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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

RAMIPRIL-1.25MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ACE INHIBITORS

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - MAC0039

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

MACPRIL 1.25MG TABLET belongs to the group of medicines called Angiotensin Converting Enzyme (ACE) Inhibitors that works by lowering the body’s production of substances that could increase the blood pressure. MACPRIL 1.25MG TABLET relaxes and widens the blood vessels making it easier for the heart to pump blood to all parts of the body. This helps in lowering the blood pressure and the risk of having a heart attack or stroke.

If you are diabetic you should monitor your blood glucose levels often especially in the first few weeks because MACPRIL 1.25MG TABLET can lower glucose/sugar levels in blood. However, please consult your doctor before taking MACPRIL 1.25MG TABLET if you are diabetic.

Please do not stop taking MACPRIL 1.25MG TABLET without consulting your doctor on your own as it may lead to rise in blood pressure. Continue taking MACPRIL 1.25MG TABLET for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking MACPRIL 1.25MG TABLET.

Orthostatic hypotension could be a side-effect of MACPRIL 1.25MG TABLET, especially in people who are dehydrated. Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking MACPRIL 1.25MG TABLET are advised to regularly monitor their blood pressure levels to avoid such unpleasant events.

Do not overdose on MACPRIL 1.25MG TABLET or any medicine as it could lead to very unpleasant side-effects. Take MACPRIL 1.25MG TABLET only as prescribed by your doctor. Overdose of MACPRIL 1.25MG TABLET can cause increased heartbeat, dizziness and sleepiness. Rush to your nearest doctor as early as possible if you have overdosed on MACPRIL 1.25MG TABLET.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking MACPRIL 1.25MG TABLET to avoid unpleasant side-effects. Alcohol intake might interfere with the working of MACPRIL 1.25MG TABLET. Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Unsafe

It is not recommended to take MACPRIL 1.25MG TABLET while you are pregnant. Please consult your doctor if you have any concerns regarding this, your doctor will decide whether MACPRIL 1.25MG TABLET can be given to pregnant women or not.

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Breast Feeding

Unsafe

It is not recommended to take MACPRIL 1.25MG TABLET while you are breastfeeding. Please consult your doctor if you have any concerns regarding this, your doctor will decide whether MACPRIL 1.25MG TABLET can be given to breast-feeding mothers or not.

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Driving

Caution

MACPRIL 1.25MG TABLET may cause dizziness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Dose adjustment may be needed. MACPRIL 1.25MG TABLET should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. MACPRIL 1.25MG TABLET should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have any concerns regarding this.

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Children

Unsafe

MACPRIL 1.25MG TABLET should not be used by children as the efficacy and safety has not been established.

About MACPRIL 1.25MG TABLET

MACPRIL 1.25MG TABLET belongs to the group of blood pressure-lowering medications called 'Angiotensin-Converting Enzyme (ACE) Inhibitors' primarily used to treat high blood pressure (hypertension) and reduce the risk of having a heart attack, stroke or heart failure. High blood pressure is a chronic condition in which the pressure in the blood vessels is high.

MACPRIL 1.25MG TABLET contains 'Ramipril' that relaxes and widens the blood vessels making it easier for the heart to pump blood to all parts of the body thereby lowering the raised blood pressure and reducing the risk of having a heart attack, stroke or heart failure.

Take MACPRIL 1.25MG TABLET with or without food. Do not chew, crush, or break MACPRIL 1.25MG TABLET, swallow it as a whole with a glass of water. Take MACPRIL 1.25MG TABLET at the same time every day. In some cases, MACPRIL 1.25MG TABLET may cause common side-effects like headache, dizziness, fatigue, and cough. Most of these side-effects do not require medical attention and will resolve gradually over time. Talk to your doctor if you experience these side-effects persistently.

Try not to stop taking it on your own as it may cause a sudden increase the blood pressure, chest pain or heart attack. Regular monitoring of blood pressure, electrolyte levels and kidney functioning is advised while taking MACPRIL 1.25MG TABLET. Avoid taking MACPRIL 1.25MG TABLET if you are pregnant or breastfeeding. Talk to your doctor, he/she may prescribe you alternate medicine. MACPRIL 1.25MG TABLET is not recommended for children below 18 years of age as efficacy and safety have not been established.

Uses of MACPRIL 1.25MG TABLET

Hypertension (high blood pressure), Prevention of heart attack, stroke, and heart failure.

Medicinal Benefits Mweb

Medicinal Benefits

MACPRIL 1.25MG TABLET is used alone or in combination with other medicines to treat high blood pressure. MACPRIL 1.25MG TABLET relaxes and widens the blood vessels making it easier for the heart to pump blood to all parts of the body. This helps in lowering blood pressure and the risk of having a heart attack or stroke. MACPRIL 1.25MG TABLET helps in reducing both standing and lying down blood pressure without any orthostatic effect (sudden decrease in blood pressure which might occur when a person stands up suddenly). However, when dehydrated MACPRIL 1.25MG TABLET may show an orthostatic effect. Continued usage of MACPRIL 1.25MG TABLET helps in decreasing the severity of heart failure, rate of hospitalization and symptoms such as weakness and shortness of breath.

Directions for Use

Swallow MACPRIL 1.25MG TABLET with a glass of water as a whole. Do not crush, break or chew it. MACPRIL 1.25MG TABLET can be taken with or without food at the same time daily for best results. Take MACPRIL 1.25MG TABLET exactly as prescribed by your doctor. Based on your medical condition your doctor will advise for how long you need to take MACPRIL 1.25MG TABLET.

Side Effects of MACPRIL 1.25MG TABLET

  • Headache
  • Nausea
  • Dizziness
  • Weakness
  • Low blood pressure
  • Inflammation of the sinus (sinusitis)
  • Shortness of breath
  • Stomach pain
  • Diarrhoea
  • Indigestion

Drug Warnings

Do not take MACPRIL 1.25MG TABLET if you are allergic to any of its contents. Talk to your doctor if you have heart, kidney or liver problems. MACPRIL 1.25MG TABLET may sometimes cause a decrease in blood pressure than normal, especially in dehydrated people, who are taking diuretics (medicines to treat oedema) and have low levels of sodium. Avoid taking MACPRIL 1.25MG TABLET if you are pregnant or breastfeeding. Talk to your doctor, he/she may prescribe you alternate medicine. MACPRIL 1.25MG TABLET is not recommended for children below 18 years of age as efficacy and safety have not been established. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side effects. Consult your doctor if you have lost a lot of body fluids through vomiting, diarrhoea or sweating more than normal or if you are taking low water tablets to treat oedema (diuretics), or if you undergo dialysis. Inform your doctor that you are taking MACPRIL 1.25MG TABLET if you are due to undergo any surgery or dental procedure; your doctor may advise you to stop taking MACPRIL 1.25MG TABLET one day before receiving an anaesthetic to undergo any surgery or dental procedure.

Drug-Drug Interactions

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RamiprilAliskiren
Critical
RamiprilAmiloride
Severe

Drug-Drug Interactions

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RamiprilAliskiren
Critical
How does the drug interact with Macpril 1.25mg Tablet:
Taking aliskiren together with Macpril 1.25mg Tablet may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm.

How to manage the interaction:
Taking Macpril 1.25mg Tablet with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, consult your doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. It is advised to reduce the intake of foods high in potassium, including tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes. Do not discontinue any medications without a doctor's advice.
RamiprilAmiloride
Severe
How does the drug interact with Macpril 1.25mg Tablet:
Taking Macpril 1.25mg Tablet and amiloride together may increase the levels of potassium in your blood.

How to manage the interaction:
Although taking amiloride along with Macpril 1.25mg Tablet can result in an interaction, they can be taken together if prescribed by a doctor. However, consult the doctor if you feel weakness, confusion, numbness or tingling, and uneven heartbeats. Do not stop taking any medication without consulting a doctor.
RamiprilSpironolactone
Severe
How does the drug interact with Macpril 1.25mg Tablet:
Using Macpril 1.25mg Tablet together with spironolactone may cause hyperkalemia (increase the levels of potassium in your blood).

How to manage the interaction:
Although taking spironolactone and captopril together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as weakness, confusion, numbness or tingling, and uneven heartbeat. Do not stop using any medications without consulting doctor.
RamiprilOlmesartan medoxomil
Severe
How does the drug interact with Macpril 1.25mg Tablet:
Taking Macpril 1.25mg Tablet together with olmesartan may increase the risk of side effects (blood pressure, kidney function impairment, and a condition called Hyperkalemia - high blood potassium).

How to manage the interaction:
Although taking olmesartan medoxomil with Macpril 1.25mg Tablet may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
RamiprilAllopurinol
Severe
How does the drug interact with Macpril 1.25mg Tablet:
Co-administration of Allopurinol with Macpril 1.25mg Tablet may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Allopurinol and Macpril 1.25mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also, let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not discontinue the medication without consulting a doctor.
RamiprilEprosartan
Severe
How does the drug interact with Macpril 1.25mg Tablet:
Coadministration of Macpril 1.25mg Tablet together with eprosartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Macpril 1.25mg Tablet together with Eprosartan can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. Do not stop taking any medication without consulting your doctor.
RamiprilTrimethoprim
Severe
How does the drug interact with Macpril 1.25mg Tablet:
Taking Macpril 1.25mg Tablet with Trimethoprim can increase the potassium levels in the blood, increasing the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between Macpril 1.25mg Tablet and trimethoprim, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience weakness, confusion, numbness or tingling, and uneven heartbeats. Do not stop taking any medication without consulting your doctor.
RamiprilTizanidine
Severe
How does the drug interact with Macpril 1.25mg Tablet:
Taking Macpril 1.25mg Tablet with Tizanidine may have additive effects in lowering your blood pressure

How to manage the interaction:
Although taking Macpril 1.25mg Tablet together with Tizanidine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you feel headache, dizziness, lightheadedness, fainting, and changes in pulse or heart rate. If you have the above symptoms, avoid tasks requiring attentiveness, such as driving or using dangerous machinery. Be careful when you stand up from a sitting or lying position. Do not stop taking any medication without consulting your doctor.
RamiprilAzilsartan medoxomil
Severe
How does the drug interact with Macpril 1.25mg Tablet:
Taking Azilsartan medoxomil with Macpril 1.25mg Tablet may cause low blood pressure, kidney function impairment, and increased potassium levels in the blood.

How to manage the interaction:
Although taking Macpril 1.25mg Tablet together with Azilsartan medoxomil can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, weakness, confusion, tingling in the hands and feet, or palpitations. Do not discontinue any medications without a doctor's advice.
RamiprilPotassium acetate
Severe
How does the drug interact with Macpril 1.25mg Tablet:
Taking Macpril 1.25mg Tablet with potassium acetate may significantly increase potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm

How to manage the interaction:
Although there is a interaction between Macpril 1.25mg Tablet and Potassium acetate, but it can be taken if prescribed by a doctor. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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RAMIPRIL-1.25MGPotassium rich foods
Moderate

Drug-Food Interactions

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RAMIPRIL-1.25MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consuming potassium-rich foods while using Macpril 1.25mg Tablet may increase the potassium levels in your blood. It is recommended to avoid potassium-rich foods while using Macpril 1.25mg Tablet. If you experience a fast heartbeat, shortness of breath, chest pain, nausea, or vomiting, consult your doctor immediately.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • PREGABALIN
  • ASPIRIN
  • NAPROXEN
  • IBUPROFEN
  • SILDENAFIL
  • ALLOPURINOL
  • SITAGLIPTIN
  • METFORMIN
  • INSULIN
  • FUROSEMIDE
  • PREDNISOLONE

Habit Forming

No

Special Advise

  • Get up slowly while rising from lying or sitting position as MACPRIL 1.25MG TABLET may cause dizziness.
  • Avoid consuming food rich in potassium such as banana, broccoli, almonds, avocado, and potassium supplements.
  • Regular monitoring of blood pressure, electrolyte levels and kidney functioning is advised while taking MACPRIL 1.25MG TABLET.

Diet & Lifestyle Advise

  • You are advised to consume low salt and low-fat diet while taking MACPRIL 1.25MG TABLET.
  • Regular exercise is also recommended to complement treatment with MACPRIL 1.25MG TABLET.
  • Eat a diet rich in whole grains, vegetables, and fruits.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Managing stress with meditation, yoga, and massage would also help treat high blood pressure.

MACPRIL 1.25MG TABLET Substitute

Substitutes safety advice
  • Cardace 1.25 mg Tablet 15's

    by AYUR

    6.36per tablet
  • Ramistar 1.25 mg Tablet 15's

    by AYUR

    7.38per tablet
  • Ramipres-1.25 Tablet 10's

    by Others

    6.21per tablet
  • Cardace 1.25 mg Tablet 10's

    by AYUR

    5.81per tablet
  • Car-Race-1.25Mg Tablet 10'S

    by AYUR

    3.46per tablet
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