FLUTICASONE-0.05%W/WOther diseases of liver
How does the disease interact with Lotop Cream 10 gm:
Corticosteroids are primarily eliminated by hepatic metabolism, hence liver dysfunction may cause them to accumulate. Hepatic disease patients need to be closely watched.
How to manage the interaction:
Liver disease patients using Lotop Cream 10 gm should be monitored closely.
FLUTICASONE-0.05%W/WCushing syndrome
How does the disease interact with Lotop Cream 10 gm:
Rarely, the use of nasal and inhaled corticosteroids may cause hyperadrenocorticism or worsen its symptoms. Corticosteroid side effects can be lessened by administering them locally rather than systemically, although the dangers are still present. Drugs that are applied topically or inhaled may enter the bloodstream, especially when high concentrations are utilised. It is crucial that the lowest effective dosage be used and that the recommended dosages of the various products not be exceeded. During inhaled or nasal corticosteroid medication, the emergence of symptoms such irregular menstruation, acneiform lesions, cataracts, and cushingoid features may signify overuse.
How to manage the interaction:
The use of inhaled and nasal corticosteroids such as Lotop Cream 10 gm may rarely precipitate or aggravate conditions of hyperadrenocorticism. Hence, you are advised not to use more than the recommended dosages.
FLUTICASONE-0.05%W/WGlaucoma
How does the disease interact with Lotop Cream 10 gm:
In patients with ocular herpes simplex, pharmacologic doses of corticosteroids may raise the risk of corneal perforation. In such patients, corticosteroid therapy should be delivered with caution, both orally and inhalation.
How to manage the interaction:
Inhaled and nasal Lotop Cream 10 gm should be used with caution in patients with ocular herpes simplex (a type of viral eye infection).
FLUTICASONE-0.05%W/WOsteoporosis without pathological fracture
How does the disease interact with Lotop Cream 10 gm:
Long-term inhalation of corticosteroids may cause a decline in bone density. This effect, which has mostly been documented with high dosages (>= 800 mcg/day of beclomethasone or similar for >= 1 year), appears to be dose-related. Patients getting lesser dosages have also been shown to have lower levels of total body calcium. Patients with osteoporosis should be treated with inhaled and nasal corticosteroids over the long term with caution. It is crucial that the lowest effective dosage be used and that the recommended dosages of the various products not be exceeded.
How to manage the interaction:
Long-term therapy with inhaled and nasal corticosteroids should be used with caution in patients with osteoporosis. It is advised not to exceed more than the recommended dosages.