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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

MILNACIPRAN-25MG

Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

MISCELLANEOUS

Country of origin

India
Other Info - MI64732

FAQs

Milpran 25mg Capsule works by increasing the amount of natural substances, such as serotonin and norepinephrine, which help prevent the movement of pain signals in the brain. Thereby, it helps manage fibromyalgia.

Milpran 25mg Capsule may cause high blood pressure (hypertension). Regular monitoring of pulse rate and blood pressure prior to initiation and during treatment is recommended.

Do not discontinue the medicine without consulting your doctor. The doctor may reduce the dose gradually as stopping Milpran 25mg Capsule suddenly may cause withdrawal symptoms like mood changes, agitation, irritability, dizziness, confusion, tiredness, headache, numbness or tingling in the hands or feet, anxiety, difficulty falling asleep or staying asleep, abnormal excitement, seizures, or ringing in the ears. Consult the doctor if you experience these symptoms.

Milpran 25mg Capsule may cause angle-closure glaucoma. The doctor may advise an eye examination before you start taking Milpran 25mg Capsule. Consult the doctor immediately if you experience eye pain, nausea, swelling or redness in or around the eye, and changes in vision, such as seeing coloured rings around lights.

Disclaimer

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Alcohol

Unsafe

Avoid consuming alcohol while on treatment with Milpran 25mg Capsule.

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Pregnancy

Caution

Milnacipran belongs to pregnancy category C. Milpran 25mg Capsule should be used during pregnancy only if the benefits outweigh the risks.

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Breast Feeding

Caution

Caution should be exercised while administering Milpran 25mg Capsule to nursing women.

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Driving

Caution

Milpran 25mg Capsule may cause drowsiness and may affect your judgment, thinking, and movements. Avoid driving or operating machinery until you know how this medication affects you.

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Liver

Caution

Please consult your doctor if you have liver problems. Caution should be exercised in patients with severe liver impairment.

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Kidney

Caution

Dose adjustment may be needed in patients with severe renal impairment. It should be used with caution in patients with moderate kidney impairment. This medicine is not recommended for patients with end-stage renal disease.

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Children

Unsafe

Milpran 25mg Capsule is not recommended for children below 17 years as the safety and effectiveness have not been established.

About Milpran 25mg Capsule

Milpran 25mg Capsule belongs to the group of medicines known as selective serotonin and norepinephrine reuptake inhibitors (SNRIs) indicated for the management of fibromyalgia. Fibromyalgia is a long-lasting condition that causes pain and tenderness throughout the body.
 
Milpran 25mg Capsule contains Milnacipran, which works by increasing the amount of natural substances, such as serotonin and norepinephrine, which help stop the movement of pain signals in the brain. Thereby, it helps manage fibromyalgia.
 
In some cases, Milpran 25mg Capsule may cause side effects such as nausea, vomiting, headache, constipation, dizziness, and dry mouth. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if any of the side effects persist or worsen.
 
Consult the doctor if you are pregnant or breastfeeding. Milpran 25mg Capsule is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol while on treatment with Milpran 25mg Capsule. Keep the doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of Milpran 25mg Capsule

Fibromyalgia

Medicinal Benefits Mweb

Medicinal Benefits

Milpran 25mg Capsule belongs to the group of medicines called selective serotonin and norepinephrine reuptake inhibitors (SNRIs) used to treat fibromyalgia. Milpran 25mg Capsule contains Milnacipran, that works by increasing the amount of natural substances, such as serotonin and norepinephrine, which help stop the movement of pain signals in the brain. Thereby it helps manage fibromyalgia.

Directions for Use

Take Milpran 25mg Capsule with or without food. However, taking it with food may improve the tolerability of the drug and decrease the chance of stomach upset. Swallow the medicine as a whole with a glass of water; do not chew or crush it.

Side Effects of Milpran 25mg Capsule

  • Nausea
  • Vomiting
  • Headache
  • Constipation
  • Dizziness
  • Dry mouth
  • Insomnia (sleep disorder)

Drug Warnings

Do not take Milpran 25mg Capsule if you are allergic to any of its components. Inform the doctor if you have high blood pressure, seizures, irregular heartbeat, abnormal bleeding, inflamed or enlarged prostate, low sodium levels, liver or kidney problems, or if you have taken monoamine oxidase inhibitors in the last 14 days. Consult the doctor if you are pregnant or breastfeeding. This medicine is not recommended for children. Avoid consumption of alcohol during treatment with Milpran 25mg Capsule. Let the doctor know if you take any other medications, including herbal supplements.

Drug-Drug Interactions

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MilnacipranSafinamide
Critical
MilnacipranVenlafaxine
Severe

Drug-Drug Interactions

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MilnacipranSafinamide
Critical
How does the drug interact with Milpran 25mg Capsule:
Taking Safinamide with Milpran 25mg Capsule can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Milpran 25mg Capsule is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
MilnacipranVenlafaxine
Severe
How does the drug interact with Milpran 25mg Capsule:
When venlafaxine is taken with Milpran 25mg Capsule, it can cause serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although there is a possible interaction between Venlafaxine and Milpran 25mg Capsule, you can take these medicines together if prescribed by a doctor. However, if you experience any of the following symptoms: confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhoea, seek immediate medical attention. Do not discontinue any medications without consulting a doctor.
MilnacipranOndansetron
Severe
How does the drug interact with Milpran 25mg Capsule:
When ondansetron, is taken with Milpran 25mg Capsule it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of ondansetron along with Milpran 25mg Capsule can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
MilnacipranVilazodone
Severe
How does the drug interact with Milpran 25mg Capsule:
When Vilazodone is taken with Milpran 25mg Capsule, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Vilazodone and Milpran 25mg Capsule, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
MilnacipranVortioxetine
Severe
How does the drug interact with Milpran 25mg Capsule:
Co-administration of Vortioxetine with Milpran 25mg Capsule can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Vortioxetine with Milpran 25mg Capsule together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, it's a good idea to reach out to a doctor right away. Do not discontinue any medications without consulting a doctor.
MilnacipranParoxetine
Severe
How does the drug interact with Milpran 25mg Capsule:
Combining Paroxetine with Milpran 25mg Capsule can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a possible interaction between Paroxetine and Milpran 25mg Capsule, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, diarrhea, contact your doctor right away. Do not stop using any medications without talking to your doctor.
MilnacipranPentazocine
Severe
How does the drug interact with Milpran 25mg Capsule:
Taking Pentazocine with Milpran 25mg Capsule may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
There may be a possibility of interaction between Pentazocine and Milpran 25mg Capsule, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
MilnacipranSumatriptan
Severe
How does the drug interact with Milpran 25mg Capsule:
Using Milpran 25mg Capsule together with Sumatriptan might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although there is a possible interaction between Sumatriptan and Milpran 25mg Capsule, you can take these medicines together if prescribed by your doctor. However, if you experience increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea call a doctor. Do not discontinue any medications without consulting a doctor.
MilnacipranDoxepin
Severe
How does the drug interact with Milpran 25mg Capsule:
The combined use of Milpran 25mg Capsule and Doxepin can increase the risk of serotonin syndrome(A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Milpran 25mg Capsule and Doxepin can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, diarrhoea, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
MilnacipranSelegiline
Severe
How does the drug interact with Milpran 25mg Capsule:
When Milpran 25mg Capsule is taken with Selegiline, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Milpran 25mg Capsule and Selegiline, but it can be taken if prescribed by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhoea, consult the doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Habit Forming

No

Special Advise

  • Consult the doctor immediately if you have thoughts of harming yourself or ending your life.
  • Seek medical attention if you experience extreme worry, panic attacks, agitation, difficulty falling asleep or staying asleep, aggressive behaviour, irritability, acting without thinking, severe restlessness, and frenzied, abnormal excitement. 
  • If you are due to undergo any surgery or dental treatment, inform the person doing the tests that you are taking Milpran 25mg Capsule.

Diet & Lifestyle Advise

  • Eat a balanced diet rich in fresh fruits, vegetables, whole grains, healthy fats, low-fat dairy, and lean protein.
  • Avoid saturated fats and processed or fried food.
  • Limit the amount of sugar and salt in your diet.
  • Foods that trigger symptoms should be avoided.
  • Maintain a moderate weight by eating a healthy diet.

Milpran 25mg Capsule Substitute

Substitutes safety advice
  • Acmil 25mg Capsule 10's

    by Others

    3.87per tablet
  • MILNACE 25MG CAPSULE

    by Others

    5.63per tablet
  • MILZA 25MG CAPSULE

    by Others

    3.45per tablet
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