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  1. Home
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  3. Nevrix-SR 75/1500 Tablet 10's

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Nevrix-SR 75/1500 Tablet 10's
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Written By ,
Reviewed By Sunny S , MBBS

Composition :

MECOBALAMIN-1500MCG+PREGABALIN-75MG

Manufacturer/Marketer :

Grivety Lifecare Llp

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

[ANTICONVULSANT]

Country of origin

India

Manufacturer/Marketer address

518, Saffron Business Park Nr. Jashodanagar Chokadi, Jashodanagar Ahmedabad Ahmedabad Gj 382445 In
Other Info - NEV0088

FAQs

Nevrix-SR 75/1500 Tablet 10's is a combination of two drugs: Pregabalin (antiepileptic) and Mecobalamin (vitamin B12). Pregabalin improves nerve signal conduction of damaged nerves. Methylcobalamin is a form of Vitamin B12 that helps in the regeneration of damaged nerves and helps produce the myelin sheath (outer protecting layer of nerves). Thus, Nevrix-SR 75/1500 Tablet 10's promotes healing of damaged nerve and improves nerve conduction in diabetes or traumatic conditions.

Dry mouth could be a side-effect of Nevrix-SR 75/1500 Tablet 10's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Nevrix-SR 75/1500 Tablet 10's may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.

Do not discontinue Nevrix-SR 75/1500 Tablet 10's without consulting your doctor as it could lead to withdrawal symptoms. To treat your condition effectually continue taking Nevrix-SR 75/1500 Tablet 10's for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Nevrix-SR 75/1500 Tablet 10's; your doctor will reduce the dose gradually.

Nevrix-SR 75/1500 Tablet 10's is used to treat neuropathic pain due to diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in the legs and feet.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Safe if prescribed

Avoid consumption of alcohol while taking Nevrix-SR 75/1500 Tablet 10's as it may increase drowsiness and sleepiness.

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Pregnancy

Consult your doctor

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor before taking Nevrix-SR 75/1500 Tablet 10's; your doctor will decide whether Nevrix-SR 75/1500 Tablet 10's can be taken by breastfeeding mothers or not.

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Driving

Safe if prescribed

Nevrix-SR 75/1500 Tablet 10's causes drowsiness, sleepiness, and blurred vision. Do not drive or operate machinery unless you are alert.

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Liver

Consult your doctor

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Nevrix-SR 75/1500 Tablet 10's should not be given to children as the safety and efficacy have not been established.

Product Substitutes

Reference

  1. https://www.drugs.com/mtm/methylcobalamin-vitamin-b12.html
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759374/
  3. https://www.nhs.uk/medicines/pregabalin/

About Nevrix-SR 75/1500 Tablet 10's

Nevrix-SR 75/1500 Tablet 10's belongs to a group of medications known as 'anticonvulsants' used to manage neuropathic pain due to damaged nerves. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling, or burning sensation. 

Nevrix-SR 75/1500 Tablet 10's is a combination of two drugs: Methylcobalamin/Mecobalamin (vitamin B12) and Pregabalin (anti-convulsant). Mecobalamin protects nerve fibres and rejuvenates nerve cells by producing a substance called myelin. Pregabalin works by changing how nerves send messages to the brain. Together, Nevrix-SR 75/1500 Tablet 10's helps to treat neuropathic pain (pain due to nerve damage). 

Take Nevrix-SR 75/1500 Tablet 10's as prescribed by your doctor. Depending on your medical condition, you are advised to take Nevrix-SR 75/1500 Tablet 10's for as long as your doctor has prescribed it for you. In some cases, you may experience common side effects such as nausea, vomiting, stomach pain, diarrhoea, loss of appetite, heartburn, dry mouth, dizziness, sleepiness, and uncoordinated body movements. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Nevrix-SR 75/1500 Tablet 10's if you are pregnant or breastfeeding unless prescribed by the doctor. Nevrix-SR 75/1500 Tablet 10's causes drowsiness and dizziness, so drive only if you are alert. Nevrix-SR 75/1500 Tablet 10's should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol with Nevrix-SR 75/1500 Tablet 10's as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects. Let your doctor know if you have a history of heart disease, severe kidney disease, disorders of the stomach or gut/bowel, and diabetes before using the Nevrix-SR 75/1500 Tablet 10's. 

Uses of Nevrix-SR 75/1500 Tablet 10's

Neuropathic pain

Medicinal Benefits Mweb

Key Benefits

Nevrix-SR 75/1500 Tablet 10's is a combination of two drugs: Mecobalamin and Pregabalin. Mecobalamin is used to restore vitamin B12 in the body to treat damaged nerve conditions due to diabetes or other traumatic situations. It also has a neuroprotective activity that helps the nerve cells to function properly and treat neuropathic pain. On the other side, Pregabalin prevents neuropathic pain (pain due to damaged nerves), fibromyalgia (musculoskeletal pain), and epilepsy (fits). It works by calming the damaged or overactive nerves in your body that may cause pain or seizures, thereby decreasing the number of pain signals sent out by damaged nerves in the body. Overall it reduces the pain which has been damaged or irritated due to conditions like chronic conditions, diabetes, trauma or epilepsy. Together, Nevrix-SR 75/1500 Tablet 10's helps to treat neuropathic pain.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Nevrix-SR 75/1500 Tablet 10's

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhea
  • Heartburn
  • Dryness in mouth
  • Dizziness
  • Blurred vision

Drug Warnings

Please do not stop taking Nevrix-SR 75/1500 Tablet 10's without consulting your doctor as it could cause withdrawal symptoms. Women of child-bearing potential should use effective contraception.  Inform your doctor before taking Nevrix-SR 75/1500 Tablet 10's if you have heart problems, bipolar syndrome, severe liver disease or porphyria, diabetes, and asthma. Please do not stop taking Nevrix-SR 75/1500 Tablet 10's without consulting your doctor as it could cause withdrawal symptoms. Avoid consuming alcohol along with Nevrix-SR 75/1500 Tablet 10's as it could lead to increased drowsiness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies such as killing or harming yourself. Nevrix-SR 75/1500 Tablet 10's contains Pregabalin, which can decrease sperm count and may affect fertility in men. Do not exceed the prescribed dose or duration of treatment. 

Drug-Drug Interactions

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PregabalinCodeine
Severe
PregabalinTapentadol
Severe

Drug-Drug Interactions

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PregabalinCodeine
Severe
How does the drug interact with Nevrix-SR 75/1500 Tablet:
Using Nevrix-SR 75/1500 Tablet together with Codeine may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Codeine and Nevrix-SR 75/1500 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinTapentadol
Severe
How does the drug interact with Nevrix-SR 75/1500 Tablet:
Using Tapentadol together with Nevrix-SR 75/1500 Tablet may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Nevrix-SR 75/1500 Tablet with Tapentadol can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not exceed the doses or frequency and duration of use advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinButorphanol
Severe
How does the drug interact with Nevrix-SR 75/1500 Tablet:
Using Nevrix-SR 75/1500 Tablet together with Butorphanol causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Butorphanol and Nevrix-SR 75/1500 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinRemifentanil
Severe
How does the drug interact with Nevrix-SR 75/1500 Tablet:
Using Nevrix-SR 75/1500 Tablet together with Remifentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking remifentanil and Nevrix-SR 75/1500 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinOxycodone
Severe
How does the drug interact with Nevrix-SR 75/1500 Tablet:
Using Nevrix-SR 75/1500 Tablet together with Oxycodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking oxycodone and Nevrix-SR 75/1500 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinHydromorphone
Severe
How does the drug interact with Nevrix-SR 75/1500 Tablet:
Using Nevrix-SR 75/1500 Tablet together with Hydromorphone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydromorphone and Nevrix-SR 75/1500 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinSodium oxybate
Severe
How does the drug interact with Nevrix-SR 75/1500 Tablet:
Using Sodium oxybate together with Nevrix-SR 75/1500 Tablet may increase the risk of side effects.

How to manage the interaction:
Although taking Nevrix-SR 75/1500 Tablet with Sodium oxybate together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience drowsiness, dizziness, lightheadedness, confusion, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination, consult the doctor. For at least six hours after taking sodium oxybate, avoid operating machinery or engaging in potentially dangerous activities. Also, be careful when getting up from a sitting or lying down posture. Do not stop using any medications without talking to a doctor.
PregabalinFentanyl
Severe
How does the drug interact with Nevrix-SR 75/1500 Tablet:
Using Nevrix-SR 75/1500 Tablet together with Fentanyl can increase the risk of side effects.

How to manage the interaction:
Although taking fentanyl together with Nevrix-SR 75/1500 Tablet can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you have dizziness, sleepiness, difficulty concentrating, or impairment in judgment. Do not stop taking any medication without consulting a doctor.
PregabalinHydrocodone
Severe
How does the drug interact with Nevrix-SR 75/1500 Tablet:
Using Nevrix-SR 75/1500 Tablet together with Hydrocodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydrocodone and Nevrix-SR 75/1500 Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinMethadone
Severe
How does the drug interact with Nevrix-SR 75/1500 Tablet:
Using Nevrix-SR 75/1500 Tablet together with Methadone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking methadone and Nevrix-SR 75/1500 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Habit Forming

No

Special Advise

  • Nevrix-SR 75/1500 Tablet 10's can make you feel dizzy or drowsy, try to get up slowly while rising from a sitting or lying position.
  • Nevrix-SR 75/1500 Tablet 10's can cause dry mouth, so in that case, you can drink water or fluids, suck hard candy or ice, chew (sugarless) gum, or use a saliva substitute.

Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain.
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

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