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Written By Divya L , PharmaD
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Not Returnable

About Migralay Plus 5 Tablet SR

Migralay Plus 5 Tablet SR belongs to the class of 'anti-migraine drugs' primarily used to treat migraine. Migraine is a medical condition that involves severe throbbing pain or a pulsing sensation on one side of the head. Severe and recurrent headaches are one of the characteristic symptoms of migraine. Its symptoms include nausea, vomiting, difficulty speaking, numbness or tingling, and sensitivity to light and sound.

Migralay Plus 5 Tablet SR consists of 'Propranolol' (beta-blocker) and 'Flunarizine' (calcium channel blocker). Propranolol has anxiolytic (anxiety-reducing), anti-arrhythmic (treats abnormal heart rhythms), and antihypertensive (reduces blood pressure) properties. Propranolol works by reducing cerebral (brain) blood flow by directly acting on the brain's blood vessels. It also inhibits cortical spreading depression, electrical activity in the brain that causes pain and inflammation. It effectively treats and reduces the severity and frequency of migraine headaches. Flunarizine belongs to the class of calcium channel blockers. It improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused due to migraine. It is also used to treat vertigo (spinning sensation).

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Migralay Plus 5 Tablet SR include dry weight gain, slow heart rate, tiredness, depression, drowsiness, abnormal dreams, and cold extremities (hands and feet). These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you use any prescription and non-prescription medications you are taking, including other vitamins, before starting Migralay Plus 5 Tablet SR. Migralay Plus 5 Tablet SR may cause weight gain in some cases, so avoid eating junk and eat a healthy, balanced diet, including home-cooked food. Consult your doctor before taking Migralay Plus 5 Tablet SR if you are pregnant, planning for pregnancy or breastfeeding. Avoid consuming alcohol along with Migralay Plus 5 Tablet SR as it could lead to increased drowsiness.

Uses of Migralay Plus 5 Tablet SR

Migraine.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, crush or break it.

Medicinal Benefits

Migralay Plus 5 Tablet SR is used to treat migraine. It consists of 'Propranolol' and 'Flunarizine'. Propranolol is a beta-blocker and has anxiolytic (anxiety-reducing), anti-arrhythmic, and antihypertensive properties. It works by lowering cerebral (brain) blood flow and inhibits cortical spreading depression, electrical activity in the brain that causes pain and inflammation. It reduces the severity and frequency of migraine headaches. Flunarizine is a channel blocker that improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused due to migraine. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Inform your doctor if you have any history of liver or kidney diseases, breathing problems (asthma, bronchitis, emphysema), diabetes, heart failure, heart rhythm problems (sinus bradycardia, Wolff-Parkinson-White syndrome, atrioventricular block), overactive thyroid, blood circulation problems (Raynaud's disease), adrenal gland tumour (pheochromocytoma), depression, metabolic acidosis (excess acid in the blood), and myasthenia gravis (muscle weakness) before starting Migralay Plus 5 Tablet SR. Please consult your doctor if you are pregnant and planning to conceive if the doctor advised you Migralay Plus 5 Tablet SR. Avoid consuming alcohol along with Migralay Plus 5 Tablet SR as it could lead to increased dizziness and drowsiness.

Diet & Lifestyle Advise

  • Avoid chocolates, junk food, cheese, processed food, alcohol, and smoking. Instead, eat a healthy diet and do regular exercise to avoid weight gain caused due to Migralay Plus 5 Tablet SR.
  • Avoid loud music, extreme temperatures, bright lights, and noisy places as it can increase headache.
  • You can try increasing your mindfulness by doing yoga, meditation, mindfulness-based cognitive therapy, and stress reduction techniques.
  • Drink enough water to stay hydrated and limit or avoid alcohol and caffeine to relieve headaches.
  • Include a diet rich in whole grains, vegetables, and fruits. This is a healthier option than eating a lot of simple carbohydrates found in processed foods.
  • You can include antioxidants in your daily diet like ashwagandha, omega-3 fatty acids, green tea, and lemon balm.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Habit Forming

No

Therapeutic Class

ANTIMIGRAINE AGENTS

Author Details

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FAQs

Migralay Plus 5 Tablet SR is a combination of two drugs: Propranolol and Flunarizine. Migralay Plus 5 Tablet SR treats migraine by reducing the blood flow to the brain, and inhibits cortical spreading depression, electrical activity in the brain that causes pain and inflammation.

Migralay Plus 5 Tablet SR may sometimes cause weight gain during its prolonged use. It is always advised to maintain a well-balanced, healthy diet and exercise regularly.

Migralay Plus 5 Tablet SR does not work for a sudden migraine attack. It is helpful in only preventing new episodes of migraine headaches. Please let your doctor know if you have sudden attacks to be prescribed other suitable medications.

Migralay Plus 5 Tablet SR is contraindicated in asthma, slow heart rate, abnormal heart rhythms, heart conditions like AV (Atrioventricular) block or sick sinus syndrome, depression, and Parkinson's disease. Please consult your doctor before starting Migralay Plus 5 Tablet SR if you have a medical history.

Your doctor will prescribe Migralay Plus 5 Tablet SR to prevent any new episodes of migraine. Please do not stop taking this medicine unless advised by your doctor since it may lead to recurrent episodes of migraine. Migralay Plus 5 Tablet SR also contains Propranolol, and its sudden withdrawal may cause sweating, shaking, irregular heartbeat, and worsening of underlying angina or heart attack. Hence, do not stop using Migralay Plus 5 Tablet SR unless advised by your doctor.

Drug-Drug Interactions Checker List

  • ALPRAZOLAM
  • QUETIAPINE
  • ARIPIPRAZOLE
  • ZOLPIDEM
  • DIPHENHYDRAMINE
  • SERTRALINE
  • DULOXETINE
  • FLUOXETINE
  • CARBAMAZEPINE
  • PHENYTOIN

Special Advise

  • Let your doctor know that you are taking Migralay Plus 5 Tablet SR if you are undergoing any medical tests.
  • Beta-blockers like Propranolol can mask hypoglycaemia symptoms (low blood sugar) or hyperthyroidism (high thyroid levels).
  • It is advised to inform your doctor if you have diabetes or thyroid disease before using Migralay Plus 5 Tablet SR.
  • Beta-blockers can also cause changes in serum lipid profiles. Patients with pre-existing hyperlipidaemia (high lipid levels) should be closely monitored if using Migralay Plus 5 Tablet SR.

Disease/Condition Glossary

Migraine: It is a medical condition that involves severe throbbing pain or a pulsing sensation on one side of the head. Severe and recurrent headaches are one of the characteristic symptoms of migraine. Symptoms of migraine may include nausea, vomiting, difficulty speaking, numbness or tingling, and sensitivity to light and sound. Migraine can be triggered by various factors like foods (eggs, tomatoes, onions, dairy products, wheat, pasta, citrus fruits, nitrites found in foods, alcohol, and red wine), hormonal changes, sleep changes, stress, loud noises, and medications.

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