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  3. O-Tab 20 Tablet 10's

O-Tab 20 Tablet 10's, Pack of 10 TABLETS
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Hari Kumar , MBBS
Non returnable*
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Whats That

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Composition :

OMEPRAZOLE-20MG

Manufacturer/Marketer :

Xemex Life Sciences

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About O-Tab 20 Tablet

O-Tab 20 Tablet belongs to the class of drugs known as Proton pump inhibitor (PPIs), which reduces the amount of acid your stomach makes. It treats gastroesophageal reflux disease (GERD), stomach ulcer, and Zollinger Ellison syndrome (overproduction of acid due to pancreatic tumour).

O-Tab 20 Tablet contains omeprazole, which helps reduce stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the stomach wall cells and is responsible for releasing gastric acid secretion. O-Tab 20 Tablet prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.

O-Tab 20 Tablet is taken with food in a dose and duration as advised by the doctor. Your dose will depend on your condition and how you respond to the medicine. An adult taking O-Tab 20 Tablet might have common side effects like stomach pain, gas formation (flatulence), nausea, vomiting, diarrhoea, and headache. Respiratory system problems can be reported in some children (more than 1 year) using O-Tab 20 Tablet . These side effects are temporary and may get resolved after some time; however, if this side persists, contact the doctor.

O-Tab 20 Tablet should not be given to the patient suffering from Clostridium difficile-associated diarrhoea. O-Tab 20 Tablet is safe for pregnant and breastfeeding mothers but should be taken only after consulting a doctor. Tell your doctor if you have stomach or intestinal cancer, liver problem, are allergic to O-Tab 20 Tablet , or will have an endoscopy in the future. Ask your doctor if you should stop taking O-Tab 20 Tablet a few weeks before your endoscopy as it may hide some of the problems that would be spotted during an endoscopy. Prolonged use of O-Tab 20 Tablet may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist or spine due to loss of magnesium. Avoid using O-Tab 20 Tablet with St John’s Wort (plant-based antidepressant), rifampin (antibiotic) and methotrexate (anti-cancer and anti-arthritis medicine) due to the severe drug interaction.

Uses of O-Tab 20 Tablet

Stomach ulcers, Acid reflux (Gastroesophageal Reflux Disease - GERD), Hyperacidity, Zollinger Ellison syndrome

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Oral Suspension: Shake the bottle well before use. Check the label for directions and take O-Tab 20 Tablet in doses as prescribed by your doctor with the help of a measuring cup/dropper provided by the pack.Powder/granules: Check the label for directions before use. Mix the powder/granules in water, mix well and drink immediately.

Medicinal Benefits

O-Tab 20 Tablet is effective at healing erosive esophagitis (inflammation of food pipe), relieving symptoms of gastroesophageal reflux disease (heartburn), and Zollinger-Ellison syndrome, stomach ulcers. O-Tab 20 Tablet works by irreversibly blocking the proton pump gate (which secretes stomach acid). It can be prescribed to all age groups, including special populations like the elderly, pregnant mothers, and kidney and liver disease patients. Usually, no dosage adjustment is required for these groups. It should not be given to children less than one year of age as no clinical studies have been done.

Storage

Keep O-Tab 20 Tablet out of the sight and reach of children.

Drug Warnings

O-Tab 20 Tablet should not be given to the patient suffering from Clostridium difficile-associated diarrhoea. O-Tab 20 Tablet is safe for pregnant and breastfeeding mothers but should be taken only after consulting a doctor. Tell your doctor if you have stomach or intestinal cancer, liver problem, are allergic to O-Tab 20 Tablet or will have an endoscopy in the future. Ask your doctor if you should stop taking O-Tab 20 Tablet a few weeks before your endoscopy as it may hide some of the problems that would be spotted during an endoscopy. Prolonged use of O-Tab 20 Tablet may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist or spine due to loss of magnesium. Avoid using O-Tab 20 Tablet with St John’s Wort (plant-based antidepressant), rifampin (antibiotic) and methotrexate (anti-cancer and anti-arthritis medicine) due to the severe drug interaction.

Drug-Drug Interactions

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OmeprazoleErlotinib
Critical
OmeprazoleRilpivirine
Critical

Drug-Drug Interactions

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OmeprazoleErlotinib
Critical
How does the drug interact with O-Tab 20 Tablet:
O-Tab 20 Tablet can make Erlotinib less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking O-Tab 20 Tablet and Erlotinib together is not recommended as it can result in an interaction; it should be taken only if a doctor has advised it. Do not stop using any medications without talking to a doctor.
OmeprazoleRilpivirine
Critical
How does the drug interact with O-Tab 20 Tablet:
Using rilpivirine together with O-Tab 20 Tablet can decrease the absorption and blood levels of rilpivirine.

How to manage the interaction:
Taking O-Tab 20 Tablet with Rilpivirine can cause an interaction, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
OmeprazolePazopanib
Severe
How does the drug interact with O-Tab 20 Tablet:
O-Tab 20 Tablet may interfere with pazopanib absorption and reduces its effectiveness.

How to manage the interaction:
Although taking O-Tab 20 Tablet with pazopanib can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
OmeprazoleDasatinib
Severe
How does the drug interact with O-Tab 20 Tablet:
Taking O-Tab 20 Tablet and Dasatinib together may decrease the blood levels of Dasatinib.

How to manage the interaction:
Although taking O-Tab 20 Tablet with Dasatinib can lead to interaction, they can be taken if recommended by a doctor. If you experience any unusual symptoms, visit a doctor. Do not stop using any medications without talking to a doctor.
OmeprazoleAtazanavir
Severe
How does the drug interact with O-Tab 20 Tablet:
When taken together, O-Tab 20 Tablet, through decreasing stomach acid, can reduce atazanavir absorption and blood levels, making the medication less effective.

How to manage the interaction:
Although taking O-Tab 20 Tablet with atazanavir can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
OmeprazoleAcalabrutinib
Severe
How does the drug interact with O-Tab 20 Tablet:
O-Tab 20 Tablet, through decreasing stomach acidity, may interfere with the absorption of acalabrutinib capsules and reduce their effectiveness.

How to manage the interaction:
Although taking O-Tab 20 Tablet with acalabrutinib can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
OmeprazoleCitalopram
Severe
How does the drug interact with O-Tab 20 Tablet:
When O-Tab 20 Tablet is used with citalopram the blood levels of citalopram may increase, increasing the risk of certain adverse effects, such as an abnormal heart rhythm, which can be serious.

How to manage the interaction:
Although taking O-Tab 20 Tablet and citalopram together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid/pounding heartbeats while taking these medications, consult the doctor. Do not stop using any medications without talking to a doctor.
OmeprazoleMesalazine
Severe
How does the drug interact with O-Tab 20 Tablet:
Co-administration of O-Tab 20 Tablet with mesalazine can decrease the effects of mesalazine.

How to manage the interaction:
There could be a possible interaction between Mesalazine and O-Tab 20 Tablet, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
OmeprazoleTacrolimus
Severe
How does the drug interact with O-Tab 20 Tablet:
Taking tacrolimus with O-Tab 20 Tablet may significantly increase the blood levels of tacrolimus, which may increase the risk of serious side effects (high sugars, infections, kidney problems, hyperkalemia - high blood levels of potassium).

How to manage the interaction:
Although taking O-Tab 20 Tablet with tacrolimus can lead to interaction, they can be taken if recommended by a doctor. However, consult the doctor if you experience irregular heart rhythm, palpitations (fast heartbeat), muscle spasm, tremor (shaking of hands & legs), and seizures(fits). Do not stop using any medications without talking to a doctor.
OmeprazoleClopidogrel
Severe
How does the drug interact with O-Tab 20 Tablet:
When taken together O-Tab 20 Tablet can lower the levels of Clopidogrel in the blood, which can result in a decreased effectiveness of clopidogrel.

How to manage the interaction:
Taking O-Tab 20 Tablet and clopidogrel together has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
  • Before going to sleep try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows, instead, one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid taking alcohol and smoking cigarette. Alcohol can raise the level of production of stomach acid leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter) which prevents backflow of the stomach acid back into the food pipe.
  • Include high fibre containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal. These foods are full of antioxidant, calcium and vitamin B 12 that can help cope with the long term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production. Cranberry juice can be beneficial in the peptic ulcer and H Pyroli infection.
  • Avoid regular sitting continuously, as it can increase stomach acid production. Try to take a break of 5 minutes in 1 hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS

O-Tab 20 Tablet Substitute

Substitutes safety advice

Product Substitutes

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Hari Kumar

Reviewed By

Hari Kumar

MBBS

Last Updated

Jul 8, 2025 | 9:29 AM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

O-Tab 20 Tablet is a type of medicine called a proton pump inhibitor (PPI). Proton pumps are enzymes in your stomach lining that help it make acid to digest food. Omeprazole prevents the proton pump from working properly. This reduces the amount of acid the stomach makes, relieving symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.

Prolonged intake of O-Tab 20 Tablet may weaken your bone and lower haemoglobin level. Your doctor may prescribe you Vitamin B-12 for enhancing haemoglobin and calcium/vitamin D/magnesium supplements for bone health.

Prolonged intake of O-Tab 20 Tablet may lead to atrophic gastritis (inflammation of stomach cells), Vitamin B12 deficiency and weakening of bones or osteoporosis (loss of calcium, magnesium and vitamin D). Your doctor may prescribe calcium, vitamin D or haemoglobin enhancing medications to cope with long term side effects.

No. O-Tab 20 Tablet is not prescribed for stomach cancer. Do not take O-Tab 20 Tablet until your doctor has prescribed you. O-Tab 20 Tablet is only indicated for the treatment of hyperacidity, acid reflux symptoms (GERD), heartburn and Zollinger Ellison syndrome.

No. Gas and acidity are two different common discomforts. Acidity is caused when improper functioning of the valve (sphincter) is located at the junction of the stomach and food pipe. As a result stomach acid backflows and enters the upper part of the food pipe causing heartburn. On the other hand, gas is the result of the digestion of the food and drinks eliminating gases like carbon dioxide, hydrogen, nitrogen, methane, etc. from the body.

Yes. O-Tab 20 Tablet can alter certain medical tests like neuroendocrine tumours (secretin stimulation test), and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such diagnostics test contact your doctor.

No. O-Tab 20 Tablet prevents excess production of stomach acid, causing acid reflux and heartburn. If blood is coming in your stool or mucous, immediately contact the doctor.

Drug-Drug Interactions Checker List

  • CLOPIDOGREL
  • WARFARIN
  • KETOCONAZOLE
  • VORICONAZOLE
  • ITRACONAZOLE
  • POSACONAZOLE
  • ATAZANAVIR
  • NELFINAVIR
  • AMPICILLIN
  • RIFAMPICIN
  • DIGOXIN
  • METHOTREXATE

Disease/Condition Glossary

Normally a thick layer of mucous protects the stomach against its own acid secretion. But, in the long run, it gets eroded by excessive stomach acid production leading to complications like GERD, peptic ulcer, and Zollinger Ellison syndrome. Gastroesophageal reflux disease (GERD) is a gastrointestinal disorder that occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe that causes heartburn. On the other hand, a peptic ulcer is a painful condition followed by the development of sores or ulcers in the stomach lining or duodenum (first part of the small intestine) (the duodenum). Zollinger Ellison syndrome is a rare condition in which a gastrin-secreting pancreas tumour causes excessive acid production leading to peptic ulcers.

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