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Prescription drug
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Composition :

TOFACITINIB-1MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Medicinal Benefits Mweb

Medicinal Benefits

Novanib-T Oral Solution 100 ml belongs to a group of medicines called Janus kinase inhibitors used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Novanib-T Oral Solution 100 ml works by blocking Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis. Novanib-T Oral Solution 100 ml is indicated for patients with moderate to severe rheumatic arthritis, and psoriatic arthritis who have had intolerance or inadequate response to methotrexate or DMARDs (Disease-Modifying Anti-Rheumatic Drugs).

About Novanib-T Oral Solution 100 ml

Novanib-T Oral Solution 100 ml belongs to a group of medicines called Janus kinase inhibitors used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Psoriatic arthritis is an inflammatory condition of the joints, often associated with psoriasis. Ulcerative colitis is an inflammatory disease of the large intestine.
 
Novanib-T Oral Solution 100 ml contains 'Tofacitinib' which works by blocking the Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis. 
 
In some cases, you may experience common side-effects such as diarrhoea, headache, upper respiratory tract infection, cold, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Inform your doctor if you have an active infection, if you have a condition that increases the chance of having infections, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids. Avoid taking Novanib-T Oral Solution 100 ml if you are pregnant or breastfeeding. Novanib-T Oral Solution 100 ml is not recommended for children below 18 years as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Drug-Drug Interactions

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TofacitinibNelfinavir
Severe

Drug-Drug Interactions

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How does the drug interact with Novanib-T Oral Solution 100 ml:
Taking Novanib-T Oral Solution 100 ml with atazanavir may increase the blood levels of Novanib-T Oral Solution 100 ml. This may lead to cause severe infections.

How to manage the interaction:
Co-administration of Novanib-T Oral Solution 100 ml with Atazanavir can possibly result in an interaction, but it can be taken if your doctor has advised it. However consult your doctor if you experience fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to your doctor.
TofacitinibNelfinavir
Severe
How does the drug interact with Novanib-T Oral Solution 100 ml:
When Novanib-T Oral Solution 100 ml is taken with Nelfinavir, that may increase the risk of side effects.

How to manage the interaction:
Although taking Novanib-T Oral Solution 100 ml and Nelfinavir together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
TofacitinibAntithymocyte Globulin
Severe
How does the drug interact with Novanib-T Oral Solution 100 ml:
Using Novanib-T Oral Solution 100 ml together with antithymocyte globulin can increase the risk of serious infections.

How to manage the interaction:
Taking Antithymocyte Globulin with Novanib-T Oral Solution 100 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination contact your doctor. Do not discontinue any medications without consulting your doctor.
TofacitinibAbatacept
Severe
How does the drug interact with Novanib-T Oral Solution 100 ml:
Using Novanib-T Oral Solution 100 ml together with abatacept can increase the risk of serious infections.

How to manage the interaction:
Taking Abatacept with Novanib-T Oral Solution 100 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, sore throat, muscle aches, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Novanib-T Oral Solution 100 ml:
Coadministration of Ketoconazole and Novanib-T Oral Solution 100 ml may increase the blood levels and effects of Novanib-T Oral Solution 100 ml which may lead to side effects (low blood cell counts, anemia, serious infections, and elevated blood lipid levels).

How to manage the interaction:
Although taking Ketoconazole and Novanib-T Oral Solution 100 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms like paleness, exhaustion, dizziness, fainting, fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in the phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning when urinating, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Novanib-T Oral Solution 100 ml:
Using Novanib-T Oral Solution 100 ml together with bendamustine may increase the risk of developing serious infections.

How to manage the interaction:
Taking Novanib-T Oral Solution 100 ml with Bendamustine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Novanib-T Oral Solution 100 ml:
Taking Novanib-T Oral Solution 100 ml with Pemetrexed may increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Pemetrexed and Novanib-T Oral Solution 100 ml, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Novanib-T Oral Solution 100 ml:
Taking Imatinib and Novanib-T Oral Solution 100 ml can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, Imatinib can be taken with Novanib-T Oral Solution 100 ml if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Novanib-T Oral Solution 100 ml:
Taking Novanib-T Oral Solution 100 ml with phenobarbital, may decrease Novanib-T Oral Solution 100 ml blood levels and effects.

How to manage the interaction:
Although taking phenobarbital and Novanib-T Oral Solution 100 ml together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Novanib-T Oral Solution 100 ml:
Taking Novanib-T Oral Solution 100 ml with Temsirolimus may increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Novanib-T Oral Solution 100 ml and Temsirolimus, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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TOFACITINIB-1MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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TOFACITINIB-1MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice

How to manage the interaction:
Consuming grapefruit products while taking Novanib-T Oral Solution 100 ml can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Novanib-T Oral Solution 100 ml, as it can lead to an interaction.

Therapeutic Class

ANTIRHEUMATICS, DISEASE MODIFYING ANTIRHEUMATIC DRUGS (DMARDs)

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FAQs

Country of origin

India

Manufacturer/Marketer address

142 Ab, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra.
Other Info - NOV0590

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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