Nuroplus-D3 Tablet is a combination medication indicated for the management of neuropathic pain associated with diabetic neuropathy, post-herpetic neuralgia (damage to the nerve fibres during shingles infection), pain in fibromyalgia (musculoskeletal pain) or spinal cord injury. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. 

Nuroplus-D3 Tablet contains Pregabalin, Nortriptyline, Methylcobalamin, and Cholecalciferol. Pregabalin is an antiepileptic agent/anticonvulsant that affects the chemicals in the brain that send pain signals across the nervous system, thereby relieving nerve pain. Nortriptyline (antidepressant) works by increasing neurotransmitters (serotonin and noradrenaline) in the brain, thus reducing the pain signals in the brain. Mecobalamin/Methylcobalamin, a form of vitamin B12, regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Cholecalciferol/Vitamin D3 promotes a neuroprotective effect and prevents the progression of nerve damage.

Your doctor will decide the dosage based on your medical condition. Sometimes, Nuroplus-D3 Tablet may have common side effects like dizziness, drowsiness, blurred vision, shakiness, headache, nausea, vomiting, constipation, weight gain, swelling in the hands and feet, and dry mouth. These side effects do not require medical attention and gradually resolve over time. However, talk to your doctor if you experience these side effects persistently.

Please tell your doctor if you are allergic to Nuroplus-D3 Tablet or its components. Let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother. Nuroplus-D3 Tablet may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Nuroplus-D3 Tablet as it could lead to increased dizziness and sleepiness. Safety and efficacy of Nuroplus-D3 Tablet have not been established in patients younger than 18 years. 

Nuroplus-D3 Tablet contains Pregabalin, Nortriptyline, Methylcobalamin, and Cholecalciferol. Pregabalin works by binding to the specific site on voltage-gated calcium channels, thus helping to relieve nerve pain. Nortriptyline increases the levels of nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Methylcobalamin regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Cholecalciferol promotes a neuroprotective effect and prevents the progression of nerve damage.

Let your doctor know if you have any blood disorders, chronic obstructive pulmonary disease (COPD), liver/kidney/heart diseases, diabetes, mood disorders, schizophrenia, thyroid problems, glaucoma, Brugada syndrome (a genetic heart condition), fits, substance use disorder, angioedema (painless swelling under the skin) or receiving electroconvulsive treatment before starting Nuroplus-D3 Tablet . Pregnant and breastfeeding women should consult their doctor before taking Nuroplus-D3 Tablet . This medicine may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol during the treatment, as it could increase dizziness and sleepiness. Nuroplus-D3 Tablet should not be given to children as safety and effectiveness have not been established.