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  3. Levo-Anawin 0.5% Injection 20 ml

Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

LEVOBUPIVACAINE-5MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

LOCAL ANESTHETICS

Country of origin

India

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - LEV0938

FAQs

Levo-Anawin 0.5% Injection temporarily blocks the pain signals from the nerves of the painful area to the brain, causing numbness at the affected site and relieving pain.

Levo-Anawin 0.5% Injection may affect your blood pressure. It is advised to inform your doctor before using Levo-Anawin 0.5% Injection if you have high blood pressure during pregnancy or low blood pressure.

In addition to Levo-Anawin 0.5% Injection, your doctor may prescribe certain other medications to help with pain management. This may help you get quick results and make you less prone to the side effects of other pain-relieving medicines.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid alcohol consumption as it may cause increased drowsiness.

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Pregnancy

Caution

Levo-Anawin 0.5% Injection may be unsafe to use during pregnancy as it may show harmful effects on the foetus. Please consult your doctor before receiving Levo-Anawin 0.5% Injection if you are pregnant or planning to conceive.

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Breast Feeding

Safe if prescribed

Levo-Anawin 0.5% Injection passes into breastmilk. Hence, if you are breastfeeding, inform your doctor before receiving Levo-Anawin 0.5% Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Not applicable

Levo-Anawin 0.5% Injection will be administered before surgical procedures.

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Liver

Caution

Patients with hepatic disease should use Amide local anaesthetics, like levobupivacaine, with caution, as the liver metabolizes these drugs. Individuals who suffer from severe liver disease are more susceptible to toxic plasma concentrations due to their impaired ability to metabolize local anaesthetics safely.

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Kidney

Consult your doctor

Limited information is available on the use of Levo-Anawin 0.5% Injection in patients with kidney problems. Hence, If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Levo-Anawin 0.5% Injection.

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Children

Consult your doctor

Levo-Anawin 0.5% Injection is recommended for infiltration analgesia (ilioinguinal/iliohypogastric blocks) in children older than six months. Consult your doctor for more information.

About Levo-Anawin 0.5% Injection

Levo-Anawin 0.5% Injection is a local anaesthetic medicine used to reduce pain and discomfort during medical procedures. It produces local numbness and relieves pain. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. The tolerance level of pain might vary from person to person.

Levo-Anawin 0.5% Injection contains Levobupivacaine as an active ingredient, which belongs to the group of medicines called 'amide-type anaesthetics'. It works by acting on the nervous system and nerves to block the transmission of pain signals in the pain area, which results in the loss of pain.

Levo-Anawin 0.5% Injection may cause certain side effects such as weakness, tingling, restlessness, drowsiness, headache, blurred vision, difficulty speaking, irregular heartbeat, chills or shivering, back pain, nausea and vomiting. These side effects may not be similar to everyone and vary individually. If any of these side effects bother you, inform your doctor. Levo-Anawin 0.5% Injection will be administered by the doctor or the nurse before the surgery.

Inform your doctor if you have liver, kidney or heart diseases, high or low blood pressure, excess fat in the body and breathing problems before administering Levo-Anawin 0.5% Injection. This medicine is contraindicated in patients with severe hypotension, cardiogenic or hypovolaemic shock, the paracervical block in obstetrics and intravenous regional anaesthesia. Levo-Anawin 0.5% Injection is recommended for infiltration analgesia (ilioinguinal/iliohypogastric blocks) in children older than six months.

Uses of Levo-Anawin 0.5% Injection

Surgical Anaesthesia, Pain Management

Medicinal Benefits Mweb

Medicinal Benefits

Levo-Anawin 0.5% Injection contains Levobupivacaine, used to relieve pain and discomfort during labour, surgery, dental treatment and other medical procedures. It works by blocking the transmission of pain signals in the pain area by acting on the nervous system and nerves. This blockage causes the loss of pain sensation helps in numbing the localized area, and provides relief from pain. Levo-Anawin 0.5% Injection is injected as an epidural injection at the spinal cord during labour and Caesarean section to prevent labour pain.

Directions for Use

Levo-Anawin 0.5% Injection will be administered by a healthcare professional; do not self-administer.

Side Effects of Levo-Anawin 0.5% Injection

  • Weakness
  • Restlessness
  • Drowsiness
  • Headache
  • Blurred vision
  • Irregular heartbeat
  • Hypotension
  • Chills
  • Back pain
  • Nausea
  • Vomiting 
  • Difficulty speaking

Drug Warnings

Inform your doctor if you have liver, kidney or heart diseases, high or low blood pressure, excess fat in the body and breathing problems before starting Levo-Anawin 0.5% Injection. This medicine is contraindicated in patients with severe hypotension, such as cardiogenic or hypovolemic shock, for use in the paracervical block in obstetrics and for intravenous regional anaesthesia. Levo-Anawin 0.5% Injection is not recommended for children 12 years of age. Let your doctor know about your complete medical and medication history, including prescription and non-prescription medications, vitamins and herbal supplements, before starting Levo-Anawin 0.5% Injection. Levo-Anawin 0.5% Injection released into breast milk during breastfeeding. Please inform your doctor if you are pregnant, planning to conceive or a breastfeeding mother. Avoid alcohol to prevent the worsening of side effects further.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Levo-Anawin 0.5% Injection 20 ml:
Taking Phenobarbital with Levo-Anawin 0.5% Injection 20 ml can increase the risk of methemoglobinemia (a condition in which the iron in the hemoglobin molecule is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although there is a possible interaction between Levo-Anawin 0.5% Injection 20 ml and Phenobarbital, you can take these medicines together if prescribed by a doctor. Seek immediate medical attention if they develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without talking to a doctor.
How does the drug interact with Levo-Anawin 0.5% Injection 20 ml:
Coadministration of Levo-Anawin 0.5% Injection 20 ml and glyceryl trinitrate can increase the risk of developing methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Levo-Anawin 0.5% Injection 20 ml and glyceryl trinitrate together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as grey discolouration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Levo-Anawin 0.5% Injection 20 ml:
Levo-Anawin 0.5% Injection 20 ml has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with hydroxycarbamide, which may lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficit may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking hydroxycarbamide and Levo-Anawin 0.5% Injection 20 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Levo-Anawin 0.5% Injection 20 ml:
Taking phenazopyridine with Levo-Anawin 0.5% Injection 20 ml can increase the risk of methemoglobinemia(a blood disorder in which too little oxygen is delivered to the cells).

How to manage the interaction:
Although there is a drug interaction between phenazopyridine and Levo-Anawin 0.5% Injection 20 ml but can be taken together if advised by a doctor. If experience nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, fast breathing, fast heartbeat, anxiety and confusion contact doctor immediately. Do not discontinue medications without consulting a doctor.
How does the drug interact with Levo-Anawin 0.5% Injection 20 ml:
Taking Chloroquine with Levo-Anawin 0.5% Injection 20 ml can increase the risk of methemoglobinemia( blood disorder that affects how red blood cells deliver oxygen throughout your body).

How to manage the interaction:
Co-administration of Levo-Anawin 0.5% Injection 20 ml with Chloroquine can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Levo-Anawin 0.5% Injection 20 ml:
Combining Nitrofurantoin with Levo-Anawin 0.5% Injection 20 ml can increase the risk of methemoglobinemia (a condition in which the iron in the hemoglobin molecule (the red blood pigment) is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
There may be a possibility of interaction between Nitrofurantoin and Levo-Anawin 0.5% Injection 20 ml, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include a condition called methemoglobinemia, problems with your heart or lungs, your skin turning gray, feeling sick to your stomach, having a headache, feeling dizzy or lightheaded, being very tired, having trouble breathing, breathing quickly or not deeply enough, a fast heartbeat, feeling your heart pounding, feeling anxious or confused. Do not stop using any medications without a doctor's advice.
How does the drug interact with Levo-Anawin 0.5% Injection 20 ml:
Co-administration of Cyclophosphamide with Levo-Anawin 0.5% Injection 20 ml can increase the risk of methemoglobinemia (low level of oxygen in the blood).

How to manage the interaction:
Co-administration of Levo-Anawin 0.5% Injection 20 ml with Cyclophosphamide can possibly result in an interaction, but it can be taken if a doctor has advised it. Keep a close eye on any signs or symptoms of Methemoglobinemia. If you notice any of these symptoms like gray skin, feeling sick, headaches, dizziness, tiredness, or trouble breathing, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
LevobupivacaineNitroprusside
Severe
How does the drug interact with Levo-Anawin 0.5% Injection 20 ml:
Co-administration of Levo-Anawin 0.5% Injection 20 ml and Nitroprusside can rarely cause methemoglobinemia(a condition that can reduce oxygen-carrying capacity of the blood).

How to manage the interaction:
Co-administration of Levo-Anawin 0.5% Injection 20 ml and Nitroprusside can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like grey discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Levo-Anawin 0.5% Injection 20 ml:
Taking isosorbide dinitrate with Levo-Anawin 0.5% Injection 20 ml may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking isosorbide dinitrate and Levo-Anawin 0.5% Injection 20 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
How does the drug interact with Levo-Anawin 0.5% Injection 20 ml:
C0administration of bupivacaine with Levo-Anawin 0.5% Injection 20 ml can have additive toxic effects, so using them together increases the risk of serious side effects like methemoglobinemia (a condition that can deprive tissues and organs of oxygen), reactions in the central nervous system (e.g-convulsions, unconsciousness, coma, respiratory arrest), and cardiovascular disorders (e.g- low blood pressure, heart block, irregular heart rhythm).

How to manage the interaction:
There may be a possibility of interaction between Bupivacaine and Levo-Anawin 0.5% Injection 20 ml, but it can be taken if prescribed by a doctor. However, if you experience pale, grey, or blue-coloured skin, headache, rapid heart rate, shortness of breath, lightheadedness, or fatigue, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • LIDOCAINE
  • PHENYLEPHRINE
  • VASOPRESSIN
  • AMIODARONE

Habit Forming

No

Special Advise

  • Monitor your blood pressure regularly since Levo-Anawin 0.5% Injection may affect your blood pressure.
  • Careful monitoring of respiratory functions is needed while on treatment with Levo-Anawin 0.5% Injection.

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle exercises like 20-30 minutes of walking or swimming would be helpful.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, and apply a cold or hot compress on the painful areas for 15-20 minutes regularly.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

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