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  1. Home
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  3. Luprohal 22.5 Depot Combikit Injection 1's

Luprohal 22.5 Depot Combikit Injection 1's, Pack of 1
Written By ,
Reviewed By Santoshini Reddy G , M Pharmacy
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Whats That

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Composition :

LEUPROLIDE ACETATE-22.5MG

Manufacturer/Marketer :

Halsted Pharma Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

HORMONES

Country of origin

India
Other Info - LUP0408

FAQs

Luprohal 22.5 Depot Combikit Injection contains Leuprolide acetate, a synthetic hormone that helps reduce the testosterone and oestrogen hormones in men and women, respectively. This process of lowering hormone levels can decrease cancer cell growth in prostate cancer in men and shrinks endometriosis in women.

Luprohal 22.5 Depot Combikit Injection affects the hair, making it thin which further causes loss of hair. Hair reduction possibly happens due to the estrogen lowering effect of Luprohal 22.5 Depot Combikit Injection. These effects are not long-lasting and may return after some time. If you have any concerns, contact your doctor for further advice.

Luprohal 22.5 Depot Combikit Injection may cause impotence and affect fertility in men. It is advised to speak to your doctor if you plan to have a family in the future before starting Luprohal 22.5 Depot Combikit Injection.

Luprohal 22.5 Depot Combikit Injection should be used with caution in diabetic patients as it may increase the risk of high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Luprohal 22.5 Depot Combikit Injection and inform your doctor if you have diabetes before taking Luprohal 22.5 Depot Combikit Injection.

Luprohal 22.5 Depot Combikit Injection may worsen your mood disorders like depression. Hence it is advised to use Luprohal 22.5 Depot Combikit Injection only when you are free from any kind of mental problems. Please consult your doctor for more information.

Luprohal 22.5 Depot Combikit Injection may cause osteoporosis (bone thinning) due to the reduction of estrogen in the body. Regular bone density tests may help you monitor osteoporosis. Contact your doctor if you observe any sign of tendon pain or swelling while taking Luprohal 22.5 Depot Combikit Injection.

Luprohal 22.5 Depot Combikit Injection is not recommended for patients suffering from heart rhythm problems such as arrhythmia (irregular heartbeat) as it may increase the risk of cardiac disease. Therefore, inform your doctor if you have any heart problems before taking Luprohal 22.5 Depot Combikit Injection.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Luprohal 22.5 Depot Combikit Injection to avoid unpleasant side-effects. Alcohol intake, along with Luprohal 22.5 Depot Combikit Injection, may cause increased dizziness.

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Pregnancy

Unsafe

Luprohal 22.5 Depot Combikit Injection is a pregnancy category X drug. Luprohal 22.5 Depot Combikit Injection should not be used during pregnancy because it causes harm to the fetus (newborn baby). Women of childbearing potential must use an effective method of contraception while taking Luprohal 22.5 Depot Combikit Injection. Please consult your doctor if you have any concerns regarding this.

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Breast Feeding

Unsafe

Luprohal 22.5 Depot Combikit Injection should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby. It is contraindicated in breastfeeding mothers.

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Driving

Caution

Luprohal 22.5 Depot Combikit Injection causes dizziness and affects your ability to drive. Do not drive or operate machinery if you experience any unmanageable side effects with Luprohal 22.5 Depot Combikit Injection.

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Liver

Caution

If you have had a history or evidence of any liver-related diseases, please consult the doctor before taking Luprohal 22.5 Depot Combikit Injection. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Kidney

Caution

If you have had a history or evidence of any kidney-related diseases, please consult the doctor before taking Luprohal 22.5 Depot Combikit Injection. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Children

Caution

Luprohal 22.5 Depot Combikit Injection is not recommended in children younger than two years of age and should be used with caution and only if absolutely warranted in children under 12.

Reference

  1. https://www.drugs.com/mtm/leuprolide.html
  2. https://www.medicines.org.uk/emc/files/pil.4651.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020517s036_019732s041lbl.pdf

About Luprohal 22.5 Depot Combikit Injection

Luprohal 22.5 Depot Combikit Injection belongs to the class of medicines called gonadotropin-releasing hormone (GnRH) agonists primarily used to treat prostate cancer and endometriosis. Additionally, it is also used to treat precocious puberty (early puberty) in children. Luprohal 22.5 Depot Combikit Injection is used in combination with other medicines to treat anaemia caused by uterine fibroids.

Luprohal 22.5 Depot Combikit Injection contains Leuprolide acetate, which is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. It works by inhibiting the synthesis of the natural male hormone, testosterone in men and oestrogen in women. This process of lowering hormone levels can decrease cancer cell growth in prostate cancer and helps treat endometriosis.

Luprohal 22.5 Depot Combikit Injection will be administered by a healthcare professional. The common side effects of Luprohal 22.5 Depot Combikit Injection include hot flashes, decreased sexual interest, dizziness, headache, nausea, vomiting, diarrhoea, upset stomach and injection site reaction. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Avoid taking Luprohal 22.5 Depot Combikit Injection if you are pregnant or breastfeeding. Both women and men using Luprohal 22.5 Depot Combikit Injection should use effective contraception. Luprohal 22.5 Depot Combikit Injection may affect fertility, hence discuss with your doctor if you have any plans to start a family in the future. Luprohal 22.5 Depot Combikit Injection is not recommended for children below two years of age. Luprohal 22.5 Depot Combikit Injection may cause dizziness, hence drive only if you are alert.

Uses of Luprohal 22.5 Depot Combikit Injection

Prostate cancer, Endometriosis, Precocious puberty

Medicinal Benefits Mweb

Medicinal Benefits

Luprohal 22.5 Depot Combikit Injection contains Leuprolide acetate, a gonadotropin-releasing hormone (GnRH) agonist. It treats prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children. Luprohal 22.5 Depot Combikit Injection is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. Luprohal 22.5 Depot Combikit Injection works by lowering testosterone levels in men that help stop the growth of cancer cells in prostate cancer. Luprohal 22.5 Depot Combikit Injection reduces oestrogen (a hormone required for the development and regulation of the female reproductive system and secondary sexual characteristics) levels in women, thus helping in endometriosis.

Directions for Use

Luprohal 22.5 Depot Combikit Injection will be administered by a healthcare professional. Do not self-administer.

Side Effects of Luprohal 22.5 Depot Combikit Injection

  • Weight changes
  • Hot flushes
  • Muscle weakness
  • Bone Pain
  • Loss of interest in sexual intercourse
  • Tiredness
  • Difficulty sleeping
  • Headaches
  • Nausea
  • Breast tenderness
  • Changes in breast size
  • Mood swings
  • Abdominal pain

Drug Warnings

If you are allergic to Luprohal 22.5 Depot Combikit Injection or any other medicines, please tell your doctor. Luprohal 22.5 Depot Combikit Injection is not indicated for use in pregnancy and breastfeeding women. If you are using Luprohal 22.5 Depot Combikit Injection, make sure to use reliable forms of contraception. Luprohal 22.5 Depot Combikit Injection may also affect fertility in men, hence discuss with your doctor if you have any plans to start a family in the future. Luprohal 22.5 Depot Combikit Injection is not recommended for children younger than two years of age. If you have a seizure or unusual changes in mood or behaviour, inform your doctor immediately. Before starting Luprohal 22.5 Depot Combikit Injection, let your doctor know if you have liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels. Luprohal 22.5 Depot Combikit Injection may cause QT prolongation (heart muscle takes longer than normal to recharge between beats) and may affect heart rhythm, hence heart patients should be cautious while taking Luprohal 22.5 Depot Combikit Injection. Luprohal 22.5 Depot Combikit Injection can make you feel dizzy and affects your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused.

Drug-Drug Interactions Checker List

  • QUINIDINE
  • PROCAINAMIDE
  • DISOPYRAMIDE
  • AMIODARONE
  • SOTALOL
  • DEXAMETHASONE
  • METHYLPREDNISOLONE
  • MOXIFLOXACIN
  • METHADONE
  • CITALOPRAM
  • ESCITALOPRAM
  • FLUOXETINE
  • SERTRALINE
  • PAROXETINE

Habit Forming

No

Special Advise

  • Your doctor may advise liver function tests to monitor your liver health since Luprohal 22.5 Depot Combikit Injection may cause increased liver enzymes (alanine aminotransferase, serum aspartate and serum transaminases).
  • Luprohal 22.5 Depot Combikit Injection may cause increased serum glucose levels (hyperglycaemia), hence inform your doctor if you have diabetes before starting Luprohal 22.5 Depot Combikit Injection.
  • Your doctor may advise blood tests, electrolyte levels and regular examinations of the prostate.

  • It is advised to get an electrocardiogram (ECG) done timely to monitor your heart health.

Diet & Lifestyle Advise

  • Maintain a fibre-rich diet and include fruits, vegetables and whole grains.
  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk and dairy products.
  • Exercise regularly to lose weight as obesity is also considered a risk factor for prostate cancer.
  • Eat at regular intervals.
  • Opt for a diet rich in whole grains, fruits, vegetables, and low-fat dairy products.

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