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  3. Nitrol 20Mg\2Ml Inj

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Composition :

MITOXANTRONE-2MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

Parenteral

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

[MISCELLANEOUS]

Country of origin

India

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - NIT0191

FAQs

Nitrol 20Mg\2Ml Inj contains Mitoxantrone. In Cancer treatment, Nitrol 20Mg\2Ml Inj works by slowing down the growth of cancer cells.

In multiple sclerosis (MS) treatment, Nitrol 20Mg\2Ml Inj works by slowing down an overactive immune system, which prevents or delays worsening symptoms. It also decreases the number of flare-ups.

Based on the medical condition, Nitrol 20Mg\2Ml Inj may be given alone or together with other medicines used to treat Prostate cancer.

No, it is unsafe to father a child while taking Nitrol 20Mg\2Ml Inj. Men using this Nitrol 20Mg\2Ml Inj must use effective birth control whenever they have sex during their treatment and for a certain period after their final dose.

Nitrol 20Mg\2Ml Inj can cause a significant decrease in the number of blood cells and platelets. Your doctor may suggest laboratory tests before and during the treatment. Tell your healthcare provider if you develop a fever or have signs of bruising or bleeding.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Safe if prescribed

Avoid alcohol consumption while on treatment with Nitrol 20Mg\2Ml Inj.

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Pregnancy

Consult your doctor

Nitrol 20Mg\2Ml Inj should not be used during pregnancy as it may cause fetal harm. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.

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Breast Feeding

Consult your doctor

Nitrol 20Mg\2Ml Inj may not be safe for use in breastfeeding. Your doctor may suggest you stop breastfeeding during the treatment and until a certain period after the last dose of Nitrol 20Mg\2Ml Inj.

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Driving

Safe if prescribed

Nitrol 20Mg\2Ml Inj may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.

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Liver

Consult your doctor

Nitrol 20Mg\2Ml Inj should not be used to treat patients with multiple sclerosis who have liver disease. Other patients with liver disease should be treated with caution, and their dosage may need to be adjusted.

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Kidney

Consult your doctor

Limited information was available about using Nitrol 20Mg\2Ml Inj in patients with kidney disease. Inform your doctor before receiving the Nitrol 20Mg\2Ml Inj if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

The safety and effectiveness of Nitrol 20Mg\2Ml Inj in pediatric patients have not been established.

About Nitrol 20Mg\2Ml Inj

Nitrol 20Mg\2Ml Inj belongs to a group of medicines known as anthracenedioness. Nitrol 20Mg\2Ml Inj treats leukaemia and prostate cancer. It may also be used to treat multiple sclerosis (MS). Leukaemia is a type of cancer that develops in blood-forming tissue. Prostate cancer is a type of cancer that only occurs in men and affects the prostate gland, a tiny gland under the bladder that produces semen. Multiple sclerosis is a condition that affects the brain and spinal cord, resulting in symptoms such as problems with sensation, balance, vision, pain, impaired coordination, and fatigue.

Nitrol 20Mg\2Ml Inj contains Mitoxantrone. In Cancer treatment, Nitrol 20Mg\2Ml Inj works by slowing down the growth of cancer cells. In multiple sclerosis (MS) treatment, Nitrol 20Mg\2Ml Inj works by slowing down an overactive immune system, which prevents or delays worsening symptoms. It also decreases the number of flare-ups.

Nitrol 20Mg\2Ml Inj should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents. Sometimes, you may experience common side effects, such as diarrhoea, hair loss, headache, irregular menstrual cycles or spotting, nausea, pain, redness, or swelling with sores inside the mouth or throat. Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.

Nitrol 20Mg\2Ml Inj may cause fetal harm when administered to a pregnant woman. Women of childbearing potential should be advised to avoid becoming pregnant. Talk to your care team about reliable forms of contraception. A negative pregnancy test is required before starting this medication. Do not breastfeed while taking this medication. Men using this Nitrol 20Mg\2Ml Inj must use effective birth control whenever they have sex during their treatment and for a certain period after their final dose.

Uses of Nitrol 20Mg\2Ml Inj

Leukaemia, Prostate cancer and multiple sclerosis (MS)

Medicinal Benefits Mweb

Key Benefits

Nitrol 20Mg\2Ml Inj contains Mitoxantrone, which belongs to a group of medicines known as anthracenedioness. Nitrol 20Mg\2Ml Inj is used to treat leukaemia and prostate cancer. It may also be useful in treating multiple sclerosis (MS). Nitrol 20Mg\2Ml Inj helps in cancer treatment by decreasing the proliferation of cancer cells. Nitrol 20Mg\2Ml Inj acts in treating multiple sclerosis (MS) by calming down an overactive immune system, which avoids or delays the worsening of symptoms. It also reduces the frequency of flare-ups.

Directions for Use

Nitrol 20Mg\2Ml Inj should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents.

Side Effects of Nitrol 20Mg\2Ml Inj

  • Nausea
  • Vomiting
  • increased infections
  • bruising and bleeding easily
  • Anemia 
  • Lower-than-normal levels of neutrophils
  • Low white blood cell count
  • Diarrhea
  • Tiredness
  • Nausea
  • Loss of appetite
  • Vomiting
  • Constipation
  • Abnormal weakness
  • Abdominal pain
  • Back pain
  • Peripheral neuropathy
  • Fever
  • Shortness of breath
  • Cough
  • Pain in joint
  • Hair loss

Drug Warnings

Before taking the Nitrol 20Mg\2Ml Inj, let your doctor know about all your allergic or hypersensitivity reactions to medicines or food. White blood cells protect the body from infection. This medication may cause a decrease in the amount of white blood cells in your blood. You are more prone to catching an infection if your white blood cell count is low. When the quantity of white blood cells is too low, a condition can be deadly. It is critical to treat any infection as quickly as possible. Make an immediate call to the hospital. Use a condom or effective birth control method if you are having sex with pregnant women or women who can become pregnant. Mitoxantrone injection can produce severe or life-threatening allergic reactions, especially during the first induction course. If it happens, kindly inform your doctor immediately; your doctor may stop the second induction course, which should be withheld until the toxicity resolves. Mitoxantrone injection may cause cardiac damage at any moment during treatment or months to years after treatment has discontinued. This heart damage can be severe and fatal, and it can occur even in people who are not at risk for heart disease. Before starting mitoxantrone medication, your doctor will evaluate you and do certain tests to see how well your heart is operating and if you exhibit any indicators of cardiac problems.

Drug-Drug Interactions

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MitoxantroneVoclosporin
Severe

Drug-Drug Interactions

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How does the drug interact with Nitrol 20Mg\2Ml Inj:
Using natalizumab together with Nitrol 20Mg2Ml Inj may increase the risk of serious infections.

How to manage the interaction:
Taking Nitrol 20Mg2Ml Inj with Natalizumab together can result in an interaction, but it can be taken if your doctor has advised it. However, consult a doctor immediately if you experience symptoms such as fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
MitoxantroneVoclosporin
Severe
How does the drug interact with Nitrol 20Mg\2Ml Inj:
Using voclosporin together with Nitrol 20Mg2Ml Inj may increase the risk of serious infections.

How to manage the interaction:
Taking Nitrol 20Mg2Ml Inj with Voclosporin together can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms like fever, chills, diarrhoea, sore throat, muscle aches, difficulty breathing, weight loss, or pain, make sure to contact your doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Nitrol 20Mg\2Ml Inj:
Using fingolimod together with Nitrol 20Mg2Ml Inj may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Nitrol 20Mg2Ml Inj with Fingolimod can result in an interaction, but it can be taken if your doctor has advised it. However, consult a doctor immediately if you experience symptoms such as fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
How does the drug interact with Nitrol 20Mg\2Ml Inj:
Using adalimumab together with Nitrol 20Mg2Ml Inj may increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Nitrol 20Mg2Ml Inj and Adalimumab, but it can be taken if prescribed by a doctor. However, if you experience symptoms like stomach pain, ongoing fever, excessive sweating at night, unexplained weight loss, infection, fever, chills, diarrhoea, a sore throat, muscle pain, difficulty breathing, or pain or discomfort when urinating. Do not discontinue any medications without first consulting a doctor.
MitoxantroneTalimogene laherparepvec
Severe
How does the drug interact with Nitrol 20Mg\2Ml Inj:
Using Talimogene laherparepvec together with Nitrol 20Mg2Ml Inj may increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Nitrol 20Mg2Ml Inj and Talimogene laherparepvec, but it can be taken if prescribed by a doctor. Do not stop using any medications without consulting a doctor
How does the drug interact with Nitrol 20Mg\2Ml Inj:
Co-administration of Clozapine together with Nitrol 20Mg2Ml Inj may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Nitrol 20Mg2Ml Inj and Clozapine, you can take these medicines together if prescribed by a doctor. However, consult a doctor immediately if you experience symptoms such as fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
How does the drug interact with Nitrol 20Mg\2Ml Inj:
Using infliximab together with Nitrol 20Mg2Ml Inj may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Infliximab with Nitrol 20Mg2Ml Inj can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include a serious infection, sepsis, complications, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee. Do not stop using any medications without a doctor's advice.
How does the drug interact with Nitrol 20Mg\2Ml Inj:
Taking thalidomide together with Nitrol 20Mg2Ml Inj may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Nitrol 20Mg2Ml Inj together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult a doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nitrol 20Mg\2Ml Inj:
Taking leflunomide with Nitrol 20Mg2Ml Inj may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Leflunomide with Nitrol 20Mg2Ml Inj can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult a doctor immediately. Do not discontinue any medications without first consulting a doctor.
How does the drug interact with Nitrol 20Mg\2Ml Inj:
Using Nitrol 20Mg2Ml Inj together with Teriflunomide may increase the risk of serious infections.

How to manage the interaction:
Although taking Nitrol 20Mg2Ml Inj and Teriflunomide together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, sore throat, muscle aches, shortness of breath, weight loss, discomfort, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

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Habit Forming

No

Special Advise

  • Nitrol 20Mg\2Ml Inj should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Nitrol 20Mg\2Ml Inj.
  • Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests to check your body's response to the Mitoxantrone injection.
  • Do not donate sperm during treatment with Nitrol 20Mg\2Ml Inj for a certain period after your last dose.

Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs and added sugars.

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