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Written By Divya L , PharmaD
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Manufacturer/Marketer :

Entod Pharmaceuticals Ltd

Consume Type :

Ophthalmic

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

[OPHTHALMOLOGIC AGENTS]

Country of origin

India

Manufacturer/Marketer address

Ashirwad Building, S.V.Road, Opp. Badi Masjid, Bandra(W), Mumbai-400050, India
Other Info - LOT0760

Author Details

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FAQs

Lotebra Eye Drops 5 ml contains Tobramycin and Loteprednol. Tobramycin, an antibiotic, binds to the bacteria's proteins, disrupting the cell membrane, and leading to cell death. Loteprednol, a corticosteroid, blocks prostaglandins' production (chemical messengers) that make the eye red, swollen and itchy. Collectively, Lotebra Eye Drops 5 ml helps in relieving and treating symptoms of bacterial eye infections.

If you use other eye ointments/drops along with Lotebra Eye Drops 5 ml, it is advised to maintain a gap of at least 5-10 minutes after each administration. Also, use eye drops before applying any eye ointment.

Lotebra Eye Drops 5 ml can cause a blurry vision for some time in the beginning. Avoid driving and operating machinery in such cases until you feel better. If the effect persists longer, seek medical attention.

Avoid the contact of the dropper or tip with fingers, eyes, and eyelids when you use eye ointment or eye drops. Topical eye products, when contaminated by patients with eye diseases, bacterial keratitis (an infection of the cornea) and ocular infections (eye infections) may occur, which result in vision loss.

It is advised to remove your contact lens if you are wearing it while administering Lotebra Eye Drops 5 ml. Also, remember to wash your hands before and after administering the medicine to avoid contamination.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Safe if prescribed

There is limited information on how alcohol consumption affects Lotebra Eye Drops 5 ml. Please consult your doctor before starting.

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Pregnancy

Consult your doctor

It is not known if Lotebra Eye Drops 5 ml affects pregnancy and unborn baby. Please consult your doctor if you are planning to become pregnant or already pregnant before starting Lotebra Eye Drops 5 ml.

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Breast Feeding

Consult your doctor

Please consult your doctor before starting Lotebra Eye Drops 5 ml if you are a lactating mother.

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Driving

Safe if prescribed

Lotebra Eye Drops 5 ml may cause side effects like blurry vision, affecting your driving ability. Do not drive or operate machinery in such cases. Drive only when you are alert and have clear vision.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver diseases. Your doctor will weigh the benefits and potential risks before prescribing Lotebra Eye Drops 5 ml.

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Kidney

Consult your doctor

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Lotebra Eye Drops 5 ml.

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Children

Safe if prescribed

Please consult your doctor if Lotebra Eye Drops 5 ml is to be used in children. The dose may have to be adjusted by your doctor depending upon the condition of the children's disease and age.

About Lotebra Eye Drops 5 ml

Lotebra Eye Drops 5 ml is an ophthalmic (for eye use) medication, primarily used to treat and prevent bacterial eye infections. It is effectively used to treat eye inflammation caused by allergies, shingles, severe acne, iritis (inflammation of the coloured part of the eye (iris)), uveitis (inflammation of the middle layer of the eye (uvea)), eye injury, radiation, and chemical burns. A bacterial eye infection occurs when bacteria invade any part of the eyeball or its surrounding tissues, including the cornea (clear front surface of the eye) and the conjunctiva (thin membrane lining the outer eye and inner eyelids).

Lotebra Eye Drops 5 ml contains two medicines, namely: Tobramycin (antibiotic) and Loteprednol (corticosteroid). Tobramycin belongs to a class of drugs called aminoglycoside antibiotics. It inhibits bacteria growth by interfering with protein synthesis. It binds to the bacteria's proteins, disrupting the cell membrane, and eventually leading to cell death. Loteprednol belongs to the class of corticosteroids. It blocks prostaglandins' production (chemical messengers) that make the eye red, swollen and itchy.

Your doctor will advise on how often you take Lotebra Eye Drops 5 ml based on your medical condition. Some common side effects of Lotebra Eye Drops 5 ml include blurred vision, burning/stinging sensation in the eye, and eye discomfort. These side effects do not require medical attention and gradually resolve over time.

Please do not use Lotebra Eye Drops 5 ml without consulting your doctor if you have any heart, liver and kidney diseases and allergic reactions to Lotebra Eye Drops 5 ml and its components. Avoid touching the eye dropper with bare hands or taking it closer to the eyelids while administering drops since it contaminates the dropper tip and solution. Avoid driving or operating machines since the administration of Lotebra Eye Drops 5 ml causes blurred vision for a while after using. If you are pregnant or a breastfeeding mother, please consult your doctor before using Lotebra Eye Drops 5 ml.

Uses of Lotebra Eye Drops 5 ml

Bacterial eye infections.

Medicinal Benefits Mweb

Key Benefits

Lotebra Eye Drops 5 ml treats and prevents bacterial eye infections and contains two medicines, namely: Tobramycin (antibiotic) and Loteprednol (corticosteroid). Tobramycin is an aminoglycoside antibiotic that inhibits bacteria growth by interfering with protein synthesis. It binds to the bacteria's proteins, disrupting the cell membrane, and eventually leading to cell death. Loteprednol, a corticosteroid, blocks prostaglandins' production (chemical messengers) that make the eye red, swollen and itchy. Lotebra Eye Drops 5 ml is used to prevent or treat only bacterial eye infections.

Directions for Use

Eye drops: Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops as advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.

Side Effects of Lotebra Eye Drops 5 ml

  • Blurred vision
  • Burning/stinging sensation of the eye 
  • Eye discomfort 

Drug Warnings

Before taking Lotebra Eye Drops 5 ml, let your doctor know if have a history of eye problems (glaucoma and cataract), heart, liver or kidney diseases, and allergic reactions to Lotebra Eye Drops 5 ml and its components. Therapy with ophthalmic corticosteroids should be administered cautiously in patients with a history of cataracts, glaucoma, or increased intraocular pressure (increased pressure inside the eye). It is advised to check with your doctor before using Lotebra Eye Drops 5 ml if you are pregnant or breastfeeding. Avoid driving or operating machines since the administration of Lotebra Eye Drops 5 ml may cause temporary blurred vision for a while.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Lotebra Eye Drops 5 ml:
Coadministration of cidofovir with Lotebra Eye Drops 5 ml can cause kidney problems.

How to manage the interaction:
Taking Lotebra Eye Drops 5 ml with Cidofovir is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Lotebra Eye Drops 5 ml:
Taking deferasirox with Lotebra Eye Drops 5 ml may increase the risk of kidney problems.

How to manage the interaction:
Taking Lotebra Eye Drops 5 ml with Deferasirox together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without talking to your doctor.
TobramycinDoxacurium chloride
Severe
How does the drug interact with Lotebra Eye Drops 5 ml:
Taking Lotebra Eye Drops 5 ml with doxacurium chloride can increase the risk of respiratory depression(hypoventilation).

How to manage the interaction:
Although there is a possible interaction between Lotebra Eye Drops 5 ml and Doxacurium chloride, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Lotebra Eye Drops 5 ml:
Coadministration of Lotebra Eye Drops 5 ml with Tenofovir disoproxil can increase the risk of kidney problems.

How to manage the interaction:
Taking Tenofovir disoproxil with Lotebra Eye Drops 5 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Lotebra Eye Drops 5 ml:
Taking Furosemide with Lotebra Eye Drops 5 ml can increase the risk of hearing loss and kidney problems.

How to manage the interaction:
Although there is a possible interaction between Lotebra Eye Drops 5 ml and Furosemide, you can take these medicines together if prescribed by your doctor. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Lotebra Eye Drops 5 ml:
Coadministration of Lotebra Eye Drops 5 ml with Colistin can increase the blood levels and risk of Colistin side effects.

How to manage the interaction:
Although there is a possible interaction between Colistin and Lotebra Eye Drops 5 ml, you can take these medicines together if prescribed by your doctor. However, if you experience, shortness of breath, muscle pain, dizziness, or palpitations, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Lotebra Eye Drops 5 ml:
Using Lotebra Eye Drops 5 ml together with everolimus can increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Everolimus and Lotebra Eye Drops 5 ml, you can take these medicines together if prescribed by a doctor. However, if you experience sudden weight gain, feeling out of breath, or having kidney problems. If you experience nausea, vomiting, loss of appetite, weight loss, swelling, muscle cramps, weakness, dizziness, confusion, or an irregular heartbeat contact a doctor immediately. Do not stop using any medications without a doctor's advice.
TobramycinFoscarnet
Severe
How does the drug interact with Lotebra Eye Drops 5 ml:
Combining Lotebra Eye Drops 5 ml with Foscarnet can increase the risk of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Lotebra Eye Drops 5 ml and foscarnet, but it can be taken if prescribed by a doctor. However, if you experience nausea, swelling, sudden weight gain or weight loss, severe pain in your upper stomach spreading to your back, seizures, pounding heart beats, dizziness or chest pain contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Lotebra Eye Drops 5 ml:
Using Botulinum toxin and Lotebra Eye Drops 5 ml together may increase the risk of side effects.

How to manage the interaction:
Although taking Botulinum toxin and Lotebra Eye Drops 5 ml can cause an interaction, it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience excessive muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lotebra Eye Drops 5 ml:
Using pancuronium with Lotebra Eye Drops 5 ml can increase the risk of respiratory depression(hypoventilation).

How to manage the interaction:
Although taking Pancuronium and Lotebra Eye Drops 5 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • FUROSEMIDE
  • LANSOPRAZOLE
  • SMALLPOX VACCINE

Habit Forming

No

Special Advise

  • It is advised to reach out to your doctor if the bacterial infection symptoms persist or worsen after two treatment weeks.
  • It is better to consult your ophthalmologist to rule out the possibilities of cataract, glaucoma or any damage to the optic nerves.

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Lotebra Eye Drops 5 ml.
  • Try to maintain good hygiene to keep your eyes clean and irritant-free.
  • Do not rub your eyes even though some ophthalmic drugs make your eye itchy.
  • Wash your hands thoroughly and do not touch the dropper before using drops to avoid contamination.
  • Know your allergy triggers, such as pollen, dust and other factors.

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