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  3. Nizoclin 200 mg Tablet 10's

Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
48 Hrs returnable
Know More
COD available

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Nizoclin 200 mg Tablet 10's, Pack of 10 TABLETS
Nizoclin 200 mg Tablet 10's, Pack of 10 TABLETS
Nizoclin 200 mg Tablet 10's, Pack of 10 TABLETS
Nizoclin 200 mg Tablet 10's, Pack of 10 TABLETS
rxMedicinePrescription drug

Whats That

tooltip

Composition :

KETOCONAZOLE-200MG

Manufacturer/Marketer :

Canixa Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIFUNGALS - ORAL

Country of origin

India

Manufacturer/Marketer address

Lg Floor, Block No. 2, , Attalika Warehouse (South), , 12 Km Mysore Road, R.V.C.E. Post, , Bangalore 560059.
Other Info - NIZ0053

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Aug 20, 2024 | 1:14 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Nizoclin 200 mg Tablet works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Nizoclin 200 mg Tablet is not recommended to treat fungal meningitis (fungal infection spreads to the brain and spinal cord) as it poorly penetrates into the cerebrospinal fluid. Therefore, inform your doctor if you have fungal meningitis so that appropriate medication may be prescribed.

You are recommended to avoid foods containing chocolate and caffeine such as cocoa beans, tea, coffee, cola and energy drinks while taking Nizoclin 200 mg Tablet as it may increase the adverse effects of caffeine such as drowsiness, nervousness or nausea.

You are not recommended to take Nizoclin 200 mg Tablet with simvastatin (lipid-lowering drug) as co-administration of these medicines may cause muscle problems. Therefore, please consult a doctor before taking Nizoclin 200 mg Tablet with other medicines.

No, you are not recommended to stop taking Nizoclin 200 mg Tablet without consulting your doctor as it may cause recurring infection. Therefore, take Nizoclin 200 mg Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Nizoclin 200 mg Tablet , please consult your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Nizoclin 200 mg Tablet as it may increase the risk of liver damage and cause adverse effects.

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Pregnancy

Caution

Nizoclin 200 mg Tablet is a Category C pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Unsafe

Nizoclin 200 mg Tablet may be excreted in breast milk. Therefore, it is recommended to avoid breastfeeding while taking Nizoclin 200 mg Tablet .

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Driving

Caution

Nizoclin 200 mg Tablet may cause dizziness or drowsiness. Therefore, drive only if you alert after taking Nizoclin 200 mg Tablet .

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Liver

Unsafe

Nizoclin 200 mg Tablet is contraindicated in patients with chronic or acute liver disease. Therefore, inform your doctor if you have any Liver diseases/conditions.

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Kidney

Caution

If you have any concerns regarding the use of Nizoclin 200 mg Tablet in patients with kiver diseases/conditions, consult a doctor.

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Children

Caution

Nizoclin 200 mg Tablet is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that benefits outweigh risks.

Product Substitutes

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/018533s040lbl.pdf
  2. https://www.drugs.com/mtm/ketoconazole.html

About Nizoclin 200 mg Tablet

Nizoclin 200 mg Tablet belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus). It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks.

Nizoclin 200 mg Tablet contains Ketoconazole which works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Take Nizoclin 200 mg Tablet as prescribed. Your doctor will advise you on how often you need to take Nizoclin 200 mg Tablet based on your medical condition. Some people may experience headache, nausea, stomach pain, and diarrhoea. Most of these side effects of Nizoclin 200 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Nizoclin 200 mg Tablet . Avoid breastfeeding while taking Nizoclin 200 mg Tablet as it may be excreted in breast milk. You are recommended to avoid alcohol consumption whilst on treatment with Nizoclin 200 mg Tablet . Nizoclin 200 mg Tablet is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that the benefits outweigh the risks.

Uses of Nizoclin 200 mg Tablet

Systemic fungal infections

Medicinal Benefits Mweb

Medicinal Benefits

Nizoclin 200 mg Tablet is an antifungal used to treat severe fungal infections. It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks. It destroys fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Directions for Use

Take Nizoclin 200 mg Tablet with food to avoid stomach upset or take it as advised by the doctor. Swallow the whole tablet/capsule with a glass of water. Do not break, crush or chew it.

Side Effects of Nizoclin 200 mg Tablet

  • Headache
  • Nausea
  • Stomach pain
  • Diarrhoea 

Drug Warnings

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Nizoclin 200 mg Tablet . Avoid breastfeeding while taking Nizoclin 200 mg Tablet as it may be excreted in breast milk. You are recommended to avoid alcohol consumption with Nizoclin 200 mg Tablet . If you have a loss of appetite, tiredness, stomach pain, vomiting, yellowing of skin or eyes, dark urine, or light-coloured stools, inform your doctor immediately as they might be symptoms of hepatotoxicity (liver damage). 

Drug-Drug Interactions

verifiedApollotooltip
KetoconazoleHalofantrine
Critical
KetoconazoleConivaptan
Critical

Drug-Drug Interactions

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KetoconazoleHalofantrine
Critical
How does the drug interact with Nizoclin 200 mg Tablet:
Using Nizoclin 200 mg Tablet with Halofantrine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Nizoclin 200 mg Tablet with Halofantrine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
KetoconazoleConivaptan
Critical
How does the drug interact with Nizoclin 200 mg Tablet:
Using conivaptan together with Nizoclin 200 mg Tablet may significantly increase the blood levels of conivaptan, which may increase the risk of side effects.

How to manage the interaction:
Taking Nizoclin 200 mg Tablet with Conivaptan is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures(fits), consult the doctor immediately. Do not discontinue any medication without consulting a doctor.
KetoconazoleCisapride
Critical
How does the drug interact with Nizoclin 200 mg Tablet:
When Cisapride is taken with Nizoclin 200 mg Tablet, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Cisapride with Nizoclin 200 mg Tablet is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
KetoconazoleEliglustat
Critical
How does the drug interact with Nizoclin 200 mg Tablet:
When Eliglustat is taken with Nizoclin 200 mg Tablet, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Nizoclin 200 mg Tablet with Eliglustat is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or slow heart rate, weak pulse, or heart palpitations, consult the doctor immediately. Do not stop any medications without a doctor's advice.
KetoconazoleEplerenone
Critical
How does the drug interact with Nizoclin 200 mg Tablet:
Coadministration of Nizoclin 200 mg Tablet with Eplerenone can increase the levels of blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking Nizoclin 200 mg Tablet with Eplerenone is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without the doctor's advice.
KetoconazoleLovastatin
Critical
How does the drug interact with Nizoclin 200 mg Tablet:
Coadministration of Lovastatin with Nizoclin 200 mg Tablet can increase the risk of liver damage, rhabdomyolysis (the breakdown of skeletal muscle tissue) which may lead to kidney damage.

How to manage the interaction:
Taking Nizoclin 200 mg Tablet with Lovastatin is not recommended as it can cause an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms like unexplained muscular pain, tenderness, weakness, accompanied by fever, dark urine or unexpected bruising or bleeding, skin rash, itching, vomiting, yellowing of the skin or eyes, chills, joint pain, swelling, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
KetoconazoleDronedarone
Critical
How does the drug interact with Nizoclin 200 mg Tablet:
When Dronedarone is taken with Nizoclin 200 mg Tablet, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Nizoclin 200 mg Tablet with Dronedarone is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
KetoconazoleDisopyramide
Critical
How does the drug interact with Nizoclin 200 mg Tablet:
Taking Nizoclin 200 mg Tablet and Disopyramide together can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Nizoclin 200 mg Tablet with Disopyramide is not recommended as it can cause an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms like dizziness, irritation, confusion, chest pain or tightness, swelling, fatigue, palpitations, shortness of breath, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
KetoconazoleZiprasidone
Critical
How does the drug interact with Nizoclin 200 mg Tablet:
Taking Nizoclin 200 mg Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Nizoclin 200 mg Tablet is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, breathing difficult. Do not discontinue any medications without consulting a doctor.
KetoconazoleMethadone
Critical
How does the drug interact with Nizoclin 200 mg Tablet:
When Methadone is taken with Nizoclin 200 mg Tablet, it can increase the risk of serious side effects such as respiratory problems, low blood pressure, irregular heart rhythm.

How to manage the interaction:
Taking Nizoclin 200 mg Tablet with Methadone is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience breathing difficulty, fainting, heart palpitations, consult the doctor immediately. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of grapefruit or its juice with Nizoclin 200 mg Tablet may result in side effects such as joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, dark urine, light colored stools, and yellowing of the skin or eyes. Avoid consuming grapefruit, grapefruit juice, or any supplements that include grapefruit extract while taking Nizoclin 200 mg Tablet.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • QUINIDINE
  • DOFETILIDE
  • PIMOZIDE
  • OMEPRAZOLE
  • CISAPRIDE
  • SIMVASTATIN
  • LOVASTATIN
  • DIHYDROERGOTAMINE
  • ERGOTAMINE
  • NISOLDIPINE
  • EPLERENONE
  • ALPRAZOLAM
  • TRIAZOLAM
  • MIDAZOLAM

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid high-risk areas such as renovated buildings, construction sites, pigeon or chick coops, and caves.
  • Wear a respiratory mask when there is a risk of exposure to spores.
  • People with a weak immune system are advised to avoid activities that involve close contact with dust or dirt including digging, yard work, and gardening.
  • Close windows and stay inside during dust storms.
  • Clean skin injuries well with soap and water to reduce the risk of developing a skin infection.

Nizoclin 200 mg Tablet Substitute

Always consult your doctor before taking any new medications and supplements

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