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  3. Lopimune Tablet 60's

Written By Veda Maddala , M Pharmacy
Reviewed By Hari Kumar , MBBS
48 Hrs returnable
Know More
COD available

Online payment accepted

Lopimune Tablet 60's, Pack of 1
Lopimune Tablet 60's, Pack of 1
Lopimune Tablet 60's, Pack of 1
Lopimune Tablet 60's, Pack of 1
Lopimune Tablet 60's, Pack of 1
Lopimune Tablet 60's, Pack of 1
rxMedicinePrescription drug

Whats That

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Composition :

LOPINAVIR-200MG + RITONAVIR-50MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

Therapeutic Class

ANTIRETROVIRAL AGENTS

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - LOP0014

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Hari Kumar

Reviewed By

Hari Kumar

MBBS

Last Updated

Aug 20, 2024 | 1:08 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Lopimune Tablet contains Lopinavir and Ritonavir. Lopinavir works by inhibiting the working of a protease enzyme that is essential for the reproduction of the HIV virus. Thereby, it prevents the production of the new virus. Ritonavir slows the breakdown of Lopinavir by the liver and increases the levels of Lopinavir in blood and makes it effective against the virus. Together, they help to control HIV infection.

Lopimune Tablet should be used with caution in diabetic patients as it may increase blood sugar levels. However, if you experience increased thirst or urination, weight loss or fruity breath smell while taking Lopimune Tablet , please consult a doctor immediately as these might be signs of high blood sugar levels.

Lopimune Tablet may cause bone problems such as osteonecrosis (death of bone tissue due to loss of blood supply to the bone) especially in HIV patients taking combination antiretroviral therapy. However, if you experience joint pains, stiffness (especially of shoulder, knee or hip) or difficulty in movement, please consult a doctor immediately.

HIV infection may still be transmitted to other persons while using Lopimune Tablet . Lopimune Tablet reduces the risk of transmission but still, HIV infection is contagious. Therefore, discuss with a doctor regarding precautions to be taken to avoid transmission of HIV while taking Lopimune Tablet .

Lopimune Tablet is not recommended for patients with severe liver problems including chronic hepatitis B or C infection as it may increase the risk of severe liver side effects. Therefore, inform your doctor if you have a history of any liver problems before taking Lopimune Tablet .

Lopimune Tablet does not cure HIV infection. Lopimune Tablet reduces the amount of HIV virus in the body and improves the functioning of the immune system.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid alcohol consumption with Lopimune Tablet as it may increase the risk of liver damage.

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Pregnancy

Caution

Lopimune Tablet is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Breastfeeding mothers are not recommended to take Lopimune Tablet unless advised by a doctor. Therefore, please consult a doctor if you are breastfeeding.

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Driving

Caution

Lopimune Tablet may cause dizziness in some people. Therefore, avoid driving or operating heavy machinery if you feel dizzy after taking Lopimune Tablet .

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Liver

Caution

Take Lopimune Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Lopimune Tablet if you have severe liver problems.

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Kidney

Caution

Take Lopimune Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Lopimune Tablet is not recommended for children below 2 years of age as the safety and effectiveness were not established.

Product Substitutes

Reference

  1. https://www.medicines.org.uk/emc/files/pil.10452.pdf
  2. https://www.drugs.com/mtm/lopinavir-and-ritonavir.html#interactions

About Lopimune Tablet

Lopimune Tablet belongs to a class of drugs called antiretrovirals used in the treatment of HIV infection. Lopimune Tablet helps in decreasing the chance of developing AIDS (acquired immunodeficiency syndrome). Lopimune Tablet may be used in combination with other antiviral drugs. HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses.

Lopimune Tablet is a combination of two antiretroviral drugs, namely: Lopinavir and Ritonavir. Lopinavir works by inhibiting the working of a protease enzyme that is essential for the reproduction of HIV. Thereby, it prevents the production of the new virus. Ritonavir slows the breakdown of Lopinavir by the liver and increases the levels of Lopinavir in the blood and making it effective against the virus. Together, they help to control HIV infection.

Take Lopimune Tablet as prescribed by your doctor. You are advised to take Lopimune Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience nausea, vomiting, diarrhea, upper respiratory tract infection, indigestion, decreased appetite, headache, or dizziness. Most of these side effects of Lopimune Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Lopimune Tablet or any other medicines, please tell your doctor. Lopimune Tablet is not recommended for children below 2 years of age as the safety and effectiveness were not established. If you are pregnant, planning for pregnancy, or breastfeeding, please consult a doctor before taking Lopimune Tablet . You are recommended to avoid the consumption of alcohol with Lopimune Tablet as it may increase the risk of liver damage. Drive only if you are alert as Lopimune Tablet may cause dizziness.

Uses of Lopimune Tablet

HIV infection

Medicinal Benefits Mweb

Medicinal Benefits

Lopimune Tablet contains Lopinavir and Ritonavir used in the treatment of HIV infection. Lopimune Tablet may be used in combination with other antiviral drugs. Lopinavir inhibits the working of the protease enzyme that is essential for the reproduction of HIV. Thereby, it prevents the production of the new virus. Ritonavir slows the breakdown of Lopinavir by the liver and increases the levels of Lopinavir in the blood and making it effective against the virus. Together, they help to control HIV infection by slowing the spread of infection in the body. Taking Lopimune Tablet along with practicing safe sex and lifestyle changes may reduce the risk of getting or transmitting HIV to others.

Directions for Use

Take Lopimune Tablet with or without food as prescribed by your doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Side Effects of Lopimune Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Upper respiratory tract infection
  • Indigestion
  • Decreased appetite
  • Headache
  • Dizziness

Drug Warnings

If you are allergic to Lopimune Tablet or any other medicines, please tell your doctor. Lopimune Tablet is not recommended for children below 2 years of age as the safety and effectiveness were not established. If you are pregnant or planning for pregnancy, please consult a doctor before taking Lopimune Tablet . HIV-infected women are recommended to avoid breastfeeding as the baby may be infected through breast milk. Please consult a doctor if you are breastfeeding before taking Lopimune Tablet . You are recommended to avoid consumption of alcohol with Lopimune Tablet as it may increase the risk of liver damage. Drive only if you are alert as Lopimune Tablet may cause dizziness. You are advised to take proper precautions if you are infected with HIV infection to prevent the spread of infection to others through sexual contact or body fluids. If you experience stomach pain, difficulty in breathing, vomiting, nausea and severe weakness in the muscles of arms and legs, please consult a doctor immediately as these might be symptoms of increased lactic acid levels.

Drug-Drug Interactions

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RitonavirFlecainide
Critical
RitonavirSimvastatin
Critical

Drug-Drug Interactions

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RitonavirFlecainide
Critical
How does the drug interact with Lopimune Tablet:
Coadministration of Flecainide with Lopimune Tablet can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Flecainide with Lopimune Tablet is generally avoided, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms like chest tightness, dizziness, shortness of breath, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RitonavirSimvastatin
Critical
How does the drug interact with Lopimune Tablet:
Taking Lopimune Tablet and Simvastatin may increase the risk of side effects.

How to manage the interaction:
Taking Simvastatin with Lopimune Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, tiredness, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, contact a doctor. Do not discontinue any medications without consulting a doctor.
RitonavirPhenobarbital
Critical
How does the drug interact with Lopimune Tablet:
Taking Phenobarbital with Lopimune Tablet may significantly reduce the blood levels of Lopimune Tablet.

How to manage the interaction:
Taking Phenobarbital with Lopimune Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. If you notice any unusual symptoms consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
RitonavirRanolazine
Critical
How does the drug interact with Lopimune Tablet:
Taking Lopimune Tablet and Ranolazine may significantly increase the blood levels and effects of Ranolazine.

How to manage the interaction:
Co-administration of Ranolazine with Lopimune Tablet can possibly result in an interaction, but it can be taken if a doctor has advised it. In case you experience any symptoms like feeling lightheaded, fainting, or rapid heartbeats, consult a doctor. Do not stop using any medications without a doctor's advice.
RitonavirTolvaptan
Critical
How does the drug interact with Lopimune Tablet:
Taking Lopimune Tablet and Tolvaptan may significantly increase the blood levels of tolvaptan.

How to manage the interaction:
Taking Tolvaptan with Lopimune Tablet is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, fits, contact a doctor. Do not discontinue any medications without consulting a doctor.
RitonavirSildenafil
Critical
How does the drug interact with Lopimune Tablet:
Coadministration of Lopimune Tablet and Sildenafil may significantly increase the blood levels of sildenafil.

How to manage the interaction:
Taking Sildenafil with Lopimune Tablet together is generally avoided as it can possibly result in an interaction, it can be taken only if your doctor has advised it. If you notice any of these symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact a doctor. Do not discontinue any medications without consulting a doctor.
RitonavirLovastatin
Critical
How does the drug interact with Lopimune Tablet:
When Lovastatin is taken with Lopimune Tablet, it may increase the risk of side effects such as liver damage.

How to manage the interaction:
Taking Lopimune Tablet and Lovastatin not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. If you notice any of these symptoms like muscle pain, tenderness, or weakness fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes contact a doctor. Do not discontinue any medications without consulting a doctor.
RitonavirNimodipine
Critical
How does the drug interact with Lopimune Tablet:
Taking Nimodipine with Lopimune Tablet can increase the blood levels of Lopimune Tablet, which may lead to increased side effects.

How to manage the interaction:
Taking Nimodipine with Lopimune Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience irregular heart rhythm, swelling, and lightheadedness, contact a doctor. Do not discontinue any medications without consulting a doctor.
RitonavirTicagrelor
Critical
How does the drug interact with Lopimune Tablet:
Taking Ticagrelor with Lopimune Tablet may significantly increase the blood levels of Ticagrelor.

How to manage the interaction:
Taking Ticagrelor with Lopimune Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
RitonavirEplerenone
Critical
How does the drug interact with Lopimune Tablet:
Co-administration of Eplerenone and Lopimune Tablet may significantly increase the blood levels of Eplerenone.

How to manage the interaction:
Taking Lopimune Tablet and Eplerenone together is not recommended as it can lead to an interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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LOPINAVIR-200MG+RITONAVIR-50MGHerbal products/medicines
Moderate

Drug-Food Interactions

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LOPINAVIR-200MG+RITONAVIR-50MGHerbal products/medicines
Moderate
Common Foods to Avoid:
St. John’S Wort

How to manage the interaction:
Co-administration of Lopimune Tablet with St. John's Wort may impair virologic effectiveness (failure to meet a specific target of antiviral drug treatment) and lower the blood levels of ritonavir & lopinavir. Avoid taking St. John's Wort with Lopimune Tablet as this can lower the blood levels of ritonavir & lopinavir.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ASTEMIZOLE
  • TERFENADINE
  • TRIAZOLAM
  • MIDAZOLAM
  • QUETIAPINE
  • PIMOZIDE
  • LURASIDONE
  • SIMVASTATIN
  • LOVASTATIN
  • FUSIDIC ACID
  • SILDENAFIL
  • VARDENAFIL
  • AVANAFIL
  • CISAPRIDE
  • DRONEDARONE
  • AMIODARONE
  • DIHYDROERGOTAMINE
  • METHYLERGONOVINE
  • ERGOTAMINE
  • ERGONOVINE

Habit Forming

No

Special Advise

Certain tests are recommended while taking Lopimune Tablet to monitor the changes in levels of blood lipids and glucose.

Diet & Lifestyle Advise

  • Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
  • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injections, or drug equipment.
  • Get tested for other sexually transmitted infections such as gonorrhea or syphilis as they can make you prone to HIV infection.
  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark green, yellow, orange, and red vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry, or seafood.
  • Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with family or doing whatever makes you happy.

Lopimune Tablet Substitute

Substitutes safety advice

  • Ritocom Tablet 30's

    by Others

    ₹48.33per tablet

  • Emletra Tablet 1's

    by Others

    ₹2357.10per tablet

  • Alltera 200/50 mg Tablet 120's

    by AYUR

    ₹32.06per tablet

  • Aluvia 200 mg/50 mg Tablet 120's

    by Others

    ₹0.40per tablet

  • Aluvia 200mg/50mg Tablet 120's

    by Others

    ₹37.96per tablet

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