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  1. Home
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  3. Lorbriqua 100 mg Tablet 30's

Lorbriqua 100 mg Tablet 30's, Pack of 1 Tablet
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sureshvarma D , MPharma
48 Hrs returnable
Know More
COD available

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Whats That

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Composition :

LORLATINIB-100MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTINEOPLASTIC

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051
Other Info - LOR0672

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Sureshvarma D

Reviewed By

Sureshvarma D

MPharma

Last Updated

Jul 8, 2025 | 9:40 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Lorbriqua 100 mg Tablet contains the active substance Lorlatinib, which inhibits a type of enzyme called tyrosine kinase and triggers the death of cancer cells in patients with alterations in genes for ALK. Lorbriqua 100 mg Tablet is only given to patients whose disease is due to an alteration in the gene for ALK tyrosine kinase.

Lorlatinib belongs to the kinase inhibitor class of drugs. Lorlatinib is a drug used to treat a kind of non-small cell lung cancer (NSCLC) that has spread to other places of the body in adults. It works by preventing the malfunctioning protein from causing cancer cells to multiply.

Lorbriqua 100 mg Tablet should be stopped when a person faces a serious side effect that affects life quality. Otherwise, it would be best to keep taking Lorbriqua 100 mg Tablet until your doctor asks you to stop it.

Avoid smoking before starting the treatment while taking Lorbriqua 100 mg Tablet as smoking might alter the effectiveness of Lorbriqua 100 mg Tablet .

In elderly patients, the risk of side effects is greater. For the elderly, dose adjustment might be required, or your doctor might prescribe any other medication safe for the elderly.

You should complete the full course of Lorbriqua 100 mg Tablet as your doctor prescribes. After completing the full course of Lorbriqua 100 mg Tablet will work. It would help if you took Lorbriqua 100 mg Tablet at the right dose, right times and for the right number of days.

Detecting lung cancer in its early stages, when it is most treatable, is critical to survival. Early tumours have a cure rate of 85-90 per cent, but this depends on other factors.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

It is not known if alcohol interacts with Lorbriqua 100 mg Tablet . However, as a precautionary measure, you are recommended not to consume alcohol with the Lorbriqua 100 mg Tablet to avoid unpleasant side effects.

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Pregnancy

Unsafe

Lorbriqua 100 mg Tablet is listed as pregnancy category D. Because Lorbriqua 100 mg Tablet can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Lorbriqua 100 mg Tablet .

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Breast Feeding

Unsafe

Do not breastfeed for seven days after the last dose while taking this medicine. This is because it is unknown if the Lorbriqua 100 mg Tablet can pass into breast milk and could harm your baby.

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Driving

Caution

Lorbriqua 100 mg Tablet moderately influences the ability to drive and use machines. Caution should be exercised when driving or operating machines, as patients may experience CNS effects.

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Liver

Caution

Inform your doctor before receiving the Lorbriqua 100 mg Tablet if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your current liver conditions.

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Kidney

Caution

Inform your doctor before receiving the Lorbriqua 100 mg Tablet if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your current kidney conditions.

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Children

Unsafe

Lorbriqua 100 mg Tablet is only indicated in adults, and it is not to be given to children and adolescents.

Product Substitutes

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210868s000lbl.pdf
  2. https://www.medicines.org.uk/emc/files/pil.10632.pdf
  3. https://www.medicines.org.uk/emc/product/10632/smpc

About Lorbriqua 100 mg Tablet

Lorbriqua 100 mg Tablet belongs to the group of medicines that inhibit an enzyme called anaplastic lymphoma kinase (ALK). It is used to treat adults with advanced stages of lung cancer called non-small cell lung cancer (NSCLC). Non-small cell lung cancer is a disease in which malignant (cancer) cells form in the lung tissues. There are several types of non-small cell lung cancer. Smoking is the major risk factor for non-small cell lung cancer.

Lorbriqua 100 mg Tablet contains the active substance Lorlatinib, a medicine used to treat adults with advanced stages of a form of lung cancer called non-small cell lung cancer (NSCLC). It works by inhibiting a type of enzyme called tyrosine kinase and triggers the death of cancer cells in patients with alterations in genes for ALK. Lorbriqua 100 mg Tablet is only given to patients whose disease is due to an alteration in the gene for ALK tyrosine kinase.

Always use this medicine as your doctor has told you or per the package leaflet. You must keep to your doctor's instructions to get the maximum benefit. In some cases, you may experience common side effects such as diarrhoea, constipation, joint pain, weight gain, headache, rash, and muscle pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking Lorbriqua 100 mg Tablet if you are pregnant or breastfeeding. Lorbriqua 100 mg Tablet may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Lorbriqua 100 mg Tablet as it could lead to increased dizziness. Lorbriqua 100 mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established. Lorbriqua 100 mg Tablet is listed as pregnancy category D. Because Lorbriqua 100 mg Tablet can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Lorbriqua 100 mg Tablet . Consult your doctor if you are breastfeeding; your doctor will decide whether Lorbriqua 100 mg Tablet can be taken by breastfeeding mothers or not. Keep your doctor informed about your health condition and medicines to rule out any side effects. Lorbriqua 100 mg Tablet may affect male fertility. Talk to your doctor about fertility preservation before taking Lorbriqua 100 mg Tablet .

Uses of Lorbriqua 100 mg Tablet

Treatment of advanced stages of lung cancer called non-small cell lung cancer (NSCLC)

Medicinal Benefits Mweb

Medicinal Benefits

Lorbriqua 100 mg Tablet contains the active substance Lorlatinib, a medicine used to treat adults with advanced stages of a form of lung cancer called non-small cell lung cancer (NSCLC). Lorbriqua 100 mg Tablet is only given to patients whose disease is due to an alteration in the gene for ALK tyrosine kinase. It works by inhibiting a type of enzyme called tyrosine kinase and triggers the death of cancer cells in patients with alterations in genes for ALK.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Lorbriqua 100 mg Tablet

  • Increase in cholesterol and triglycerides
  • Limb or skin swelling
  • Double vision
  • Pain
  • Numbness
  • Unusual sensations such as burning or pins and needles, difficulty walking, or difficulty with usual activities of daily
  • Increased level of enzymes called lipase and/or amylase
  • Anaemia
  • Diarrhoea
  • Constipation
  • Pain in your joints
  • Weight gain
  • Headache
  • Rash
  • Muscle pain

Drug Warnings

Consult your doctor before taking Lorbriqua 100 mg Tablet if you are pregnant or breastfeeding. Lorbriqua 100 mg Tablet may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Lorbriqua 100 mg Tablet as it could lead to increased dizziness. Lorbriqua 100 mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established. Lorbriqua 100 mg Tablet is listed as pregnancy category D. Because Lorbriqua 100 mg Tablet can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Lorbriqua 100 mg Tablet . Consult your doctor if you are breastfeeding; your doctor will decide whether the Lorbriqua 100 mg Tablet can be taken by breastfeeding mothers or not. Keep your doctor informed about your health condition and medicines to rule out any side effects. Lorbriqua 100 mg Tablet may affect male fertility. Talk to your doctor about fertility preservation before taking Lorbriqua 100 mg Tablet .

Drug-Drug Interactions

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LorlatinibCariprazine
Severe
LorlatinibBosentan
Severe

Drug-Drug Interactions

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LorlatinibCariprazine
Severe
How does the drug interact with Lorbriqua 100 mg Tablet:
When Cariprazine is taken with Lorbriqua 100 mg Tablet, it may reduce the blood levels of cariprazine.

How to manage the interaction:
Although taking Cariprazine and Lorbriqua 100 mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you notice any unusual symptoms or if your condition worsens, make sure to contact your doctor right away. Do not stop using any medications without talking to a doctor.
LorlatinibBosentan
Severe
How does the drug interact with Lorbriqua 100 mg Tablet:
Taking Lorbriqua 100 mg Tablet with bosentan may reduce the blood levels of Lorbriqua 100 mg Tablet, decreasing its effectiveness in treating your condition.

How to manage the interaction:
Although using Bosentan and Lorbriqua 100 mg Tablet together can result in an interaction, they can be taken together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.
LorlatinibClarithromycin
Severe
How does the drug interact with Lorbriqua 100 mg Tablet:
When Lorbriqua 100 mg Tablet is taken with Clarithromycin, it can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Clarithromycin and Lorbriqua 100 mg Tablet, but it can be taken if prescribed by a doctor. If you're having any of these symptoms - seizures, hallucinations, confusion, forgetfulness, difficulty concentrating, mood disorders, depression, dizziness, lightheadedness, difficulty breathing, cough or fever, it's important to contact your doctor right away. They may be able to recommend other options that won't cause these problems when taken together. Do not discontinue any medications without first consulting your doctor.
LorlatinibEslicarbazepine
Severe
How does the drug interact with Lorbriqua 100 mg Tablet:
Taking Lorbriqua 100 mg Tablet with eslicarbazepine may reduce the blood levels of Lorbriqua 100 mg Tablet, which may make the medication less effective in treating your condition.

How to manage the interaction:
Although there is an interaction between Lorbriqua 100 mg Tablet and eslicarbazepine, they can be taken together if prescribed by a doctor. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ITRACONAZOLE
  • ERYTHROMYCIN
  • QUINIDINE
  • ALFENTANIL
  • FENTANYL
  • CICLOSPORIN
  • SIROLIMUS
  • TACROLIMUS
  • EFAVIRENZ
  • COBICISTAT
  • BUPRENORPHINE
  • DIHYDROERGOTAMINE
  • ERGOTAMINE
  • BUPROPION
  • BOCEPREVIR

Habit Forming

No

Special Advise

You will have blood tests before you start treatment and during your treatment. These tests check the level of cholesterol, triglycerides and the enzymes amylase or lipase in your blood before you start treatment with Lorbriqua 100 mg Tablet and regularly during treatment. You will have blood tests before you start treatment and during your treatment. These tests check the level of cholesterol, triglycerides and the enzymes amylase or lipase in your blood before you start treatment with Lorbriqua 100 mg Tablet and regularly during treatment.

Diet & Lifestyle Advise

  • Watch out for triggers that worsen the cough, such as smoke, foods, air-conditioning, high altitude, etc.
  • Exercise moderately. Eat healthily.
  • Follow pulmonary rehabilitation program. It includes exercise, disease education, and group therapy.
  • Quit smoking and alcohol.
  • Get ample rest.
  • Include green leafy vegetables, sweet potatoes, broccoli, tomatoes, carrots, mangoes, citrus fruits, berries, and cocoa.
  • Lean proteins such as fish, meat, and poultry are the best.
  • Hydration is important. Drink plenty of water, herbal tea, and vegetable and fruit juices.
  • Avoid processed and refined foods.

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