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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

METHOTREXATE-50MG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Apr-24

Therapeutic Class

ANTIMETABOLITES

Country of origin

India
Other Info - MET0296

Author Details

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FAQs

Methocel 50 mg Injection 1's acts as an immunosuppressant, which helps in reducing inflammation and prevents joint stiffness, thereby providing relief from rheumatoid arthritis.
Methocel 50 mg Injection 1's works by suppressing the overactive immune system that is responsible for causing psoriasis. Methocel 50 mg Injection 1's interferes with the synthesis of genetic material (DNA) and the growth of cells that multiply faster than usual, thereby helping in treating psoriasis.
Methocel 50 mg Injection 1's may affect fertility in men and women. Consult your doctor if you have any concerns regarding this.
Methocel 50 mg Injection 1's causes leukopenia (decreased number of white blood cells) and hence may make you more susceptible to infections. Consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.
Methocel 50 mg Injection 1's may make your skin sensitive to sunlight. Therefore, avoid prolonged or unnecessary exposure to sunlight or ultraviolet light such as tanning beds and sunlamps. Wear protective clothing, sunglasses, and sunscreen while going out.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Methocel 50 mg Injection 1's.

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Pregnancy

Unsafe

Methocel 50 mg Injection 1's may cause serious birth defects. It is not recommended to take Methocel 50 mg Injection 1's while you are pregnant.

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Breast Feeding

Unsafe

Methocel 50 mg Injection 1's passes into breast milk. Avoid breastfeeding whilst on treatment with Methocel 50 mg Injection 1's and for at least 1 week after the last dose.

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Driving

Caution

Methocel 50 mg Injection 1's may cause dizziness and tiredness; do not drive or operate heavy machinery until you know how Methocel 50 mg Injection 1's affects you.

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Liver

Caution

Please consult your doctor if you have liver impairment before taking Methocel 50 mg Injection 1's.

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Kidney

Caution

Please consult your doctor if you have kidney impairment before taking Methocel 50 mg Injection 1's.

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Children

Caution

The efficacy and safety of Methocel 50 mg Injection 1's in children have been established in polyarticular-course juvenile rheumatoid arthritis and cancer chemotherapy. Please consult your doctor if you have any concerns regarding the usage of Methocel 50 mg Injection 1's in children.

About Methocel 50 mg Injection 1's

Methocel 50 mg Injection 1's belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat active rheumatoid arthritis, including polyarticular juvenile rheumatoid arthritis and severe psoriasis. Methocel 50 mg Injection 1's is also used to treat cancer such as breast cancer, cervical cancer, bladder cancer, ovarian cancer, testicular cancer, lung cancer, head and neck cancer, mycosis fungoides (type of blood cancer), bone cancer, and advanced stage non-Hodgkin's lymphomas (cancer that starts in the lymphatic system).

Methocel 50 mg Injection 1's contains 'Methotrexate' that works by interrupting the processes of the immune system that cause inflammation in the joint tissues. It reduces pain and inflammation and delays joint damage and disease progression over time. Besides this, Methocel 50 mg Injection 1's prevents and stops the growth of cancer cells, thereby helps treat cancer. Methocel 50 mg Injection 1's treats psoriasis by suppressing the overactive immune system that is responsible for causing psoriasis.

Methocel 50 mg Injection 1's will be administered by a qualified healthcare professional; do not self-administer. In some cases, Methocel 50 mg Injection 1's may cause side-effects such as nausea, vomiting, diarrhoea, unusual fatigue, dizziness, headache, loss of appetite, lowered resistance to infections, tingling sensation, leukopenia (decreased number of white blood cells), and soreness of mouth and lips. You are advised to talk to your doctor if you experience any of the side effects persistently.

Do not take Methocel 50 mg Injection 1's if you are pregnant or breastfeeding. Methocel 50 mg Injection 1's may cause dizziness and fatigue, so avoid driving or operating machinery. Avoid consuming alcohol whilst on treatment with Methocel 50 mg Injection 1's. If you are due to undergo any surgery, including dental surgery, inform the doctor that you are receiving Methocel 50 mg Injection 1's. Do not have any vaccinations during treatment with Methocel 50 mg Injection 1's without consulting your doctor. Inform your doctor about your medications and health condition to rule out any unpleasant side effects.

Uses of Methocel 50 mg Injection 1's

Rheumatoid arthritis, Psoriasis, Cancer

Medicinal Benefits Mweb

Medicinal Benefits

Methocel 50 mg Injection 1's belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat active rheumatoid arthritis including polyarticular juvenile rheumatoid arthritis (arthritis in children) and severe psoriasis. Methocel 50 mg Injection 1's helps treat rheumatoid arthritis by interrupting the processes of the immune system that cause inflammation in the joint tissues. It reduces pain and inflammation and delays joint damage and disease progression over time. Methocel 50 mg Injection 1's treats psoriasis by suppressing the overactive immune system that is responsible for causing psoriasis. Methocel 50 mg Injection 1's is used to treat breast cancer, lung cancer, head and neck cancer, mycosis fungoides (type of blood cancer), and advanced stage non-Hodgkin's lymphomas (cancer that starts in the lymphatic system). Methocel 50 mg Injection 1's prevents and stops the growth of cancer cells by interfering with DNA production.

Directions for Use

Methocel 50 mg Injection 1's will be administered by a qualified healthcare professional; do not self-administer.

Side Effects of Methocel 50 mg Injection 1's

  • Nausea
  • Vomiting
  • Diarrhoea
  • Unusual fatigue
  • Dizziness
  • Headache
  • Loss of appetite
  • Elevated liver enzymes
  • Lowered resistance to infections
  • Tingling sensation
  • Leukopenia (decreased number of white blood cells)
  • Soreness of mouth and lips

Drug Warnings

Do not take Methocel 50 mg Injection 1's if you are allergic to any of its contents; if you are pregnant or breastfeeding. Inform your doctor if you have immunodeficiency conditions, bone marrow problems, low white blood cell count, low platelet count, serious anaemia, liver problems due to alcohol abuse, liver, lung or kidney problems, ulceration in the stomach or bowels, poor general condition, received any vaccinations or if are due to have any, diabetes, ascites (fluid in the stomach area), lung problems or fluid in the lungs. Methocel 50 mg Injection 1's may cause a serious, life-threatening reaction. If you experience symptoms such as rash, itching, hives, throat tightness, trouble swallowing, swelling of the face, throat, lips, or tongue; runny or stuffy nose, lightheadedness or dizziness, chest pain, difficulty breathing, wheezing, or feeling faint, consult your doctor immediately. Inform your doctor if you are undergoing radiation therapy; if you receive Methocel 50 mg Injection 1's while you are being treated with radiation therapy for cancer, it may cause damage to the skin, bones, or other parts of the body.

Drug-Drug Interactions

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MethotrexateEtretinate
Critical
MethotrexateAcitretin
Severe

Drug-Drug Interactions

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MethotrexateEtretinate
Critical
How does the drug interact with Methocel 50 mg Injection 1's:
Co-administration of Etretinate with Methocel 50 mg Injection 1's may increase the risk or severity of liver problems.

How to manage the interaction:
Taking Etretinate with Methocel 50 mg Injection 1's is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
MethotrexateAcitretin
Severe
How does the drug interact with Methocel 50 mg Injection 1's:
Co-administration of Acitretin with Methocel 50 mg Injection 1's may increase the risk or severity of liver problems.

How to manage the interaction:
Although there is a possible interaction between Acitretin with Methocel 50 mg Injection 1's, you can take these medicines together if only when prescribed by a doctor. Do not discontinue any medications without talking to a doctor.
MethotrexateAmpicillin
Severe
How does the drug interact with Methocel 50 mg Injection 1's:
Co-administration of Methocel 50 mg Injection 1's with Ampicillin can increase the levels and side effects of Methocel 50 mg Injection 1's.

How to manage the interaction:
Although there is a possible interaction between Methocel 50 mg Injection 1's and ampicillin, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as tiredness, dizziness, fainting, unusual bleeding or bruising, chills, fever, sore throat, body pains. Consult a doctor immediately. Do not stop using medications without a doctor's advice.
MethotrexateEtodolac
Severe
How does the drug interact with Methocel 50 mg Injection 1's:
Co-administration of Methocel 50 mg Injection 1's with etodolac can increase the level and effects of Methocel 50 mg Injection 1's. This can increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Methocel 50 mg Injection 1's and etodolac, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, pallor, dizziness or fainting, unusual bruising or bleeding, seizures, infection; as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
MethotrexatePiroxicam
Severe
How does the drug interact with Methocel 50 mg Injection 1's:
Coadministration of Methocel 50 mg Injection 1's with piroxicam can increase the levels and side effects.

How to manage the interaction:
Although there is a possible interaction between piroxicam and Methocel 50 mg Injection 1's, it can be taken if prescribed by a doctor. However, if you experience any symptoms such as mouth ulcers or sores, vomiting, fever, chills, body aches, sore throat, muscle weakness, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, breathing difficulty, dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, seizures(fits), Consult a doctor. Do not stop using any medications without consulting a doctor.
MethotrexateBaricitinib
Severe
How does the drug interact with Methocel 50 mg Injection 1's:
Co-administration of Baricitinib and Methocel 50 mg Injection 1's can increase the risk or severity of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Baricitinib and Methocel 50 mg Injection 1's, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, and pain or burning during urination. Consult a doctor. Do not stop using any medications without consulting a doctor.
MethotrexateTacrolimus
Severe
How does the drug interact with Methocel 50 mg Injection 1's:
Taking tacrolimus with Methocel 50 mg Injection 1's may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between tacrolimus and Methocel 50 mg Injection 1's, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, dizziness. Consult your doctor. Do not stop using any medications without consulting to a doctor.
MethotrexateMefenamic acid
Severe
How does the drug interact with Methocel 50 mg Injection 1's:
Coadministration of Mefenamic acid with Methocel 50 mg Injection 1's may increase the blood levels and side effects of Methocel 50 mg Injection 1's.

How to manage the interaction:
Although there is a possible interaction between mefenamic acid and Methocel 50 mg Injection 1's, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, breathing difficulty, a dry cough, dizziness or fainting, unusual bruising or bleeding, seizures(fits), mouth sores or ulcers, infection, as well as flu-like symptoms(fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
MethotrexateCladribine
Severe
How does the drug interact with Methocel 50 mg Injection 1's:
Co-administration of Methocel 50 mg Injection 1's with cladribine can increase the risk or severity of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between cladribine and Methocel 50 mg Injection 1's, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, and pain or burning during urination, Consult a doctor. Do not stop using any medications without consulting a doctor.
MethotrexateOxacillin
Severe
How does the drug interact with Methocel 50 mg Injection 1's:
Coadministration of Methocel 50 mg Injection 1's with oxacillin can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between oxacillin and Methocel 50 mg Injection 1's, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin and pain or burning during urination. Consult your doctor. Do not stop using any medications without first consulting to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CISPLATIN
  • MERCAPTOPURINE
  • AZATHIOPRINE
  • TETRACYCLINE
  • CHLORAMPHENICOL
  • SULFASALAZINE

Habit Forming

No

Special Advise

  • Women of child-bearing potential must use effective contraception whilst on treatment with Methocel 50 mg Injection 1's and for at least 6 months after the last dose.
  • If you are a male, you and your partner should use reliable contraception during treatment with Methocel 50 mg Injection 1's and for at least 3 months after the last dose.
  • Methocel 50 mg Injection 1's may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.
  • Your doctor may advise regular blood tests, kidney and liver tests to monitor your condition.

Diet & Lifestyle Advise

Arthritis:

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle exercises like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help reduce inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Psoriasis:

  • Include foods such as cherries, berries, leafy vegetables, salmon, sardines, and fish rich in omega-3 fatty acids.
  • Consume antioxidant-rich spices and herbs like cumin, ginger, sage and thyme.
  • Avoid processed foods, refined sugars, and fatty foods.
  • Limit intake of food that might trigger allergies, such as dairy products, soy, eggs, and nuts.
  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
  • Reducing stress and maintaining a good sleep cycle would be helpful.
  • Avoiding getting in contact with harsh soaps, detergents and rough fabrics.

Cancer:

  • Consume a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.

Methocel 50 mg Injection 1's Substitute

Substitutes safety advice
  • Biotrexate 15Mg Inj

    by AYUR

    84.60per tablet
  • Biotrexate 500 mg Injection 5 ml

    by Others

    203.58per tablet
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