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  1. Home
  2. Medicine

  3. Nex 400mcg/1ml Injection

Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Santoshini Reddy G , M Pharmacy
48 Hrs returnable
Know More
COD available

Online payment accepted

Nex 400mcg/1ml Injection, Pack of 1 Injection
Nex 400mcg/1ml Injection, Pack of 1 Injection
Nex 400mcg/1ml Injection, Pack of 1 Injection
Nex 400mcg/1ml Injection, Pack of 1 Injection
Nex 400mcg/1ml Injection, Pack of 1 Injection
Nex 400mcg/1ml Injection, Pack of 1 Injection
Not for online sale
rxMedicinePrescription drug

Whats That

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Composition :

NALOXONE-400MCG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

OPIOID ANTAGONISTS

Country of origin

INDIA

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - NEX0046

Author Details

Lakshmithulasi YarraguntaDoctor badge

Written By

Lakshmithulasi Yarragunta

Pharm-D (PB)

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Aug 20, 2024 | 1:18 PM IST

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FAQs

Nex 400mcg/1ml Injection contains Naloxone, which works by inhibiting the effect of opioid receptors and thereby blocks the effects of opioids.

No, Nex 400mcg/1ml Injection should not be used with an opioid analgesic, as it may cause serious adverse effects of the drug. If you have any concerns, please discuss them with your doctor.

Inform your doctor about your medical conditions, allergic reactions, and medications you are already taking (especially opioid analgesics). Also, let your doctor know if you are pregnant, planning to become pregnant, or breastfeeding.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Consumption of alcohol is not recommended during treatment with this medicine as it can worsen the condition of the patient.

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Pregnancy

Caution

Nex 400mcg/1ml Injection should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. If administered during pregnancy, the doctor may need to monitor your unborn baby carefully after you receive the medication.

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Breast Feeding

Caution

Consult the doctor if you are breastfeeding. Caution should be exercised while using Nex 400mcg/1ml Injection in nursing mother.

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Driving

Not applicable

Nex 400mcg/1ml Injection will be administered in the hospital setting.

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Liver

Caution

Nex 400mcg/1ml Injection should be used with caution in patients with liver disease. So, inform your doctor if you have liver impairment. Regular monitoring of liver function tests is advisable while on treatment with this medicine.

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Kidney

Caution

Caution is recommended while administering Nex 400mcg/1ml Injection to patients with renal impairment. So, inform your doctor if you have kidney impairment. Your doctor will weigh the benefits and potential risks before prescribing Nex 400mcg/1ml Injection.

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Children

Caution

Nex 400mcg/1ml Injection should be used in children only if advised by the doctor.

Product Substitutes

Reference

  1. https://medlineplus.gov/druginfo/meds/a612022.html
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/215457s000lbl.pdf
  3. https://www.drugs.com/naloxone.html
  4. https://adf.org.au/drug-facts/naloxone/
  5. https://reference.medscape.com/drug/zimhi-naloxone-343741

About Nex 400mcg/1ml Injection

Nex 400mcg/1ml Injection is an opioid antagonist used to treat opioid overdose. This medicine is given as an emergency treatment where the use of high-potency opioids as a chemical weapon is suspected and as temporary prophylaxis of respiratory and/or central nervous system depression in military personnel and chemical incident responders.

Nex 400mcg/1ml Injection contains Naloxone, which belongs to the class of opioid receptor antagonists. It works by blocking the effect of opioid receptors and blocks the effects. Thereby it helps treat opioid overdose.

Nex 400mcg/1ml Injection may cause certain side effects such as nausea, vomiting, injection site reactions, dizziness, and headache.  If Nex 400mcg/1ml Injection causes any serious discomfort, speak with a doctor. Nex 400mcg/1ml Injection will be administered by the physician in an emergency.

Nex 400mcg/1ml Injection is generally given on an emergency basis. The patient's caregiver should inform the doctor about his/her previous medical and medication history beforehand. Also, inform the doctor if the patient is pregnant, planning to become pregnant, or breastfeeding.

Uses of Nex 400mcg/1ml Injection

Opioid overdose.

Medicinal Benefits Mweb

Medicinal Benefits

Nex 400mcg/1ml Injection contains Naloxone, which belongs to the class of medications called 'opioid-antagonist' used to treat opioid dependence. It works by blocking the effect of opioid receptors and thereby blocks the effects of opioids. It is used along with counselling and social support to help patients dependent on opioid drugs. This medicine is also used after surgery to reverse the effects of opiates given during surgery.

Directions for Use

Nex 400mcg/1ml Injection will be administered by a trained healthcare professional under emergency basis.

Side Effects of Nex 400mcg/1ml Injection

  • Injection site reactions (pain, burning or redness)
  • Hot flushes
  • Syncope (loss of consciousness)
  • Dizziness
  • Headache

Drug Warnings

Nex 400mcg/1ml Injection is generally given on an emergency basis. The patient's caregiver should inform the doctor about his/her previous medical and medication history beforehand. Also, let the doctor know if the patient is pregnant, planning to become pregnant, or breastfeeding.  Inform your doctor if you have increased blood pressure, liver/kidney disease, or are taking any medications before receiving Nex 400mcg/1ml Injection. Do not use other medications without the doctor's notice, especially opioid-containing ones. It may cause precipitation of severe opioid withdrawal and risk of recurrent respiratory and central nervous system depression. Hence, the patient should be monitored carefully after administration of Nex 400mcg/1ml Injection.

Drug-Drug Interactions

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NaloxoneNaloxegol
Severe
NaloxoneDroperidol
Severe

Drug-Drug Interactions

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NaloxoneNaloxegol
Severe
How does the drug interact with Nex 400mcg/1ml Injection:
Coadministration of Nex 400mcg/1ml Injection and Naloxegol can enhance the risk of opioid withdrawal (a response to a sudden lack of opioids in the body).

How to manage the interaction:
Although taking Nex 400mcg/1ml Injection and Naloxegol together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms like sweating, tearing, runny nose, chills, diarrhea, stomach pain, nausea, vomiting, anxiety, insomnia, irritability, or restlessness, it's important to call your doctor right away. Do not stop using any medications without talking to a doctor.
NaloxoneDroperidol
Severe
How does the drug interact with Nex 400mcg/1ml Injection:
Coadministration of Nex 400mcg/1ml Injection and Droperidol can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Nex 400mcg/1ml Injection and Droperidol together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience weakness, tiredness, drowsiness, chest pain or discomfort, confusion, muscle pain, cramps, dizziness, nausea, or vomiting consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CODEINE
  • HYDROCODONE
  • DROPERIDOL

Habit Forming

No

Special Advise

  • It is recommended to monitor liver function tests regularly.
  • Strictly warn patients against the use of opioids while on treatment with Nex 400mcg/1ml Injection.
  • Monitor for injection-site reactions.

Diet & Lifestyle Advise

  • Eat foods high in carbohydrates, especially the complex carbohydrates present in starchy food items like legumes (e.g., beans, lentils and peas), root vegetables (e.g., potatoes and carrots), pasta and bread, along with protein in meals.
  • A patient should consume supplements and vitamins as per their doctor's recommendation.
  • The patient should change his drinking priorities and prefer drinks like apple cider, vanilla shake, juice or lemonade with sparkling water, etc.
  • Get physical activity and enough rest.
  • Reduce caffeine and stop smoking, if possible.

Nex 400mcg/1ml Injection Substitute

Always consult your doctor before taking any new medications and supplements

  • Nalox Injection 1ml

    by Others

    ₹91.10per tablet
    ›

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