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  1. Home
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  3. Nofsterone 5mg Tablet

Nofsterone 5mg Tablet, Pack of 1 Tablet
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Written By Veda Maddala , M Pharmacy
Reviewed By Sureshvarma D , MPharma
48 Hrs returnable
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COD available

Online payment accepted

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Whats That

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Composition :

NORETHISTERONE-5MG

Manufacturer/Marketer :

Cenofi Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

PROGESTIN

Country of origin

India
Other Info - NO37343

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Sureshvarma D

Reviewed By

Sureshvarma D

MPharma

Last Updated

Jul 8, 2025 | 9:39 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Nofsterone 5mg Tablet contains Norethisterone, a synthetic hormone that works by mimicking the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Nofsterone 5mg Tablet may be used to delay periods. Nofsterone 5mg Tablet keeps progesterone levels high and prevents shedding of the womb lining. However, please consult a doctor before using Nofsterone 5mg Tablet.

Nofsterone 5mg Tablet may increase the risk of a blood clot in the veins of the leg, especially if you are overweight, smoking, or have a history of a blood clot in the lungs or veins, repeated miscarriage or have major surgery, serious injury, or systemic lupus erythematosus (autoimmune disease). Therefore, please inform your doctor if you have any of these conditions before taking Nofsterone 5mg Tablet.

You are not recommended to take Nofsterone 5mg Tablet with rifampicin as it may decrease the levels of Nofsterone 5mg Tablet in blood and reduce its effectiveness. However, please consult a doctor before taking Nofsterone 5mg Tablet with other medicines.

Periods usually resume within 3 days of discontinuing Nofsterone 5mg Tablet. However, please consult a doctor if you have any concerns regarding this.

Nofsterone 5mg Tablet may cause changes in blood sugar levels. Therefore, it is advised to regularly monitor blood sugar levels while taking Nofsterone 5mg Tablet and inform your doctor if you have diabetes before taking Nofsterone 5mg Tablet.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

The interaction of Nofsterone 5mg Tablet with alcohol is unknown. Please consult a doctor before consuming alcohol while using Nofsterone 5mg Tablet.

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Pregnancy

Unsafe

Nofsterone 5mg Tablet is a category X pregnancy drug and is not recommended for use during pregnancy as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Nofsterone 5mg Tablet is given to breastfeeding women only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Safe if prescribed

Nofsterone 5mg Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Unsafe

Nofsterone 5mg Tablet is not recommended if you have liver disease. However, if you have any concerns regarding this, please consult a doctor.

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Kidney

Caution

Take Nofsterone 5mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Nofsterone 5mg Tablet is not recommended for use in children under 18 years.

Product Substitutes

Reference

  1. https://www.medicines.org.uk/emc/files/pil.1494.pdf
  2. https://www.drugs.com/mtm/norethindrone.html

About Nofsterone 5mg Tablet

Nofsterone 5mg Tablet belongs to the class of medicines called progestogens used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, Nofsterone 5mg Tablet may be used in the treatment of breast cancer. Endometriosis is a disorder in which the uterus's tissue lining (endometrium) grows on the ovaries, bowel, or tissues lining the pelvis. The most common symptom is pelvic pain.

Nofsterone 5mg Tablet contains Norethisterone that works by mimicking the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Take Nofsterone 5mg Tablet as prescribed by your doctor. You are advised to take Nofsterone 5mg Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, diarrhea, headache, breast pain, and tenderness. Most of these side effects of Nofsterone 5mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Nofsterone 5mg Tablet or any other medicines, please tell your doctor. Nofsterone 5mg Tablet is not recommended for pregnant women as it may harm the unborn baby. If you are breastfeeding, consult a doctor before taking Nofsterone 5mg Tablet. It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking Nofsterone 5mg Tablet. You are advised to stop smoking while taking Nofsterone 5mg Tablet as it may increase the risk of adverse effects.

Uses of Nofsterone 5mg Tablet

Heavy, painful or irregular periods, Premenstrual syndrome (PMS), Endometriosis, Breast cancer

Medicinal Benefits Mweb

Medicinal Benefits

Nofsterone 5mg Tablet contains Norethisterone, a synthetic hormone that mimics the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Directions for Use

Take Nofsterone 5mg Tablet with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Side Effects of Nofsterone 5mg Tablet

  • Unusual vaginal bleeding or spotting
  • Dizziness
  • Dry mouth
  • Constipation
  • Abdominal pain/cramps
  • Nausea
  • Diarrhea
  • Headache
  • Breast pain and tenderness

Drug Warnings

If you are allergic to Nofsterone 5mg Tablet or any other medicines, please tell your doctor. Nofsterone 5mg Tablet is not recommended for pregnant women as it may harm an unborn baby. If you are breastfeeding, consult a doctor before taking Nofsterone 5mg Tablet. It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking Nofsterone 5mg Tablet. You are advised to stop smoking while taking Nofsterone 5mg Tablet as it may increase the risk of adverse effects. If you are about to undergo any surgery, please inform your doctor that you are taking Nofsterone 5mg Tablet as it may increase the effect of certain anesthetics. If you experience sudden shortness of breath, rapid heartbeat, sudden, severe, sharp pain in the chest, or cough up blood, stop taking Nofsterone 5mg Tablet and consult a doctor immediately as these might be signs of a blood clot in the lungs.

Drug-Drug Interactions

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NorethisteroneGriseofulvin
Severe
NorethisteroneTopiramate
Severe

Drug-Drug Interactions

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NorethisteroneGriseofulvin
Severe
How does the drug interact with Nofsterone 5mg Tablet:
Taking griseofulvin with Nofsterone 5mg Tablet may reduce blood levels and the effects of Nofsterone 5mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Griseofulvin and Nofsterone 5mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any of these symptoms like unexpected bleeding or abnormal bleeding, it's important to contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneTopiramate
Severe
How does the drug interact with Nofsterone 5mg Tablet:
Coadministration of Nofsterone 5mg Tablet with Topiramate can reduce the blood levels and effects of norethindrone in the body. This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Taking Nofsterone 5mg Tablet and topiramate together can result in an interaction; it can be taken if your doctor has advised it. However, if you notice any symptoms of abnormal bleeding, hot flashes or vaginal dryness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NorethisteroneOxcarbazepine
Severe
How does the drug interact with Nofsterone 5mg Tablet:
Coadministration of Nofsterone 5mg Tablet with Oxcarbazepine can reduce the blood levels and effects of norethindrone. This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Although taking oxcarbazepine and Nofsterone 5mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience any symptoms like abnormal bleeding, consult the doctor immediately Do not discontinue any medications without consulting a doctor.
NorethisteroneTizanidine
Severe
How does the drug interact with Nofsterone 5mg Tablet:
Coadministration of Nofsterone 5mg Tablet with Tizanidine can cause drowsiness, confusion, slow heart rate, shallow breathing, feeling light-headed, fainting.

How to manage the interaction:
Taking Nofsterone 5mg Tablet with Tizanidine together can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NorethisteroneEslicarbazepine
Severe
How does the drug interact with Nofsterone 5mg Tablet:
Eslicarbazepine may reduce the effects of Nofsterone 5mg Tablet and its blood levels.

How to manage the interaction:
Although taking Eslicarbazepine and Nofsterone 5mg Tablet results in an interaction, they can be taken together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.
NorethisteroneEtretinate
Severe
How does the drug interact with Nofsterone 5mg Tablet:
Using Etretinate and Nofsterone 5mg Tablet together can cause severe, birth defects. Never use etretinate if you are pregnant. Both a primary and a secondary form of birth control must be used together and for at least 3 years after stopping therapy.

How to manage the interaction:
Although taking Nofsterone 5mg Tablet and Etretinate together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs, make sure to contact your doctor right away. These symptoms may be related to your birth control. Do not stop using any medications without a doctor's advice.
NorethisteroneBoceprevir
Severe
How does the drug interact with Nofsterone 5mg Tablet:
Using Boceprevir and Nofsterone 5mg Tablet together can reduce the blood levels and decrease the effectiveness of norethindrone.

How to manage the interaction:
Combining Boceprevir with Nofsterone 5mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, abnormal bleeding, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneBosentan
Severe
How does the drug interact with Nofsterone 5mg Tablet:
Co-administration of Nofsterone 5mg Tablet with Bosentan can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
Taking Nofsterone 5mg Tablet with Bosentan together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
NorethisteronePhenytoin
Severe
How does the drug interact with Nofsterone 5mg Tablet:
Coadministration of Phenytoin and Nofsterone 5mg Tablet may decrease the blood levels of Nofsterone 5mg Tablet, which may make Nofsterone 5mg Tablet less effective.

How to manage the interaction:
Although taking Phenytoin and Nofsterone 5mg Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. If you experience any symptoms, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
NorethisteroneFelbamate
Severe
How does the drug interact with Nofsterone 5mg Tablet:
Using Felbamate and Nofsterone 5mg Tablet together can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
There may be a possibility of interaction between Nofsterone 5mg Tablet and Felbamate, but it can be taken if prescribed by a doctor. If you notice any unusual symptoms like changes in your menstrual cycle, excessive bleeding, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice may increase the blood levels of Nofsterone 5mg Tablet. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Nofsterone 5mg Tablet dose. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Nofsterone 5mg Tablet dose.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • PHENYTOIN
  • NELFINAVIR
  • RITONAVIR
  • AMINOGLUTETHIMIDE
  • COTRIMOXAZOLE
  • RIFAMPICIN
  • TETRACYCLINE
  • CICLOSPORIN

Habit Forming

No

Special Advise

  • Nofsterone 5mg Tablet may interfere with certain laboratory tests. Therefore, inform your doctor that you are taking Nofsterone 5mg Tablet before undergoing any tests.

Diet & Lifestyle Advise

  • Avoid fried and processed foods.
  • Include fiber-rich foods like whole grains, fruits, and vegetables in your diet.
  • Avoid refined carbohydrates that are high in sugars.
  • Replace animal proteins (like eggs, fish, and meat) with vegetable protein sources (nuts, seeds, and beans).
  • Avoid drinking excess alcohol or caffeinated drinks as they can worsen the symptoms.
  • Maintain a healthy weight, do moderate exercise regularly.
  • Avoid smoking and alcohol intake.

Nofsterone 5mg Tablet Substitute

Substitutes safety advice

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