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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sureshvarma D , MPharma
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer :

Msn Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTICHOLINERGICS

Country of origin

INDIA

Manufacturer/Marketer address

MSN Laboratories Pvt.Ltd., MSN House, Plot No: C-24, Industrial Estate, Sanathnagar, Hyderabad - 18 Telangana, INDIA
Other Info - MIR0193

Author Details

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FAQs

Mirabig-S 50 Combikit contains Solifenacin and Mirabegron. Solifenacin reduces the undesirable contractions of the bladder, thereby increasing the amount of urine that the bladder can hold. This decreases the urgency for urination. Mirabegron relaxes the muscles of the bladder; this prevents frequent, uncontrolled, or urgent urination. Together, Mirabig-S 50 Combikit helps in treating an overactive bladder.

There is some overlap between the symptoms of both OAB and BPH. OAB occurs due to uncontrolled urinary bladder muscle contractions. The main symptom of OAB is a sudden urge to urinate that's hard to control, which is stressful. On the other hand, BPH occurs due to an enlarged prostate gland, which puts pressure on the urinary bladder, thereby causing pain during urination.

Dry mouth could be a side effect of Mirabig-S 50 Combikit. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol; drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Mirabig-S 50 Combikit might cause hypertension. Therefore, consult your doctor before taking Mirabig-S 50 Combikit if you have high blood pressure.

Constipation could be a side-effect of Mirabig-S 50 Combikit. Eat fibre-rich food and drink plenty of fluids if you experience constipation. Talk to your doctor if you have severe constipation.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

You are recommended to avoid or limit alcohol consumption while taking Mirabig-S 50 Combikit as it may cause increased dizziness.

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Pregnancy

Caution

Limited information is available regarding the usage of Mirabig-S 50 Combikit during pregnancy. Consult your doctor before taking Mirabig-S 50 Combikit if you are pregnant.

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Breast Feeding

Caution

Limited information is available regarding the usage of Mirabig-S 50 Combikit during breastfeeding. Consult your doctor before taking Mirabig-S 50 Combikit if you are breastfeeding.

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Driving

Caution

Mirabig-S 50 Combikit may cause blurred vision and tiredness. Drive or operate machinery only if you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Mirabig-S 50 Combikit is not recommended for children as safety and effectiveness have not been established.

About Mirabig-S 50 Combikit

Mirabig-S 50 Combikit is a combination medicine used to treat overactive bladder (OAB) with symptoms of urinary incontinence (urine leakage), urgent or frequent urination, increased night-time urination, and dysuria (painful or difficult urination). Overactive bladder is a condition in which there is a problem with bladder function, which causes a sudden urge to urinate that might be difficult to control.
 
Mirabig-S 50 Combikit contains Solifenacin (anti-cholinergic) and Mirabegron (beta-3 adrenergic agonist). Solifenacin reduces the undesirable contractions of the bladder, thereby increasing the amount of urine that the bladder can hold. This decreases the urgency for urination. Mirabegron relaxes the muscles of the bladder; this prevents frequent, uncontrolled, or urgent urination. Together, Mirabig-S 50 Combikit helps in treating overactive bladder.
 
You are advised to take Mirabig-S 50 Combikit for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience common side-effects such as dry mouth, constipation, headache, high blood pressure, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Mirabig-S 50 Combikit is not recommended for children as safety and efficacy have not been established. Mirabig-S 50 Combikit may cause blurred vision, so drive with caution. Avoid or limit alcohol consumption along with Mirabig-S 50 Combikit as it could lead to increased dizziness. Inform your doctor about your health condition and medications before taking Mirabig-S 50 Combikit to rule out any side effects/interactions.

Uses of Mirabig-S 50 Combikit

Overactive bladder syndrome

Medicinal Benefits Mweb

Medicinal Benefits

Mirabig-S 50 Combikit is a combination of two drugs, namely: Solifenacin and Mirabegron. Mirabig-S 50 Combikit is a combination medicine used to treat overactive bladder (OAB) with symptoms of urinary incontinence (urine leakage), urgent or frequent urination, increased night-time urination, dysuria (painful or difficult urination). Solifenacin is an anti-cholinergic that reduces the undesirable contractions of the bladder, thereby increasing the amount of urine that the bladder can hold. This decreases the urgency for urination. Mirabegron is a beta-3 adrenergic agonist which relaxes the muscles of the bladder; this prevents frequent, uncontrolled, or urgent urination. Together, Mirabig-S 50 Combikit helps in treating an overactive bladder.

Directions for Use

Swallow Mirabig-S 50 Combikit as a whole with water; do not chew or break it.

Side Effects of Mirabig-S 50 Combikit

  • Constipation
  • Headache 
  • Dry mouth
  • Blurred vision
  • Vomiting
  • High blood pressure
  • Urinary tract infection

Drug Warnings

Do not take Mirabig-S 50 Combikit if you are allergic to any of its contents. Inform your doctor if you have glaucoma, myasthenia gravis, ulcerative colitis, urinary retention, high blood pressure, angioedema, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Mirabig-S 50 Combikit is not recommended for children. Mirabig-S 50 Combikit may cause blurred vision, so drive with caution. Avoid or limit alcohol consumption with Mirabig-S 50 Combikit as it could lead to increased dizziness. 

Drug-Drug Interactions

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MirabegronEliglustat
Critical
SolifenacinMesoridazine
Critical

Drug-Drug Interactions

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MirabegronEliglustat
Critical
How does the drug interact with Mirabig-S 50 Combikit:
Coadministration of Eliglustat and Mirabig-S 50 Combikit can significantly increase the blood levels of eliglustat. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Mirabig-S 50 Combikit with Eliglustat is not recommended, it should be taken only when advised by a doctor. You should seek immediate medical help if you develop symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, irregular heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without a doctor's advice.
SolifenacinMesoridazine
Critical
How does the drug interact with Mirabig-S 50 Combikit:
Using Mesoridazine together with Mirabig-S 50 Combikit can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mesoridazine with Mirabig-S 50 Combikit is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations call a doctor.
SolifenacinPotassium chloride
Critical
How does the drug interact with Mirabig-S 50 Combikit:
Taking Mirabig-S 50 Combikit and Potassium chloride together can increase the risk of stomach ulcers, bleeding, and stomach injury.

How to manage the interaction:
Taking Mirabig-S 50 Combikit with Potassium chloride is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
SolifenacinItraconazole
Critical
How does the drug interact with Mirabig-S 50 Combikit:
The blood levels and effects of Mirabig-S 50 Combikit may be greatly increased when combined with itraconazole.

How to manage the interaction:
Mirabig-S 50 Combikit and Itraconazole may interact, however, if recommended by a physician, they are safe to consume. Consult a doctor if you feel sleepy, or uneasy, have an irregular heartbeat, have blurry vision, have trouble urinating, have a dry mouth, a headache, have digestive problems, or have constipation. Without consulting a doctor, never stop taking any medication.
MirabegronBrexpiprazole
Severe
How does the drug interact with Mirabig-S 50 Combikit:
A combined use of Mirabig-S 50 Combikit and Brexpiprazole may increase the level of Brexpiprazole in blood. This can increase the risk or severity of side effects.

How to manage the interaction:
There could be a possible interaction between Mirabig-S 50 Combikit and Brexpipraole, it can be taken together if your doctor has advised them. However, if you experience drowsiness, fatigue, seizure, chest pain or tightness, irregular heart rates, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramp, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MirabegronTamoxifen
Severe
How does the drug interact with Mirabig-S 50 Combikit:
Coadministration of Mirabig-S 50 Combikit and Tamoxifen may reduce the effects of tamoxifen.

How to manage the interaction:
Taking Mirabig-S 50 Combikit and Tamoxifen together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience painful urination, constipation, dry mouth, headache, sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MirabegronVenetoclax
Severe
How does the drug interact with Mirabig-S 50 Combikit:
Coadministration of Mirabig-S 50 Combikit and Venetoclax may significantly increase the blood levels and effects of Venetoclax. This can increase the risk or severity of side effects.

How to manage the interaction:
There may be a possible interaction between Mirabig-S 50 Combikit and Venetoclax, but they can be taken together if your doctor has prescribed them. However, if you experience nausea, vomiting, diarrhea, fatigue, fever, chills, bleeding problems, sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MirabegronAripiprazole
Severe
How does the drug interact with Mirabig-S 50 Combikit:
Combining Aripiprazole with Mirabig-S 50 Combikit can increase the levels of Aripiprazole in the body. This can lead to increased risk or severity of side effects.

How to manage the interaction:
Although taking Mirabig-S 50 Combikit and Aripiprazole together can cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs like feeling sleepy, having seizures, unusual muscle movements, low blood pressure, feeling confused, muscle spasms, twitching in your jaw, shaking or jerking in your arms and legs, feeling nervous or restless, dizziness, lightheaded, or fainting contact the doctor right away. Do not stop using any medications without a doctor's advice.
MirabegronPimozide
Severe
How does the drug interact with Mirabig-S 50 Combikit:
Combined use of Mirabig-S 50 Combikit and Pimozide may increase the level of pimozide in the blood. This can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Mirabig-S 50 Combikit and Pimozide may lead to an interaction but they can be taken together if your doctor has prescribed them. However, if you experience drowsiness, blurred vision, dry mouth, constipation, low blood pressure, tremors, trembling of hands, arms, legs, jaw and face, balance and Speech difficulty, or abnormal muscle movements consult a doctor. Do not discontinue any medications without consulting a doctor.
MirabegronThioridazine
Severe
How does the drug interact with Mirabig-S 50 Combikit:
Combine use of Mirabig-S 50 Combikit and thioridazine may raise the blood levels of thioridazine. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Mirabig-S 50 Combikit and thioridazine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience stomach pain, diarrhea, dehydration, sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • METOPROLOL
  • ACETAMINOPHEN
  • ALBUTEROL

Habit Forming

No

Diet & Lifestyle Advise

  • Pelvic floor exercises would be helpful in treating bladder spasms.
  • Avoid foods like sugars, carbonated beverages, tea, citrus fruits, tomatoes, spicy foods, chocolate and tea. 
  • Avoid drinking excess alcohol or caffeinated drinks, as they can worsen the symptoms.
  • Maintain a healthy weight, and exercise regularly.
  • Quit smoking.
  • Take 6-8glasses of liquids every day.
  • Avoid processed foods. Instead, choose whole, unprocessed foods.
  • Include fruits, vegetables, and fibre-rich food in your diet.

Mirabig-S 50 Combikit Substitute

Substitutes safety advice
  • Mirago-S 50 Tablet 10's

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    54.09per tablet
  • Megatas-S 50 Tablet 10's

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    56.66per tablet
  • Mirbeg-S 50 Tablet 10's

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    54.54per tablet
  • Bladmir-S 50 Tablet 10's

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    53.96per tablet
  • Lupin Mira-S 50 Tablet 10's

    by Others

    59.85per tablet
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