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Written By ,
Reviewed By Hari Kumar , MBBS
48 Hrs returnable
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

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Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, India.
Other Info - MAC0351

FAQs

Macdaxa 110mg Capsule is a thrombin inhibitor. The inhibition of thrombin, reduces the formation of blood-clotting material fibrin, thereby leading to fewer clots and aiding the free flow of blood.

No, you are not recommended to stop taking Macdaxa 110mg Capsule without consulting your doctor as it may worsen the condition. Therefore, take Macdaxa 110mg Capsule for as long as your doctor has prescribed it.

Please consult your doctor if you are due to undergo surgery. The doctor might ask you to stop taking Macdaxa 110mg Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery.

Taking Macdaxa 110mg Capsule during pregnancy may cause bleeding in the mother or the newborn baby. However, please consult your doctor if you are planning to become pregnant or already pregnant before starting Macdaxa 110mg Capsule .

Macdaxa 110mg Capsule may increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails, or using sharp objects. Inform your doctor immediately if you notice any abnormal staining or bleeding.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Macdaxa 110mg Capsule as it may increase the risk of bleeding.

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Pregnancy

Caution

Please consult your doctor if you are planning to become pregnant or already pregnant before starting Macdaxa 110mg Capsule . Your doctor will prescribe Macdaxa 110mg Capsule only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Macdaxa 110mg Capsule . Consult your doctor if you have nay concerns.

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Driving

Safe if prescribed

Macdaxa 110mg Capsule usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Macdaxa 110mg Capsule . However, it is not recommended in patients with severe liver diseases.

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Kidney

Caution

Let your doctor know if you have/had kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Macdaxa 110mg Capsule . However, it is not recommended in patients with severe kidney diseases.

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Children

Caution

Macdaxa 110mg Capsule is not recommended for children below the age of 18 years as the safety and efficacy of Macdaxa 110mg Capsule have not been established in children.

About Macdaxa 110mg Capsule

Macdaxa 110mg Capsule belongs to a class of drugs known as anticoagulants or blood thinners used to prevent and treat the risk of stroke, heart attack in patients with atrial fibrillation (irregular heart rhythm) by reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), and to reduce the risk of clots in people who have undergone knee or hip replacement surgeries. 

Macdaxa 110mg Capsule contains Dabigatran etexilate that works by inhibiting the production of clotting factor Xa, also called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation. It makes the blood flow easily through the veins making it less likely to form a serious blood clot. Thus, Macdaxa 110mg Capsule helps prevent blood clots thereby reducing the risk of heart attack/stroke.

Take Macdaxa 110mg Capsule as prescribed by your doctor. You are advised to take Macdaxa 110mg Capsule for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience bleeding, anaemia (low number of red blood cells), nausea, stomach pain, and vomiting. Most of these side effects of Macdaxa 110mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to Macdaxa 110mg Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Macdaxa 110mg Capsule . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Macdaxa 110mg Capsule . Try not to stop taking this medicine on your own. Discontinuing Macdaxa 110mg Capsule may worsen your condition and increase the risk of heart attack, and stroke.

Uses of Macdaxa 110mg Capsule

Prevention of blood clot formation, deep vein thrombosis, pulmonary embolism.

Medicinal Benefits Mweb

Medicinal Benefits

Macdaxa 110mg Capsule belongs to a class of drugs known as anticoagulants or blood thinners. Macdaxa 110mg Capsule is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation. Besides this, it also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. Macdaxa 110mg Capsule works by stopping the action of clotting factor (thrombin). This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

Directions for Use

Take Macdaxa 110mg Capsule exactly as your doctor has prescribed it. Swallow it as a whole with water; do not crush or chew it.

Side Effects of Macdaxa 110mg Capsule

  • Stomach pain
  • Vomiting
  • Bleeding
  • Anaemia (low number of red blood cells)
  • Nausea
  • Diarrhoea

Drug Warnings

If you are known to be allergic to Macdaxa 110mg Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Macdaxa 110mg Capsule . Macdaxa 110mg Capsule is not recommended for children less than 18 years of age as the Safety and effectiveness have not been established. If you have an artificial heart valve, stomach ulcer, kidney/liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Macdaxa 110mg Capsule . You should inform the doctor that you are taking Macdaxa 110mg Capsule if you are due to undergo surgery. Avoid consumption of alcohol while taking Macdaxa 110mg Capsule as it may increase the risk of stomach bleeding.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Macdaxa 110mg Capsule:
When Mifepristone is taken with Macdaxa 110mg Capsule, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Mifepristone with Macdaxa 110mg Capsule is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
How does the drug interact with Macdaxa 110mg Capsule:
Using dabigatran together with dalteparin may increase the risk of bleeding.

How to manage the interaction:
Although taking Dalteparin with Macdaxa 110mg Capsule may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Macdaxa 110mg Capsule:
Taking Flurbiprofen with Macdaxa 110mg Capsule can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although taking Flurbiprofen and Macdaxa 110mg Capsule together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you experience bleeding, feeling dizzy or lightheaded, dark or sticky stools, throwing up blood, severe headache, or feeling weak contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Macdaxa 110mg Capsule:
Macdaxa 110mg Capsule can make Enoxaparin more effective at preventing blood clotting, this can increase the risk or severity of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Enoxaparin and Macdaxa 110mg Capsule, but it can be taken if prescribed by a doctor. If you notice any of these signs, it's important to contact a doctor right away: bleeding that doesn't stop, blood in your stool, dizziness, dark or bloody stools, headache, weakness, or vomiting blood. Do not stop using any medications without talking to a doctor.
How does the drug interact with Macdaxa 110mg Capsule:
Taking Clopidogrel with Dabigatran may increase the risk of bleeding.

How to manage the interaction:
Although there may be an interaction between clopidogrel and Apixaban, they can be taken together if advised by your doctor. However, consult your doctor immediately if you experience any unusual bleeding, dizziness or lightheadedness, red or black, sticky stools, or headaches. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Macdaxa 110mg Capsule:
Concomitant use of diclofenac with dabigatran may increase the risk of stomach bleeding.

How to manage the interaction:
Taking diclofenac with dabigatran together possibly results in an interaction, it can be taken if your doctor has advised it. You should consult a doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, light headedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Macdaxa 110mg Capsule:
Combining Macdaxa 110mg Capsule with Deferasirox can increase the risk of gastrointestinal bleeding.

How to manage the interaction:
Co-administration of Macdaxa 110mg Capsule with Deferasirox can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Macdaxa 110mg Capsule:
Coadministration of Mefenamic acid with Dabigatran can increase the risk or severity of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Mefenamic acid with Macdaxa 110mg Capsule together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Macdaxa 110mg Capsule:
Co-administration of dabigatron etexilate with cilostazol can increase the risk or severity of bleeding.

How to manage the interaction:
Taking dabigatron etexilate with cilostazol together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as unusual bleeding or bruising, dizziness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Macdaxa 110mg Capsule:
Using Indomethacin with Macdaxa 110mg Capsule can increase the risk of bleeding.

How to manage the interaction:
Taking Indometacin with Macdaxa 110mg Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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DABIGATRAN ETEXILATE-110MGHerbal products/medicines

Drug-Food Interactions

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DABIGATRAN ETEXILATE-110MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill

How to manage the interaction:
Herbs and supplements may interact with Macdaxa 110mg Capsule. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Macdaxa 110mg Capsule treatment.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • WARFARIN
  • PHENPROCOUMON
  • ACENOCOUMAROL
  • HEPARIN
  • CLOPIDOGREL
  • PRASUGREL
  • TICAGRELOR
  • RIVAROXABAN
  • AMIODARONE
  • DRONEDARONE
  • QUINIDINE
  • VERAPAMIL
  • ITRACONAZOLE
  • KETOCONAZOLE
  • TACROLIMUS
  • CYCLOSPORINE
  • INDINAVIR
  • RITONAVIR
  • RIFAMPICIN
  • CLARITHROMYCIN
  • GLECAPREVIR
  • PIBRENTASVIR
  • IBUPROFEN
  • DICLOFENAC
  • PHENYTOIN
  • CARBAMAZEPINE

Habit Forming

No

Special Advise

  • You should have regular platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR), and the INR (international normalized ratio) to analyze your blood clotting time.
  • In case you miss a dose of Macdaxa 110mg Capsule , take it as soon as possible. However, if it is too close to the next dose, revert to the original schedule.

Diet & Lifestyle Advise

  • Keep your cholesterol and triglyceride levels under control.
  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, vegetables.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.

Macdaxa 110mg Capsule Substitute

Always consult your doctor before taking any new medications and supplements

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