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Reviewed By Sunny S , MBBS
48 Hrs returnable
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Composition :

ESOMEPRAZOLE-40MG

Manufacturer/Marketer :

Gallberry Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTACIDS

Country of origin

India

Manufacturer/Marketer address

301/302, 3rd Floor, Saket Callipolis Sarjapur Main Road, Doddakannelli Bangalore, Karnataka 560035, India
Other Info - NEX0370

FAQs

Nexodec-40 Tablet 1 is a proton pump inhibitor (PPI), which is a type of medication. Proton pumps are enzymes found in the stomach lining that aid in the production of acid needed for digestion. Esomeprazole impairs the function of proton pumps. This decreases the quantity of acid produced by the stomach.

Prolonged intake of Nexodec-40 Tablet 1 may lead to atrophic gastritis (inflammation of stomach cells), Vitamin B12 deficiency and weakening of bones or osteoporosis (loss of calcium, magnesium and vitamin D). Your doctor may prescribe calcium, vitamin D or haemoglobin enhancing medications to cope with long term side effects.

No. Nexodec-40 Tablet 1 prevents excess production of stomach acid causing acid reflux and heartburn. If blood is coming in your stool or mucous immediately contact the doctor.

Yes. Nexodec-40 Tablet 1 can alter certain medical tests like neuroendocrine tumours (secretin stimulation test), and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such diagnostics test contact your doctor.

It is very unlikely that taking one or two extra doses by accident will cause any problems. However, you should check with your doctor if you have taken too much and have are feeling sweaty, have a fast heartbeat, are feeling sleepy.

There's no firm evidence to suggest that taking Nexodec-40 Tablet 1 will reduce fertility in either men or women. However, speak to your doctor if you're trying to get pregnant and do as advised.

You can eat and drink normally while taking Nexodec-40 Tablet 1. However, you should avoid foods that seem to make your indigestion worse, such as rich, spicy and fatty foods. You should also cut down on caffeinated drinks, such as tea, coffee and cola, as well as alcohol.

No. Gas and acidity are two different common discomforts. Acidity is caused when improper functioning of the valve (sphincter) is located at the junction of the stomach and food pipe. As a result stomach acid backflows and enters the upper part of the food pipe causing heartburn. On the other hand, gas is the result of the digestion of the food and drinks eliminating gases like carbon dioxide, hydrogen, nitrogen, methane, etc. from the body.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Drinking alcohol with Nexodec-40 Tablet 1 may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So try to avoid, limit alcohol or contact doctor before intake of Nexodec-40 Tablet 1.

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Pregnancy

Caution

Nexodec-40 Tablet 1 isn't usually recommended during pregnancy as there's no firm evidence it's safe. So, contact a doctor before intake of Nexodec-40 Tablet 1. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Caution

Nexodec-40 Tablet 1 passes into the breast milk. However, no evidence of risk has been reported. Please consult your doctor before intake of Nexodec-40 Tablet 1. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Driving

Caution

In some cases, Nexodec-40 Tablet 1 may cause dizziness, sleepy, or blur vision. If you observe these symptoms do not drive or operate heavy machinery until you feel better.

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Liver

Caution

Nexodec-40 Tablet 1 should be taken with precaution in patients with liver disease.

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Kidney

Caution

Patients with kidney disease should consult a doctor before taking Nexodec-40 Tablet 1.

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Children

Caution

Nexodec-40 Tablet 1 should not be prescribed for children under 5 years of age. Nexodec-40 Tablet 1 is generally prescribed from 5-16 years of children for the treatment of acid-related damage of the food pipe (erosive esophagitis).

About Nexodec-40 Tablet 1

Nexodec-40 Tablet 1 belongs to the class of drugs known as Proton pump inhibitor which reduces the amount of acid your stomach makes. It treats gastroesophageal reflux disease (GERD), stomach ulcers and Zollinger Ellison syndrome (overproduction of acid due to pancreatic tumour).

Nexodec-40 Tablet 1 helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum. Nexodec-40 Tablet 1 prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn.

Take Nexodec-40 Tablet 1 1-2hours prior food. You are advised to take Nexodec-40 Tablet 1 for as long as your doctor has prescribed it for you depending on your medical condition. An adult taking Nexodec-40 Tablet 1 might have common side effects like headache, diarrhoea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia (joint pain). In the case of children taking Nexodec-40 Tablet 1 might report upper respiratory tract infections (URI), headache, fever, diarrhoea, vomiting, rash, and abdominal pain.  These side effects are temporary and may get resolve after some time however if this side persists contact the doctor.

Nexodec-40 Tablet 1 is safe for pregnant and breastfeeding mothers but should be taken only after consulting a doctor. Tell your doctor if you have stomach or intestinal cancer, liver problem, allergic to Nexodec-40 Tablet 1, or will have an endoscopy in the future. Prolonged intake of Nexodec-40 Tablet 1 may cause deficiency of Vitamin B12 and low level of calcium, magnesium, and Vitamin D leading to osteoporosis.

Uses of Nexodec-40 Tablet 1

Hyperacidity, Heartburn, Stomach ulcer, Zollinger-Ellison syndrome

Medicinal Benefits Mweb

Medicinal Benefits

Nexodec-40 Tablet 1 is effective at healing erosive esophagitis (inflammation of food pipe), relieving symptoms of gastroesophageal reflux disease (heartburn), and Zollinger-Ellison syndrome. Nexodec-40 Tablet 1 works by irreversibly blocking the proton pump gate (which secretes stomach acid). It can be prescribed to all age groups including special populations like the elderly, pregnant, lactating mothers, kidney, and liver disease patients. Usually, no dosage adjustment is required for these groups.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.Suspension/Syrup: Shake the bottle well before use. Check the label for directions and take Nexodec-40 Tablet 1 in doses as prescribed by your doctor with the help of a measuring cup.Powder/granules: Check the label for directions before use. Mix the powder/granules in water, mix well and drink immediately.

Side Effects of Nexodec-40 Tablet 1

In adults

  • Headache
  • Diarrhoea
  • Nausea
  • Abdominal pain
  • Vomiting
  • Flatulence
  • Dizziness
  • Arthralgia (joint pain)

 

In Children

  • Upper respiratory tract infections (URI)
  • Headache
  • Fever
  • Diarrhoea
  • Vomiting
  • Rash
  • Abdominal pain

Drug Warnings

You should avoid taking Nexodec-40 Tablet 1 if you are allergic to Nexodec-40 Tablet 1 or proton pump inhibitors, have gastric cancer, liver disease, low magnesium level (osteoporosis), low vitamin B12, pregnant or planning for pregnancy, and breastfeeding mothers. Nexodec-40 Tablet 1 may interact with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, ampicillin antibiotic, anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines. Prolonged intake of Nexodec-40 Tablet 1 may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), Vitamin B12, and magnesium deficiency. Intake of Nexodec-40 Tablet 1 may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in mucous or stool) immediately consult the doctor. 

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
EsomeprazoleTacrolimus
Severe

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
How does the drug interact with Nexodec-40 Tablet 10's :
Nexodec-40 Tablet 10's may reduce rilpivirine absorption and blood levels, making the medicine less effective against HIV.

How to manage the interaction:
Although taking Nexodec-40 Tablet 10's with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if your symptoms do not improve. Do not discontinue using any medications without consulting a doctor.
EsomeprazoleTacrolimus
Severe
How does the drug interact with Nexodec-40 Tablet 10's :
Taking tacrolimus with Nexodec-40 Tablet 10's may significantly increase the blood levels of tacrolimus, which can lead to an increased risk of side effects.

How to manage the interaction:
Although taking Nexodec-40 Tablet 10's with Tacrolimus can result in an interaction, they can be taken together if prescribed by your doctor. However, contact a doctor immediately if you experience irregular heartbeat, blurring of vision, fever, chills, or muscle spasms. Do not discontinue any medications without consulting a doctor.
EsomeprazoleDacomitinib
Severe
How does the drug interact with Nexodec-40 Tablet 10's :
Nexodec-40 Tablet 10's can make Dacomitinib less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of Nexodec-40 Tablet 10's with Dacomitinib can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleGefitinib
Severe
How does the drug interact with Nexodec-40 Tablet 10's :
Taking gefitinib with Nexodec-40 Tablet 10's may reduce the effectiveness of gefitinib.

How to manage the interaction:
Although taking Nexodec-40 Tablet 10's and Gefitinib together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Gefitionib 12 hours before or after taking Nexodec-40 Tablet 10's . Do not stop taking any medications without consulting a doctor.
EsomeprazoleErlotinib
Severe
How does the drug interact with Nexodec-40 Tablet 10's :
Coadministration of erlotinib and Nexodec-40 Tablet 10's can reduce effects of erlotinib.

How to manage the interaction:
Taking Erlotinib and Nexodec-40 Tablet 10's together is generally avoided as it can possibly result in an interaction. It can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
EsomeprazoleDasatinib
Severe
How does the drug interact with Nexodec-40 Tablet 10's :
Using Dasatinib together with Nexodec-40 Tablet 10's may decrease the levels of Dasatinib.

How to manage the interaction:
Although taking Nexodec-40 Tablet 10's together with Dasatinib can result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
EsomeprazoleNelfinavir
Severe
How does the drug interact with Nexodec-40 Tablet 10's :
Taking nelfinavir with Nexodec-40 Tablet 10's may decrease the effects of nelfinavir.

How to manage the interaction:
Although taking Nexodec-40 Tablet 10's and Nelfinavir can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting your doctor.
EsomeprazoleCitalopram
Severe
How does the drug interact with Nexodec-40 Tablet 10's :
Combining Nexodec-40 Tablet 10's with Citalopram can increase the risk of irregular heart rhythm. .

How to manage the interaction:
Co-administration of Nexodec-40 Tablet 10's with Citalopram can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any symptoms like irregular heart rhythm, dizziness, fainting, or shortness of breath, it's important to contact your doctor immediately. Do not stop using any medications without a doctor's advice.
EsomeprazoleClopidogrel
Severe
How does the drug interact with Nexodec-40 Tablet 10's :
Coadministration of Clopidogrel with Nexodec-40 Tablet 10's may reduce the effectiveness of clopidogrel.

How to manage the interaction:
Taking clopidogrel and Nexodec-40 Tablet 10's together possibly has an interaction, but you can take these medications together if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleMethotrexate
Severe
How does the drug interact with Nexodec-40 Tablet 10's :
Co-administration of methotrexate and Nexodec-40 Tablet 10's can increase the blood levels and side effects of methotrexate.

How to manage the interaction:
Although taking Nexodec-40 Tablet 10's with Methotrexate can result in an interaction, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience headache, dizziness, nausea and vomiting. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CLOPIDOGREL
  • WARFARIN
  • KETOCONAZOLE
  • VORICONAZOLE
  • ITRACONAZOLE
  • POSACONAZOLE
  • ATAZANAVIR
  • NELFINAVIR
  • RILPIVIRINE
  • AMPICILLIN
  • RIFAMPICIN
  • DIGOXIN
  • METHOTREXATE

Habit Forming

No

Special Advise

Prolonged intake of Nexodec-40 Tablet 1 may be associated with increased risk of Clostridium difficile associated diarrhea, magnesium and Vitamin B-12 deficiency (increased risk of bone fracture), atrophic gastritis (inflammed lining of stomach), and acute interstitial nephritis (inflammed cells of kidney).

 

Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
  • Before going to sleep try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows, instead, one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid taking alcohol and smoking cigarette. Alcohol can raise the level of production of stomach acid leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter) which prevents backflow of the stomach acid back into the food pipe.
  • Include high fibre containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal. These foods are full of antioxidant, calcium and vitamin B 12 that can help cope with the long term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production. Cranberry juice can be beneficial in the peptic ulcer and H Pyroli infection.
  • Avoid regular sitting continuously, as it can increase stomach acid production. Try to take a break of 5 minutes in 1 hour by brisk walking or stretching.

Nexodec-40 Tablet 1 Substitute

Substitutes safety advice
  • Esomecare 40 Tablet 10's

    by Others

    10.70per tablet
  • Nexpro-40 Tablet 15's

    by Others

    11.37per tablet
  • Sompraz 40 Tablet 15's

    by Others

    10.80per tablet
  • Neksium 40 mg Tablet 15's

    by Others

    12.78per tablet
  • Nexpro Fast 40 Tablet 10's

    by Others

    14.72per tablet

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