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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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in last 7 days

Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

MISCELLANEOUS

Country of origin

India

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - MET0067

FAQs

Methergin Tablet works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

Methergin Tablet is not recommended for use in people with high blood pressure. Consult your doctor if you have hypertension.

Methergin Tablet may cause nausea or vomiting as a side effect. It is not necessary for everyone taking Methergin Tablet to experience this side effect. However, if the condition persists or worsens, consult your doctor.

Methergin Tablet may be indicated in the management of uterine atony. Uterine atony refers to a weak and soft uterus after childbirth.

Disclaimer

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Alcohol

Caution

It is not known if alcohol affects Methergin Tablet . Please consult your doctor.

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Pregnancy

Unsafe

Methergin Tablet is not recommended for use during pregnancy.

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Breast Feeding

Caution

Methergin Tablet passes into breastmilk. Avoid breastfeeding during treatment with Methergin Tablet and for 12 hours after the last dose. Please consult your doctor if you have any concerns.

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Driving

Caution

It is not known if Methergin Tablet affects your ability to drive.

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Liver

Caution

Caution should be exercised while using Methergin Tablet in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

Caution should be exercised while using Methergin Tablet in patients with kidney impairment. Please consult your doctor if you have kidney problems or any concerns regarding this.

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Children

Unsafe

Methergin Tablet is not recommended for children as safety and effectiveness have not been established.

About Methergin Tablet

Methergin Tablet belongs to the class of medication called semi-synthetic ergot alkaloids used to prevent and control postpartum haemorrhage. It is used after delivery for the routine management of uterine atony, subinvolution of the uterus, and haemorrhage.

Methergin Tablet contains Methylergometrine which works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

Take Methergin Tablet exactly as prescribed by the doctor. In some cases, Methergin Tablet may cause high blood pressure associated with seizures and/or headache, nausea, and vomiting. If the side effects persist or worsen, consult your doctor.

Do not take Methergin Tablet if you are pregnant. Consult your doctor if you are breastfeeding. Methergin Tablet is not recommended for children as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of Methergin Tablet

Postpartum haemorrhage

Medicinal Benefits Mweb

Medicinal Benefits

Methergin Tablet is indicated in the prevention and control of postpartum haemorrhage. It is used following delivery of the placenta for the routine management of uterine atony (soft and weak uterus after childbirth), subinvolution of the uterus, and haemorrhage. Methergin Tablet contains Methylergometrine, a semi-synthetic ergot alkaloid which works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

Directions for Use

Swallow Methergin Tablet as a whole with water; do not crush, break or chew it.

Side Effects of Methergin Tablet

  • Hypertension (high blood pressure) associated with seizures and/or headache
  • Nausea
  • Vomiting

Drug Warnings

Do not take Methergin Tablet if you are allergic to any of its components, if you have high blood pressure, toxaemia (a complication of pregnancy characterised by high blood pressure), or if you are pregnant. Inform your doctor if you have coronary artery disease, sepsis, vascular disease, or liver or kidney impairment. Consult your doctor if you are breastfeeding. The safety and effectiveness of Methergin Tablet in children have not been established. Let your doctor know if you are taking prescription/non-prescription medicines, including herbal products and supplements.

Drug-Drug Interactions

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MethylergometrineClarithromycin
Critical
MethylergometrineKetoconazole
Critical

Drug-Drug Interactions

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MethylergometrineClarithromycin
Critical
How does the drug interact with Methergin Tablet:
When Methergin Tablet is taken with Clarithromycin, the amount of Methergin Tablet in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Clarithromycin with Methergin Tablet is generally avoided as it can lead to an interaction, it can be taken only when advised by a doctor. Do not stop using any medications without a doctor's advice.
MethylergometrineKetoconazole
Critical
How does the drug interact with Methergin Tablet:
Using Ketoconazole with Methergin Tablet can increase the concentration of Methergin Tablet, which may lead to side effects.

How to manage the interaction:
Taking Ketoconazole with Methergin Tablet is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineRitonavir
Critical
How does the drug interact with Methergin Tablet:
Taking Methergin Tablet with Ritonavir can significantly increase the blood levels and effects of Methergin Tablet.

How to manage the interaction:
Taking Methergin Tablet with Ritonavir is not recommended, but can be taken together if prescribed by a doctor. In case you experience any side effects like severe abdominal discomfort, nausea, vomiting, tingling or numbness, weakness or pain in the muscles, pale skin, blue or purple discoloration on fingers or toes, tightness or pain in the chest, irregular heartbeat, intense headache, breathing difficulties, confusion, or slurred speech, consult a doctor. Do not discontinue any medications without consulting a doctor.
MethylergometrineItraconazole
Critical
How does the drug interact with Methergin Tablet:
Co-administration of Methergin Tablet and Itraconazole may increase the blood levels of Methergin Tablet.

How to manage the interaction:
Methergin Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Do not discontinue any medications without first consulting your doctor.
MethylergometrineGlyceryl trinitrate
Critical
How does the drug interact with Methergin Tablet:
Coadministration of Methergin Tablet with Glyceryl trinitrate can increase the levels and side effects of Methergin Tablet.

How to manage the interaction:
Taking Methergin Tablet with Glyceryl trinitrate is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, headache, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor. Do not discontinue any medications without first consulting your doctor.
MethylergometrineSumatriptan
Critical
How does the drug interact with Methergin Tablet:
Coadministration of Sumatriptan with Methergin Tablet can reduce the blood flow and increase the risk of high blood pressure or heart-related problems.

How to manage the interaction:
Taking Sumatriptan with Methergin Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
MethylergometrineVoriconazole
Critical
How does the drug interact with Methergin Tablet:
Coadministration of Methergin Tablet with Voriconazole may increase the blood level of Methergin Tablet.

How to manage the interaction:
Although Methergin Tablet with Voriconazole can cause an interaction, they can be taken if prescribed by a doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineEphedrine
Severe
How does the drug interact with Methergin Tablet:
Taking Ephedrine with Methergin Tablet may lead to an increase in the risk of high blood pressure.

How to manage the interaction:
Although taking Ephedrine with Methergin Tablet may lead to an interaction, it can be taken if prescribed by the doctor. It is advised to maintain your blood pressure. Do not discontinue any medications without a doctor's advice.
MethylergometrinePhenylephrine
Severe
How does the drug interact with Methergin Tablet:
Taking Phenylephrine with Methergin Tablet can led to side effects like increased blood pressure.

How to manage the interaction:
Taking Phenylephrine with Methergin Tablet can lead to an interaction but can be taken if prescribed by the doctor. It is advised to monitor your blood pressure regularly. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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METHYLERGOMETRINE-0.125MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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METHYLERGOMETRINE-0.125MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of Methergin Tablet with Grapefruit and Grapefruit may lead to an increase in the effectiveness of Methergin Tablet. Avoid or limit grapefruit and grapefruit juice consumption with Methergin Tablet. This can increase the risk or severity of side effects.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DIHYDROERGOTAMINE
  • ERGOTAMINE
  • ERYTHROMYCIN
  • TROLEANDOMYCIN
  • CLARITHROMYCIN
  • RITONAVIR
  • INDINAVIR
  • NELFINAVIR
  • DELAVIRDINE
  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE

Habit Forming

No

Special Advise

 

Diet & Lifestyle Advise

  • Include high-fibre foods such as fruits and whole grains.
  • Drink plenty of fluids such as water, fruit juices, and milk.
  • Limit processed/packaged foods, high salt/sugary foods and saturated fats.
  • Get plenty of rest.
  • Eat healthy meals and exercise appropriately.

Methergin Tablet Substitute

Substitutes safety advice
  • Ergostat Tablet 10's

    by AYUR

    9.00per tablet
  • Wergomet 0.125mg Tablet

    by Others

    4.86per tablet
  • UTERGIN 0.125MG TABLET

    by Others

    78.12per tablet
  • Utergin Tablet 10's

    by Others

    9.00per tablet
  • Nugine 0.125mg Tablet

    by Others

    6.30per tablet
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