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Written By ,
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

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Not for online sale
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Whats That

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Composition :

MIFEPRISTONE-25MG

Manufacturer/Marketer :

Pharmanova Specialties Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIPROGESTERONE

Country of origin

INDIA

Manufacturer/Marketer address

Unit 1B, Riddhi Siddhi, First Floor, Corporate Park, Opp. Sethia Surana Hospital, V N Purav Margh, Sion Trombay Road, Chembur, Mumbai – 400 071.
Other Info - MIF0035

FAQs

No, Mifeone 25mg Softgel Capsule should be taken in the dose and duration as advised by the doctor. Taking it in more than the recommended dose might cause unpleasant side effects like excessive uterine bleeding.

No, the Mifeone 25mg Softgel Capsule is not known to affect any future chances of fertility. Mifeone 25mg Softgel Capsule is used for medical abortion.

If you miss a dose of Mifeone 25mg Softgel Capsule , take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.

After taking Mifeone 25mg Softgel Capsule , you may or may not experience vaginal bleeding, which does not indicate complete abortion. Your doctor will examine with the performing ultrasonography to confirm if the abortion is complete.

No, the Mifeone 25mg Softgel Capsule does not affect fertility. Use contraception during sexual intercourse as it may lead to unwanted pregnancy if you are not planning it.

Some of the common side effects of Mifeone 25mg Softgel Capsule are nausea, weakness, fever/chills, vomiting, headache, diarrhoea, and dizziness.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Alcohol is known to cause excessive drowsiness if taken along with Mifeone 25mg Softgel Capsule and increase uterine bleeding.

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Pregnancy

Unsafe

Mifeone 25mg Softgel Capsule is used for medical abortion. If taken in pregnancy, it can lead to abortion.

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Breast Feeding

Caution

Let your doctor know if you are a nursing mother before prescribing Mifeone 25mg Softgel Capsule ; your doctor will decide whether Mifeone 25mg Softgel Capsule can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Mifeone 25mg Softgel Capsule may reduce alertness or induce sleep and dizziness. If you experience these symptoms, don't drive or operate machinery.

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Liver

Caution

Mifeone 25mg Softgel Capsule to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Mifeone 25mg Softgel Capsule to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Mifeone 25mg Softgel Capsule is not recommended for children below the age of 12. The safety and effectiveness of Mifeone 25mg Softgel Capsule have not been established in children due to limited testing of this drug on children by competent authorities worldwide. If necessary, your doctor will decide whether to give Mifeone 25mg Softgel Capsule or not.

About Mifeone 25mg Softgel Capsule

Mifeone 25mg Softgel Capsule belongs to the class of medication called 'progestin antagonist' used in combination with Misoprostol to induce a medical abortion. Mifeone 25mg Softgel Capsule is primarily used to end an early pregnancy (lasting up to 70 days or less than this) or an unwanted pregnancy with medication help.

Mifeone 25mg Softgel Capsule contains Mifepristone, which works by blocking the effect of progesterone (female hormone), which is needed to sustain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped. It takes approximately 24-48 hours for Mifeone 25mg Softgel Capsule to show effect. Once it starts acting, you will experience uterine bleeding. But no uterine bleeding does not mean that the abortion is complete.

Having a medical abortion is a very emotional decision. You should be mentally prepared for all the risks a surgical absorption could lead to, like incomplete abortion, heavy and prolonged bleeding (which may last up to 30 days), fever, and digestive system discomfort. Also, if the medication does not work, it can lead to an unwanted ongoing pregnancy, leading to fetal defects. So, to avoid any complications, keep in regular touch with your doctor and do as advised.

Mifeone 25mg Softgel Capsule should be taken in dose and duration as advised by the doctor, preferably with food. It would be best to take it at a fixed time every day. It is a tablet and should be taken orally with a glass of water. In some cases, you may experience nausea, uterine cramps, vomiting, diarrhoea, infection following abortion, dizziness, and uterine bleeding. Most of these side effects of Mifeone 25mg Softgel Capsule subside with time. But if your vaginal bleeding does not, please visit the doctor immediately, and it requires immediate medical attention.

Mifeone 25mg Softgel Capsule should not be stopped abruptly without consulting the doctor as it may lead to incomplete abortion. Inform your doctor before starting Mifeone 25mg Softgel Capsule if you have or ever had an ectopic pregnancy (when the fetus grows in the fallopian tube), using an intrauterine device, or if you are breastfeeding, any bleeding disorder or heart problem. Do not do strenuous activities like running, heavy exercise, or driving to avoid excessive bleeding. The doctor will also check with ultrasound if the absorption is complete as no bleeding does not mean that abortion is complete.

Uses of Mifeone 25mg Softgel Capsule

Medical abortion

Medicinal Benefits Mweb

Medicinal Benefits

Mifeone 25mg Softgel Capsule contains Mifepristone, which is taken in a regimen with Misoprostol to induce medical abortion or terminate a pregnancy before 70 days. It works by blocking the effect of progesterone (female hormone) needed to sustain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped. It takes approximately 24-48 hours for Mifeone 25mg Softgel Capsule to show effect.

Directions for Use

Mifeone 25mg Softgel Capsule should be taken in dose and duration as prescribed by your doctor. Do not chew or crush it; swallow it as a whole.

Side Effects of Mifeone 25mg Softgel Capsule

  • Weakness
  • Nausea
  • Uterine cramps
  • Vomiting
  • Diarrhoea
  • Dizziness
  • Infection following abortion
  • Uterine bleeding

Drug Warnings

Women who have an ectopic pregnancy (a pregnancy outside of the uterus, problems with the adrenal glands (the glands near the kidneys), currently taking corticosteroid therapy (medications), have an allergic reaction to mifepristone, misoprostol or similar drugs, have bleeding problems or taking the blood-thinning drug (warfarin, clopidogrel, aspirin, heparin etc.) should not use Mifeone 25mg Softgel Capsule and contact doctor. After using Mifeone 25mg Softgel Capsule if you start feeling sleepy, do not drive or operate heavy machinery. If you use an intrauterine device (IUD), please remove it before taking the Mifeone 25mg Softgel Capsule . Regular follow-up with the doctor is required for constant monitoring of abortion. If medical termination does not happen or becomes unsuccessful, it should be terminated surgically as it can lead to foetal defects. Your doctor will examine by performing ultrasonography to confirm if the abortion is complete. St John’s Wort (herbal supplements to treat mild depression) and grapefruit juice should not be taken when taking Mifeone 25mg Softgel Capsule as it is known to interact. 

Drug-Drug Interactions

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MifepristoneRanolazine
Critical
MifepristoneDalteparin
Critical

Drug-Drug Interactions

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MifepristoneRanolazine
Critical
How does the drug interact with Mifeone 25mg Softgel Capsule:
When Mifeone 25mg Softgel Capsule is taken with Ranolazine, may cause an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Phenylbutazone with Ranolazine can lead to an interaction. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms such as dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop taking any medications without consulting a doctor.
MifepristoneDalteparin
Critical
How does the drug interact with Mifeone 25mg Softgel Capsule:
Combining Mifeone 25mg Softgel Capsule with Dalteparin can increase the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Dalteparin with Mifeone 25mg Softgel Capsule may possibly lead to an interaction, they can be taken if a doctor prescribes it. Emergency medical attention may be needed for persistent, excessive bleeding. Without consulting a doctor. Do not stop using any medications without talking to a doctor.
MifepristoneFondaparinux
Critical
How does the drug interact with Mifeone 25mg Softgel Capsule:
Using Mifeone 25mg Softgel Capsule together with fondaparinux may increase the risk and/or severity of vaginal bleeding in women

How to manage the interaction:
Taking Fondaparinux with Mifeone 25mg Softgel Capsule together is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
MifepristoneFluticasone furoate
Critical
How does the drug interact with Mifeone 25mg Softgel Capsule:
Using Fluticasone furoate with Mifeone 25mg Softgel Capsule can reduce the effect of fluticasone furoate.

How to manage the interaction:
Taking Fluticasone furoate with Mifeone 25mg Softgel Capsule is not recommended, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
MifepristoneFentanyl
Critical
How does the drug interact with Mifeone 25mg Softgel Capsule:
Taking fentanyl and Mifeone 25mg Softgel Capsule may significantly increase the blood levels of fentanyl, which may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Mifeone 25mg Softgel Capsule and fentanyl, they can be taken together if advised by a doctor. Do not stop using any medications without talking to your doctor.
MifepristoneFludrocortisone
Critical
How does the drug interact with Mifeone 25mg Softgel Capsule:
When Fludrocortisone is taken with Mifeone 25mg Softgel Capsule, it can increase the risk of side effects.

How to manage the interaction:
Taking Mifeone 25mg Softgel Capsule with Fludrocortisone is not recommended, but it can be taken if prescribed by the doctor. Do not stop using any medication without consulting a doctor.
MifepristoneMethylprednisolone
Critical
How does the drug interact with Mifeone 25mg Softgel Capsule:
When Methylprednisolone is taken with Mifeone 25mg Softgel Capsule, it may decrease the levels of Methylprednisolone, which may be less effective in treating your condition.

How to manage the interaction:
Taking Methylprednisolone with Mifeone 25mg Softgel Capsule is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
MifepristoneConivaptan
Critical
How does the drug interact with Mifeone 25mg Softgel Capsule:
When Mifeone 25mg Softgel Capsule is taken with Conivaptan, it may increase the risk of negative side effects.

How to manage the interaction:
Taking Mifeone 25mg Softgel Capsule with Conivaptan is not recommended as it leads to an interaction, but it can be taken if prescribed by the doctor. However, if you experience symptoms such as seizures(fits), difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
MifepristoneDabigatran etexilate
Critical
How does the drug interact with Mifeone 25mg Softgel Capsule:
When Mifeone 25mg Softgel Capsule is taken with Dabigatran etexilate, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Mifeone 25mg Softgel Capsule with Dabigatran etexilate is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
MifepristoneMesoridazine
Critical
How does the drug interact with Mifeone 25mg Softgel Capsule:
Co-administration of Mesoridazine with Mefipristone can increase the risk of an abnormal heart rhythm, low potassium levels in the body.

How to manage the interaction:
Taking Mesoridazine with Mifeone 25mg Softgel Capsule is not recommended, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, weakness, tiredness, drowsiness, confusion, painful muscle cramping, nausea, or vomiting, constipation, abdominal cramping, chest pain, and/or swelling in the legs or feet, get medical attention. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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MIFEPRISTONE-25MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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MIFEPRISTONE-25MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Grapefruit juice may increase the effects of Mifeone 25mg Softgel Capsule. Avoid consumption of grape juice while taking Mifeone 25mg Softgel Capsule. However, if you experience headache, dizziness, fatigue, nausea, vomiting, cramping, diarrhea, swelling, and high blood pressure, consult the doctor.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DEXAMETHASONE
  • KETOCONAZOLE
  • ITRACONAZOLE
  • ERYTHROMYCIN
  • RIFAMPICIN
  • PHENYTOIN
  • PHENOBARBITAL
  • CARBAMAZEPINE
  • CYCLOSPORINE
  • TACROLIMUS
  • SIROLIMUS
  • ERGOTAMINE

Habit Forming

No

Special Advise

  • Mifeone 25mg Softgel Capsule should not be used to end the pregnancy after ten weeks.
  • Contact your doctor immediately if you experience heavy vaginal bleeding after taking this medicine.

Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) of 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Quitting smoking and not drinking alcohol is the best strategy to lower the risk of any complications.
  • Avoid chronic stress and physical exercise like running, as it might increase vaginal bleeding.
  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
  • Get an ultrasound to check if the abortion is done completely to avoid unwanted complications.
  • Try to include heart-healthy omega-3 fatty acid-containing foods or drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.
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