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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

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Composition :

LETROZOLE-5MG

Manufacturer/Marketer :

Gynofem Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

CHEMOTHERAPY

Country of origin

India
Other Info - MAC0506

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Macova 5 mg Tablet works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme Macova 5 mg Tablet prevents the growth of cancer cells. Thereby, Macova 5 mg Tablet helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

Macova 5 mg Tablet causes dizziness and drowsiness. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.

High blood pressure could be a side-effect of Macova 5 mg Tablet. Regularly monitor blood pressure levels while taking Macova 5 mg Tablet. Consult your doctor if you regularly notice high blood pressure levels.

Do not stop taking Macova 5 mg Tablet on your own. You are advised to take Macova 5 mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Macova 5 mg Tablet.

Macova 5 mg Tablet may cause osteoporosis (bone thinning) due to the reduction of estrogen in the body. Regular bone density tests may help you monitor osteoporosis. Contact your doctor if you observe any sign of tendon pain or swelling while taking Macova 5 mg Tablet.

Macova 5 mg Tablet may cause weight gain due to an increase in appetite. Eat a healthy diet and exercise regularly to maintain proper weight.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Macova 5 mg Tablet to avoid unpleasant side effects. Alcohol intake, along with Macova 5 mg Tablet, may cause increased drowsiness.

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Pregnancy

Unsafe

Macova 5 mg Tablet is pregnancy category D medicine so, should not be taken during pregnancy.

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Breast Feeding

Unsafe

Macova 5 mg Tablet should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby.

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Driving

Caution

Macova 5 mg Tablet may cause dizziness and drowsiness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Safe if prescribed

It is safe to take Macova 5 mg Tablet if prescribed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Safe if prescribed

It is safe to take Macova 5 mg Tablet if prescribed. Please consult your doctor if you have kidney impairment or any concerns regarding this. No dosage adjustment is required for kidney patients with creatinine clearance greater than 10 mL/min.

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Children

Unsafe

Macova 5 mg Tablet should not be used by children, as the efficacy and safety have not been established.

About Macova 5 mg Tablet

Macova 5 mg Tablet belongs to the group of anti-cancer medicines called aromatase inhibitors used to treat breast cancer in women who have gone through menopause (cessation of menses periods). Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen.
 
Macova 5 mg Tablet contains 'Letrozole' that works by blocking the aromatase enzyme, which is involved in the production of the estrogen hormone. The cancer cells require estrogen for their growth. Hence, by blocking the aromatase enzyme, Macova 5 mg Tablet prevents the growth of cancer cells. Thereby Macova 5 mg Tablet helps in preventing or stopping the growth of spreading the tumours (cancer cells) to other body parts.

You are advised to take Macova 5 mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, Macova 5 mg Tablet may cause certain common side-effects such as hypercholesterolemia (increased cholesterol levels), tiredness, weakness, increased sweating, feeling unwell, pain in joints, and hot flushes (feeling of warmth). Do not be reluctant to talk with your doctor if you experience any of these side-effects persistently.
 
Avoid taking Macova 5 mg Tablet if you are pregnant or breastfeeding. Macova 5 mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Macova 5 mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Macova 5 mg Tablet as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications to rule out any side-effects.

Uses of Macova 5 mg Tablet

Breast cancer

Medicinal Benefits Mweb

Medicinal Benefits

Macova 5 mg Tablet belongs to the group of anti-cancer medicines called aromatase inhibitors. Macova 5 mg Tablet is used to treat breast cancer in women who have gone through menopause (cessation of periods). Macova 5 mg Tablet works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme Macova 5 mg Tablet prevents the growth of cancer cells. Thereby, Macova 5 mg Tablet helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

Directions for Use

Take Macova 5 mg Tablet with or without food. Swallow Macova 5 mg Tablet as a whole with a glass of water; do not chew or break it. Take Macova 5 mg Tablet at the same time every day.

Side Effects of Macova 5 mg Tablet

  • Hypercholesterolemia (increased cholesterol levels)
  • Tiredness
  • Weakness
  • Increased sweating
  • Feeling unwell
  • Pain in joints
  • Hot flushes (feeling of warmth)

Drug Warnings

Do not take Macova 5 mg Tablet if you are allergic to any of its contents, if you have not yet gone through menopause (still get your periods). Talk to your doctor before taking Macova 5 mg Tablet if you have osteoporosis (thinning of bones), bone fractures, severe liver or kidney disease. Macova 5 mg Tablet may cause inflammation in tendons or tendon injury; contact your doctor if you observe any sign of tendon pain or swelling while taking Macova 5 mg Tablet. Avoid taking Macova 5 mg Tablet if you are pregnant or breastfeeding. Macova 5 mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Macova 5 mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Macova 5 mg Tablet as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications before taking Macova 5 mg Tablet to rule out any side-effects. 

Drug-Drug Interactions

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LetrozoleCitalopram
Severe
LetrozoleConjugated Estrogens
Severe

Drug-Drug Interactions

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LetrozoleCitalopram
Severe
How does the drug interact with Macova 5 mg Tablet:
Co-administration of Macova 5 mg Tablet and Citalopram may raise the risk of a serious irregular heartbeat.

How to manage the interaction:
Although taking Macova 5 mg Tablet and Citalopram together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, rapid heartbeat, you should consult a doctor. Do not discontinue any medications without a doctor's advice.
LetrozoleConjugated Estrogens
Severe
How does the drug interact with Macova 5 mg Tablet:
Coadministration of Conjugated estrogens with Macova 5 mg Tablet may reduce the effect of Macova 5 mg Tablet.

How to manage the interaction:
Although taking Conjugated estrogen and Macova 5 mg Tablet together can result in an interaction, it can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
LetrozoleEthinylestradiol
Severe
How does the drug interact with Macova 5 mg Tablet:
When taken together ethinyl estradiol may interfere with Macova 5 mg Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
Although taking Macova 5 mg Tablet and ethinylestradiol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.
LetrozoleEstrone
Severe
How does the drug interact with Macova 5 mg Tablet:
When taken together Macova 5 mg Tablet's function could be blocked by estrone, which would reduce its ability to effectively treat your illness.

How to manage the interaction:
Although taking Macova 5 mg Tablet and estrone together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
LetrozoleThalidomide
Severe
How does the drug interact with Macova 5 mg Tablet:
Coadministration of thalidomide and Macova 5 mg Tablet may increase the risk of blood clots.

How to manage the interaction:
Although taking Macova 5 mg Tablet and thalidomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, consult a doctor. Do not discontinue any medications without a doctor's advice.
LetrozoleEstramustine
Severe
How does the drug interact with Macova 5 mg Tablet:
when taken together Macova 5 mg Tablet's function could be blocked by estramustine, which would reduce its ability to effectively treat your illness.

How to manage the interaction:
Although taking Macova 5 mg Tablet and estramustine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
LetrozoleDesogestrel
Severe
How does the drug interact with Macova 5 mg Tablet:
Co-administration of Desogestrel together with Macova 5 mg Tablet may decrease the effects of Macova 5 mg Tablet.

How to manage the interaction:
Although taking Macova 5 mg Tablet and Desogestrel together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any medications.
LetrozoleEstradiol
Severe
How does the drug interact with Macova 5 mg Tablet:
Macova 5 mg Tablet may have a negative effect when used with Estradiol, making it less effective in treating your disease.

How to manage the interaction:
Although taking Macova 5 mg Tablet and estradiol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
LetrozoleDiethylstilbestrol
Severe
How does the drug interact with Macova 5 mg Tablet:
Co-administration of Macova 5 mg Tablet may have an effect when used with Diethylstilbestrol, making it less effective in treating your disease.

How to manage the interaction:
Although taking Macova 5 mg Tablet and diethylstilbestrol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CITALOPRAM
  • ESCITALOPRAM
  • TAMOXIFEN

Habit Forming

No

Special Advise

  • Your doctor may advise you to regularly measure bone density before, during and after the treatment as Macova 5 mg Tablet may cause bone thinning due to reduction of estrogens in the body.
  • Macova 5 mg Tablet should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Macova 5 mg Tablet.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Macova 5 mg Tablet Substitute

Substitutes safety advice
  • Stimucor 5 Tablet 5's

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    67.32per tablet
  • Oneova 5mg Tablet 5's

    by AYUR

    61.20per tablet
  • Letoduz 5 Tablet 5's

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    37.26per tablet
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