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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

PYRIDOSTIGMINE-60MG

Manufacturer/Marketer :

First Horizon Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

MUSCLE STIMULANTS AND CHOLINESTERASE INHIBITORS

Country of origin

India

Manufacturer/Marketer address

A 102, VAIBHAV BLDG., JAI VAIBHAV C.H.S. JAMLI GALLI, BORIVALI (W), MUMBAI-400 092
Other Info - MET0419

Author Details

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FAQs

Methyzone Tablet works by stopping the excessive cholinesterase activity (an enzyme necessary for the breakdown of a neurotransmitter called acetylcholine) involved in communication between nerve impulses and muscle movements. Thereby, Methyzone Tablet helps in proper muscle functioning and prevents muscle weakness.

Methyzone Tablet is used as prophylaxis against the lethal effects of soman nerve agent poisoning especially by military. It is intended to be used in conjunction with atropine and pralidoxime therapy and protective garments and gas-mask.

Do not stop taking Methyzone Tablet on your own. To treat your condition effectually continue taking Methyzone Tablet for as long as your doctor has prescribed it. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Methyzone Tablet .

Caution is needed in patients with asthma, breathing difficulty, wheezing and chronic cough as Methyzone Tablet may worsen the condition. Please consult your doctor before taking Methyzone Tablet if you have asthma or any breathing problems.

Talk to your doctor before taking Methyzone Tablet if you have hypertension (high blood pressure) as it may cause insignificant changes such as elevated blood pressure.

Anticholinergic drugs are often used in the treatment of glaucoma. Methyzone Tablet is a cholinergic inhibitor, and its use in patients with glaucoma may cause additive effects which could lead to night vision problems. Please consult your doctor before taking Methyzone Tablet if you have glaucoma.

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Alcohol

Unsafe

Avoid consuming alcohol while taking Methyzone Tablet as it may cause increased dizziness.

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Pregnancy

Caution

Methyzone Tablet belongs to the pregnancy category C. Please consult your doctor before taking Methyzone Tablet if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Small amounts of Methyzone Tablet may pass into breastmilk. Please consult your doctor before taking Methyzone Tablet if you are breastfeeding.

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Driving

Unsafe

Methyzone Tablet may cause dizziness and vision problems. So, drive only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor before taking Methyzone Tablet if you have liver impairment/liver disease before taking Methyzone Tablet .

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Methyzone Tablet .

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Children

Unsafe

Not recommended for use in anyone less than 18 years of age

About Methyzone Tablet

Methyzone Tablet belongs to the group of medicines called cholinesterase inhibitors used to treat myasthenia gravis (muscle weakness). Besides this, Methyzone Tablet also streats paralytic ileus (a rare form of constipation), postoperative urinary retention, and prophylaxis to military exposuree to any nerve poisoning gas. Myasthenia gravis is a long term neuromuscular disease that leads to musculoskeletal weakness caused by excess activity of a cprotein.cholinesterase protein 

Methyzone Tablet contains ‘Pyridostigmine’ which works by stopping the excessive cholinesterase activity (an enzyme required for the breakdown of a neurotransmitter called acetylcholine) involved in communication between nerve impulses and muscle movements. Thereby, Methyzone Tablet helps in proper muscle functioning and prevents muscle weakness. 

Take Methyzone Tablet 30-60 minutes before food. Swallow Methyzone Tablet as a whole; do not crush or chew the tablet. You are advised to take Methyzone Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as stomach pain, nausea, vomiting, diarrhoea, sweating, cough with mucus, rash, muscle cramps, and blurred vision. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Inform your doctor before taking Methyzone Tablet if you have asthma, high blood pressure, glaucoma, breathing problems, coronary obstruction, stomach ulcer, epilepsy, Parkinson’s disease, or kidney problems. Consult your doctor before taking Methyzone Tablet if you are pregnant before taking Methyzone Tablet if you are pregnant or breastfeeding. Methyzone Tablet may cause dizziness and vision problems; so, drive or operate machinery only if you are alert. Avoid consuming alcohol while taking Methyzone Tablet as it may cause increased dizziness. Methyzone Tablet can be given to children if prescribed by the doctor; the dose depends upon the child’s age. Keep your doctor informed about your health condition and medicines you are taking to rule out unpleasant side-effects.

Uses of Methyzone Tablet

Myasthenia gravis (muscle weakness)

Medicinal Benefits Mweb

Medicinal Benefits

Methyzone Tablet belongs to the group of medicines called cholinesterase inhibitors used to treat myasthenia gravis (muscle weakness). Methyzone Tablet works by stopping the excessive activity of cholinesterase, thereby helps the muscles to work properly. Additionally, Methyzone Tablet is also used to treat paralytic ileus (a rare form of constipation), postoperative urinary retention, and prophylaxis to soman nerve agent poisoning. Methyzone Tablet affects the chemicals in the body which are involved in communication between nerve impulses and muscle movements. Thereby, Methyzone Tablet helps in treating myasthenia gravis.

Directions for Use

Take Methyzone Tablet 30-60 minutes before food. Swallow Methyzone Tablet as a whole; do not crush or chew the tablet. The dose and duration of Methyzone Tablet can vary depending upon your condition. Your doctor will decide the dose and frequency of the medicine you will take.

Side Effects of Methyzone Tablet

  • Stomach pain
  • Nausea
  • Vomiting
  • Diarrhoea
  • Increased salivation (drooling)
  • Sweating, cough with mucus
  • Rash
  • Muscle cramps
  • Blurred vision

Drug Warnings

Do not take Methyzone Tablet if you are allergic to any of its contents; if you are constipated or cannot urinate unless prescribed by the doctor. Inform your doctor before taking Methyzone Tablet if you have asthma, high blood pressure, glaucoma, breathing problems, coronary obstruction, stomach ulcer, epilepsy, Parkinson’s disease, kidney problems, vagotonia (overactive vagus nerves), overactive thyroid; if you have had surgery to remove thymus gland or if you due to have any surgery. Consult your doctor before taking Methyzone Tablet if you are pregnant before taking Methyzone Tablet if you are pregnant or breastfeeding. Methyzone Tablet may cause dizziness and vision problems; so, drive or operate machinery only if you are alert. Avoid consuming alcohol while taking Methyzone Tablet as it may cause increased dizziness. 

Drug-Drug Interactions

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MecobalaminChloramphenicol
Moderate
MecobalaminNeomycin
Moderate

Drug-Drug Interactions

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MecobalaminChloramphenicol
Moderate
How does the drug interact with Methyzone Tablet:
Coadministration of Methyzone Tablet with Chloramphenicol can impair absorption and increase the levels of Methyzone Tablet which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Methyzone Tablet with Chloramphenicol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of Vomiting, Diarrhoea, Nausea, Headache, or Loss of appetite, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
MecobalaminNeomycin
Moderate
How does the drug interact with Methyzone Tablet:
Coadministration of Methyzone Tablet with Neomycin can impair the absorption of Methyzone Tablet and increase its levels which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Methyzone Tablet with Neomycin together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of Vomiting, Diarrhoea, Nausea, Headache, or Loss of appetite you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ATROPINE
  • GLYCOPYRROLATE
  • PREDNISONE
  • SUCCINYLCHOLINE

Habit Forming

No

Special Advise

  • Methyzone Tablet might stop or increase the effects of skeletal muscle relaxants used in the surgery. Inform the doctor that you are taking Methyzone Tablet .
  • You should not use Methyzone Tablet if you have a bladder or bowel obstruction.
  • Methyzone Tablet is not approved for use by anyone younger than 18 years old. 
  • Prolonged use of Methyzone Tablet may cause gastrointestinal side effects due to increased gut peristalsis causing abdominal cramping, frequent bowel movements, or diarrhoea. However, these side effects can be managed with OTC items antidiarrheal preparations. 

Diet & Lifestyle Advise

  • Maintain a healthy weight. Include vegetables, fruits and grains in your diet.
  • Diet low in fat, saturated fat and cholesterol would be helpful.
  • Use salt and sugars in moderation.
  • Avoid consumption of alcohol.
  • Avoid processed and fried foods.
  • Try eating soft, mashed, or pureed foods as they are easy to swallow.
  • Avoid dry, chunky and chewy foods.
  • Regularly sip water during meals and snacks as it helps to moisten and soften the food. 
  • Add thickening agents to liquid foods as liquid foods may get into the lungs and cause choking.
  • Be careful while swallowing foods and liquids.

Methyzone Tablet Substitute

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