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Reviewed By Sureshvarma D , MPharma
48 Hrs returnable
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Whats That

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Composition :

EVEROLIMUS-0.5MG

Manufacturer/Marketer :

Natco Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTINEOPLASTIC

Country of origin

India

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Other Info - NAT0658

FAQs

Natlimus 0.5 mg Tablet is an anticancer medicine. It belongs to a group of medicines known as a kinase inhibitor. It works by lowering the blood supply to the tumor, which reduces the growth and spread of cancer cells.

There is no specific duration of treatment with Natlimus 0.5 mg Tablet . Natlimus 0.5 mg Tablet is continued till benefit is seen or undesirable toxicity or side effects occur.

You should prevent grapefruit or grapefruit juice while taking Natlimus 0.5 mg Tablet . This is because taking them together may rise the levels of Natlimus 0.5 mg Tablet in your blood to toxic levels. Avoid the use of live vaccinations and any probable contact with people who have received live vaccinations.

Natlimus 0.5 mg Tablet can lead to serious side effects that consist of severe allergic reactions, angioedema (painless swelling under the skin) and kidney failure which can be dangerous and can lead to death. It is possible that you may develop an infection or problems associated to lungs like breathing problems.

It usually takes three to six months for most types of lung cancer to double their size. It will take a long time for lung cancer to reach a size that could be diagnosed in X-Ray.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Natlimus 0.5 mg Tablet to avoid unpleasant side-effects.

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Pregnancy

Unsafe

Natlimus 0.5 mg Tablet is belonging to pregnancy C category. It is not safe in pregnancy as it may causes harm to the unborn baby. Do not conceive a baby while taking Natlimus 0.5 mg Tablet .

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Breast Feeding

Unsafe

Natlimus 0.5 mg Tablet should not be taken by breastfeeding mothers as it may harm to the new-born baby.

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Driving

Caution

Natlimus 0.5 mg Tablet may cause tiredness (fatigue), do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Natlimus 0.5 mg Tablet should be taken with caution in patients dealing with liver disease. The doctor may adjust the dose according to the medical condition of the patient.

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Kidney

Caution

Natlimus 0.5 mg Tablet is likely unsafe in patients with severe kidney disease as it may cause kidney failure which can be dangerous, use Natlimus 0.5 mg Tablet only when prescribed by a doctor.

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Children

Unsafe

Natlimus 0.5 mg Tablet is not recommended for children below 18 years as the safety and effectiveness were not established.

About Natlimus 0.5 mg Tablet

Natlimus 0.5 mg Tablet belongs to the group of medicine called ‘anti-cancer’. It is primarily used to treat breast cancer, pancreatic cancer, lung cancer and kidney cancer. Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen. Pancreatic cancer is described as a cancerous growth in the pancreas which normally begins in the cells that generate the juices that help break down food and the hormones which help in controlling blood sugar levels. Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. 

Natlimus 0.5 mg Tablet contains 'Everolimus' which belongs to the group of medicines known as 'kinase inhibitors'. It works by decreases the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells.

Take Natlimus 0.5 mg Tablet as prescribed by your doctor. You are advised to take Natlimus 0.5 mg Tablet for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience weakness, infection, sinus inflammation, cough, diarrhea, fever, fatigue, otitis media (infection of the ear), stomatitis (Inflammation of the mouth) and upper respiratory tract infection. Most of these side effects of Natlimus 0.5 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

To treat your condition effectually, continue taking Natlimus 0.5 mg Tablet for as long as your doctor has prescribed. If you are known to be allergic to Natlimus 0.5 mg Tablet or any other medicines, please tell your doctor. Do not take Natlimus 0.5 mg Tablet if you are pregnant or planning for pregnancy as Natlimus 0.5 mg Tablet may harm the unborn baby. Natlimus 0.5 mg Tablet should not be taken by breastfeeding mothers as it may cause harm to the newborn baby. Natlimus 0.5 mg Tablet causes tiredness, thus, it is advisable not to drive unless you are alert. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition.

Uses of Natlimus 0.5 mg Tablet

Breast cancer, pancreatic cancer, lung cancer and kidney cancer.

Medicinal Benefits Mweb

Medicinal Benefits

Natlimus 0.5 mg Tablet is indicated to the patients dealing with breast cancer, pancreatic cancer, lung cancer, kidney cancer and stomach/ intestinal cancer. Cancer of this type tends to spread quickly in other parts of the body. Natlimus 0.5 mg Tablet travels through the bloodstream and effectively destroys cancerous cells and other parts of the body. It works by decreases the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells. Besides this, it is also effective in people with genetic disorders to treat some types of tumors in the brain or kidney.

Directions for Use

Take Natlimus 0.5 mg Tablet with or without food as advised by the doctor. Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Natlimus 0.5 mg Tablet

  • Tiredness
  • Breathlessness
  • Dizziness
  • Headache
  • Loss of appetite
  • Infection
  • Mouth ulcers 
  • Sinus inflammation
  • Cough
  • Diarrhea
  • Fever
  • High level of sugar in the blood (hyperglycemia)
  • Signs of low level of red blood cells (anemia) 
  • Otitis media (infection of the ear)
  • Stomatitis (Inflammation of the mouth)
  • Upper respiratory tract infection.
  • Swelling of arms, hands, feet, and ankles

Drug Warnings

If you are known to be allergic to Natlimus 0.5 mg Tablet or any other medicines, please tell your doctor. Natlimus 0.5 mg Tablet should not be taken in the conditions like liver disease, diabetes and high level of cholesterol. Do not take Natlimus 0.5 mg Tablet if you have recent surgery, infection and hepatitis B. Natlimus 0.5 mg Tablet may weaken your immune system, inform your doctor before taking Natlimus 0.5 mg Tablet . Natlimus 0.5 mg Tablet may also impair your kidney function. Therefore, monitor your kidney function regularly while taking Natlimus 0.5 mg Tablet . Natlimus 0.5 mg Tablet may cause cough, fever and shortness of breathing, thereby inform your doctor while taking your Natlimus 0.5 mg Tablet . Natlimus 0.5 mg Tablet may cause skin cancer, if you observe night sweating, weight loss, or change in color and size of the mole inform your doctor. Do not take Natlimus 0.5 mg Tablet if you are pregnant or planning for pregnancy as Natlimus 0.5 mg Tablet may harm the unborn baby. Natlimus 0.5 mg Tablet should not be taken by breastfeeding mothers as it may cause harm to the newborn baby. Natlimus 0.5 mg Tablet causes tiredness, thus, it is advisable not to drive unless you are alert. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition.

Drug-Drug Interactions

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EverolimusIdelalisib
Severe
EverolimusTenofovir alafenamide
Severe

Drug-Drug Interactions

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EverolimusIdelalisib
Severe
How does the drug interact with Natlimus 0.5 mg Tablet:
Taking Natlimus 0.5 mg Tablet with idelalisib can considerably raise blood levels of Natlimus 0.5 mg Tablet, increasing the risk of serious side effects (pneumonitis - lung inflammation, infection, mouth ulcers, anemia, or bleeding).

How to manage the interaction:
Co-administration of Natlimus 0.5 mg Tablet with Idelalisib can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
EverolimusTenofovir alafenamide
Severe
How does the drug interact with Natlimus 0.5 mg Tablet:
Tenofovir alafenamide can cause kidney issues, and taking it with Natlimus 0.5 mg Tablet, can enhance the risk.

How to manage the interaction:
Although there is a possible interaction between Natlimus 0.5 mg Tablet and Tenofovir alafenamide, you can take these medicines together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not stop using any medications without talking to a doctor.
EverolimusVoclosporin
Severe
How does the drug interact with Natlimus 0.5 mg Tablet:
Using voclosporin together with Natlimus 0.5 mg Tablet may increase the risk of serious infections.

How to manage the interaction:
Although taking Natlimus 0.5 mg Tablet and Voclosporin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EverolimusKetorolac
Severe
How does the drug interact with Natlimus 0.5 mg Tablet:
Coadministration of Natlimus 0.5 mg Tablet with ketorolac may increase the risk of kidney problems.

How to manage the interaction:
Although taking Ketorolac and Natlimus 0.5 mg Tablet together can result in an interaction, but it can be taken if a doctor has prescribed it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, swelling, breathing difficulty, pain, weakness, tiredness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without consulting a doctor.
EverolimusPhenobarbital
Severe
How does the drug interact with Natlimus 0.5 mg Tablet:
Phenobarbital can drastically lower Natlimus 0.5 mg Tablet levels in the blood, making the medicine less effective in treating the illness.

How to manage the interaction:
Although taking phenobarbital with Natlimus 0.5 mg Tablet can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
EverolimusIohexol
Severe
How does the drug interact with Natlimus 0.5 mg Tablet:
Injections of iohexol and related contrast agents can occasionally cause kidney damage, and mixing them with other medication that might adversely harm the kidney, such as Natlimus 0.5 mg Tablet, may enhance the risk.

How to manage the interaction:
Taking Natlimus 0.5 mg Tablet with Iohexol together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, If you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult your doctor immediately. Drink lots of fluid after the procedure to stay hydrated and to flush the contrast agent out of your kidneys. Do not stop using any medications without first talking to your doctor.
EverolimusFosphenytoin
Severe
How does the drug interact with Natlimus 0.5 mg Tablet:
Taking Natlimus 0.5 mg Tablet and Fosphenytoin may reduce the blood levels of Natlimus 0.5 mg Tablet, which may make it less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Natlimus 0.5 mg Tablet and Fosphenytoin, you can take these medicines together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EverolimusDarunavir
Severe
How does the drug interact with Natlimus 0.5 mg Tablet:
Taking Natlimus 0.5 mg Tablet with Darunavir can considerably raise blood levels of Natlimus 0.5 mg Tablet, increasing the risk of serious side effects (pneumonitis - lung inflammation, infection, mouth ulcers, anemia, or bleeding).

How to manage the interaction:
Although there is a possible interaction between Darunavir and Natlimus 0.5 mg Tablet, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
EverolimusMeloxicam
Severe
How does the drug interact with Natlimus 0.5 mg Tablet:
Co-administration of Natlimus 0.5 mg Tablet with Meloxicam can increase the risk of kidney problems.

How to manage the interaction:
Although taking Natlimus 0.5 mg Tablet and Meloxicam together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience things like nausea, vomiting, loss of appetite, weight loss, swelling, muscle cramps, weakness, dizziness, confusion, or an irregular heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EverolimusFingolimod
Severe
How does the drug interact with Natlimus 0.5 mg Tablet:
When Natlimus 0.5 mg Tablet is used with Fingolimod, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Natlimus 0.5 mg Tablet and Fingolimod, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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EVEROLIMUS-0.5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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EVEROLIMUS-0.5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Taking Natlimus 0.5 mg Tablet with grapefruit juice can raise blood levels and enhance the effects of Natlimus 0.5 mg Tablet. Since the co-administration of Natlimus 0.5 mg Tablet along with grapefruit juice can lead to an interaction, You should not consume grapefruit juice or eat grapefruits while taking Natlimus 0.5 mg Tablet.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • ERYTHROMYCIN
  • RITONAVIR
  • EFAVIRENZ
  • RAMIPRIL
  • VERAPAMIL
  • DILTIAZEM
  • DRONEDARONE
  • IMATINIB
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • FLUCONAZOLE

Habit Forming

No

Special Advise

  • Natlimus 0.5 mg Tablet should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Natlimus 0.5 mg Tablet .
  • Do not have immunizations/vaccinations without a doctor's advice.
  • Avoid contact with people who have recently received live vaccines.

Diet & Lifestyle Advise

  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yogurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep, rest well.
  • Performing yoga and other relaxation techniques may also improve physical and mental health and may reduce your stress levels.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

Natlimus 0.5 mg Tablet Substitute

Substitutes safety advice
  • Certican 0.5 Tablet 10's

    by Others

    200.20per tablet
  • Evergraf 0.5 Tablet 10's

    by Others

    141.35per tablet
  • Advacan 0.5 mg Tablet 10's

    by Others

    98.55per tablet
  • Lanolimus 0.5 mg Tablet 10's

    by Others

    66.51per tablet
  • Everotas 0.5 mg Tablet 10's

    by Others

    87.39per tablet
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