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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer :

Matias Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANTIPSYCHOTICS

Country of origin

India
Other Info - MA42770

Author Details

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FAQs

Matium SR 450 Tablet helps to treat mental disorders by increasing the activity of chemical messengers in the brain; thereby, suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood.

Matium SR 450 Tablet is not recommended for hypothyroid (underactive thyroid gland) patients as it may increase the risk of low levels of thyroid hormone. Therefore, if you have hypothyroidism, please inform your doctor before taking Matium SR 450 Tablet.

Matium SR 450 Tablet may cause weight gain but it is not necessary for everyone taking Matium SR 450 Tablet to experience this side effect. However, in order to avoid gaining weight while taking Matium SR 450 Tablet, you are advised to do regular exercise and avoid high-calorie drinks. Instead take non-alcoholic drinks, herbal tea and lemon water.

It is advised to inform your doctor if you are planning or had weight loss surgery as the dose may be adjusted accordingly based on lithium levels in blood.

Matium SR 450 Tablet may cause dehydration especially if you have low sodium levels in the body or consume too much alcohol. However, if you notice dark, strong-smelling urine or a decrease in urination, it indicates that you are dehydrated, and this may affect lithium levels in the blood. Therefore, you are recommended to drink plenty of fluids while taking Matium SR 450 Tablet to avoid dehydration.

You are not recommended to stop taking Matium SR 450 Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Matium SR 450 Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Matium SR 450 Tablet, please consult your doctor so that the dose may be gradually reduced.

You are not recommended to take Matium SR 450 Tablet with fluoxetine or other antidepressants such as paroxetine and sertraline as co-administration of these medicines may increase the risk of a rare and serious condition known as serotonin syndrome. If you experience blurred vision, increased heart rate, hallucination, fits, confusion, muscle stiffness or spasm, vomiting, nausea, diarrhoea, excessive sweating, stomach cramps, fever, shaking, or shivering, please consult a doctor immediately. However, before using Matium SR 450 Tablet with any other medicines, you are advised to contact your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Matium SR 450 Tablet as it may increase the risk of side effects such as drowsiness, dizziness or difficulty in concentrating.

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Pregnancy

Unsafe

Matium SR 450 Tablet is a Category D pregnancy drug and is not recommended for use during pregnancy as it may cause harm to the unborn baby.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Matium SR 450 Tablet as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Unsafe

Matium SR 450 Tablet may cause dizziness, drowsiness or other severe adverse effects. Therefore, avoid driving if you feel drowsy or dizzy after taking Matium SR 450 Tablet.

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Liver

Safe if prescribed

Matium SR 450 Tablet is safe to use in patients with liver diseases/conditions if prescribed by a doctor.

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Kidney

Caution

Take Matium SR 450 Tablet with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required. Matium SR 450 Tablet is not recommended for patients with severe kidney problems.

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Children

Caution

Matium SR 450 Tablet is generally not recommended for children below 12 years. However, Matium SR 450 Tablet may be used in children above 7 years for treating bipolar disorder only if prescribed by a doctor.

About Matium SR 450 Tablet

Matium SR 450 Tablet belongs to a psychological class of drugs called 'anti-manic agents' or 'mood stabilizers' primarily used to prevent and treat mood disorders like mania and bipolar disorder. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Bipolar disorder is a mental condition associated with extreme mood swings ranging from the hyper stage of mania to low mood depression.

Matium SR 450 Tablet contains Lithium carbonate that helps to treat mental disorders by increasing the activity of chemical messengers in the brain; thereby, suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood.

Take Matium SR 450 Tablet as prescribed. Your doctor will advise you on how often you need to take Matium SR 450 Tablet based on your medical condition. Some people may experience loss of appetite, dizziness, dry mouth, taste change, diarrhoea, blurred vision, slurred speech, shaky movements, increased thirst, and urination. Most of these side effects of Matium SR 450 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Matium SR 450 Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Matium SR 450 Tablet. Regular blood tests are recommended while taking Matium SR 450 Tablet to monitor the levels of lithium in blood. If you have fits, kidney or heart problems, thyroid, persistent headache, vision problems, and if you are planning or had weight loss surgery, please inform your doctor before taking Matium SR 450 Tablet.

Uses of Matium SR 450 Tablet

Bipolar disorder, Mania

Medicinal Benefits Mweb

Medicinal Benefits

Matium SR 450 Tablet is a mood stabilizer that is used to prevent and treat mood disorders such as mania and bipolar disorder. Matium SR 450 Tablet contains Lithium carbonate that helps to treat mental disorders by increasing the activity of chemical messengers in the brain; thereby, suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood. Thus, Matium SR 450 Tablet relaxes nerves and calms the mood, which helps in having a better social life and enables to do daily activities comfortably.

Directions for Use

Take Matium SR 450 Tablet with food for better absorption or take it as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Side Effects of Matium SR 450 Tablet

  • Loss of appetite
  • Dizziness
  • Dry mouth
  • Taste change
  • Diarrhoea
  • Blurred vision
  • Slurred speech
  • Shaky movements
  • Increased thirst and urination

Drug Warnings

Regular blood tests are recommended while taking Matium SR 450 Tablet to check lithium levels in the blood. If you are pregnant or breastfeeding, please inform your doctor before taking Matium SR 450 Tablet. If you have hypothyroidism (underactive thyroid gland), please inform your doctor before taking Matium SR 450 Tablet as it may cause low thyroid levels. If you notice decreased amount of urine, dark, reddish urine, muscle pain or weakness, inform your doctor immediately as it may be due to a serious condition called rhabdomyolysis (muscle tissue breakdown) which may lead to kidney problems.

Drug-Drug Interactions

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LithiumCidofovir
Critical
LithiumCisapride
Critical

Drug-Drug Interactions

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LithiumCidofovir
Critical
How does the drug interact with Matium SR 450 Tablet:
Cidofovir can cause higher levels of Matium SR 450 Tablet carbonate in the blood which increases risk of kidney problems.

How to manage the interaction:
Taking Matium SR 450 Tablet with Cidofovir is not recommended, but can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
LithiumCisapride
Critical
How does the drug interact with Matium SR 450 Tablet:
Taking Cisapride with Matium SR 450 Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Matium SR 450 Tablet with Cisapride is not recommended as it can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
LithiumGatifloxacin
Severe
How does the drug interact with Matium SR 450 Tablet:
Taking Gatifloxacin with Matium SR 450 Tablet can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Gatifloxacin with Matium SR 450 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or unusual memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LithiumLisinopril
Severe
How does the drug interact with Matium SR 450 Tablet:
Taking Matium SR 450 Tablet with lisinopril may significantly increase the blood levels of Matium SR 450 Tablet.

How to manage the interaction:
Although taking Lisinopril and Matium SR 450 Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience drowsiness, dizziness, confusion, loose stools, vomiting, muscle weakness, muscle incoordination, shaking, blurred vision, ringing in the ear, excessive thirst, and/or increased urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LithiumEscitalopram
Severe
How does the drug interact with Matium SR 450 Tablet:
Taking Matium SR 450 Tablet together with Escitalopram can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Escitalopram with Matium SR 450 Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
LithiumSertraline
Severe
How does the drug interact with Matium SR 450 Tablet:
Taking Matium SR 450 Tablet with Sertraline can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is an interaction between Sertraline and Matium SR 450 Tablet, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
LithiumFlurbiprofen
Severe
How does the drug interact with Matium SR 450 Tablet:
Co-administration of Flurbiprofen with Matium SR 450 Tablet may significantly increase the blood levels of Matium SR 450 Tablet.

How to manage the interaction:
There may be a possibility of interaction between Flurbiprofen and Matium SR 450 Tablet, but it can be taken if prescribed by a doctor. However, if you experience drowsiness, dizziness, confusion, loose stools, vomiting, muscle weakness, muscle incoordination, shaking of hands and legs, blurred vision, ringing in the ear, excessive thirst and increased urination contact your doctor immediately. Do not stop using any medications without a doctor's advice.
LithiumSpironolactone
Severe
How does the drug interact with Matium SR 450 Tablet:
Taking Matium SR 450 Tablet and spironolactone may increase blood levels of Matium SR 450 Tablet.

How to manage the interaction:
Although taking spironolactone and Matium SR 450 Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as loose stools, vomiting, drowsiness, shaking, thirst, lack of coordination, or muscle weakness. Do not stop using any medications without consulting doctor.
LithiumIvabradine
Severe
How does the drug interact with Matium SR 450 Tablet:
Coadministration of Ivabradine with Matium SR 450 Tablet can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Ivabradine with Matium SR 450 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or unusual memory loss. Do not discontinue any medications without consulting a doctor.
LithiumPerindopril
Severe
How does the drug interact with Matium SR 450 Tablet:
Perindopril when taken together with Matium SR 450 Tablet may significantly increase the blood levels of Matium SR 450 Tablet.

How to manage the interaction:
Although there is drug interaction between perindopril and Matium SR 450 Tablet, but can be taken together if advised by a doctor. if experience dizziness, confusion, diarrhea, vomiting, muscle weakness, tremor (shaking of hand & legs) blurred vision, ringing in the ear, excessive thirst, and/or increased urination consult a doctor immediately. Do not discontinue medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • RAMIPRIL
  • LISINOPRIL
  • METHYLDOPA
  • AMLODIPINE
  • DILTIAZEM
  • IBUPROFEN
  • DICLOFENAC
  • CELECOXIB
  • INDOMETHACIN
  • THEOPHYLLINE
  • OLANZAPINE
  • HALOPERIDOL
  • CLOZAPINE
  • SERTINDOLE
  • PHENYTOIN
  • CLONAZEPAM
  • CARBAMAZEPINE
  • QUINIDINE
  • AMIODARONE
  • PROPAFENONE
  • RANOLAZINE
  • PROCAINAMIDE
  • DISOPYRAMIDE
  • HYDROQUINIDINE
  • IBUTILIDE
  • SOTALOL
  • DOFETILIDE
  • PAROXETINE
  • AMITRIPTYLINE
  • FLUOXETINE
  • TRIMETHOPRIM
  • SPECTINOMYCIN
  • METRONIDAZOLE
  • TETRACYCLINE

Habit Forming

No

Special Advise

  • Regular blood tests are advised every week while taking Matium SR 450 Tablet to monitor the levels of lithium in blood. When lithium levels are constant, blood tests may be done every 3 months.
  • Drink a constant amount of water daily and maintain a constant sodium intake as any major changes in these two may alter the levels of lithium in blood.

Diet & Lifestyle Advise

  • Maintain a constant sodium diet as it may affect lithium levels in the blood and cause adverse effects.
  • Limit the intake of caffeine as it may reduce the effectiveness of Matium SR 450 Tablet.
  • Do regular exercise and maintain a stable weight as Matium SR 450 Tablet may cause weight gain.
  • Drink plenty of water to avoid dehydration and try to drink the same amount of water every day as any major changes in quantity may affect lithium levels.
  • Avoid consumption of alcohol as it may increase drowsiness.

Matium SR 450 Tablet Substitute

Substitutes safety advice
  • Lerithium CR 450 Tablet 10's

    by Others

    11.00per tablet
  • LITHONEX XL 450MG TABLET

    by Others

    11.70per tablet
  • Lithic SR 450 mg Tablet 10's

    by Others

    5.40per tablet
  • Lith-450 PR Tablet 10's

    by Others

    6.30per tablet
  • Lithocus 450 CR Tablet 10's

    by Others

    10.43per tablet
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