estrogens in the body.
  • Letrosar-5 Talet should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Letrosar-5 Talet.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Letrosar-5 Talet Substitute

Always consult your doctor before taking any new medications and supplements

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