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  3. Nitrol 20 mg Injection 10 ml

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

MITOXANTRONE-20MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

MISCELLANEOUS

Country of origin

India

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - NIT0222

FAQs

Nitrol 20 mg Injection contains Mitoxantrone. In Cancer treatment, Nitrol 20 mg Injection works by slowing down the growth of cancer cells.

In multiple sclerosis (MS) treatment, Nitrol 20 mg Injection works by slowing down an overactive immune system, which prevents or delays worsening symptoms. It also decreases the number of flare-ups.

Based on the medical condition, Nitrol 20 mg Injection may be given alone or together with other medicines used to treat Prostate cancer.

No, it is unsafe to father a child while taking Nitrol 20 mg Injection. Men using this Nitrol 20 mg Injection must use effective birth control whenever they have sex during their treatment and for a certain period after their final dose.

Nitrol 20 mg Injection can cause a significant decrease in the number of blood cells and platelets. Your doctor may suggest laboratory tests before and during the treatment. Tell your healthcare provider if you develop a fever or have signs of bruising or bleeding.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Avoid alcohol consumption while on treatment with Nitrol 20 mg Injection.

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Pregnancy

Unsafe

Nitrol 20 mg Injection should not be used during pregnancy as it may cause fetal harm. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.

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Breast Feeding

Unsafe

Nitrol 20 mg Injection may not be safe for use in breastfeeding. Your doctor may suggest you stop breastfeeding during the treatment and until a certain period after the last dose of Nitrol 20 mg Injection.

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Driving

Caution

Nitrol 20 mg Injection may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.

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Liver

Caution

Nitrol 20 mg Injection should not be used to treat patients with multiple sclerosis who have liver disease. Other patients with liver disease should be treated with caution, and their dosage may need to be adjusted.

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Kidney

Caution

Limited information was available about using Nitrol 20 mg Injection in patients with kidney disease. Inform your doctor before receiving the Nitrol 20 mg Injection if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

The safety and effectiveness of Nitrol 20 mg Injection in pediatric patients have not been established.

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Keep Refrigerated. Do not freeze.Prepaid payment required.

About Nitrol 20 mg Injection

Nitrol 20 mg Injection belongs to a group of medicines known as anthracenedioness. Nitrol 20 mg Injection treats leukaemia and prostate cancer. It may also be used to treat multiple sclerosis (MS). Leukaemia is a type of cancer that develops in blood-forming tissue. Prostate cancer is a type of cancer that only occurs in men and affects the prostate gland, a tiny gland under the bladder that produces semen. Multiple sclerosis is a condition that affects the brain and spinal cord, resulting in symptoms such as problems with sensation, balance, vision, pain, impaired coordination, and fatigue.

Nitrol 20 mg Injection contains Mitoxantrone. In Cancer treatment, Nitrol 20 mg Injection works by slowing down the growth of cancer cells. In multiple sclerosis (MS) treatment, Nitrol 20 mg Injection works by slowing down an overactive immune system, which prevents or delays worsening symptoms. It also decreases the number of flare-ups.

Nitrol 20 mg Injection should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents. Sometimes, you may experience common side effects, such as diarrhoea, hair loss, headache, irregular menstrual cycles or spotting, nausea, pain, redness, or swelling with sores inside the mouth or throat. Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.

Nitrol 20 mg Injection may cause fetal harm when administered to a pregnant woman. Women of childbearing potential should be advised to avoid becoming pregnant. Talk to your care team about reliable forms of contraception. A negative pregnancy test is required before starting this medication. Do not breastfeed while taking this medication. Men using this Nitrol 20 mg Injection must use effective birth control whenever they have sex during their treatment and for a certain period after their final dose.

Uses of Nitrol 20 mg Injection

Leukaemia, Prostate cancer and multiple sclerosis (MS)

Medicinal Benefits Mweb

Medicinal Benefits

Nitrol 20 mg Injection contains Mitoxantrone, which belongs to a group of medicines known as anthracenedioness. Nitrol 20 mg Injection is used to treat leukaemia and prostate cancer. It may also be useful in treating multiple sclerosis (MS). Nitrol 20 mg Injection helps in cancer treatment by decreasing the proliferation of cancer cells. Nitrol 20 mg Injection acts in treating multiple sclerosis (MS) by calming down an overactive immune system, which avoids or delays the worsening of symptoms. It also reduces the frequency of flare-ups.

Directions for Use

Nitrol 20 mg Injection should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents.

Side Effects of Nitrol 20 mg Injection

  • Nausea
  • Vomiting
  • increased infections
  • bruising and bleeding easily
  • Anemia 
  • Lower-than-normal levels of neutrophils
  • Low white blood cell count
  • Diarrhea
  • Tiredness
  • Nausea
  • Loss of appetite
  • Vomiting
  • Constipation
  • Abnormal weakness
  • Abdominal pain
  • Back pain
  • Peripheral neuropathy
  • Fever
  • Shortness of breath
  • Cough
  • Pain in joint
  • Hair loss

Drug Warnings

Before taking the Nitrol 20 mg Injection, let your doctor know about all your allergic or hypersensitivity reactions to medicines or food. White blood cells protect the body from infection. This medication may cause a decrease in the amount of white blood cells in your blood. You are more prone to catching an infection if your white blood cell count is low. When the quantity of white blood cells is too low, a condition can be deadly. It is critical to treat any infection as quickly as possible. Make an immediate call to the hospital. Use a condom or effective birth control method if you are having sex with pregnant women or women who can become pregnant. Mitoxantrone injection can produce severe or life-threatening allergic reactions, especially during the first induction course. If it happens, kindly inform your doctor immediately; your doctor may stop the second induction course, which should be withheld until the toxicity resolves. Mitoxantrone injection may cause cardiac damage at any moment during treatment or months to years after treatment has discontinued. This heart damage can be severe and fatal, and it can occur even in people who are not at risk for heart disease. Before starting mitoxantrone medication, your doctor will evaluate you and do certain tests to see how well your heart is operating and if you exhibit any indicators of cardiac problems.

Drug-Drug Interactions

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MitoxantroneBCG vaccine
Severe

Drug-Drug Interactions

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How does the drug interact with Nitrol 20 mg Injection 10 ml:
Taking thalidomide together with Nitrol 20 mg Injection 10 ml may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Nitrol 20 mg Injection 10 ml together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult a doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
MitoxantroneBCG vaccine
Severe
How does the drug interact with Nitrol 20 mg Injection 10 ml:
Using the BCG vaccine together with Nitrol 20 mg Injection 10 ml may increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Nitrol 20 mg Injection 10 ml and BCG vaccine, but it can be taken if prescribed by a doctor. However, consult a doctor immediately if you experience symptoms such as fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
How does the drug interact with Nitrol 20 mg Injection 10 ml:
Co-administration of Clozapine together with Nitrol 20 mg Injection 10 ml may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Nitrol 20 mg Injection 10 ml and Clozapine, you can take these medicines together if prescribed by a doctor. However, consult a doctor immediately if you experience symptoms such as fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
How does the drug interact with Nitrol 20 mg Injection 10 ml:
Using Nitrol 20 mg Injection 10 ml together with Deferiprone may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Nitrol 20 mg Injection 10 ml and Deferiprone, you can take these medicines together if prescribed by your doctor. However, consult a doctor immediately if you experience symptoms such as fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
MitoxantroneVoclosporin
Severe
How does the drug interact with Nitrol 20 mg Injection 10 ml:
Using voclosporin together with Nitrol 20 mg Injection 10 ml may increase the risk of serious infections.

How to manage the interaction:
Taking Nitrol 20 mg Injection 10 ml with Voclosporin together can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms like fever, chills, diarrhoea, sore throat, muscle aches, difficulty breathing, weight loss, or pain, make sure to contact your doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Nitrol 20 mg Injection 10 ml:
Taking leflunomide with Nitrol 20 mg Injection 10 ml may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Leflunomide with Nitrol 20 mg Injection 10 ml can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult a doctor immediately. Do not discontinue any medications without first consulting a doctor.
MitoxantroneDolasetron
Severe
How does the drug interact with Nitrol 20 mg Injection 10 ml:
Using dolasetron together with Nitrol 20 mg Injection 10 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Nitrol 20 mg Injection 10 ml and Dolasetron, you can take these medicines together if prescribed by your doctor. However, consult a doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting a doctor.
How does the drug interact with Nitrol 20 mg Injection 10 ml:
Using baricitinib together with Nitrol 20 mg Injection 10 ml may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Nitrol 20 mg Injection 10 ml with Baricitinib can result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
How does the drug interact with Nitrol 20 mg Injection 10 ml:
Using adalimumab together with Nitrol 20 mg Injection 10 ml may increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Nitrol 20 mg Injection 10 ml and Adalimumab, but it can be taken if prescribed by a doctor. However, if you experience symptoms like stomach pain, ongoing fever, excessive sweating at night, unexplained weight loss, infection, fever, chills, diarrhoea, a sore throat, muscle pain, difficulty breathing, or pain or discomfort when urinating. Do not discontinue any medications without first consulting a doctor.
How does the drug interact with Nitrol 20 mg Injection 10 ml:
Using fingolimod together with Nitrol 20 mg Injection 10 ml may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Nitrol 20 mg Injection 10 ml with Fingolimod can result in an interaction, but it can be taken if your doctor has advised it. However, consult a doctor immediately if you experience symptoms such as fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Drug-Drug Interactions Checker List

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  • SMALLPOX VACCINE
  • CLOZAPINE

Habit Forming

No

Special Advise

  • Nitrol 20 mg Injection should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Nitrol 20 mg Injection.
  • Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests to check your body's response to the Mitoxantrone injection.
  • Do not donate sperm during treatment with Nitrol 20 mg Injection for a certain period after your last dose.

Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs and added sugars.

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