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Mifegest Kit contains Mifepristone and Misoprostol. Mifepristone works by blocking the effect of progesterone (female hormone), which is needed to sustain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped. Misoprostol is a prostaglandin analogue that helps increase uterine contractions and relaxes the cervix. Misoprostol should be taken 24-36 hours after taking mifepristone, either orally or vaginally.
No, Mifegest Kit should be taken in the dose and duration as advised by the doctor. Taking it in more than the recommended dose might cause unpleasant side effects like excessive uterine or vaginal bleeding.
No, Mifegest Kit is not known to affect any future chances of pregnancy. Mifegest Kit is used for medical abortion of early or unwanted pregnancy.
After taking Mifegest Kit, you may or may not experience vaginal bleeding, which does not indicate complete abortion. Your doctor will examine with the performing ultrasonography to confirm if the abortion is complete.
Do not take Mifegest Kit, if you have a heart fitted with an artificial valve, heart diseases like high blood pressure or high blood cholesterol levels (increased fat in your blood), have asthma, have blood clot problems, have a bleeding disorder, have liver or kidney disease, have anaemia (low haemoglobin) or otherwise malnourished. Taking Mifegest Kit in these conditions can cause life-threatening conditions in an individual.
Alcohol
Unsafe
Alcohol is known to cause excessive drowsiness and increases uterine bleeding if taken along with Mifegest Kit.
Pregnancy
Unsafe
Mifegest Kit is used for medical abortion. If taken in pregnancy, it can lead to abortion.
Breast Feeding
Unsafe
Mifegest Kit should not be taken if breastfeeding as it may pass through the milk to the baby.
Driving
Unsafe
Driving is unsafe when taking Mifegest Kit as it might increase the risk of excessive bleeding.
Liver
Caution
Mifegest Kit to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.
Kidney
Caution
Mifegest Kit to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.
Children
Unsafe
Mifegest Kit is not recommended for children below the age of 12. The safety and effectiveness of Mifegest Kit have not been established in children due to limited testing of this drug on children by competent authorities worldwide. If necessary, your doctor will decide whether to give Mifegest Kit or not.
Product Substitutes
About Mifegest Kit
Mifegest Kit belongs to a group of gynaecological medications called ‘Abortifacient’ used for the medical termination of the pregnancy before 63 days after the first day of the last menses period. Mifegest Kit also works in the second trimester of pregnancy.
Mifegest Kit contains two medicines, namely: Mifepristone and Misoprostol. Mifepristone is an anti-hormone (anti-progestogen) that blocks the effects of the progesterone hormone required in women to continue the pregnancy. On the other hand, Misoprostol is a prostaglandin that increases the womb’s (uterus) contraction and dilates the cervix, thereby expelling the pregnancy. Thus, Mifegest Kit together cause termination of pregnancy and must be used one after the other for medical abortion.
A medical abortion generally involves 2-3 visits to a doctor or clinic, which includes giving medicines and then confirmation of termination of pregnancy. Following are the schedule involved in medical abortion:
In some cases, you may experience nausea, uterine cramps, vomiting, diarrhoea, infection following abortion, dizziness, and uterine bleeding. Most of these side effects of Mifegest Kit subside with time. But if vaginal bleeding does not stop, please visit the doctor immediately, as it requires immediate medical attention.
Mifegest Kit should not be stopped abruptly without consulting the doctor as it may lead to incomplete abortion. Inform your doctor before starting Mifegest Kit if you have had an ectopic pregnancy (when the womb grows in the fallopian tube), using an intrauterine device, or you are breastfeeding, any bleeding disorder or heart problem. Do not strenuous activities like running, heavy exercise, or driving to avoid excessive bleeding. The doctor will also check with ultrasound if the absorption is complete as no bleeding does not mean that abortion is complete.
Uses of Mifegest Kit
Medicinal Benefits
Mifegest Kit contains Mifepristone and Misoprostol. Mifepristone works by blocking the effect of progesterone (female hormone) needed to maintain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped. It takes approximately 24-48 hours for Mifegest Kit to show effect. Once it starts acting, you will experience uterine bleeding. But no uterine bleeding does not mean that the abortion is complete. On the other hand, the second medicine is Misoprostol, a prostaglandin analogue that helps increase uterine contractions and relaxes the cervix. Thus Together Mifegest Kit terminates the state of pregnancy. Misoprostol should be taken at least 24-36 hours after taking mifepristone, either orally or vaginally. This is a non-surgical method which is 90% successful.
Directions for Use
Side Effects of Mifegest Kit
Drug Warnings
Do not take Mifegest Kit if you are allergic to misoprostol and mifepristone, have a heart fitted with an artificial valve, have heart diseases like high blood pressure or high blood cholesterol levels (increased fat in your blood), have asthma, have blood clot problems, have a bleeding disorder, have liver or kidney disease, have anaemia (low haemoglobin) or otherwise malnourished. Taking Mifegest Kit in these conditions can cause life-threatening conditions in an individual. Mifegest Kit is known to cause sleepiness, so driving or operating machinery should not be done. If you use contraceptive devices like the intrauterine device (IUD), please remove it before taking Mifegest Kit. Regular follow-up with the doctor is required for constant monitoring of abortion. If medical termination does not happen or becomes unsuccessful, it should be terminated surgically as it can lead to foetal defects. Your doctor will examine by performing ultrasonography to confirm if the abortion is complete. St John’s Wort (a natural remedy used to treat mild depression) grapefruit juice should not be taken when taking Mifegest Kit as it is known to interact.
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