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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

AZACITIDINE-300MG

Manufacturer/Marketer :

Adley Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

CHEMOTHERAPY

Country of origin

India

Manufacturer/Marketer address

2/236, KAMBRATH THAZAM, PULLALUR, KURUVATTOOR PO, NA KOZHIKODE Kozhikode Kerala 673012
Other Info - MDS0004

FAQs

MDS-O 300 mg Tablet works by helping bone marrow in the production of normal blood cells and killing abnormal cells in the bone marrow.

MDS-O 300 mg Tablet may affect fertility in men and women. Consult the doctor if you have any concerns.

The doctor will prescribe anti-nausea medicine to help prevent nausea and vomiting during treatment with MDS-O 300 mg Tablet . Take the anti-nausea medicine 30 minutes before each dose of MDS-O 300 mg Tablet or as the doctor advises.

If you vomit after taking a dose MDS-O 300 mg Tablet , avoid taking another dose on the same day. Take the next dose at the regular time the next day. Talk to the doctor if you have any concerns.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Consult your doctor

It is not known if alcohol affects MDS-O 300 mg Tablet . Please consult your doctor.

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Pregnancy

Unsafe

MDS-O 300 mg Tablet can harm the unborn baby. Avoid becoming pregnant during treatment with MDS-O 300 mg Tablet . Consult the doctor immediately if you become pregnant during treatment with MDS-O 300 mg Tablet .

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Breast Feeding

Unsafe

Avoid breastfeeding during treatment with MDS-O 300 mg Tablet and for one week after the last dose.

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Driving

Consult your doctor

It is unknown if MDS-O 300 mg Tablet affects your ability to drive. Drive only if you are alert.

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Liver

Caution

If you have a history of liver disease, inform your doctor before taking MDS-O 300 mg Tablet .

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Kidney

Caution

If you have a history of kidney disease, inform your doctor before taking MDS-O 300 mg Tablet .

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Children

Unsafe

MDS-O 300 mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established.

About MDS-O 300 mg Tablet

MDS-O 300 mg Tablet belongs to the group of anti-cancer medicines called demethylation agents indicated for continued treatment of acute myeloid leukaemia in adults who improved after chemotherapy but could not complete intensive curative therapy. Acute myeloid leukaemia is a type of cancer that forms in the blood-forming cells of the bone marrow.

MDS-O 300 mg Tablet contains Azacitidine, which works by interfering with the growth of cancer cells, which are eventually destroyed by the body. It helps the bone marrow in the production of normal blood cells and kills abnormal cells in the bone marrow.
 
In some cases, MDS-O 300 mg Tablet may cause side effects such as nausea, vomiting, diarrhoea, constipation, fatigue and abdominal pain. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
 
Do not use MDS-O 300 mg Tablet if you are pregnant or breastfeeding. Consult a doctor immediately if you become pregnant during treatment with MDS-O 300 mg Tablet . This medicine is not recommended for children as safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of MDS-O 300 mg Tablet

Acute myeloid leukaemia

Medicinal Benefits Mweb

Medicinal Benefits

MDS-O 300 mg Tablet belongs to the group of anti-cancer medicines called demethylation agents indicated for continued treatment of adult patients with acute myeloid leukaemia who achieved first complete remission (all signs and symptoms of cancer have disappeared) or complete remission with incomplete blood count recovery following intensive induction chemotherapy and are not able to complete intensive curative therapy. MDS-O 300 mg Tablet contains Azacitidine, a nucleoside metabolic inhibitor which works by interfering with the growth of cancer cells, which are eventually destroyed by the body. It helps the bone marrow in the production of normal blood cells and kills abnormal cells in the bone marrow.

Directions for Use

Take MDS-O 300 mg Tablet with or without food. Swallow the medicine as a whole with water; do not crush or chew it.

Side Effects of MDS-O 300 mg Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Dizziness
  • Fatigue
  • Abdominal pain
  • Decreased appetite
  • Arthralgia (joint pain)

Drug Warnings

Do not take MDS-O 300 mg Tablet if you are allergic to any of its components or if you are breastfeeding. Inform the doctor if you have liver or kidney problems. Seek medical attention if you experience symptoms of neutropenia/low white blood cells (fever or chills, feeling very tired or weak, body aches, and unusual headache) or thrombocytopenia/low platelet count (unusual bleeding or bruising). Consult the doctor if you are pregnant, plan to become pregnant, or if you plan to father a child.

Drug-Drug Interactions

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AzacitidineYellow fever vaccine
Critical

Drug-Drug Interactions

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AzacitidineYellow fever vaccine
Critical
How does the drug interact with MDS-O 300 mg Tablet:
Taking Yellow fever vaccine with MDS-O 300 mg Tablet can increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between MDS-O 300 mg Tablet and the Yellow fever vaccine, you can take these medicines together if prescribed by a doctor. If you notice any signs of infection, it's important to contact a doctor right away. Do not stop using any medications without consulting a doctor.
How does the drug interact with MDS-O 300 mg Tablet:
When Etanercept is used with MDS-O 300 mg Tablet, the likelihood or severity of infection may increase.

How to manage the interaction:
There may be a possibility of interaction between Etanercept and MDS-O 300 mg Tablet, but it can be taken if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with MDS-O 300 mg Tablet:
Coadministration of Filgrastim with MDS-O 300 mg Tablet can reduce the effects of Filgrastim.

How to manage the interaction:
Although there is an interaction between filgrastim and MDS-O 300 mg Tablet, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AzacitidineCertolizumab
Severe
How does the drug interact with MDS-O 300 mg Tablet:
Taking MDS-O 300 mg Tablet with Certolizumab may raise the risk of severe infections.

How to manage the interaction:
Co-administration of MDS-O 300 mg Tablet with Certolizumab can result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of these symptom's fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with MDS-O 300 mg Tablet:
Taking MDS-O 300 mg Tablet with Teriflunomide can increase the risk of developing serious infections.

How to manage the interaction:
Although taking MDS-O 300 mg Tablet and Teriflunomide together can cause an interaction, it can be taken if a doctor has suggested it. However, consult a doctor immediately if you have a fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not stop using any medications without talking to a doctor.
How does the drug interact with MDS-O 300 mg Tablet:
Taking MDS-O 300 mg Tablet with Natalizumab can raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between MDS-O 300 mg Tablet and Natalizumab, but it can be taken if prescribed by a doctor. However, if you have any of these symptoms- fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, blood in phlegm(a thick secretion in the airway during disease and inflammation), losing weight, or pain while peeing, progressive weakness on one side of the body, clumsiness of limbs, disturbance of vision, confusion, or changes in thinking, memory and personality, make sure to contact a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with MDS-O 300 mg Tablet:
Taking thalidomide together with MDS-O 300 mg Tablet may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and MDS-O 300 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
How does the drug interact with MDS-O 300 mg Tablet:
Taking baricitinib and MDS-O 300 mg Tablet can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with MDS-O 300 mg Tablet if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with MDS-O 300 mg Tablet:
Taking Infliximab with MDS-O 300 mg Tablet can increase the risk or severity of developing infection.

How to manage the interaction:
Although taking MDS-O 300 mg Tablet and Infliximab together can cause an interaction, it can be taken if a doctor has suggested it. If you experience symptoms like fever, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, and pain or burning during urination, it is recommended to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AzacitidineGolimumab
Severe
How does the drug interact with MDS-O 300 mg Tablet:
Taking MDS-O 300 mg Tablet with Golimumab can raise the risk of severe infections.

How to manage the interaction:
Co-administration of MDS-O 300 mg Tablet with Golimumab can result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of these symptom's fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Habit Forming

No

Special Advise

  • If you are a female, you should take a pregnancy test prior to the start of the treatment. Use reliable contraception to prevent pregnancy during treatment and for 6 months after the last dose.
  • Male patients with partners of reproductive potential should use effective contraception during treatment and for 3 months after stopping the treatment.
  • If the powder from the medicine comes in contact with your skin, wash the area well with soap and water immediately.
  • If the powder from the medicine comes in contact with mucous membranes (eyes or mouth), flush the area with water immediately.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly as it helps maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat fibre-rich foods, vegetables and fruits.

MDS-O 300 mg Tablet Substitute

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