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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

PRALIDOXIME-500MG

Manufacturer/Marketer :

Troikaa Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Neopam 500mg Injection

Neopam 500mg Injection belongs to the oxime class of drugs. Pralidoxime is used alone or together with atropine to treat poisoning caused by organic phosphorus pesticides or chemicals. It is also used to treat an overdose of drugs that treat myasthenia gravis.

Neopam 500mg Injection contains Pralidoxime, a cholinesterase reactivator. It works by reactivating the enzyme cholinesterase (mainly outside the central nervous system), which has been inactivated by phosphorylation due to an organophosphate pesticide or related compound.

A qualified healthcare professional will administer Neopam 500mg Injection. You may experience mild to moderate pain at the site of injection, blurred vision, diplopia (double vision), impaired accommodation, dizziness, headache, drowsiness, nausea, tachycardia (fast heartbeat), increased systolic and diastolic blood pressure, hyperventilation (rapid or deep breathing), and muscular weakness. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, inform your doctor.

Before taking Neopam 500mg Injection, let your doctor know about all your medical conditions, sensitivities, and ongoing medications. Also, inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Neopam 500mg Injection may cause blurred vision and diplopia (double vision); it impacts your ability to drive or operate machinery.

Uses of Neopam 500mg Injection

Organophosphate poisoning

Directions for Use

A qualified healthcare professional will administer Neopam 500mg Injection.

Medicinal Benefits

Neopam 500mg Injection contains Pralidoxime, a cholinesterase reactivator that belongs to the oxime class of drugs. Pralidoxime is together with another medicine called atropine to treat poisoning caused by organic phosphorus pesticides (such as diazinon, malathion, sarin and parathion). Pralidoxime injection is also used to treat an overdose of medicines (such as neostigmine, ambenonium, and pyridostigmine) that treat myasthenia gravis. It works by reactivating the enzymes (cholinesterase) blocked by many pesticides or medicines. Poisoning with these substances or drugs weakens your muscles, including those that let you breathe. Pralidoxime is used to help you regain muscle strength.

Storage

Store in a cool and dry place away from sunlight
Side effects of Neopam 500mg Injection
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Drug Warnings

Neopam 500mg Injection is not recommended as an antidote for carbamate pesticide overdose since it may enhance carbaryl toxicity or known hypersensitivity to the drug. Before taking Neopam 500mg Injection, inform your doctor of all your medical problems, sensitivities, and medicines. Also, let your doctor know if you are pregnant, want to become pregnant, or are breastfeeding. Do not drive or operate machinery because Neopam 500mg Injection may cause diplopia (double vision), decreased accommodation, and dizziness.

Drug-Drug Interactions

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PralidoximePramlintide
Critical

Drug-Drug Interactions

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PralidoximePramlintide
Critical
How does the drug interact with Neopam 500mg Injection:
Neopam 500mg Injection and Pramlintide when used together may enhance the effects of the other, which may increase the risk of side effects. .

How to manage the interaction:
Co-administration of Neopam 500mg Injection with Pramlintide is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

ANTIDOTES

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Neopam 500mg Injection contains Pralidoxime, a cholinesterase reactivator. It works by reactivating the enzyme cholinesterase (mainly outside the central nervous system), which has been inactivated by phosphorylation due to an organophosphate pesticide or related compounds and medicines.

Neopam 500mg Injection is an antidote Antidote for organophosphorus nerve agent poisoning, including chlorosarin, cyclosarin (GF), R-VX, tabun (GA), sarin (GB), VX, soman (GD), chlorosoman and organophosphorus pesticides.

Pralidoxime injection is also used to treat an overdose of medicines (such as neostigmine, ambenonium, and pyridostigmine) that treat myasthenia gravis.

Drug-Drug Interactions Checker List

  • MIVACURIUM
  • SUCCINYLCHOLINE

Disease/Condition Glossary

Organophosphorus poisoning occurs after dermal, respiratory, or oral exposure to pesticides or nerve agents. Poisoning can occur after short or long-term exposure. It can cause nerve damage and disrupt hormone production in humans and animals. Organophosphates are also toxic to plants and insects. Agricultural workers and others who handle agricultural chemicals may be at risk, with most exposure occurring in rural areas. 

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