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Written By Divya L , PharmaD
Reviewed By Sureshvarma D , MPharma

Composition :

BUPIVACAINE-100MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

Other Info - NUM0042

Author Details

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About Numbcaine Heavy 20 Mg/4 Ml Inj

Uses of Numbcaine Heavy 20 Mg/4 Ml Inj

Medicinal Benefits Mweb

Key Benefits

Directions for Use

Side Effects of Numbcaine Heavy 20 Mg/4 Ml Inj

Drug Warnings

Drug-Drug Interactions

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BupivacaineEtidocaine
Severe

Drug-Drug Interactions

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BupivacaineEtidocaine
Severe
How does the drug interact with Numbcaine Heavy 20 Mg/4 Ml Inj:
Combining Numbcaine Heavy 20 Mg/4 Ml Inj with etidocaine can have additive toxic effects, so using them together increases the risk of serious side effects like methemoglobinemia (a condition that can deprive tissues and organs of oxygen), reactions in the central nervous system (e.g-convulsions, unconsciousness, coma, respiratory arrest), and cardiovascular disorders (e.g- low blood pressure, heart block, irregular heart rhythm).

How to manage the interaction:
Although there is a possible interaction between Etidocaine and Numbcaine Heavy 20 Mg/4 Ml Inj, you can take these medicines together if prescribed by your doctor. However, if you experience pale, grey, or blue-coloured skin, headache, rapid heart rate, shortness of breath, lightheadedness, or fatigue, consult a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Numbcaine Heavy 20 Mg/4 Ml Inj:
Taking Numbcaine Heavy 20 Mg/4 Ml Inj and Flutamide may cause methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Numbcaine Heavy 20 Mg/4 Ml Inj and Flutamide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Numbcaine Heavy 20 Mg/4 Ml Inj:
Taking Numbcaine Heavy 20 Mg/4 Ml Inj with rasburicase can increase the risk of methemoglobinemia(blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Taking Numbcaine Heavy 20 Mg/4 Ml Inj with Rasburicase together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacaineNitric oxide
Severe
How does the drug interact with Numbcaine Heavy 20 Mg/4 Ml Inj:
Taking Numbcaine Heavy 20 Mg/4 Ml Inj and Nitric oxide may cause methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Numbcaine Heavy 20 Mg/4 Ml Inj and nitric oxide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Numbcaine Heavy 20 Mg/4 Ml Inj:
Taking Numbcaine Heavy 20 Mg/4 Ml Inj with chloroquine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Numbcaine Heavy 20 Mg/4 Ml Inj and chloroquine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Numbcaine Heavy 20 Mg/4 Ml Inj:
Coadministration of Numbcaine Heavy 20 Mg/4 Ml Inj and sulfasalazine may result in methemoglobinemia, an uncommon disorder that lowers the blood's ability to carry oxygen, which can induce oxygen deprivation in tissues and essential organs.

How to manage the interaction:
Although taking Numbcaine Heavy 20 Mg/4 Ml Inj and sulfasalazine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as grey discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Numbcaine Heavy 20 Mg/4 Ml Inj:
Coadministration of Numbcaine Heavy 20 Mg/4 Ml Inj and Metoclopramide can increase the risk of methemoglobinemia (a condition in which the iron in the hemoglobin molecule (the red blood pigment) is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although there is a possible interaction between metoclopramide and Numbcaine Heavy 20 Mg/4 Ml Inj, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as grey discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Numbcaine Heavy 20 Mg/4 Ml Inj:
Taking Numbcaine Heavy 20 Mg/4 Ml Inj and Ifosfamide may cause methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Numbcaine Heavy 20 Mg/4 Ml Inj and ifosfamide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacaineMepivacaine
Severe
How does the drug interact with Numbcaine Heavy 20 Mg/4 Ml Inj:
Combining Numbcaine Heavy 20 Mg/4 Ml Inj with Mepivacaine can have additive toxic effects, so using them together increases the risk of serious side effects like methemoglobinemia (a condition that can deprive tissues and organs of oxygen), reactions in the central nervous system (e.g-convulsions, unconsciousness, coma, respiratory arrest), and cardiovascular disorders (e.g- low blood pressure, heart block, irregular heart rhythm).

How to manage the interaction:
Although taking Mepivacaine and Numbcaine Heavy 20 Mg/4 Ml Inj together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience pale, grey, or blue-coloured skin, headache, rapid heart rate, shortness of breath, lightheadedness, or fatigue, consult a doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Numbcaine Heavy 20 Mg/4 Ml Inj:
Taking Mexiletine with Numbcaine Heavy 20 Mg/4 Ml Inj may cause serious side effects including methemoglobinemia, a serious blood disorder in which too little oxygen is delivered to your cells and heart problems.

How to manage the interaction:
Although taking Numbcaine Heavy 20 Mg/4 Ml Inj and mexiletine together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately if you develop pale, grey, or blue-coloured skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, Jerking movements of the arms and legs, Loss of consciousness, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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