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  1. Home
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  3. Mesacol Enema 60 ml

Mesacol Enema 60 ml, Pack of 1 Enema
Mesacol Enema 60 ml, Pack of 1 Enema
Mesacol Enema 60 ml, Pack of 1 Enema
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Know More

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Whats That

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Synonym :

MESALAZINE

Composition :

MESALAMINE-4GM

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

RECTAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - MES0002

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:47 AM IST

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Alcohol

Caution

The interaction of alcohol with Mesacol Enema is unknown. However, avoid consuming alcohol while on treatment with this medicine.

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Pregnancy

Consult your doctor

Mesacol Enema should not be used in pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Mesacol Enema.

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Breast Feeding

Consult your doctor

Mesacol Enema should not be used while breastfeeding unless necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Mesacol Enema.

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Driving

Not applicable

Mesacol Enema usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Inform your doctor before receiving Mesacol Enema if you have a history of liver diseases/conditions. It should be used cautiously in patients with mild to moderately impaired liver function. It is recommended not to be used in populations with severe liver impairment.

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Kidney

Caution

Inform your doctor before receiving Mesacol Enema if you have a history of kidney diseases/conditions. It should be used cautiously in patients with mild to moderately impaired kidney function. It is recommended not to be used in populations with severe kidney impairment.

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Children

Caution

Mesacol Enema is intended for adults. Not recommended for children.

Reference

  1. https://ciplamed-library.com/content/mesalo-foam
  2. https://www.nhs.uk/medicines/mesalazine/
  3. https://www.medicines.org.uk/emc/files/pil.914.pdf

About Mesacol Enema

Mesacol Enema belongs to a class of anti-inflammatory drugs used to treat ulcerative colitis and ulcerative proctitis. Ulcerative colitis is a chronic inflammatory bowel disease that causes inflammation of the large intestine lining (colon). It produces ulcers on the colon's lining, which may cause bleeding and discharge of pus and mucus. Ulcerative proctitis is a condition in which ulcerative colitis solely affects the rear channel (rectum).

Mesacol Enema contains Mesalamine, which works by preventing the synthesis of chemical messengers such as prostaglandins in the intestines that produce inflammation (swelling). This lowers ulceration, bleeding, and stomach pain while preventing future illness flare-ups.

Use Mesacol Enema as directed by your physician. Sometimes, you may experience diarrhoea, stomach pain, headache or nausea. Most of these side effects of Mesacol Enema do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Before taking the Mesacol Enema, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you have severe kidney or liver failure or blood abnormalities like porphyria. Mesacol Enema should not be used in pregnant and breastfeeding mothers unless necessary. So, inform your doctor if you are pregnant or breastfeeding. Your doctor will weigh the benefits and potential risks before prescribing Mesacol Enema.

Uses of Mesacol Enema

Ulcerative colitis, Ulcerative proctitis

Medicinal Benefits Mweb

Medicinal Benefits

Mesacol Enema contains Mesalamine, an anti-inflammatory drug used to treat ulcerative colitis and ulcerative proctitis. It can also help treat other inflammatory bowel disease types, such as Crohn’s disease. It works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby helping reduce inflammation (redness and swelling) in the intestines and providing relief from symptoms such as stomach pain or bleeding. Also, Mesacol Enema may prevent further episodes of ulcerative colitis. It is especially useful when ulcerative colitis symptoms affect the rectum.

Directions for Use

Suppository: Empty your bowels if required. Wash your hands thoroughly before and after use. Lie down on your left side and raise your right knee to the chest. Remove the wrapper and insert the pointed end of the suppository into the rectum. If necessary, grease the suppository tip with petroleum jelly.Enema: Use it as advised by the doctor. Shake the bottle well and remove the protective shield from the tip. Lie down on your left side, raise your right knee to the chest, or kneel and lean forward so that the head and chest are resting comfortably. Insert the enema bottle into the rectum with the tip pointing towards the navel. Squeeze the bottle gently until it is empty. Remove the bottle from the rectum and wash your hands thoroughly.Rectal foam: It should be used as directed by your doctor. It is exclusively intended for rectal usage. Before using, empty your bowels (if necessary) and wash your hands. Shake the bottle vigorously for at least 30 seconds. Remove the applicator's protective cap and hold the bottle by its top end. Lie on your left side, your left leg extended and your right leg bent. Insert the applicator (lubricant-coated) for easier entry into the rectum. Squeeze the bottle gently while holding it directed towards your navel. When the bottle is empty, remove the applicator from the rectum. Allow the drug to spread throughout the lower section of the large intestine for at least 30 minutes by remaining in this posture. Wash your hands (after usage) and wait till the next morning to empty your bowels. Your doctor will choose the appropriate amount and duration for you based on your age, body weight, and medical state.

Side Effects of Mesacol Enema

  • Feeling sick (Nausea)
  • Being sick (Vomiting)
  • Diarrhoea
  • Stomach pain, indigestion
  • Headaches
  • Muscle aches

Drug Warnings

Before taking the Mesacol Enema, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Do not use Mesacol Enema if you are pregnant, planning to become pregnant, or breastfeeding without first consulting the doctor. Mesacol Enema is recommended not to be used in populations with severe renal or hepatic impairment, so inform your doctor if you have severe renal or hepatic impairment. Use Mesacol Enema in dose and duration as advised by a doctor only. Do not swallow Mesacol Enema. In case of accidental swallowing, drink plenty of water and consult a doctor immediately.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • AZATHIOPRINE
  • WARFARIN
  • LACTULOSE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a low-fat diet and eat foods rich in vitamin C, such as bell peppers, spinach, parsley and berries, which help heal faster.
  • Opt for food and drinks high in Omega 3 fatty acids to relieve pain, swelling, and inflammation. Omega 3 rich acid-enriched foods include flaxseeds, walnut, soybean oil, salmon, and tuna if you prefer non-veg.
  • Eat more fibre-rich foods such as fruits and vegetables.
  • Eat smaller meals all day.
  • Drink small amounts of water throughout the day.
  • If you are intolerant to lactose, lower your intake of milk.
  • Avoid foods high in sugar, fat, and processed foods, as these, may cause inflammation.
  • Try to avoid alcohol as it can affect your stomach and intestine and also limits the absorption of the important nutrients required by your body.

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